| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Everolimus perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Everolimus_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | 0.140238 |
| HDAC9 | histone deacetylase 9 | 0.108488 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0941248 |
| SRP54 | signal recognition particle 54kDa | 0.0831521 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0765712 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0731075 |
| RPS8 | ribosomal protein S8 | 0.0712797 |
| JMJD1C | jumonji domain containing 1C | 0.0676568 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0662936 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0645462 |
| CADM2 | cell adhesion molecule 2 | 0.0597219 |
| FNDC3A | fibronectin type III domain containing 3A | 0.058395 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0554512 |
| RPS16 | ribosomal protein S16 | 0.0528688 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0516023 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0501217 |
| B2M | beta-2-microglobulin | 0.0492327 |
| SNX3 | sorting nexin 3 | 0.0486089 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0484495 |
| RPL37A | ribosomal protein L37a | 0.0477459 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0476516 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0472695 |
| KIF21A | kinesin family member 21A | 0.0466681 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0460844 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0450256 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0449244 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0447638 |
| RPS12 | ribosomal protein S12 | 0.0428055 |
| CDC73 | cell division cycle 73 | 0.0407843 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0405349 |
| SNX6 | sorting nexin 6 | 0.0402709 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0402361 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0396891 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0393835 |
| RPL26 | ribosomal protein L26 | 0.0389682 |
| PCDH18 | protocadherin 18 | 0.0385789 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0384811 |
| RPS3 | ribosomal protein S3 | 0.0369947 |
| BRD2 | bromodomain containing 2 | 0.0368954 |
| FOXO1 | forkhead box O1 | 0.0361019 |
| NTM | neurotrimin | 0.0358536 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0358535 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0355992 |
| ITSN2 | intersectin 2 | 0.0351321 |
| HYOU1 | hypoxia up-regulated 1 | 0.0349286 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0348232 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.03454 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0345164 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0344619 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0342101 |
| RPL23 | ribosomal protein L23 | 0.0341531 |
| FMNL2 | formin-like 2 | 0.0336151 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0333728 |
| PEG10 | paternally expressed 10 | 0.0330843 |
| RPS6 | ribosomal protein S6 | 0.0328233 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0319946 |
| MYO6 | myosin VI | 0.0315913 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0315803 |
| PLPP1 | phospholipid phosphatase 1 | 0.0315101 |
| VRK2 | vaccinia related kinase 2 | 0.0314848 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0314122 |
| RPL9 | ribosomal protein L9 | 0.0307357 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0306281 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0305207 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0304012 |
| WWC2 | WW and C2 domain containing 2 | 0.0296464 |
| NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 0.0295054 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.029196 |
| LPIN2 | lipin 2 | 0.0291691 |
| PRTG | protogenin | 0.0291084 |
| ERBIN | erbb2 interacting protein | 0.0290726 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0286072 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0284551 |
| PRKD1 | protein kinase D1 | 0.0283564 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0282604 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0282058 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0281544 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0281222 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0280066 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0279706 |
| RPS2 | ribosomal protein S2 | 0.0279412 |
| NSD1 | nuclear receptor binding SET domain protein 1 | 0.0277789 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0277389 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0275248 |
| RPS27 | ribosomal protein S27 | 0.0274925 |
| SETD5 | SET domain containing 5 | 0.0272797 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.027234 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0271623 |
| TMEM87A | transmembrane protein 87A | 0.0270608 |
| MCL1 | myeloid cell leukemia 1 | 0.0270275 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.0268567 |
| RANBP9 | RAN binding protein 9 | 0.0268531 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0267086 |
| TNRC18 | trinucleotide repeat containing 18 | 0.026591 |
| TAOK3 | TAO kinase 3 | 0.0264973 |
| RPL12 | ribosomal protein L12 | 0.0264804 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0264186 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 | 0.0263662 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0263459 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0262335 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.125417 |
