| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Everolimus perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Everolimus_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.219518 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.145295 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.124254 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0998084 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0923343 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0770787 |
| INTS6 | integrator complex subunit 6 | 0.0746772 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0651824 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.063956 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0635352 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0622656 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0617404 |
| RPS3 | ribosomal protein S3 | 0.0551156 |
| AEBP2 | AE binding protein 2 | 0.0548119 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0532029 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0521649 |
| HOMER1 | homer scaffolding protein 1 | 0.0514162 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0498114 |
| MCL1 | myeloid cell leukemia 1 | 0.0484646 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0450353 |
| RPS12 | ribosomal protein S12 | 0.0448747 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0447526 |
| VMP1 | vacuole membrane protein 1 | 0.0423326 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0423151 |
| PDLIM5 | PDZ and LIM domain 5 | 0.041155 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0411421 |
| PRELID2 | PRELI domain containing 2 | 0.0409573 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0407049 |
| MORF4L2 | mortality factor 4 like 2 | 0.0406845 |
| WWOX | WW domain containing oxidoreductase | 0.0405281 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0401825 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0399808 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0398184 |
| ANO6 | anoctamin 6 | 0.0386686 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.038312 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.0379609 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0379042 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.0375089 |
| RPS7 | ribosomal protein S7 | 0.0373417 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0372608 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0370557 |
| PRKCE | protein kinase C, epsilon | 0.0352885 |
| JMJD1C | jumonji domain containing 1C | 0.0352718 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.035241 |
| RPS8 | ribosomal protein S8 | 0.0351986 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.034621 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0340247 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0339996 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.033422 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0332902 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0331566 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0330683 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0325531 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0325089 |
| SIK3 | SIK family kinase 3 | 0.0315172 |
| BRD2 | bromodomain containing 2 | 0.0310288 |
| TOP1 | topoisomerase (DNA) I | 0.0310124 |
| TPM3 | tropomyosin 3 | 0.030881 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0301617 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0299141 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | 0.0296251 |
| HYOU1 | hypoxia up-regulated 1 | 0.0294905 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0288616 |
| ATP13A3 | ATPase type 13A3 | 0.0285388 |
| GOLGB1 | golgin B1 | 0.0280008 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0278389 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0276619 |
| DCAF10 | DDB1 and CUL4 associated factor 10 | 0.0276591 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0275503 |
| TRIM59 | tripartite motif containing 59 | 0.0275287 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0274608 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0274549 |
| CDK13 | cyclin-dependent kinase 13 | 0.0271528 |
| PHF3 | PHD finger protein 3 | 0.0268151 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.026737 |
| TPI1 | triosephosphate isomerase 1 | 0.0267308 |
| IPO7 | importin 7 | 0.0266212 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.026614 |
| YAP1 | Yes-associated protein 1 | 0.02592 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0257606 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0253254 |
| FERMT2 | fermitin family member 2 | 0.0252418 |
| DST | dystonin | 0.0249845 |
| NBEAL1 | neurobeachin-like 1 | 0.0249774 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0247911 |
| KMT5B | lysine methyltransferase 5B | 0.0247882 |
| SEPTIN2 | septin 2 | 0.0247172 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.024638 |
| VCL | vinculin | 0.0244311 |
| ENO1 | enolase 1, (alpha) | 0.0243891 |
| PCDH7 | protocadherin 7 | 0.0242589 |
| RAB10 | RAB10, member RAS oncogene family | 0.024141 |
| SET | SET nuclear proto-oncogene | 0.0240742 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0240662 |
| MACROD2 | MACRO domain containing 2 | 0.0235707 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.023547 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0235281 |
| R3HDM2 | R3H domain containing 2 | 0.0234983 |
