| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Everolimus perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Everolimus_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.133948 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0890224 |
| STC2 | stanniocalcin 2 | 0.081281 |
| ASPH | aspartate beta-hydroxylase | 0.0782111 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0746603 |
| MT2A | metallothionein 2A | 0.0735919 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0688163 |
| HMGA2 | high mobility group AT-hook 2 | 0.0676932 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0675866 |
| RPS12 | ribosomal protein S12 | 0.0668325 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0666408 |
| ENO1 | enolase 1, (alpha) | 0.0653502 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0627852 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0580575 |
| EREG | epiregulin | 0.0576285 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0557557 |
| FTL | ferritin, light polypeptide | 0.0554422 |
| RACK1 | receptor for activated C kinase 1 | 0.0554289 |
| PLIN2 | perilipin 2 | 0.0545016 |
| DUSP6 | dual specificity phosphatase 6 | 0.0525573 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0517466 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.051114 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0482272 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0445176 |
| GPC6 | glypican 6 | 0.0442059 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0425514 |
| VIM | vimentin | 0.0422515 |
| TOP1 | topoisomerase (DNA) I | 0.042143 |
| MAP1B | microtubule-associated protein 1B | 0.0410802 |
| FHL2 | four and a half LIM domains 2 | 0.039079 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0386339 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0386292 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0384513 |
| ANGPTL4 | angiopoietin-like 4 | 0.0382461 |
| ANKRD28 | ankyrin repeat domain 28 | 0.037169 |
| SQSTM1 | sequestosome 1 | 0.0358621 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0353973 |
| GPATCH2L | G patch domain containing 2-like | 0.0345188 |
| INTS6 | integrator complex subunit 6 | 0.0338871 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0337446 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0328974 |
| LMNA | lamin A/C | 0.032355 |
| RAB10 | RAB10, member RAS oncogene family | 0.0322423 |
| DSTN | destrin (actin depolymerizing factor) | 0.0320637 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0318487 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.0317496 |
| RPL37A | ribosomal protein L37a | 0.0310729 |
| SVIL | supervillin | 0.0309025 |
| LYST | lysosomal trafficking regulator | 0.0307761 |
| IL6ST | interleukin 6 signal transducer | 0.0307032 |
| HYOU1 | hypoxia up-regulated 1 | 0.0303934 |
| LOXL2 | lysyl oxidase-like 2 | 0.030278 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0294537 |
| RPS3 | ribosomal protein S3 | 0.0291772 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0289043 |
| FLNA | filamin A, alpha | 0.0288504 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0282426 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0278868 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0278436 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0277649 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0274895 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0274724 |
| FAT1 | FAT atypical cadherin 1 | 0.0274186 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0273586 |
| RPL9 | ribosomal protein L9 | 0.0272704 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0270306 |
| AREG | amphiregulin | 0.0268303 |
| TXNIP | thioredoxin interacting protein | 0.0267887 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0264641 |
| PALLD | palladin, cytoskeletal associated protein | 0.0263298 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0260455 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0258645 |
| PCDH7 | protocadherin 7 | 0.0256619 |
| IGF2 | insulin-like growth factor 2 | 0.0253693 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0251163 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0251131 |
| SEPTIN9 | septin 9 | 0.0248512 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0248202 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0241007 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.024053 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0236761 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0236598 |
| RPL26 | ribosomal protein L26 | 0.0232405 |
| FERMT2 | fermitin family member 2 | 0.0231434 |
| FHIT | fragile histidine triad | 0.0230772 |
| VCL | vinculin | 0.0230037 |
| HLA-A | major histocompatibility complex, class I, A | 0.0229277 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0226692 |
| MTDH | metadherin | 0.0226635 |
| RPS2 | ribosomal protein S2 | 0.022399 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0223982 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0223894 |
| MYO9A | myosin IXA | 0.0222304 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0222146 |
| CTBP2 | C-terminal binding protein 2 | 0.0218352 |
| RPS7 | ribosomal protein S7 | 0.021623 |
| LDHA | lactate dehydrogenase A | 0.0214948 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0213216 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.021291 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0211371 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.278181 |
