| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Everolimus perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Everolimus_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.19835 |
| FTL | ferritin, light polypeptide | 0.10496 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.101822 |
| RPS12 | ribosomal protein S12 | 0.087903 |
| RPS3 | ribosomal protein S3 | 0.0863744 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0767769 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0692714 |
| ENO1 | enolase 1, (alpha) | 0.0656637 |
| FHIT | fragile histidine triad | 0.0647506 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0606931 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.056972 |
| RPL37A | ribosomal protein L37a | 0.0557512 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0556315 |
| DTNA | dystrobrevin, alpha | 0.0554374 |
| RPL9 | ribosomal protein L9 | 0.0538833 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0527755 |
| RPS8 | ribosomal protein S8 | 0.05258 |
| RACK1 | receptor for activated C kinase 1 | 0.0503928 |
| RPS25 | ribosomal protein S25 | 0.0491732 |
| RPS17 | ribosomal protein S17 | 0.0491304 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0447984 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0437764 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0410201 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0405616 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0399045 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0393295 |
| HMGB2 | high mobility group box 2 | 0.0379788 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0378692 |
| MCL1 | myeloid cell leukemia 1 | 0.0373721 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0364415 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0362669 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0352589 |
| INTS6 | integrator complex subunit 6 | 0.0351353 |
| RPS2 | ribosomal protein S2 | 0.0345946 |
| LDHA | lactate dehydrogenase A | 0.0336895 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0335765 |
| RPS13 | ribosomal protein S13 | 0.0331115 |
| RAD51B | RAD51 paralog B | 0.0320845 |
| PKM | pyruvate kinase, muscle | 0.0318633 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0318623 |
| UPP1 | uridine phosphorylase 1 | 0.0314512 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0313029 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0312134 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0311581 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0310456 |
| EFNA5 | ephrin-A5 | 0.0297954 |
| VMP1 | vacuole membrane protein 1 | 0.0296092 |
| RPS27A | ribosomal protein S27a | 0.0294282 |
| RPS27 | ribosomal protein S27 | 0.0290508 |
| KIAA1217 | KIAA1217 | 0.0287992 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0287704 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0285557 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0283678 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.028355 |
| RPL31 | ribosomal protein L31 | 0.0280651 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0280578 |
| RAB10 | RAB10, member RAS oncogene family | 0.027994 |
| RPL37 | ribosomal protein L37 | 0.0278744 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0277746 |
| RPLP0 | ribosomal protein, large, P0 | 0.0275612 |
| RPL7A | ribosomal protein L7a | 0.0270134 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0269822 |
| TBCA | tubulin folding cofactor A | 0.0269152 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0261966 |
| RPS7 | ribosomal protein S7 | 0.0261012 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.025809 |
| RPL27 | ribosomal protein L27 | 0.0256088 |
| BRD2 | bromodomain containing 2 | 0.025608 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0255696 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0254452 |
| RPLP2 | ribosomal protein, large, P2 | 0.0252532 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.0250365 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.0250305 |
| RPL15 | ribosomal protein L15 | 0.0249781 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.024974 |
| PALLD | palladin, cytoskeletal associated protein | 0.0247604 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0244531 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0244011 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0243169 |
| CD109 | CD109 molecule | 0.0240978 |
| RPL7 | ribosomal protein L7 | 0.0240221 |
| HOMER1 | homer scaffolding protein 1 | 0.023933 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0236513 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0232512 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0229498 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 0.022914 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0227814 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0226425 |
| HDAC9 | histone deacetylase 9 | 0.0224616 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0223081 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.022193 |
| RPL13A | ribosomal protein L13a | 0.0220296 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | 0.021842 |
| HYOU1 | hypoxia up-regulated 1 | 0.0218357 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0217152 |
| RNF213 | ring finger protein 213 | 0.0216092 |
| RPL30 | ribosomal protein L30 | 0.021541 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0213515 |