| CRY1 | cryptochrome circadian clock 1 | 0.0233172 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0230798 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.242441 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.109095 |
| TXNRD1 | thioredoxin reductase 1 | -0.089892 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0600642 |
| TMSB10 | thymosin beta 10 | -0.0560843 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0558574 |
| RAD51B | RAD51 paralog B | -0.0554734 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.055434 |
| RPL35A | ribosomal protein L35a | -0.0546389 |
| PTMA | prothymosin, alpha | -0.053607 |
| UBC | ubiquitin C | -0.0501346 |
| RPS21 | ribosomal protein S21 | -0.0477186 |
| PHIP | pleckstrin homology domain interacting protein | -0.0462066 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0434492 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0431098 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0428201 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0426026 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.04212 |
| DIAPH3 | diaphanous-related formin 3 | -0.0420514 |
| RTN4 | reticulon 4 | -0.0420417 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0415045 |
| PFN1 | profilin 1 | -0.0414947 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0411668 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0393057 |
| CENPF | centromere protein F, 350/400kDa | -0.0388741 |
| AHNAK | AHNAK nucleoprotein | -0.0387099 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0384954 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0371284 |
| DEK | DEK proto-oncogene | -0.0363397 |
| XPO1 | exportin 1 | -0.03569 |
| POTEF | POTE ankyrin domain family, member F | -0.0354689 |
| MKI67 | marker of proliferation Ki-67 | -0.0350107 |
| GRAMD1B | GRAM domain containing 1B | -0.0344003 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0336566 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0327107 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0325427 |
| ACTG1 | actin gamma 1 | -0.0325376 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0324644 |
| H1-0 | H1.0 linker histone | -0.0323958 |
| WASF2 | WAS protein family, member 2 | -0.0317769 |
| IGF2 | insulin-like growth factor 2 | -0.0312879 |
| BBX | bobby sox homolog (Drosophila) | -0.0306161 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.030411 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0299631 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0297226 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0293735 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0292233 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0284096 |
| SIN3A | SIN3 transcription regulator family member A | -0.02836 |
| PGK1 | phosphoglycerate kinase 1 | -0.0283393 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.028291 |
| RPS15 | ribosomal protein S15 | -0.0281857 |
| RPS29 | ribosomal protein S29 | -0.0281535 |
| SMAD3 | SMAD family member 3 | -0.0278624 |
| RBM39 | RNA binding motif protein 39 | -0.0277262 |
| ZFR | zinc finger RNA binding protein | -0.0276071 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0273724 |
| TPX2 | TPX2, microtubule-associated | -0.0271578 |
| KIF18B | kinesin family member 18B | -0.0269925 |
| EGR1 | early growth response 1 | -0.0268496 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0267778 |
| RPS27A | ribosomal protein S27a | -0.0261242 |
| RPL8 | ribosomal protein L8 | -0.0259092 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.025869 |
| HMGA1 | high mobility group AT-hook 1 | -0.0258019 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.0255313 |
| ADAR | adenosine deaminase, RNA-specific | -0.0251763 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0250693 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0249039 |
| SRBD1 | S1 RNA binding domain 1 | -0.0248208 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | -0.024611 |
| CEP95 | centrosomal protein 95kDa | -0.0245214 |
| TPM2 | tropomyosin 2 (beta) | -0.0243757 |
| ANLN | anillin, actin binding protein | -0.0240161 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0234168 |
| TMEM165 | transmembrane protein 165 | -0.0234163 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0232583 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0230868 |
| RPS19 | ribosomal protein S19 | -0.0230749 |
| PRR11 | proline rich 11 | -0.0229871 |
| LDHB | lactate dehydrogenase B | -0.0229365 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0227255 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.0226762 |
| RPS6 | ribosomal protein S6 | -0.0226484 |
| SRPK1 | SRSF protein kinase 1 | -0.0226483 |
| MT1X | metallothionein 1X | -0.0225812 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.022505 |
| ANKRD36 | ankyrin repeat domain 36 | -0.0222741 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0220748 |
| RLIM | ring finger protein, LIM domain interacting | -0.0218705 |
| MELK | maternal embryonic leucine zipper kinase | -0.0217212 |
| GPSM2 | G-protein signaling modulator 2 | -0.0217129 |
| GLO1 | glyoxalase I | -0.0216293 |
| SRPK2 | SRSF protein kinase 2 | -0.0216099 |
| LATS2 | large tumor suppressor kinase 2 | -0.0215923 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0215035 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0213797 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0212858 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0211997 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.021063 |
