| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Everolimus perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Everolimus_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.16354 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.138438 |
| SLTM | SAFB-like, transcription modulator | 0.115396 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.112507 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.103894 |
| ENO1 | enolase 1, (alpha) | 0.102209 |
| LDHA | lactate dehydrogenase A | 0.0958614 |
| STC1 | stanniocalcin 1 | 0.0891176 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0853216 |
| CPE | carboxypeptidase E | 0.0832911 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0802372 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0786922 |
| FAM13A | family with sequence similarity 13, member A | 0.07578 |
| RPS3 | ribosomal protein S3 | 0.0677034 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0661386 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0608378 |
| RPS12 | ribosomal protein S12 | 0.0603277 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0598714 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0553674 |
| PTMA | prothymosin, alpha | 0.0537231 |
| AREG | amphiregulin | 0.0537176 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0469963 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0468732 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0466372 |
| RPS17 | ribosomal protein S17 | 0.046511 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0463115 |
| EGR1 | early growth response 1 | 0.046251 |
| HYOU1 | hypoxia up-regulated 1 | 0.045815 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0435707 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0419367 |
| MT2A | metallothionein 2A | 0.0418115 |
| RPL37A | ribosomal protein L37a | 0.0403503 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0389808 |
| RPS8 | ribosomal protein S8 | 0.0386762 |
| MCL1 | myeloid cell leukemia 1 | 0.0378448 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0377937 |
| SP100 | SP100 nuclear antigen | 0.0376343 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0376043 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0365773 |
| RNF213 | ring finger protein 213 | 0.0362246 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0356803 |
| B2M | beta-2-microglobulin | 0.0354429 |
| PKM | pyruvate kinase, muscle | 0.0352368 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0347743 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0333937 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.032186 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0316836 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0311656 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.0311403 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0304183 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0301166 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0291183 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0291082 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0285824 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0281055 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0280742 |
| ANGPTL4 | angiopoietin-like 4 | 0.0277989 |
| SLK | STE20-like kinase | 0.0276379 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0271359 |
| RPLP0 | ribosomal protein, large, P0 | 0.0264624 |
| RPS25 | ribosomal protein S25 | 0.0263004 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0258914 |
| PMP22 | peripheral myelin protein 22 | 0.0256449 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0256339 |
| ITSN2 | intersectin 2 | 0.0256331 |
| RPL37 | ribosomal protein L37 | 0.025618 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0253758 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0253083 |
| RPL30 | ribosomal protein L30 | 0.0248807 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0246603 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0245172 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0242417 |
| PYGL | phosphorylase, glycogen, liver | 0.0242337 |
| YBX3 | Y box binding protein 3 | 0.02416 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0241432 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0240143 |
| DTNA | dystrobrevin, alpha | 0.0239323 |
| TMEM45B | transmembrane protein 45B | 0.0237182 |
| RPS2 | ribosomal protein S2 | 0.0234421 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0234364 |
| HOMER1 | homer scaffolding protein 1 | 0.0234118 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.02341 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0232771 |
| IFI44L | interferon-induced protein 44-like | 0.0232547 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0231624 |
| RPS7 | ribosomal protein S7 | 0.0231159 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0230755 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0228164 |
| CAV2 | caveolin 2 | 0.0226793 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0226166 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0224727 |
| S100P | S100 calcium binding protein P | 0.0221736 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0218532 |
| CST3 | cystatin C | 0.0218325 |
| CD163L1 | CD163 molecule-like 1 | 0.0217813 |
| MXI1 | MAX interactor 1, dimerization protein | 0.021762 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0215079 |
| TPI1 | triosephosphate isomerase 1 | 0.0214537 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0214512 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0213329 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.247247 |
| ASPH | aspartate beta-hydroxylase | -0.189765 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.153994 |
| LAMC2 | laminin, gamma 2 | -0.125928 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.124112 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.117622 |
| AHNAK | AHNAK nucleoprotein | -0.10393 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0937022 |
| OSMR | oncostatin M receptor | -0.0905626 |
| H1-0 | H1.0 linker histone | -0.0866597 |
| NDRG1 | N-myc downstream regulated 1 | -0.0843364 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0781518 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0742323 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0720087 |
| NABP1 | nucleic acid binding protein 1 | -0.0712002 |
| ACTG1 | actin gamma 1 | -0.0684481 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0679657 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.066875 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0656116 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0607559 |
| LAMA4 | laminin, alpha 4 | -0.0597545 |
| VCL | vinculin | -0.0586491 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0563473 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0555202 |
| UBC | ubiquitin C | -0.0548708 |
| SCEL | sciellin | -0.0519024 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0504489 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0500108 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0488331 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0487748 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.046867 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0461341 |
| KRT8 | keratin 8, type II | -0.0438724 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0414277 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0410868 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0409579 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0409494 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0405364 |
| CANX | calnexin | -0.040086 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0397893 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0397448 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0394967 |
| NDE1 | nudE neurodevelopment protein 1 | -0.0391444 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0390506 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0389599 |
| ANXA2 | annexin A2 | -0.0375681 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0373624 |
| EFNA5 | ephrin-A5 | -0.0372037 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0370325 |
| NF1 | neurofibromin 1 | -0.0368514 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0367075 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0360798 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0352984 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0348873 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.034019 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0339877 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0337091 |
| RBM39 | RNA binding motif protein 39 | -0.0330085 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.032716 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0319973 |
| FBXO11 | F-box protein 11 | -0.0313777 |
| GM2A | GM2 ganglioside activator | -0.0312765 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0312362 |
| TNS3 | tensin 3 | -0.0312064 |
| FLNB | filamin B, beta | -0.0312039 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0310951 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0310659 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0307011 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0303206 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0301211 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0296214 |
| CCNL1 | cyclin L1 | -0.0296024 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0293424 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0292686 |
| PGK1 | phosphoglycerate kinase 1 | -0.0287761 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0287506 |
| HDLBP | high density lipoprotein binding protein | -0.0282134 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0281982 |
| FRYL | FRY-like | -0.0279197 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0277406 |
| MKI67 | marker of proliferation Ki-67 | -0.0276817 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0275813 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0273908 |
| BBX | bobby sox homolog (Drosophila) | -0.0272332 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0267488 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0265351 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0261379 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0256531 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0256514 |
| NPTN | neuroplastin | -0.0254981 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0254339 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0253303 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.025256 |
| KRT7 | keratin 7, type II | -0.0252146 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0251183 |
| SBF2 | SET binding factor 2 | -0.0250953 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0250628 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.025013 |
| SHTN1 | shootin 1 | -0.0249194 |
| LMO7 | LIM domain 7 | -0.024649 |
