| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Everolimus perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Everolimus_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.257624 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.221502 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.160214 |
| PTMA | prothymosin, alpha | 0.148352 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.120034 |
| MYO1E | myosin IE | 0.101233 |
| LMO7 | LIM domain 7 | 0.0990979 |
| LDHA | lactate dehydrogenase A | 0.0916824 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0828915 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0776526 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.076521 |
| RPS12 | ribosomal protein S12 | 0.0727819 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0723356 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0695712 |
| NEBL | nebulette | 0.0617354 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0608243 |
| RPS8 | ribosomal protein S8 | 0.0569573 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0553403 |
| ENO1 | enolase 1, (alpha) | 0.0546047 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0537846 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0535189 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0504915 |
| B2M | beta-2-microglobulin | 0.0504336 |
| KRT18 | keratin 18, type I | 0.048572 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0457031 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0444015 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0425414 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0421179 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0402986 |
| MUC13 | mucin 13, cell surface associated | 0.0397395 |
| PDZD8 | PDZ domain containing 8 | 0.0389819 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0388734 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0385917 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0385778 |
| MT2A | metallothionein 2A | 0.0374004 |
| AFF1 | AF4/FMR2 family, member 1 | 0.036379 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0353119 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0351347 |
| SIK3 | SIK family kinase 3 | 0.0348612 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0345542 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0344187 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0335686 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0331173 |
| CRY1 | cryptochrome circadian clock 1 | 0.0329341 |
| DSPP | dentin sialophosphoprotein | 0.0319792 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0317257 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0317075 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0315895 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0314433 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0309715 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.030919 |
| RPS2 | ribosomal protein S2 | 0.0307985 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0306191 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0303217 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0301878 |
| MYO5B | myosin VB | 0.0300062 |
| RIGI | RNA sensor RIG-I | 0.029995 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0294822 |
| RPS7 | ribosomal protein S7 | 0.0292629 |
| TFF1 | trefoil factor 1 | 0.0292567 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0291076 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.02896 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0288962 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0286924 |
| KLF6 | Kruppel-like factor 6 | 0.0285714 |
| CALR | calreticulin | 0.0285577 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0284383 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0281708 |
| EREG | epiregulin | 0.0278235 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0270016 |
| MT1E | metallothionein 1E | 0.0269875 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0269197 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0268709 |
| MUC17 | mucin 17, cell surface associated | 0.0264725 |
| SSR1 | signal sequence receptor, alpha | 0.0264082 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0261956 |
| NUCB2 | nucleobindin 2 | 0.0260113 |
| RPLP0 | ribosomal protein, large, P0 | 0.0256535 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0254113 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0250808 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0246828 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.024575 |
| TPI1 | triosephosphate isomerase 1 | 0.0245717 |
| RPL18 | ribosomal protein L18 | 0.0243113 |
| RPL7 | ribosomal protein L7 | 0.0241948 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0238322 |
| MED13 | mediator complex subunit 13 | 0.0238278 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0237203 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0236891 |
| TUBA1B | tubulin, alpha 1b | 0.0236055 |
| MLEC | malectin | 0.0229649 |
| TMC5 | transmembrane channel-like 5 | 0.0229634 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0229109 |
| RC3H1 | ring finger and CCCH-type domains 1 | 0.0227416 |
| RACK1 | receptor for activated C kinase 1 | 0.0226552 |
| SQSTM1 | sequestosome 1 | 0.0226456 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0225032 |
| RPL26 | ribosomal protein L26 | 0.0224731 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0224382 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0224065 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.213041 |
| NPSR1 | neuropeptide S receptor 1 | -0.175704 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.141585 |
| TNS4 | tensin 4 | -0.128725 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.105439 |
| NDRG1 | N-myc downstream regulated 1 | -0.0908654 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0861513 |
| AHNAK | AHNAK nucleoprotein | -0.0838218 |
| VCL | vinculin | -0.080075 |
| FLNB | filamin B, beta | -0.077065 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0759381 |
| RPL35A | ribosomal protein L35a | -0.0740053 |
| RNF43 | ring finger protein 43 | -0.070807 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.06926 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0645057 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0587016 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0580271 |
| H1-0 | H1.0 linker histone | -0.0579954 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0555859 |
| ACTN4 | actinin, alpha 4 | -0.0552539 |
| TMSB10 | thymosin beta 10 | -0.0544293 |
| PIGR | polymeric immunoglobulin receptor | -0.0542605 |
| GPHN | gephyrin | -0.0540709 |
| ITGA6 | integrin, alpha 6 | -0.0533902 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0495807 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0493493 |
| EGR1 | early growth response 1 | -0.0487023 |
| ACTG1 | actin gamma 1 | -0.0477327 |
| ANXA2 | annexin A2 | -0.046939 |
| CALB1 | calbindin 1, 28kDa | -0.0461346 |
| ASPH | aspartate beta-hydroxylase | -0.0452288 |
| RBM39 | RNA binding motif protein 39 | -0.044812 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0430164 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.042738 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0424555 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0422089 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0410279 |
| POTEF | POTE ankyrin domain family, member F | -0.0404432 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0402288 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0396509 |
| RPL11 | ribosomal protein L11 | -0.0393658 |
| ATF4 | activating transcription factor 4 | -0.0393216 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0383053 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0368863 |
| CADPS | Ca++-dependent secretion activator | -0.0367399 |
| RPS6 | ribosomal protein S6 | -0.0354317 |
| DENND1A | DENN/MADD domain containing 1A | -0.0353884 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0352589 |
| LAMA4 | laminin, alpha 4 | -0.0352257 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0343783 |
| EHBP1 | EH domain binding protein 1 | -0.0343471 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.033996 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0339639 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0336285 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0330771 |
| RIN2 | Ras and Rab interactor 2 | -0.0321009 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0320319 |
| RPS23 | ribosomal protein S23 | -0.0308631 |
| HMGA1 | high mobility group AT-hook 1 | -0.0305888 |
| MSI2 | musashi RNA-binding protein 2 | -0.0304229 |
| FERMT1 | fermitin family member 1 | -0.0294855 |
| YBX1 | Y box binding protein 1 | -0.0290671 |
| ITGB4 | integrin, beta 4 | -0.0290487 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0286439 |
| KRT8 | keratin 8, type II | -0.0286096 |
| RBM25 | RNA binding motif protein 25 | -0.0285148 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0284488 |
| ONECUT3 | one cut homeobox 3 | -0.028377 |
| VMP1 | vacuole membrane protein 1 | -0.0280309 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0277257 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0277218 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0276306 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0276005 |
| RAD51B | RAD51 paralog B | -0.0275306 |
| INSIG1 | insulin induced gene 1 | -0.0271224 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0271079 |
| RPS29 | ribosomal protein S29 | -0.0269594 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0266958 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0266822 |
| SETD5 | SET domain containing 5 | -0.0264643 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | -0.0264642 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0260921 |
| MED13L | mediator complex subunit 13-like | -0.0259148 |
| TXNRD1 | thioredoxin reductase 1 | -0.0259042 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0257853 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0256979 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0253974 |
| RPL34 | ribosomal protein L34 | -0.0253004 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0252079 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0247809 |
| BCL2L1 | BCL2-like 1 | -0.0245988 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0245944 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0245795 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0245708 |
| TMEM135 | transmembrane protein 135 | -0.0244561 |
| RPS19 | ribosomal protein S19 | -0.0244489 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0244483 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0243049 |
| FHIT | fragile histidine triad | -0.024122 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.024087 |