| RPS16 | ribosomal protein S16 | 0.0213292 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0211105 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.208177 |
| ACTG1 | actin gamma 1 | -0.200081 |
| FN1 | fibronectin 1 | -0.178677 |
| NDRG1 | N-myc downstream regulated 1 | -0.15652 |
| TMSB10 | thymosin beta 10 | -0.131643 |
| TMSB4X | thymosin beta 4, X-linked | -0.109264 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0986613 |
| RPL35A | ribosomal protein L35a | -0.0979113 |
| LMO7 | LIM domain 7 | -0.0911002 |
| UBC | ubiquitin C | -0.0905512 |
| KRT7 | keratin 7, type II | -0.0854191 |
| S100A10 | S100 calcium binding protein A10 | -0.0802432 |
| CCND1 | cyclin D1 | -0.0749716 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0735064 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0734306 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0723508 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.06959 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0691956 |
| CD2AP | CD2-associated protein | -0.0668991 |
| LAMB3 | laminin, beta 3 | -0.0647035 |
| RPL34 | ribosomal protein L34 | -0.0645185 |
| FBXO32 | F-box protein 32 | -0.0607242 |
| POTEF | POTE ankyrin domain family, member F | -0.05949 |
| ASPH | aspartate beta-hydroxylase | -0.0569693 |
| LAMC2 | laminin, gamma 2 | -0.0558927 |
| HMGA1 | high mobility group AT-hook 1 | -0.0515691 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0496979 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0475112 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0471806 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0471547 |
| FAM3C | family with sequence similarity 3, member C | -0.0469381 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0466577 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0454978 |
| RBM39 | RNA binding motif protein 39 | -0.0452895 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0449859 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.044743 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0446029 |
| AHNAK | AHNAK nucleoprotein | -0.0445019 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0426269 |
| DSG2 | desmoglein 2 | -0.0415569 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0389953 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0387112 |
| TFG | TRK-fused gene | -0.0386917 |
| RPL8 | ribosomal protein L8 | -0.0384411 |
| TMEM263 | transmembrane protein 263 | -0.0379853 |
| PTMA | prothymosin, alpha | -0.0361056 |
| RRBP1 | ribosome binding protein 1 | -0.0360517 |
| PGK1 | phosphoglycerate kinase 1 | -0.0358796 |
| ARF1 | ADP-ribosylation factor 1 | -0.035246 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0347508 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0345657 |
| KRT18 | keratin 18, type I | -0.0344076 |
| SDC4 | syndecan 4 | -0.03434 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.034297 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0339566 |
| H1-0 | H1.0 linker histone | -0.0338457 |
| KRT8 | keratin 8, type II | -0.0336135 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0332903 |
| RPL32 | ribosomal protein L32 | -0.0325045 |
| CD63 | CD63 molecule | -0.0309692 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0299904 |
| KLHL24 | kelch-like family member 24 | -0.028748 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0282741 |
| TXNRD1 | thioredoxin reductase 1 | -0.0282495 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0277659 |
| DEK | DEK proto-oncogene | -0.0273584 |
| EPCAM | epithelial cell adhesion molecule | -0.0269979 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0266864 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0265664 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0263261 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0262768 |
| ZNF292 | zinc finger protein 292 | -0.0262749 |
| TMEM123 | transmembrane protein 123 | -0.0262642 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0262502 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0258922 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.025413 |
| RPS19 | ribosomal protein S19 | -0.0253582 |
| FAM162A | family with sequence similarity 162, member A | -0.0251271 |
| GNAS | GNAS complex locus | -0.0247765 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0247122 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0239345 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0239066 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0237489 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0236721 |
| USP3 | ubiquitin specific peptidase 3 | -0.0236228 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0232432 |
| YBX3 | Y box binding protein 3 | -0.023108 |
| MXD1 | MAX dimerization protein 1 | -0.0229622 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0227963 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0227696 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0226371 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.022128 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0220674 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0220285 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.0219597 |
| MORF4L1 | mortality factor 4 like 1 | -0.0219504 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0218639 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0217777 |
| ZNF217 | zinc finger protein 217 | -0.02168 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.02161 |
