| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Everolimus perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Everolimus_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SAMD4A | sterile alpha motif domain containing 4A | 0.115606 |
| RPS12 | ribosomal protein S12 | 0.0908116 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0905565 |
| MT2A | metallothionein 2A | 0.0895119 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.087627 |
| KYNU | kynureninase | 0.0863155 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0862275 |
| EGR1 | early growth response 1 | 0.0775512 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0767138 |
| USP34 | ubiquitin specific peptidase 34 | 0.0764906 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0761787 |
| MYO1E | myosin IE | 0.0758085 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0713516 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0673931 |
| LAMC2 | laminin, gamma 2 | 0.0673404 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0671947 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0647094 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0638751 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0632888 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0626766 |
| RPL37A | ribosomal protein L37a | 0.0609251 |
| TCF12 | transcription factor 12 | 0.0608218 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0602965 |
| IGF2 | insulin-like growth factor 2 | 0.0601145 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0594215 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0591909 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0590981 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0584409 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0582293 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0574618 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0571791 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0570204 |
| DTNA | dystrobrevin, alpha | 0.0562612 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0542006 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0534966 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0531931 |
| RPLP1 | ribosomal protein, large, P1 | 0.0526765 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0524748 |
| OFD1 | oral-facial-digital syndrome 1 | 0.0521007 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0515419 |
| TPR | translocated promoter region, nuclear basket protein | 0.0511794 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0505562 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0504961 |
| CMIP | c-Maf inducing protein | 0.0502951 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0502913 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0500213 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0498835 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0495935 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0489778 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0482718 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0476217 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.047453 |
| RGS6 | regulator of G-protein signaling 6 | 0.047309 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0469955 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0466924 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0461644 |
| STC1 | stanniocalcin 1 | 0.0460804 |
| RPS17 | ribosomal protein S17 | 0.0458078 |
| ZNF207 | zinc finger protein 207 | 0.0457074 |
| RPS24 | ribosomal protein S24 | 0.0457021 |
| CDH13 | cadherin 13 | 0.0442704 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0442087 |
| EXOC6B | exocyst complex component 6B | 0.0436861 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0434981 |
| AATF | apoptosis antagonizing transcription factor | 0.0426481 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0425154 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0423842 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.04229 |
| GLCCI1 | glucocorticoid induced 1 | 0.0422417 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0420146 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0415994 |
| RPL5 | ribosomal protein L5 | 0.0414033 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0412806 |
| JAK2 | Janus kinase 2 | 0.0407944 |
| TPI1 | triosephosphate isomerase 1 | 0.0406776 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0404938 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0402376 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0401456 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0401216 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0400161 |
| RBM15 | RNA binding motif protein 15 | 0.0400068 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0399457 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0393875 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0390973 |
| RPLP2 | ribosomal protein, large, P2 | 0.0386238 |
| BRD2 | bromodomain containing 2 | 0.038254 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0381384 |
| MYO5B | myosin VB | 0.0374269 |
| VMP1 | vacuole membrane protein 1 | 0.037164 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.036525 |
| RPL28 | ribosomal protein L28 | 0.0364932 |
| PKM | pyruvate kinase, muscle | 0.0364507 |
| CDK6 | cyclin-dependent kinase 6 | 0.0363499 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0363209 |
| TNPO1 | transportin 1 | 0.0361591 |
| RPS27A | ribosomal protein S27a | 0.0361248 |
| ENO1 | enolase 1, (alpha) | 0.0354451 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0353452 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0347752 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0346678 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SMYD3 | SET and MYND domain containing 3 | -0.100939 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0921962 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0902698 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0796218 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0778138 |
| SVIL | supervillin | -0.074482 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0707772 |
| OSMR | oncostatin M receptor | -0.0699215 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0692125 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0664668 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.066305 |
| BPTF | bromodomain PHD finger transcription factor | -0.0641205 |
| FOXP1 | forkhead box P1 | -0.0632157 |
| FN1 | fibronectin 1 | -0.0628798 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0621517 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0598772 |
| CCNI | cyclin I | -0.0594651 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0592305 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0584939 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0571619 |
| EGFR | epidermal growth factor receptor | -0.056828 |
| ZNF638 | zinc finger protein 638 | -0.0562045 |
| LAMB3 | laminin, beta 3 | -0.0551514 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.054054 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0537993 |
| SPAG9 | sperm associated antigen 9 | -0.0537751 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0533693 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0529247 |
| OGA | O-GlcNAcase | -0.0512318 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0511986 |
| S100A10 | S100 calcium binding protein A10 | -0.0510949 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0508516 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0506096 |
| NUMB | numb homolog (Drosophila) | -0.0494672 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.049349 |
| CUX1 | cut-like homeobox 1 | -0.0486418 |
| ANXA2 | annexin A2 | -0.0483167 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0474146 |
| DENND1A | DENN/MADD domain containing 1A | -0.0463685 |
| ATRN | attractin | -0.0461561 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0460147 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0449267 |
| HOOK3 | hook microtubule-tethering protein 3 | -0.0443053 |
| LDHA | lactate dehydrogenase A | -0.0442484 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0439375 |
| UBC | ubiquitin C | -0.0438023 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0437027 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0434757 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0432524 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.043021 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0427098 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0424569 |
| FAT1 | FAT atypical cadherin 1 | -0.0423318 |
| POTEF | POTE ankyrin domain family, member F | -0.0416478 |
| SNX9 | sorting nexin 9 | -0.0410011 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0409173 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0405066 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0395074 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0389672 |
| PKP4 | plakophilin 4 | -0.0385607 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0385418 |
| VCAN | versican | -0.0384288 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0383017 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0382442 |
| OXSR1 | oxidative stress responsive 1 | -0.0380937 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0375762 |
| ARF1 | ADP-ribosylation factor 1 | -0.0369758 |
| TMCC3 | transmembrane and coiled-coil domain family 3 | -0.0369503 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0368505 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0367939 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0364179 |
| PRELID2 | PRELI domain containing 2 | -0.0362009 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0361191 |
| NEBL | nebulette | -0.0360878 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0360142 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0358375 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0357904 |
| RTN4 | reticulon 4 | -0.0357078 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0356214 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0354087 |
| MSI2 | musashi RNA-binding protein 2 | -0.0349663 |
| HLA-B | major histocompatibility complex, class I, B | -0.0342245 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0341236 |
| ATOSA | atos homolog A | -0.0339993 |
| TXNIP | thioredoxin interacting protein | -0.0339868 |
| RORA | RAR-related orphan receptor A | -0.0339264 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0338195 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0337374 |
| DIAPH1 | diaphanous-related formin 1 | -0.0337124 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.033619 |
| RIGI | RNA sensor RIG-I | -0.0336168 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0335538 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0334798 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0333615 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0328097 |
| STK17A | serine/threonine kinase 17a | -0.0326178 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0325394 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.032361 |
| ZNF292 | zinc finger protein 292 | -0.0322722 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0322094 |
