| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Everolimus perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Everolimus_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ANGPTL4 | angiopoietin-like 4 | 0.130748 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.120852 |
| HMGA2 | high mobility group AT-hook 2 | 0.115263 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0973707 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0912526 |
| VIM | vimentin | 0.091196 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0873599 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0823533 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0788779 |
| RPS12 | ribosomal protein S12 | 0.0786806 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0753799 |
| CA12 | carbonic anhydrase XII | 0.074734 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.072881 |
| IFI44L | interferon-induced protein 44-like | 0.0713243 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0625834 |
| PLIN2 | perilipin 2 | 0.0614917 |
| ENO1 | enolase 1, (alpha) | 0.0598072 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0585099 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0583311 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0574059 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0552127 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0548801 |
| PRELID2 | PRELI domain containing 2 | 0.0536992 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0532403 |
| MT2A | metallothionein 2A | 0.052666 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0517612 |
| LDHA | lactate dehydrogenase A | 0.0514062 |
| ADD3 | adducin 3 (gamma) | 0.0512054 |
| FAM20C | family with sequence similarity 20, member C | 0.0509819 |
| SIK3 | SIK family kinase 3 | 0.0509164 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0499819 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.049888 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0497583 |
| LOX | lysyl oxidase | 0.0495519 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0489241 |
| NAV2 | neuron navigator 2 | 0.048632 |
| B2M | beta-2-microglobulin | 0.047761 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0467904 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0437391 |
| GLCCI1 | glucocorticoid induced 1 | 0.0418017 |
| FAM13A | family with sequence similarity 13, member A | 0.0411114 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0410912 |
| MTSS1 | metastasis suppressor 1 | 0.0410165 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0403787 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0402927 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0397677 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0395078 |
| ASPH | aspartate beta-hydroxylase | 0.0390518 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0387653 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0386977 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0370134 |
| LOXL2 | lysyl oxidase-like 2 | 0.0368453 |
| ZNF638 | zinc finger protein 638 | 0.0365321 |
| PKM | pyruvate kinase, muscle | 0.0361003 |
| EFNA5 | ephrin-A5 | 0.0358615 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0357605 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0354639 |
| INTS6 | integrator complex subunit 6 | 0.0345831 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0345413 |
| SP100 | SP100 nuclear antigen | 0.0343817 |
| RPS3 | ribosomal protein S3 | 0.0340665 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0329979 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0325653 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0319448 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0319151 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.031892 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0317802 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0305029 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0302596 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.030193 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0298843 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0298722 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0298256 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0297772 |
| VEGFC | vascular endothelial growth factor C | 0.0295409 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0295398 |
| TOP1 | topoisomerase (DNA) I | 0.0293773 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0291679 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0290335 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0289305 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0284773 |
| RPS17 | ribosomal protein S17 | 0.0284052 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0279982 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0279722 |
| EHBP1 | EH domain binding protein 1 | 0.0275248 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0272004 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0270342 |
| NRP1 | neuropilin 1 | 0.0269787 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0267324 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0263247 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0262978 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0262764 |
| MEF2A | myocyte enhancer factor 2A | 0.0262016 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0261675 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0261179 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0260923 |
| WWOX | WW domain containing oxidoreductase | 0.0260166 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0256718 |
| SEPTIN9 | septin 9 | 0.0255474 |
| DTNA | dystrobrevin, alpha | 0.0252574 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.205978 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.172965 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.14931 |
| TMSB10 | thymosin beta 10 | -0.145235 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.116558 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.116149 |
| RBM39 | RNA binding motif protein 39 | -0.103061 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.101274 |
| CD44 | CD44 molecule (Indian blood group) | -0.0910788 |
| RPL35A | ribosomal protein L35a | -0.0879217 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0789342 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0742474 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0708502 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0684886 |
| GOLGA4 | golgin A4 | -0.066309 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0615472 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0614378 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0597914 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0587483 |
| OSMR | oncostatin M receptor | -0.055249 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0545908 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0533982 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.051217 |
| NDRG1 | N-myc downstream regulated 1 | -0.0501294 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0494281 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0492851 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.046321 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0456677 |
| ACTG1 | actin gamma 1 | -0.0447539 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0438901 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0434306 |
| FN1 | fibronectin 1 | -0.0418333 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0401138 |
| OPTN | optineurin | -0.0400072 |
| CANX | calnexin | -0.0391399 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0390067 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0382016 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0380091 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.036059 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0360515 |
| RPS19 | ribosomal protein S19 | -0.0360232 |
| CALU | calumenin | -0.0355577 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0354275 |
| RPL34 | ribosomal protein L34 | -0.03489 |
| IER3 | immediate early response 3 | -0.034797 |
| OGA | O-GlcNAcase | -0.0344819 |
| PTMA | prothymosin, alpha | -0.034395 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0343907 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0342876 |
| SBF2 | SET binding factor 2 | -0.0340821 |
| EGR1 | early growth response 1 | -0.0338355 |
| SPAG9 | sperm associated antigen 9 | -0.0338334 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.033725 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0331662 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0326923 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.03247 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0318224 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0317168 |
| AHNAK | AHNAK nucleoprotein | -0.0314531 |
| ATG7 | autophagy related 7 | -0.0310464 |
| RPS11 | ribosomal protein S11 | -0.0308021 |
| TAOK3 | TAO kinase 3 | -0.0304613 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0301949 |
| UBC | ubiquitin C | -0.0300195 |
| GLG1 | golgi glycoprotein 1 | -0.0298625 |
| ARF1 | ADP-ribosylation factor 1 | -0.029795 |
| ATF4 | activating transcription factor 4 | -0.0296399 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0296003 |
| DENND4A | DENN/MADD domain containing 4A | -0.0293831 |
| POTEF | POTE ankyrin domain family, member F | -0.029204 |
| GOLGA3 | golgin A3 | -0.0291759 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0290278 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0288711 |
| ARF4 | ADP-ribosylation factor 4 | -0.0283311 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0282112 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0282046 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0280743 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0280233 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0278708 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0275959 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0275587 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0275581 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0275541 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0273903 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0267326 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0265715 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0265578 |
| VRK2 | vaccinia related kinase 2 | -0.0264174 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0263845 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0262289 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0259999 |
| H1-0 | H1.0 linker histone | -0.0258969 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0258415 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0257892 |
| TNS3 | tensin 3 | -0.0257671 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0256716 |
| ATF6 | activating transcription factor 6 | -0.0255471 |
| CFDP1 | craniofacial development protein 1 | -0.0254822 |
| RPS6 | ribosomal protein S6 | -0.0254006 |
| WDR45B | WD repeat domain 45B | -0.0253307 |