| NRG1 | neuregulin 1 | -0.167662 |
| FN1 | fibronectin 1 | -0.166859 |
| PTMA | prothymosin, alpha | -0.133956 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.12058 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.100588 |
| TMSB10 | thymosin beta 10 | -0.0997682 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0894961 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0883134 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0764468 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0758172 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0735374 |
| HLA-B | major histocompatibility complex, class I, B | -0.0710236 |
| CANX | calnexin | -0.0695225 |
| RPL35A | ribosomal protein L35a | -0.068776 |
| NDRG1 | N-myc downstream regulated 1 | -0.0640876 |
| TMSB4X | thymosin beta 4, X-linked | -0.0597167 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0534532 |
| RBM39 | RNA binding motif protein 39 | -0.0522601 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0511872 |
| H1-0 | H1.0 linker histone | -0.0506311 |
| ACTG1 | actin gamma 1 | -0.0500959 |
| TMEM156 | transmembrane protein 156 | -0.0486596 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0450695 |
| RPS6 | ribosomal protein S6 | -0.0449814 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0421225 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.041919 |
| ZNF292 | zinc finger protein 292 | -0.0415145 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0408132 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0407893 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0399459 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0397023 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0395421 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0387212 |
| UBC | ubiquitin C | -0.0385351 |
| ITGA1 | integrin, alpha 1 | -0.0384943 |
| RHEB | Ras homolog enriched in brain | -0.0384427 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0381662 |
| SPAG9 | sperm associated antigen 9 | -0.0364069 |
| POTEF | POTE ankyrin domain family, member F | -0.0359152 |
| AHNAK | AHNAK nucleoprotein | -0.0346469 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.034616 |
| RNF145 | ring finger protein 145 | -0.0346075 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0334574 |
| PARD3 | par-3 family cell polarity regulator | -0.0333771 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0330464 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.032917 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0326045 |
| RPL34 | ribosomal protein L34 | -0.0324284 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0320681 |
| TFG | TRK-fused gene | -0.0318538 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0317847 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0317174 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0314983 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0313606 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0309958 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0309118 |
| KRT81 | keratin 81, type II | -0.030559 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0302394 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0299105 |
| RPS21 | ribosomal protein S21 | -0.0298516 |
| IER3 | immediate early response 3 | -0.0297553 |
| RPL11 | ribosomal protein L11 | -0.0295316 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0291222 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0291097 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0287575 |
| RAB7A | RAB7A, member RAS oncogene family | -0.028726 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0286939 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0284889 |
| RPS11 | ribosomal protein S11 | -0.0281461 |
| TPD52 | tumor protein D52 | -0.0280972 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0280446 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0279316 |
| RBM25 | RNA binding motif protein 25 | -0.0279283 |
| ARF1 | ADP-ribosylation factor 1 | -0.0275291 |
| PTK2 | protein tyrosine kinase 2 | -0.0273381 |
| KLHL24 | kelch-like family member 24 | -0.0271465 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0271238 |
| OGA | O-GlcNAcase | -0.0268735 |
| KLHL5 | kelch-like family member 5 | -0.0268664 |
| FBXO11 | F-box protein 11 | -0.0268131 |
| FAM168B | family with sequence similarity 168, member B | -0.0267998 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0266664 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0266368 |
| HELZ | helicase with zinc finger | -0.0266179 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0265973 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0265313 |
| SDC4 | syndecan 4 | -0.0263599 |
| QKI | QKI, KH domain containing, RNA binding | -0.0261336 |
| NOP58 | NOP58 ribonucleoprotein | -0.0260649 |
| PCBP2 | poly(rC) binding protein 2 | -0.0256392 |
| BBX | bobby sox homolog (Drosophila) | -0.0252661 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.025191 |
| HBP1 | HMG-box transcription factor 1 | -0.0251864 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0250714 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | -0.0248118 |
| ATN1 | atrophin 1 | -0.0247543 |
| USP3 | ubiquitin specific peptidase 3 | -0.024694 |
| COPA | coatomer protein complex, subunit alpha | -0.0245276 |
| FUS | FUS RNA binding protein | -0.0244999 |
