| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Everolimus perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Everolimus_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.23794 |
| MT2A | metallothionein 2A | 0.16211 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0827255 |
| RPS12 | ribosomal protein S12 | 0.0811816 |
| MT1E | metallothionein 1E | 0.0809368 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0741919 |
| RPS8 | ribosomal protein S8 | 0.0731828 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0689866 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0684915 |
| ANGPTL4 | angiopoietin-like 4 | 0.0656313 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0655786 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0639899 |
| RPL12 | ribosomal protein L12 | 0.0638583 |
| SPAG9 | sperm associated antigen 9 | 0.061267 |
| CAPRIN2 | caprin family member 2 | 0.0590121 |
| RPL36 | ribosomal protein L36 | 0.0577213 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0573546 |
| TXNIP | thioredoxin interacting protein | 0.0556288 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0549324 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0539946 |
| SP100 | SP100 nuclear antigen | 0.0531199 |
| SEC24A | SEC24 family member A | 0.0500792 |
| FTL | ferritin, light polypeptide | 0.0499463 |
| RPS27 | ribosomal protein S27 | 0.0497329 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0489436 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0488813 |
| EZR | ezrin | 0.0475506 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0452692 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0448947 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.044788 |
| RPL27 | ribosomal protein L27 | 0.0447748 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0435357 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0426007 |
| LDHA | lactate dehydrogenase A | 0.0410427 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0395132 |
| B2M | beta-2-microglobulin | 0.0389776 |
| RPS19 | ribosomal protein S19 | 0.0384777 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0375017 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0371107 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0369192 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0368996 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0367554 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0367253 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0363037 |
| HOMER1 | homer scaffolding protein 1 | 0.0362161 |
| DST | dystonin | 0.0361513 |
| SQSTM1 | sequestosome 1 | 0.0358559 |
| ZNF292 | zinc finger protein 292 | 0.0355764 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0345551 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0345404 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0344301 |
| SLK | STE20-like kinase | 0.0340571 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0334225 |
| RPL28 | ribosomal protein L28 | 0.033348 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0331931 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0331291 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0328037 |
| RPL36A | ribosomal protein L36a | 0.0325168 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0324523 |
| RPS17 | ribosomal protein S17 | 0.0324256 |
| RPLP2 | ribosomal protein, large, P2 | 0.0320504 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0318871 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0318777 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0318485 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0317175 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0309695 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0306573 |
| RPL26 | ribosomal protein L26 | 0.0306095 |
| JMJD1C | jumonji domain containing 1C | 0.030509 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0300487 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0299462 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0296157 |
| RPS3 | ribosomal protein S3 | 0.0295642 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0291152 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0290035 |
| ZNF148 | zinc finger protein 148 | 0.0279139 |
| SON | SON DNA binding protein | 0.0278926 |
| RTTN | rotatin | 0.0274592 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0274358 |
| RPL39 | ribosomal protein L39 | 0.0273189 |
| RPS7 | ribosomal protein S7 | 0.0272974 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0271116 |
| YEATS2 | YEATS domain containing 2 | 0.0270829 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0270177 |
| SEPTIN2 | septin 2 | 0.0269583 |
| VEGFC | vascular endothelial growth factor C | 0.0266023 |
| SNX3 | sorting nexin 3 | 0.0264966 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0263098 |
| PKM | pyruvate kinase, muscle | 0.0262275 |
| RPS25 | ribosomal protein S25 | 0.0258281 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.025785 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0257239 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0256627 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0254992 |
| RPL37 | ribosomal protein L37 | 0.0254403 |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.0254325 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0251449 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.024964 |
| RUNX1 | runt-related transcription factor 1 | 0.0249367 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0249022 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.259842 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.153703 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.134193 |
| CD44 | CD44 molecule (Indian blood group) | -0.130517 |
| AHNAK | AHNAK nucleoprotein | -0.127388 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.109233 |
| UBC | ubiquitin C | -0.101066 |
| TMSB10 | thymosin beta 10 | -0.0831811 |
| ACTG1 | actin gamma 1 | -0.0786061 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0780351 |
| TMSB4X | thymosin beta 4, X-linked | -0.072542 |
| APP | amyloid beta (A4) precursor protein | -0.0709986 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.065902 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0633208 |
| FLNB | filamin B, beta | -0.0615348 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0607248 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0603191 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0581118 |
| HLA-B | major histocompatibility complex, class I, B | -0.0570752 |
| TNS3 | tensin 3 | -0.0567899 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0560879 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0520171 |
| DOCK11 | dedicator of cytokinesis 11 | -0.0511572 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0479642 |
| ZNF217 | zinc finger protein 217 | -0.046486 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0464853 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0451384 |
| PODXL | podocalyxin-like | -0.0451306 |
| CANX | calnexin | -0.0450565 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0445651 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0445198 |
| RPL35A | ribosomal protein L35a | -0.0444549 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0417424 |
| STK17A | serine/threonine kinase 17a | -0.0411887 |
| EHBP1 | EH domain binding protein 1 | -0.0404721 |
| SRGN | serglycin | -0.0399263 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0397814 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.037522 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.036734 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0360694 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0354525 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0337901 |
| RBM39 | RNA binding motif protein 39 | -0.0337757 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.033558 |
| CADM2 | cell adhesion molecule 2 | -0.0335503 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0333878 |
| NAV2 | neuron navigator 2 | -0.032754 |
| LRRC49 | leucine rich repeat containing 49 | -0.0326564 |
| S100A10 | S100 calcium binding protein A10 | -0.032608 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0325039 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.031867 |
| MT1X | metallothionein 1X | -0.0318614 |
| PTMA | prothymosin, alpha | -0.0314851 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0308292 |
| RBMX | RNA binding motif protein, X-linked | -0.0306215 |
| FMNL2 | formin-like 2 | -0.0305803 |
| RAI1 | retinoic acid induced 1 | -0.0300158 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.029905 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0298892 |
| RPS27A | ribosomal protein S27a | -0.0293284 |
| CENPF | centromere protein F, 350/400kDa | -0.0287964 |
| EMP1 | epithelial membrane protein 1 | -0.0287486 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0286114 |
| TMEM123 | transmembrane protein 123 | -0.0285768 |
| SCGB1D1 | secretoglobin, family 1D, member 1 | -0.0285335 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0284269 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0283524 |
| PGK1 | phosphoglycerate kinase 1 | -0.0282771 |
| MYOF | myoferlin | -0.0281873 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0280874 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0277624 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0277404 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0276211 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.027395 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.027002 |
| EPHA4 | EPH receptor A4 | -0.0269067 |
| SMAD3 | SMAD family member 3 | -0.0264913 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0263867 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0259011 |
| RPL4 | ribosomal protein L4 | -0.0257183 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0255925 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0255279 |
| RIGI | RNA sensor RIG-I | -0.0250179 |
| FBXO11 | F-box protein 11 | -0.0249569 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0246801 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.0246588 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0243945 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0242317 |
| RBM25 | RNA binding motif protein 25 | -0.0242018 |
| NEK10 | NIMA-related kinase 10 | -0.0239875 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0236378 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.023534 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0234936 |
| RASAL2 | RAS protein activator like 2 | -0.0233649 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0233565 |
| IGF2 | insulin-like growth factor 2 | -0.0231579 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0231507 |
| EFNA5 | ephrin-A5 | -0.0230822 |
| VIM | vimentin | -0.0225553 |
| CFDP1 | craniofacial development protein 1 | -0.0223306 |