| ACTG1 | actin gamma 1 | -0.124882 |
| DST | dystonin | -0.107635 |
| TENM3 | teneurin transmembrane protein 3 | -0.0901077 |
| THBS1 | thrombospondin 1 | -0.0899681 |
| AHNAK | AHNAK nucleoprotein | -0.0824871 |
| COL5A2 | collagen, type V, alpha 2 | -0.0806521 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0783682 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0681533 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0669432 |
| H1-0 | H1.0 linker histone | -0.0576202 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0572454 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0566874 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0560337 |
| EMP1 | epithelial membrane protein 1 | -0.0539342 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0530034 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.052701 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0491255 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0489611 |
| TMSB4X | thymosin beta 4, X-linked | -0.0478505 |
| TPX2 | TPX2, microtubule-associated | -0.0477613 |
| MKI67 | marker of proliferation Ki-67 | -0.0472914 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0471155 |
| KIF4A | kinesin family member 4A | -0.0460261 |
| CCN2 | cellular communication network factor 2 | -0.045762 |
| DEK | DEK proto-oncogene | -0.0452972 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -0.0447366 |
| GPC3 | glypican 3 | -0.0432548 |
| CENPE | centromere protein E, 312kDa | -0.0425724 |
| PGK1 | phosphoglycerate kinase 1 | -0.042063 |
| CENPF | centromere protein F, 350/400kDa | -0.0414339 |
| PRELID2 | PRELI domain containing 2 | -0.0404005 |
| COL1A2 | collagen, type I, alpha 2 | -0.0403157 |
| HMGB1 | high mobility group box 1 | -0.0401542 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0398989 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.03956 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | -0.0393012 |
| BPTF | bromodomain PHD finger transcription factor | -0.0389875 |
| SGO2 | shugoshin 2 | -0.038704 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0385154 |
| TXNRD1 | thioredoxin reductase 1 | -0.0384319 |
| RPS21 | ribosomal protein S21 | -0.0377539 |
| PRR11 | proline rich 11 | -0.0371694 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0368921 |
| RTN4 | reticulon 4 | -0.0363913 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.0362253 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0360766 |
| HBP1 | HMG-box transcription factor 1 | -0.0360457 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0360259 |
| TTK | TTK protein kinase | -0.0359566 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0349446 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0343235 |
| CUL3 | cullin 3 | -0.0340364 |
| ZNF385D | zinc finger protein 385D | -0.0337579 |
| UBC | ubiquitin C | -0.033721 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0332539 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.033238 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0332209 |
| FOXP2 | forkhead box P2 | -0.0331539 |
| PCDH7 | protocadherin 7 | -0.0330777 |
| RBM39 | RNA binding motif protein 39 | -0.0323306 |
| RAI1 | retinoic acid induced 1 | -0.0322451 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0315579 |
| HSPA4 | heat shock 70kDa protein 4 | -0.0307575 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0307328 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0306724 |
| SIK2 | salt-inducible kinase 2 | -0.0304049 |
| VCL | vinculin | -0.0302993 |
| CDK12 | cyclin-dependent kinase 12 | -0.0301175 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0300071 |
| DIAPH3 | diaphanous-related formin 3 | -0.0297604 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.0297359 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | -0.0297259 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | -0.0296721 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0295756 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0292469 |
| GLI3 | GLI family zinc finger 3 | -0.0291152 |
| COL3A1 | collagen, type III, alpha 1 | -0.0288565 |
| SLC30A8 | solute carrier family 30 (zinc transporter), member 8 | -0.0287787 |
| WDR70 | WD repeat domain 70 | -0.0286784 |
| RPL35A | ribosomal protein L35a | -0.0283068 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0280533 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0279638 |
| PLS3 | plastin 3 | -0.0279524 |
| TPM4 | tropomyosin 4 | -0.0279293 |
| HMGA2 | high mobility group AT-hook 2 | -0.027924 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0278212 |
| YBX1 | Y box binding protein 1 | -0.0277239 |
| PARP1 | poly (ADP-ribose) polymerase 1 | -0.027669 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0276585 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0276371 |
| EXOC4 | exocyst complex component 4 | -0.0274807 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0274683 |
| GOLGB1 | golgin B1 | -0.0273694 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0273324 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.0272918 |
| ABI2 | abl-interactor 2 | -0.0267582 |
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | -0.0266161 |
| EXOC2 | exocyst complex component 2 | -0.026599 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0265386 |
