Ewings Sarcoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0553580
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Genes

469 genes associated with the disease Ewings Sarcoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABHD6 abhydrolase domain containing 6
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
ACKR3 atypical chemokine receptor 3
ACSS2 acyl-CoA synthetase short-chain family member 2
ACTB actin, beta
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADRB3 adrenoceptor beta 3
AGO2 argonaute RISC catalytic component 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
ALCAM activated leukocyte cell adhesion molecule
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
APOC3 apolipoprotein C-III
ARHGAP1 Rho GTPase activating protein 1
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARID1A AT rich interactive domain 1A (SWI-like)
ARR3 arrestin 3, retinal (X-arrestin)
ASXL1 additional sex combs like transcriptional regulator 1
ATF1 activating transcription factor 1
ATG4B autophagy related 4B, cysteine peptidase
ATR ATR serine/threonine kinase
AURKB aurora kinase B
AXL AXL receptor tyrosine kinase
BANF1 barrier to autointegration factor 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCAR1 breast cancer anti-estrogen resistance 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2 B-cell CLL/lymphoma 2
BCOR BCL6 corepressor
BCR breakpoint cluster region
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
BID BH3 interacting domain death agonist
BMI1 BMI1 proto-oncogene, polycomb ring finger
BORCS5 BLOC-1 related complex subunit 5
BRCA1 breast cancer 1, early onset
BRD2 bromodomain containing 2
BRD4 bromodomain containing 4
BTK Bruton agammaglobulinemia tyrosine kinase
C1ORF127 chromosome 1 open reading frame 127
C1ORF228 chromosome 1 open reading frame 228
CACUL1 CDK2-associated, cullin domain 1
CALCA calcitonin-related polypeptide alpha
CALCB calcitonin-related polypeptide beta
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CAVIN1 caveolae associated protein 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCK cholecystokinin
CCL21 chemokine (C-C motif) ligand 21
CCNB3 cyclin B3
CCND1 cyclin D1
CCND2 cyclin D2
CCNL1 cyclin L1
CD248 CD248 molecule, endosialin
CD274 CD274 molecule
CD276 CD276 molecule
CD34 CD34 molecule
CD38 CD38 molecule
CD6 CD6 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CD82 CD82 molecule
CD86 CD86 molecule
CD99 CD99 molecule
CDC42 cell division cycle 42
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK12 cyclin-dependent kinase 12
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDK6 cyclin-dependent kinase 6
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEP41 centrosomal protein 41kDa
CHEK1 checkpoint kinase 1
CHP1 calcineurin-like EF-hand protein 1
CHPT1 choline phosphotransferase 1
CIC capicua transcriptional repressor
CIZ1 CDKN1A interacting zinc finger protein 1
COL11A2 collagen, type XI, alpha 2
COMMD3-BMI1 COMMD3-BMI1 readthrough
CRP C-reactive protein, pentraxin-related
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSF1R colony stimulating factor 1 receptor
CSF3 colony stimulating factor 3 (granulocyte)
CTAG1A cancer/testis antigen 1A
CTAG1B cancer/testis antigen 1B
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CXADR coxsackie virus and adenovirus receptor
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
DCC DCC netrin 1 receptor
DCLK3 doublecortin-like kinase 3
DDIT3 DNA-damage-inducible transcript 3
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DHDDS dehydrodolichyl diphosphate synthase
DKK2 dickkopf WNT signaling pathway inhibitor 2
DNER delta/notch-like EGF repeat containing
DPP4 dipeptidyl-peptidase 4
DSPP dentin sialophosphoprotein
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DUX4 double homeobox 4
E2F3 E2F transcription factor 3
E2F4 E2F transcription factor 4, p107/p130-binding
EBNA1BP2 EBNA1 binding protein 2
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
EED embryonic ectoderm development
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EGR2 early growth response 2
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EMD emerin
EMG1 EMG1 N1-specific pseudouridine methyltransferase
ENG endoglin
EPHA2 EPH receptor A2
EPHA3 EPH receptor A3
EPHB2 EPH receptor B2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB4 erb-b2 receptor tyrosine kinase 4
ERF Ets2 repressor factor
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ERN1 endoplasmic reticulum to nucleus signaling 1
ERVFRD-1 endogenous retrovirus group FRD, member 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV1 ets variant 1
ETV4 ets variant 4
ETV5 ets variant 5
EWSR1 EWS RNA-binding protein 1
EYA3 EYA transcriptional coactivator and phosphatase 3
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
