| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Everolimus perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Everolimus_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.215444 |
| GRAMD1B | GRAM domain containing 1B | 0.196259 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.18022 |
| PM20D1 | peptidase M20 domain containing 1 | 0.11358 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.108229 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.095937 |
| S100A6 | S100 calcium binding protein A6 | 0.0774731 |
| TXNRD1 | thioredoxin reductase 1 | 0.0764474 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0668247 |
| FAM107B | family with sequence similarity 107, member B | 0.0662681 |
| OSMR | oncostatin M receptor | 0.0605461 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0591734 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0490824 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0471733 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.045748 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 0.0449506 |
| VIM | vimentin | 0.0444065 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0425031 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0418331 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0416267 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0415448 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0413506 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0412055 |
| NRG1 | neuregulin 1 | 0.041124 |
| SIK3 | SIK family kinase 3 | 0.0400484 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.03912 |
| STC1 | stanniocalcin 1 | 0.0384098 |
| DSE | dermatan sulfate epimerase | 0.0382102 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0381453 |
| KYNU | kynureninase | 0.0380241 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.037862 |
| ANGPTL4 | angiopoietin-like 4 | 0.0376659 |
| HLA-B | major histocompatibility complex, class I, B | 0.0372905 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0372122 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0361848 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0354883 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0349331 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0347681 |
| HLA-E | major histocompatibility complex, class I, E | 0.0341465 |
| RPS12 | ribosomal protein S12 | 0.0337663 |
| HLA-A | major histocompatibility complex, class I, A | 0.0334304 |
| NTN4 | netrin 4 | 0.0331328 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0329161 |
| NEK7 | NIMA-related kinase 7 | 0.0328385 |
| GOLGA4 | golgin A4 | 0.0327707 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.032661 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0324814 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0322763 |
| PYGL | phosphorylase, glycogen, liver | 0.0320534 |
| ITSN2 | intersectin 2 | 0.0320125 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0317223 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0315341 |
| KIF5B | kinesin family member 5B | 0.0315003 |
| COPA | coatomer protein complex, subunit alpha | 0.0313336 |
| NCKAP1 | NCK-associated protein 1 | 0.0313222 |
| B2M | beta-2-microglobulin | 0.0312293 |
| RPS7 | ribosomal protein S7 | 0.0311875 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0310727 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0309821 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0309796 |
| GLG1 | golgi glycoprotein 1 | 0.0305946 |
| RPS17 | ribosomal protein S17 | 0.0304464 |
| KIF13A | kinesin family member 13A | 0.0301923 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0297058 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0291712 |
| GPHN | gephyrin | 0.0290392 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0290241 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.028742 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0286863 |
| LDHA | lactate dehydrogenase A | 0.0284703 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0281268 |
| EVI5 | ecotropic viral integration site 5 | 0.0280965 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0277507 |
| ITGB5 | integrin, beta 5 | 0.0277263 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.0275718 |
| IL6 | interleukin 6 | 0.0274906 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0273433 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0272737 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0270766 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0266146 |
| PSEN1 | presenilin 1 | 0.0264749 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0263817 |
| RPL26 | ribosomal protein L26 | 0.0263652 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0261084 |
| TPD52 | tumor protein D52 | 0.0258395 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0252757 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0251429 |
| USP37 | ubiquitin specific peptidase 37 | 0.0248814 |
| PHF21A | PHD finger protein 21A | 0.0246937 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0246592 |
| JMJD1C | jumonji domain containing 1C | 0.0245884 |
| CDCP1 | CUB domain containing protein 1 | 0.0245063 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0240236 |
| LONP2 | lon peptidase 2, peroxisomal | 0.0239966 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0239328 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0238846 |
| ZNF148 | zinc finger protein 148 | 0.0238707 |
| MED13 | mediator complex subunit 13 | 0.0238553 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0238013 |
| SVIL | supervillin | 0.0237324 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.260691 |
| ACTG1 | actin gamma 1 | -0.147993 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.127571 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.126597 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.104761 |
| FTL | ferritin, light polypeptide | -0.103858 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0982697 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0973659 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0808765 |
| AHNAK | AHNAK nucleoprotein | -0.0776944 |
| DST | dystonin | -0.0690044 |
| RAD51B | RAD51 paralog B | -0.0678123 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0660582 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0646733 |
| CMIP | c-Maf inducing protein | -0.0629453 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0623282 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0612386 |
| POTEF | POTE ankyrin domain family, member F | -0.0587755 |
| FMNL2 | formin-like 2 | -0.0574551 |
| IGF2 | insulin-like growth factor 2 | -0.0574294 |
| PTMA | prothymosin, alpha | -0.0573095 |
| PKM | pyruvate kinase, muscle | -0.0501134 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0499417 |
| TMSB10 | thymosin beta 10 | -0.0490632 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0485944 |
| YBX1 | Y box binding protein 1 | -0.0485562 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0480832 |
| RPL35A | ribosomal protein L35a | -0.0461851 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0448987 |
| DOCK4 | dedicator of cytokinesis 4 | -0.044371 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0437787 |
| NEGR1 | neuronal growth regulator 1 | -0.0425321 |
| HMGA1 | high mobility group AT-hook 1 | -0.0424999 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0419952 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0409276 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0403009 |
| UTRN | utrophin | -0.0399359 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0396948 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0392259 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.039196 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0391023 |
| PDE8A | phosphodiesterase 8A | -0.0363505 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0360586 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0359368 |
| RPS29 | ribosomal protein S29 | -0.0358278 |
| PRR16 | proline rich 16 | -0.0350886 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0345284 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0343437 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0340081 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0338755 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0334405 |
| TPM1 | tropomyosin 1 (alpha) | -0.0334096 |
| AK1 | adenylate kinase 1 | -0.0330755 |
| BICC1 | BicC family RNA binding protein 1 | -0.0328117 |
| THBS1 | thrombospondin 1 | -0.0327303 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0317064 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0313586 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0313208 |
| GNAS | GNAS complex locus | -0.0311002 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0302106 |
| S100A10 | S100 calcium binding protein A10 | -0.030122 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0297858 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0296815 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0291542 |
| EFNA5 | ephrin-A5 | -0.0291077 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0290154 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.028617 |
| VCL | vinculin | -0.0285146 |
| GLIS3 | GLIS family zinc finger 3 | -0.0284697 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0283719 |
| LDHB | lactate dehydrogenase B | -0.028073 |
| DEK | DEK proto-oncogene | -0.0280515 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.02775 |
| ECT2 | epithelial cell transforming 2 | -0.0277333 |
| FUS | FUS RNA binding protein | -0.0275634 |
| PRKCE | protein kinase C, epsilon | -0.0275632 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0274743 |
| IER3 | immediate early response 3 | -0.0271546 |
| FLNA | filamin A, alpha | -0.0270016 |
| UBC | ubiquitin C | -0.026827 |
| CANX | calnexin | -0.0265011 |
| HMGB1 | high mobility group box 1 | -0.0263117 |
| ACLY | ATP citrate lyase | -0.0262751 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0249087 |
| RPS21 | ribosomal protein S21 | -0.0246527 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0245787 |
| RPS15 | ribosomal protein S15 | -0.0236896 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0236438 |
| TMEM123 | transmembrane protein 123 | -0.0233963 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0231879 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0231303 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.02312 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0230645 |
| TAGLN2 | transgelin 2 | -0.0227994 |
| PFKP | phosphofructokinase, platelet | -0.0227189 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0225468 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0225426 |
| ANLN | anillin, actin binding protein | -0.0224822 |
| PFN1 | profilin 1 | -0.0224674 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0224658 |
