| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Everolimus perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Everolimus_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.17735 |
| CD44 | CD44 molecule (Indian blood group) | 0.140874 |
| PKM | pyruvate kinase, muscle | 0.108036 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.106833 |
| RPS12 | ribosomal protein S12 | 0.0995445 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0939005 |
| RAD51B | RAD51 paralog B | 0.0896138 |
| SPAG9 | sperm associated antigen 9 | 0.0843987 |
| MYO10 | myosin X | 0.0842826 |
| PTEN | phosphatase and tensin homolog | 0.0812806 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0785842 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0776338 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0765473 |
| USP34 | ubiquitin specific peptidase 34 | 0.0748147 |
| RPS8 | ribosomal protein S8 | 0.0710302 |
| RPS6 | ribosomal protein S6 | 0.0707514 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0706316 |
| MT2A | metallothionein 2A | 0.0704849 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0685634 |
| FBXO11 | F-box protein 11 | 0.066748 |
| EGFR | epidermal growth factor receptor | 0.0662852 |
| HMGA2 | high mobility group AT-hook 2 | 0.0643343 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.064285 |
| DENND1A | DENN/MADD domain containing 1A | 0.0637985 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0630088 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0614455 |
| ASPH | aspartate beta-hydroxylase | 0.0606999 |
| TPM4 | tropomyosin 4 | 0.0602518 |
| RPL19 | ribosomal protein L19 | 0.0597521 |
| GOLGB1 | golgin B1 | 0.0594632 |
| ENO1 | enolase 1, (alpha) | 0.0590723 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0590313 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0588686 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0585587 |
| SMAD3 | SMAD family member 3 | 0.058259 |
| SQSTM1 | sequestosome 1 | 0.058114 |
| STC1 | stanniocalcin 1 | 0.0565971 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0562458 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0557568 |
| SLTM | SAFB-like, transcription modulator | 0.0556713 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0554331 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0550599 |
| EXT1 | exostosin glycosyltransferase 1 | 0.054942 |
| ANXA2 | annexin A2 | 0.054369 |
| LDHA | lactate dehydrogenase A | 0.0540876 |
| FRMD5 | FERM domain containing 5 | 0.0540605 |
| CDCP1 | CUB domain containing protein 1 | 0.0534455 |
| RPL26 | ribosomal protein L26 | 0.052648 |
| HLA-B | major histocompatibility complex, class I, B | 0.0522648 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0518642 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0516703 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0515627 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0514472 |
| ERBIN | erbb2 interacting protein | 0.0513425 |
| INHBA | inhibin, beta A | 0.0513348 |
| CLTC | clathrin, heavy chain (Hc) | 0.0509027 |
| MKI67 | marker of proliferation Ki-67 | 0.0508203 |
| KRT8 | keratin 8, type II | 0.0499679 |
| RPL37A | ribosomal protein L37a | 0.0492998 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0490443 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0489766 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0487933 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0487898 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0484178 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0476648 |
| PGK1 | phosphoglycerate kinase 1 | 0.0473798 |
| RPS5 | ribosomal protein S5 | 0.0472389 |
| RPL23 | ribosomal protein L23 | 0.0468508 |
| RPS2 | ribosomal protein S2 | 0.0463696 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0457131 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0456862 |
| RPS3 | ribosomal protein S3 | 0.0451535 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0449882 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0448509 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0445278 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0444606 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0444242 |
| CTBP2 | C-terminal binding protein 2 | 0.0437064 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0424283 |
| BRD2 | bromodomain containing 2 | 0.0423995 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.042068 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0405551 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0404898 |
| LAMA4 | laminin, alpha 4 | 0.0404236 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0402433 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0401243 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0400612 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0397632 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0397561 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0391156 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0389815 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0388444 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0385957 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0385173 |
| RPL9 | ribosomal protein L9 | 0.0381476 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0380535 |
| TPI1 | triosephosphate isomerase 1 | 0.0372689 |
| EZR | ezrin | 0.0369478 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0367396 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0362416 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.138938 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.101986 |
| VIM | vimentin | -0.0981188 |
| EFNA5 | ephrin-A5 | -0.0980959 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0968026 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.093018 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.090102 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0890175 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.083174 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0803634 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0785291 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0766557 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0763014 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0738627 |
| VMP1 | vacuole membrane protein 1 | -0.0738141 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0723781 |
| STK24 | serine/threonine kinase 24 | -0.0658776 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0653505 |
| RORA | RAR-related orphan receptor A | -0.0648366 |
| JMJD1C | jumonji domain containing 1C | -0.064006 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0590668 |
| MATR3 | matrin 3 | -0.0575621 |
| RNF145 | ring finger protein 145 | -0.0572554 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0567477 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0559722 |
| POTEF | POTE ankyrin domain family, member F | -0.0544186 |
| FMN1 | formin 1 | -0.0543963 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0537803 |
| PARD3 | par-3 family cell polarity regulator | -0.0537577 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0534288 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0513277 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0510592 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0507553 |
| DIAPH2 | diaphanous-related formin 2 | -0.0507164 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0504374 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0504368 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0504133 |
| PRKCA | protein kinase C, alpha | -0.0502216 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0495601 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0493246 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0491516 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0489672 |
| LMNA | lamin A/C | -0.0484909 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0484564 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0479571 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0478666 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0478188 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0476317 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0466686 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0463396 |
| RPS23 | ribosomal protein S23 | -0.0459454 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0455014 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0454255 |
| RTN4 | reticulon 4 | -0.045297 |
| ETNK1 | ethanolamine kinase 1 | -0.044921 |
| RBM39 | RNA binding motif protein 39 | -0.0447194 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0428335 |
| ZNF292 | zinc finger protein 292 | -0.0423396 |
| YBX3 | Y box binding protein 3 | -0.0416151 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0416079 |
| FUS | FUS RNA binding protein | -0.041485 |
| FTL | ferritin, light polypeptide | -0.0409366 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0404259 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0402136 |
| CALR | calreticulin | -0.0400129 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0397692 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0395562 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0390712 |
| RLF | rearranged L-myc fusion | -0.0381946 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.0380427 |
| SPATA13 | spermatogenesis associated 13 | -0.0379962 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0379552 |
| FOXJ3 | forkhead box J3 | -0.0379394 |
| PDE10A | phosphodiesterase 10A | -0.0375465 |
| WASF2 | WAS protein family, member 2 | -0.0371246 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0367253 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0366571 |
| RPLP2 | ribosomal protein, large, P2 | -0.0365981 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0363415 |
| TXNRD1 | thioredoxin reductase 1 | -0.035882 |
| FLNB | filamin B, beta | -0.0356629 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0355408 |
| CDH13 | cadherin 13 | -0.0354512 |
| PDS5B | PDS5 cohesin associated factor B | -0.034717 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0344187 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0342474 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0340349 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0340038 |
| MED13L | mediator complex subunit 13-like | -0.0339984 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0337894 |
| RPLP1 | ribosomal protein, large, P1 | -0.0337607 |
| RPL4 | ribosomal protein L4 | -0.0331475 |
| AHNAK | AHNAK nucleoprotein | -0.0331333 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0328758 |
| HELZ | helicase with zinc finger | -0.0328271 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0327314 |
| COL1A1 | collagen, type I, alpha 1 | -0.0326057 |
| CANX | calnexin | -0.0325569 |
| SNX9 | sorting nexin 9 | -0.0325187 |
| VCL | vinculin | -0.0323831 |
