| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Everolimus perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Everolimus_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.210501 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.122346 |
| LDHA | lactate dehydrogenase A | 0.121164 |
| KYNU | kynureninase | 0.101704 |
| RPS12 | ribosomal protein S12 | 0.0976382 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0943156 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0896861 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0891946 |
| VIM | vimentin | 0.0891358 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0863736 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0846081 |
| RPS8 | ribosomal protein S8 | 0.0787181 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0747248 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0696801 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0682096 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0654829 |
| CD109 | CD109 molecule | 0.0622398 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0609918 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0594317 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0593277 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0579543 |
| RPS3 | ribosomal protein S3 | 0.0570877 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0556224 |
| RACK1 | receptor for activated C kinase 1 | 0.0548681 |
| RPS2 | ribosomal protein S2 | 0.0543016 |
| RPL26 | ribosomal protein L26 | 0.0532991 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0530068 |
| RPS17 | ribosomal protein S17 | 0.052388 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0517009 |
| MYOF | myoferlin | 0.0516346 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0485499 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0484777 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0478741 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0478579 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0473733 |
| EZR | ezrin | 0.047312 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0471574 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0471417 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0466299 |
| GDA | guanine deaminase | 0.044792 |
| ENO1 | enolase 1, (alpha) | 0.0442875 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0436684 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0435123 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0416098 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0411887 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0411469 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0407963 |
| KRT19 | keratin 19, type I | 0.0407134 |
| RPS7 | ribosomal protein S7 | 0.0399714 |
| CLU | clusterin | 0.0397377 |
| MAP7 | microtubule-associated protein 7 | 0.0377065 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0368753 |
| RPL7 | ribosomal protein L7 | 0.0365774 |
| PKM | pyruvate kinase, muscle | 0.0363252 |
| RPL12 | ribosomal protein L12 | 0.0359184 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0356841 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0355498 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0355004 |
| FMNL2 | formin-like 2 | 0.0351189 |
| CTBP2 | C-terminal binding protein 2 | 0.0347182 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0346194 |
| SET | SET nuclear proto-oncogene | 0.0344542 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0343503 |
| DNER | delta/notch-like EGF repeat containing | 0.0335338 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0332321 |
| IRS2 | insulin receptor substrate 2 | 0.0331165 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0324808 |
| FTL | ferritin, light polypeptide | 0.03239 |
| TPI1 | triosephosphate isomerase 1 | 0.032257 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0320011 |
| COL5A2 | collagen, type V, alpha 2 | 0.0315651 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0314887 |
| RPS4X | ribosomal protein S4, X-linked | 0.0313629 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0308906 |
| SMAD2 | SMAD family member 2 | 0.0304551 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0304122 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0300712 |
| STC2 | stanniocalcin 2 | 0.0300017 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0296544 |
| GRAMD1B | GRAM domain containing 1B | 0.0296353 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0295744 |
| RPS27 | ribosomal protein S27 | 0.0294735 |
| MCL1 | myeloid cell leukemia 1 | 0.0294367 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0290775 |
| NTN4 | netrin 4 | 0.0290345 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0288155 |
| NFX1 | nuclear transcription factor, X-box binding 1 | 0.028762 |
| RPLP0 | ribosomal protein, large, P0 | 0.0286506 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.028506 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.028308 |
| RPL21 | ribosomal protein L21 | 0.0280501 |
| BMP6 | bone morphogenetic protein 6 | 0.0280322 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0277963 |
| RPL18 | ribosomal protein L18 | 0.027544 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0273003 |
| RASAL2 | RAS protein activator like 2 | 0.0272033 |
| ABLIM1 | actin binding LIM protein 1 | 0.0270172 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0264893 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0264294 |
| PCBP2 | poly(rC) binding protein 2 | 0.0263044 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.25249 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.224982 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.187092 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.125389 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.102106 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0912354 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0776987 |
| CANX | calnexin | -0.0755814 |
| ACTG1 | actin gamma 1 | -0.0735542 |
| RPL35A | ribosomal protein L35a | -0.0719558 |
| SMYD3 | SET and MYND domain containing 3 | -0.0677944 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0635125 |
| CDH13 | cadherin 13 | -0.0612061 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0584022 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0564671 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0538086 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0518549 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0512455 |
| PTMA | prothymosin, alpha | -0.0494692 |
| TMSB10 | thymosin beta 10 | -0.0487492 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0455416 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0452626 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0442757 |
| VCL | vinculin | -0.0423632 |
| AHNAK | AHNAK nucleoprotein | -0.0423248 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0422674 |
| UBC | ubiquitin C | -0.0420513 |
| TMSB4X | thymosin beta 4, X-linked | -0.0410156 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0403118 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0394785 |
| NCKAP5 | NCK-associated protein 5 | -0.0373815 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0370662 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0370406 |
| STC1 | stanniocalcin 1 | -0.0367846 |
| RPL34 | ribosomal protein L34 | -0.0366181 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0361395 |
| HLA-B | major histocompatibility complex, class I, B | -0.0358917 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0344975 |
| RBM39 | RNA binding motif protein 39 | -0.0338031 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0336354 |
| RPL38 | ribosomal protein L38 | -0.0331613 |
| RPS21 | ribosomal protein S21 | -0.032812 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0324744 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.031333 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.029127 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0279781 |
| RPS29 | ribosomal protein S29 | -0.0269168 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0264347 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0261368 |
| STEAP1B | STEAP family member 1B | -0.025866 |
| TBXT | T-box transcription factor T | -0.0257383 |
| ESM1 | endothelial cell-specific molecule 1 | -0.0254402 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0253312 |
| NRCAM | neuronal cell adhesion molecule | -0.0252641 |
| PGK1 | phosphoglycerate kinase 1 | -0.0247708 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | -0.0239705 |
| PCBP3 | poly(rC) binding protein 3 | -0.0238424 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.023535 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0227817 |
| PTGR1 | prostaglandin reductase 1 | -0.0226381 |
| GNAS | GNAS complex locus | -0.0225649 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0225595 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0223892 |
| S100A10 | S100 calcium binding protein A10 | -0.0220893 |
| KIAA0825 | KIAA0825 | -0.021977 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0217941 |
| CALR | calreticulin | -0.0215155 |
| CD63 | CD63 molecule | -0.0215106 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0213811 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.02135 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0211951 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0211792 |
| SRGN | serglycin | -0.0209868 |
| CDK12 | cyclin-dependent kinase 12 | -0.0209818 |
| IER3 | immediate early response 3 | -0.0208931 |
| RPL6 | ribosomal protein L6 | -0.0207269 |
| RPS23 | ribosomal protein S23 | -0.0202656 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0201655 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0199401 |
| LAMB1 | laminin, beta 1 | -0.0198669 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0198383 |
| AGR2 | anterior gradient 2 | -0.019812 |
| FUS | FUS RNA binding protein | -0.0196826 |
| RPS11 | ribosomal protein S11 | -0.0196174 |
| TPM4 | tropomyosin 4 | -0.0195724 |
| RRBP1 | ribosome binding protein 1 | -0.0195094 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0195027 |
| ARF1 | ADP-ribosylation factor 1 | -0.0194135 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0192895 |
| RPS24 | ribosomal protein S24 | -0.019224 |
| CTSL | cathepsin L | -0.0192143 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0184001 |
| RTN1 | reticulon 1 | -0.0183105 |
| RPS15 | ribosomal protein S15 | -0.0182654 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0182178 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0182118 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0181404 |
| FBXO11 | F-box protein 11 | -0.01811 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0180737 |
| CADM2 | cell adhesion molecule 2 | -0.0179781 |