EZR ezrin
FAP fibroblast activation protein, alpha
FAS Fas cell surface death receptor
FATE1 fetal and adult testis expressed 1
FBXW11 F-box and WD repeat domain containing 11
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FEV FEV (ETS oncogene family)
FGF2 fibroblast growth factor 2 (basic)
FGF4 fibroblast growth factor 4
FGFR1 fibroblast growth factor receptor 1
FHIT fragile histidine triad
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLII flightless I homolog (Drosophila)
FLT3 fms-related tyrosine kinase 3
FLT4 fms-related tyrosine kinase 4
FN1 fibronectin 1
FNDC5 fibronectin type III domain containing 5
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXC1 forkhead box C1
FOXM1 forkhead box M1
FOXO1 forkhead box O1
FOXP4 forkhead box P4
FOXQ1 forkhead box Q1
FUS FUS RNA binding protein
GAB1 GRB2-associated binding protein 1
GAS6 growth arrest-specific 6
GATA3 GATA binding protein 3
GDE1 glycerophosphodiester phosphodiesterase 1
GDNF glial cell derived neurotrophic factor
GHRH growth hormone releasing hormone
GJA1 gap junction protein, alpha 1, 43kDa
GLG1 golgi glycoprotein 1
GLI1 GLI family zinc finger 1
GRB10 growth factor receptor-bound protein 10
GSTK1 glutathione S-transferase kappa 1
GSTM4 glutathione S-transferase mu 4
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
H2AX H2A.X variant histone
HDAC3 histone deacetylase 3
HDGF hepatoma-derived growth factor
HEATR3 HEAT repeat containing 3
HES1 hes family bHLH transcription factor 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-G major histocompatibility complex, class I, G
HMGA2 high mobility group AT-hook 2
HOXD11 homeobox D11
HOXD13 homeobox D13
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA4 heat shock 70kDa protein 4
HSPB1 heat shock 27kDa protein 1
HSPB2 heat shock 27kDa protein 2
HSPB3 heat shock 27kDa protein 3
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP3 insulin-like growth factor binding protein 3
IGL immunoglobulin lambda locus
IHH indian hedgehog
IL15 interleukin 15
IL2 interleukin 2
IL31RA interleukin 31 receptor A
IL6 interleukin 6
IL9 interleukin 9
ILK integrin-linked kinase
INSM1 insulinoma-associated 1
INSR insulin receptor
INSRR insulin receptor-related receptor
JAK1 Janus kinase 1
JTB jumping translocation breakpoint
JUN jun proto-oncogene
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KDM1A lysine (K)-specific demethylase 1A
KDM1B lysine (K)-specific demethylase 1B
KDM3A lysine (K)-specific demethylase 3A
KIDINS220 kinase D-interacting substrate, 220kDa
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLK3 kallikrein-related peptidase 3
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT17 keratin 17, type I
KRT20 keratin 20, type I
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LDHA lactate dehydrogenase A
LECT1 leukocyte cell derived chemotaxin 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LIF leukemia inhibitory factor
LIN28A lin-28 homolog A (C. elegans)
LINGO1 leucine rich repeat and Ig domain containing 1
LMO3 LIM domain only 3 (rhombotin-like 2)
LOX lysyl oxidase
LPP LIM domain containing preferred translocation partner in lipoma
LRP1 low density lipoprotein receptor-related protein 1
LRWD1 leucine-rich repeats and WD repeat domain containing 1
MAML3 mastermind-like 3 (Drosophila)
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
MBD2 methyl-CpG binding domain protein 2
MCAM melanoma cell adhesion molecule
MCF2 MCF.2 cell line derived transforming sequence
MCL1 myeloid cell leukemia 1
MDK midkine (neurite growth-promoting factor 2)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEIS1 Meis homeobox 1
MEN1 multiple endocrine neoplasia I
MET MET proto-oncogene, receptor tyrosine kinase
MGST1 microsomal glutathione S-transferase 1
MLH1 mutL homolog 1
MLXIP MLX interacting protein
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MMP11 matrix metallopeptidase 11
MMP9 matrix metallopeptidase 9
MMRN1 multimerin 1
MRPL41 mitochondrial ribosomal protein L41
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYLIP myosin regulatory light chain interacting protein
NAMPT nicotinamide phosphoribosyltransferase
NCAM1 neural cell adhesion molecule 1
NECTIN2 nectin cell adhesion molecule 2
NES nestin
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NGF nerve growth factor (beta polypeptide)
NKAP NFKB activating protein
NKX2-2 NK2 homeobox 2
NME1 NME/NM23 nucleoside diphosphate kinase 1
NME1-NME2 NME1-NME2 readthrough
NME2 NME/NM23 nucleoside diphosphate kinase 2
NNAT neuronatin
NOTCH1 notch 1
NOV nephroblastoma overexpressed
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPTX2 neuronal pentraxin II
NPY neuropeptide Y
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR1I3 nuclear receptor subfamily 1, group I, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRG1 neuregulin 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUTM1 NUT midline carcinoma, family member 1
