| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Everolimus perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Everolimus_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.158911 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.11511 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0889154 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0772691 |
| LDHA | lactate dehydrogenase A | 0.071122 |
| RUNX1 | runt-related transcription factor 1 | 0.0671435 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0657501 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.063883 |
| ENO1 | enolase 1, (alpha) | 0.0618098 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.060068 |
| HMGA2 | high mobility group AT-hook 2 | 0.059569 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0564826 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0540455 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0537153 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0534996 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0521059 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0498378 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.049074 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0478008 |
| FNDC3B | fibronectin type III domain containing 3B | 0.047505 |
| ECE1 | endothelin converting enzyme 1 | 0.0439958 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.043969 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0432907 |
| COL6A2 | collagen, type VI, alpha 2 | 0.043251 |
| RNF145 | ring finger protein 145 | 0.0430901 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0429397 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.04287 |
| HYOU1 | hypoxia up-regulated 1 | 0.0425276 |
| RPS8 | ribosomal protein S8 | 0.0425248 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0423555 |
| PRELID2 | PRELI domain containing 2 | 0.0422886 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.04228 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0414695 |
| FTL | ferritin, light polypeptide | 0.0413146 |
| RPL37A | ribosomal protein L37a | 0.041042 |
| ATP13A3 | ATPase type 13A3 | 0.0408682 |
| VEGFA | vascular endothelial growth factor A | 0.0405069 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0404378 |
| CALD1 | caldesmon 1 | 0.0399875 |
| ZNF395 | zinc finger protein 395 | 0.0392701 |
| GOLGA4 | golgin A4 | 0.039209 |
| KYNU | kynureninase | 0.0384961 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0382662 |
| SNX13 | sorting nexin 13 | 0.037902 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0377366 |
| PKM | pyruvate kinase, muscle | 0.0376948 |
| FAM13A | family with sequence similarity 13, member A | 0.0375883 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0374875 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0374139 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0372989 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0368074 |
| RNF24 | ring finger protein 24 | 0.0367833 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0366297 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0362915 |
| IL6ST | interleukin 6 signal transducer | 0.0360246 |
| STC1 | stanniocalcin 1 | 0.0357911 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0355216 |
| VIM | vimentin | 0.0351623 |
| CADM1 | cell adhesion molecule 1 | 0.0351519 |
| RPS6 | ribosomal protein S6 | 0.0350385 |
| RYBP | RING1 and YY1 binding protein | 0.0348043 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0337489 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0325079 |
| B2M | beta-2-microglobulin | 0.0323353 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0319625 |
| MMP2 | matrix metallopeptidase 2 | 0.0316956 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0315932 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0315343 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0307146 |
| GOLGB1 | golgin B1 | 0.0306452 |
| RACK1 | receptor for activated C kinase 1 | 0.030166 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.0300358 |
| RPL26 | ribosomal protein L26 | 0.0299613 |
| BBX | bobby sox homolog (Drosophila) | 0.0297782 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0296983 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.029642 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0295916 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | 0.0294964 |
| RPL23 | ribosomal protein L23 | 0.029282 |
| VMP1 | vacuole membrane protein 1 | 0.0292158 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0291658 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0291016 |
| SYNJ2 | synaptojanin 2 | 0.0288952 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0288445 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0286624 |
| MYLK | myosin light chain kinase | 0.0285586 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 0.0285539 |
| PGM3 | phosphoglucomutase 3 | 0.0284487 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0282775 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0282156 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0279308 |
| RIN2 | Ras and Rab interactor 2 | 0.0277726 |
| RPS3 | ribosomal protein S3 | 0.0274148 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0272861 |
| RPS17 | ribosomal protein S17 | 0.027259 |
| RPL5 | ribosomal protein L5 | 0.0268415 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0265923 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.026585 |
