| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Everolimus perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Everolimus_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.217121 |
| PKM | pyruvate kinase, muscle | 0.0942936 |
| ENO1 | enolase 1, (alpha) | 0.0850274 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0803939 |
| HDAC9 | histone deacetylase 9 | 0.0744064 |
| RPS8 | ribosomal protein S8 | 0.073937 |
| RPS12 | ribosomal protein S12 | 0.071187 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0612919 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.058469 |
| RACK1 | receptor for activated C kinase 1 | 0.0570977 |
| DUSP4 | dual specificity phosphatase 4 | 0.0491265 |
| RPS3 | ribosomal protein S3 | 0.0461774 |
| RPL12 | ribosomal protein L12 | 0.0461555 |
| RPL7 | ribosomal protein L7 | 0.0430734 |
| ZNF608 | zinc finger protein 608 | 0.0424752 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0421065 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.041672 |
| RPLP0 | ribosomal protein, large, P0 | 0.0414153 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0404356 |
| RPL26 | ribosomal protein L26 | 0.0392187 |
| LDHA | lactate dehydrogenase A | 0.0385953 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0379731 |
| RPS2 | ribosomal protein S2 | 0.0365616 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0342026 |
| RPL13A | ribosomal protein L13a | 0.0331063 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0316488 |
| SET | SET nuclear proto-oncogene | 0.0313349 |
| RPS17 | ribosomal protein S17 | 0.030883 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.030815 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0307376 |
| TUBA1B | tubulin, alpha 1b | 0.0305282 |
| RPL18 | ribosomal protein L18 | 0.0304789 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0304024 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0296402 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0288354 |
| TRIOBP | TRIO and F-actin binding protein | 0.0284613 |
| MKI67 | marker of proliferation Ki-67 | 0.0282532 |
| RPS7 | ribosomal protein S7 | 0.0280666 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0278747 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0275331 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0270799 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0270233 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0270066 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.0268241 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0266821 |
| PLK2 | polo-like kinase 2 | 0.0265996 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0261289 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0249698 |
| ANXA1 | annexin A1 | 0.0247384 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0246295 |
| MATR3 | matrin 3 | 0.0244593 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0243565 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.024286 |
| TPI1 | triosephosphate isomerase 1 | 0.0240667 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0238251 |
| UBE3A | ubiquitin protein ligase E3A | 0.0230814 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0223764 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0221714 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.0219309 |
| GPHN | gephyrin | 0.0212496 |
| JUN | jun proto-oncogene | 0.0209405 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0208445 |
| KLF6 | Kruppel-like factor 6 | 0.0205212 |
| MACROD2 | MACRO domain containing 2 | 0.0204469 |
| SERINC1 | serine incorporator 1 | 0.0203871 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) | 0.020169 |
| KLF2 | Kruppel-like factor 2 | 0.0200802 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0200662 |
| ITSN2 | intersectin 2 | 0.0198975 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0196529 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0194527 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0193421 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0190768 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0188593 |
| RPL39 | ribosomal protein L39 | 0.0188055 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0187257 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0185433 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0184369 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0183122 |
| RPS27 | ribosomal protein S27 | 0.0182278 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0182117 |
| RBBP8 | retinoblastoma binding protein 8 | 0.0181457 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.017871 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme | 0.0177558 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.0176885 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0176713 |
| LRRC7 | leucine rich repeat containing 7 | 0.0175175 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.0174987 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0172499 |
| PARD3B | par-3 family cell polarity regulator beta | 0.017212 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0170596 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.0168235 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0167884 |
| PUS7 | pseudouridylate synthase 7 (putative) | 0.0167626 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0167567 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0166907 |
| RPL4 | ribosomal protein L4 | 0.0166113 |
| CEP350 | centrosomal protein 350kDa | 0.0164993 |
| SCFD1 | sec1 family domain containing 1 | 0.0164349 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0160307 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.271406 |
| PTMA | prothymosin, alpha | -0.140137 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.136925 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.104612 |
| RPL35A | ribosomal protein L35a | -0.098057 |
| VCL | vinculin | -0.0898776 |
| RBM39 | RNA binding motif protein 39 | -0.0894937 |
| ACTG1 | actin gamma 1 | -0.08662 |
| BMP10 | bone morphogenetic protein 10 | -0.086342 |
| FOXP1 | forkhead box P1 | -0.0859226 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0852071 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0828871 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0791023 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0741336 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0688989 |
| EVI5 | ecotropic viral integration site 5 | -0.0629021 |
| RPS19 | ribosomal protein S19 | -0.060314 |
| NBEA | neurobeachin | -0.0586762 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0585985 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0559552 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.05594 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0538933 |
| NFIA | nuclear factor I/A | -0.053817 |
| POTEF | POTE ankyrin domain family, member F | -0.0535273 |
| RPS23 | ribosomal protein S23 | -0.052336 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0517379 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0507331 |
| PFN1 | profilin 1 | -0.0488344 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0473135 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.046798 |
| TMSB10 | thymosin beta 10 | -0.0442288 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0439418 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0438832 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0436038 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0435996 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0424171 |
| TMSB4X | thymosin beta 4, X-linked | -0.0421273 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0409972 |
| ARF4 | ADP-ribosylation factor 4 | -0.0406171 |
| RPS29 | ribosomal protein S29 | -0.0402162 |
| EGFR | epidermal growth factor receptor | -0.040211 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0394037 |
| TJP1 | tight junction protein 1 | -0.0391396 |
| HLA-B | major histocompatibility complex, class I, B | -0.0390877 |
| NEBL | nebulette | -0.0389595 |
| FLNB | filamin B, beta | -0.0378188 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.037243 |
| RPL34 | ribosomal protein L34 | -0.0369492 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.03649 |
| AHNAK | AHNAK nucleoprotein | -0.0362823 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0361657 |
| PARD3 | par-3 family cell polarity regulator | -0.0359218 |
| GNAS | GNAS complex locus | -0.0356604 |
| VIM | vimentin | -0.0354043 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0354005 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0353875 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.035118 |
| TBC1D22A | TBC1 domain family, member 22A | -0.034868 |
| FBXO11 | F-box protein 11 | -0.0344065 |
| IGF1R | insulin-like growth factor 1 receptor | -0.034285 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0340785 |
| S100A10 | S100 calcium binding protein A10 | -0.0339991 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0339768 |
| UBC | ubiquitin C | -0.0338486 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.03379 |
| QKI | QKI, KH domain containing, RNA binding | -0.0332844 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0330591 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0326245 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0322689 |
| TFG | TRK-fused gene | -0.0318023 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0316667 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -0.0313785 |
| FUS | FUS RNA binding protein | -0.031321 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0311645 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0310517 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0309152 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.030875 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0307841 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0302429 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0298224 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0298117 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0298017 |
| NF1 | neurofibromin 1 | -0.0294549 |
| EFNA5 | ephrin-A5 | -0.0293259 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0291894 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0286887 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.028525 |
| NBAS | neuroblastoma amplified sequence | -0.0283863 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0283338 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0280318 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0280097 |
| EXOC6B | exocyst complex component 6B | -0.0279541 |
| OGA | O-GlcNAcase | -0.0278477 |
| PCBP2 | poly(rC) binding protein 2 | -0.0278332 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0277843 |
| FOXJ3 | forkhead box J3 | -0.0276277 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.0275902 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0275722 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0275529 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0273594 |