OLFM1 olfactomedin 1
OSM oncostatin M
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARP1 poly (ADP-ribose) polymerase 1
PAX3 paired box 3
PAX7 paired box 7
PBK PDZ binding kinase
PCNA proliferating cell nuclear antigen
PDCD1 programmed cell death 1
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PGP phosphoglycolate phosphatase
PHF11 PHD finger protein 11
PHF19 PHD finger protein 19
PHGDH phosphoglycerate dehydrogenase
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLA2G15 phospholipase A2, group XV
PLK1 polo-like kinase 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POU5F1 POU class 5 homeobox 1
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRF1 perforin 1 (pore forming protein)
PRIMA1 proline rich membrane anchor 1
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRMT8 protein arginine methyltransferase 8
PROM1 prominin 1
PRRT2 proline-rich transmembrane protein 2
PSAT1 phosphoserine aminotransferase 1
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSPH phosphoserine phosphatase
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRD protein tyrosine phosphatase, receptor type, D
RABEPK Rab9 effector protein with kelch motifs
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAG2 recombination activating gene 2
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RB1 retinoblastoma 1
REEP5 receptor accessory protein 5
RELN reelin
REST RE1-silencing transcription factor
RET ret proto-oncogene
RHD Rh blood group, D antigen
RHOV ras homolog family member V
RITA1 RBPJ interacting and tubulin associated 1
RNF2 ring finger protein 2
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
ROR1 receptor tyrosine kinase-like orphan receptor 1
RPSA ribosomal protein SA
RUNX2 runt-related transcription factor 2
RUNX3 runt-related transcription factor 3
S100A1 S100 calcium binding protein A1
S100A12 S100 calcium binding protein A12
S100B S100 calcium binding protein B
SATB2 SATB homeobox 2
SCG2 secretogranin II
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SET SET nuclear proto-oncogene
SETD2 SET domain containing 2
SF3B1 splicing factor 3b, subunit 1, 155kDa
SFRP5 secreted frizzled-related protein 5
SH2D1B SH2 domain containing 1B
SH2D4B SH2 domain containing 4B
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SLFN11 schlafen family member 11
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMN1 survival of motor neuron 1, telomeric
SMN2 survival of motor neuron 2, centromeric
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNRPN small nuclear ribonucleoprotein polypeptide N
SNURF SNRPN upstream reading frame
SOX17 SRY (sex determining region Y)-box 17
SOX2 SRY (sex determining region Y)-box 2
SP1 Sp1 transcription factor
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SPN sialophorin
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SST somatostatin
SSX1 synovial sarcoma, X breakpoint 1
STAG1 stromal antigen 1
STAG2 stromal antigen 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STEAP1 six transmembrane epithelial antigen of the prostate 1
STMN1 stathmin 1
STRAP serine/threonine kinase receptor associated protein
SUZ12 SUZ12 polycomb repressive complex 2 subunit
SYK spleen tyrosine kinase
SYP synaptophysin
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TARBP2 TAR (HIV-1) RNA binding protein 2
TARDBP TAR DNA binding protein
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBX5 T-box 5
TCF4 transcription factor 4
TERT telomerase reverse transcriptase
TET2 tet methylcytosine dioxygenase 2
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THY1 Thy-1 cell surface antigen
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMPRSS2 transmembrane protease, serine 2
TNC tenascin C
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNNT1 troponin T type 1 (skeletal, slow)
TP53 tumor protein p53
TP53I3 tumor protein p53 inducible protein 3
TP63 tumor protein p63
TRIB1 tribbles pseudokinase 1
TRIM13 tripartite motif containing 13
TRIP6 thyroid hormone receptor interactor 6
TSPAN7 tetraspanin 7
TWIST1 twist family bHLH transcription factor 1
USP19 ubiquitin specific peptidase 19
USP6 ubiquitin specific peptidase 6
VEGFA vascular endothelial growth factor A
VIM vimentin
WNT5A wingless-type MMTV integration site family, member 5A
WT1 Wilms tumor 1
XAGE1A X antigen family member 1A
XAGE1E X antigen family, member 1E
XBP1 X-box binding protein 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XYLT2 xylosyltransferase II
YAP1 Yes-associated protein 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB16 zinc finger and BTB domain containing 16
ZBTB4 zinc finger and BTB domain containing 4
ZNF331 zinc finger protein 331
ZNF93 zinc finger protein 93
ZYX zyxin