| NKTR | natural killer cell triggering receptor | 0.0264971 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0261976 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.410469 |
| COL6A3 | collagen, type VI, alpha 3 | -0.164486 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.113487 |
| COL1A1 | collagen, type I, alpha 1 | -0.110599 |
| COL1A2 | collagen, type I, alpha 2 | -0.103898 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.103153 |
| FN1 | fibronectin 1 | -0.0976586 |
| TMSB10 | thymosin beta 10 | -0.0687617 |
| UBC | ubiquitin C | -0.0683606 |
| CDH13 | cadherin 13 | -0.0606526 |
| POTEF | POTE ankyrin domain family, member F | -0.0570309 |
| AHNAK | AHNAK nucleoprotein | -0.0555555 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0529581 |
| LOXL2 | lysyl oxidase-like 2 | -0.0516632 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0515751 |
| SDC4 | syndecan 4 | -0.0509677 |
| HLA-B | major histocompatibility complex, class I, B | -0.0508178 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0496076 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0491792 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.047501 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0467475 |
| VCL | vinculin | -0.0464226 |
| HLA-C | major histocompatibility complex, class I, C | -0.0457123 |
| PTMA | prothymosin, alpha | -0.0456874 |
| OGA | O-GlcNAcase | -0.0448893 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0441716 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.042951 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.040419 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0403189 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0386166 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0376808 |
| LOX | lysyl oxidase | -0.0372687 |
| CANX | calnexin | -0.036246 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0347616 |
| MYOF | myoferlin | -0.0346976 |
| S100A10 | S100 calcium binding protein A10 | -0.0345017 |
| PDE10A | phosphodiesterase 10A | -0.0340445 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0335916 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0322902 |
| ZNF217 | zinc finger protein 217 | -0.0310426 |
| COL5A2 | collagen, type V, alpha 2 | -0.0309894 |
| NAV1 | neuron navigator 1 | -0.0307692 |
| COL3A1 | collagen, type III, alpha 1 | -0.030498 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0303727 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.029314 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0289513 |
| CENPF | centromere protein F, 350/400kDa | -0.0288686 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0282693 |
| TFG | TRK-fused gene | -0.0281505 |
| TPX2 | TPX2, microtubule-associated | -0.0281492 |
| HDAC8 | histone deacetylase 8 | -0.0281147 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0280468 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0278278 |
| RBM39 | RNA binding motif protein 39 | -0.0277505 |
| NABP1 | nucleic acid binding protein 1 | -0.0272741 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0271692 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0269678 |
| EMP1 | epithelial membrane protein 1 | -0.0267843 |
| ARF1 | ADP-ribosylation factor 1 | -0.02646 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0261627 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0260732 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0260411 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0259294 |
| MT1X | metallothionein 1X | -0.0249235 |
| CCNI | cyclin I | -0.0247945 |
| RAD51B | RAD51 paralog B | -0.0247198 |
| HBP1 | HMG-box transcription factor 1 | -0.0243202 |
| SEC24D | SEC24 family member D | -0.0243025 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0231289 |
| TUBB | tubulin, beta class I | -0.0231233 |
| ACTG1 | actin gamma 1 | -0.0230272 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0228562 |
| RHEB | Ras homolog enriched in brain | -0.0227651 |
| CST3 | cystatin C | -0.0226777 |
| GLG1 | golgi glycoprotein 1 | -0.0226519 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0224305 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.0224175 |
| RHOA | ras homolog family member A | -0.0220263 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0218229 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0217886 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0216677 |
| SUCO | SUN domain containing ossification factor | -0.0214548 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0213996 |
| TLK1 | tousled-like kinase 1 | -0.0213498 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0213161 |
| CD109 | CD109 molecule | -0.0211415 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0211388 |
| TMSB4X | thymosin beta 4, X-linked | -0.021066 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0209076 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0206931 |
| THY1 | Thy-1 cell surface antigen | -0.0206746 |
| RPL35A | ribosomal protein L35a | -0.0204897 |
| INHBA | inhibin, beta A | -0.0204837 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0203642 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0203241 |
| IL6 | interleukin 6 | -0.020318 |
| RASAL2 | RAS protein activator like 2 | -0.0202025 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0200826 |
| CTSB | cathepsin B | -0.0199549 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0199494 |
