| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Everolimus perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Everolimus_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.111575 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.110502 |
| PKM | pyruvate kinase, muscle | 0.10539 |
| VIM | vimentin | 0.0881946 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0859094 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0855998 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0815716 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.076021 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.066776 |
| SQSTM1 | sequestosome 1 | 0.0646037 |
| GPC5 | glypican 5 | 0.0640069 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0607821 |
| RPS12 | ribosomal protein S12 | 0.0603136 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0551694 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0530385 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0518407 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0507194 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0498233 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0471544 |
| EFNA5 | ephrin-A5 | 0.0469923 |
| HLA-A | major histocompatibility complex, class I, A | 0.0467039 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0464278 |
| RPS3 | ribosomal protein S3 | 0.0464207 |
| SEPTIN2 | septin 2 | 0.0448088 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0443032 |
| ANXA2 | annexin A2 | 0.0434282 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0430397 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0423776 |
| ENO1 | enolase 1, (alpha) | 0.0421595 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.041296 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0411288 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0410424 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0405306 |
| SVIL | supervillin | 0.0403555 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0398356 |
| GPHN | gephyrin | 0.0396556 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0391326 |
| MAP1B | microtubule-associated protein 1B | 0.0382317 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0380182 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0379705 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0377328 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0376739 |
| RPL37A | ribosomal protein L37a | 0.0371944 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0370202 |
| INTS6 | integrator complex subunit 6 | 0.0366113 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0365683 |
| BPTF | bromodomain PHD finger transcription factor | 0.0360833 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0360083 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.0356142 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0355809 |
| YAP1 | Yes-associated protein 1 | 0.0354322 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0354291 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0348422 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0346049 |
| SET | SET nuclear proto-oncogene | 0.0346019 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0342595 |
| RAB10 | RAB10, member RAS oncogene family | 0.0338826 |
| RTN4 | reticulon 4 | 0.0338505 |
| LDHA | lactate dehydrogenase A | 0.0337282 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.033593 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.0335544 |
| PTK2 | protein tyrosine kinase 2 | 0.0332939 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0332875 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0330252 |
| EEA1 | early endosome antigen 1 | 0.0326357 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.032625 |
| ITSN2 | intersectin 2 | 0.0324776 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0324433 |
| CEP350 | centrosomal protein 350kDa | 0.0322215 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.032005 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0315492 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0310611 |
| RPL9 | ribosomal protein L9 | 0.0309795 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0309069 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0305372 |
| GOLGA4 | golgin A4 | 0.0304834 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0302908 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0301785 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0300025 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0299248 |
| DENND4A | DENN/MADD domain containing 4A | 0.0297855 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0296323 |
| FMNL2 | formin-like 2 | 0.0296109 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0295915 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0295041 |
| ATXN2L | ataxin 2-like | 0.0294155 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0294141 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0294102 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0292458 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0291995 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0291749 |
| DTNA | dystrobrevin, alpha | 0.0286933 |
| B2M | beta-2-microglobulin | 0.0281772 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 0.0281355 |
| MTREX | Mtr4 exosome RNA helicase | 0.0280796 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.028041 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0278588 |
| RNF145 | ring finger protein 145 | 0.0278551 |
| BRD2 | bromodomain containing 2 | 0.027707 |
| RCOR1 | REST corepressor 1 | 0.0275317 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.232877 |
| AHNAK | AHNAK nucleoprotein | -0.118286 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.099026 |
| HMGA2 | high mobility group AT-hook 2 | -0.0890991 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0837578 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0743015 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0730256 |
| ATG7 | autophagy related 7 | -0.0654228 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0639969 |
| FMN1 | formin 1 | -0.0634705 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0629105 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0623842 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0583373 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0574065 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0560837 |
| DNER | delta/notch-like EGF repeat containing | -0.0560784 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0558785 |
| PCNX4 | pecanex 4 | -0.0550726 |
| CANX | calnexin | -0.0501804 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0500155 |
| RAI14 | retinoic acid induced 14 | -0.0488972 |
| RPL35A | ribosomal protein L35a | -0.0484647 |
| ATM | ATM serine/threonine kinase | -0.0483978 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0477836 |
| FLNB | filamin B, beta | -0.0473177 |
| SLC38A2 | solute carrier family 38, member 2 | -0.04685 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0460971 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0459061 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0447963 |
| DENND1A | DENN/MADD domain containing 1A | -0.0446681 |
| SMC4 | structural maintenance of chromosomes 4 | -0.043641 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0435037 |
| TMSB10 | thymosin beta 10 | -0.0432143 |
| PHF3 | PHD finger protein 3 | -0.0418241 |
| RIN2 | Ras and Rab interactor 2 | -0.0403448 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0398393 |
| PODXL | podocalyxin-like | -0.0394015 |
| SDC4 | syndecan 4 | -0.039008 |
| VCL | vinculin | -0.03856 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0384793 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0380275 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0380005 |
| PCED1B | PC-esterase domain containing 1B | -0.0369355 |
| MT2A | metallothionein 2A | -0.0368424 |
| PYGL | phosphorylase, glycogen, liver | -0.0358214 |
| IGF2 | insulin-like growth factor 2 | -0.0356833 |
| RAD51B | RAD51 paralog B | -0.0354752 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.035321 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0350464 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0334652 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0330848 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0328922 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0326702 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0326421 |
| RBM39 | RNA binding motif protein 39 | -0.0325389 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0324577 |
| ZNF644 | zinc finger protein 644 | -0.0323606 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0322527 |
| TMEM123 | transmembrane protein 123 | -0.0321895 |
| EXOC4 | exocyst complex component 4 | -0.0315847 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0314166 |
| AEBP2 | AE binding protein 2 | -0.0307585 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0306319 |
| GOLGA3 | golgin A3 | -0.0305241 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0304387 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0304101 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0303369 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0303277 |
| NDRG1 | N-myc downstream regulated 1 | -0.0301457 |
| ATG10 | autophagy related 10 | -0.0290221 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0289848 |
| SNX9 | sorting nexin 9 | -0.0287174 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0283215 |
| RPL4 | ribosomal protein L4 | -0.028284 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0278597 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0278071 |
| ACTG1 | actin gamma 1 | -0.0275659 |
| ZNF638 | zinc finger protein 638 | -0.027171 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0270359 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0269166 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0268415 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0268378 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0267683 |
| ZNF438 | zinc finger protein 438 | -0.0267618 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0267255 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0263761 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | -0.0263649 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0261736 |
| ASPH | aspartate beta-hydroxylase | -0.0261389 |
| ANLN | anillin, actin binding protein | -0.0259189 |
| NRG1 | neuregulin 1 | -0.0255313 |
| RANBP17 | RAN binding protein 17 | -0.0253578 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0252361 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0252144 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0251241 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0250846 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0249448 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0247634 |
| RPS21 | ribosomal protein S21 | -0.0247088 |
| PGK1 | phosphoglycerate kinase 1 | -0.0245769 |
