Exercise Test Gene Set

Dataset dbGAP Gene-Trait Associations
Category disease or phenotype associations
Type trait
Description Controlled physical activity, more strenuous than at rest, which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used. The intensity of exercise is often graded, using criteria such as rate of work done, oxygen consumption, and heart rate. (Experimental Factor Ontology, EFO_0004328)
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Genes

68 genes associated with the trait Exercise Test in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

Symbol Name Standardized Value
TMOD3 tropomodulin 3 (ubiquitous) 1.1567
EFNA5 ephrin-A5 1.13308
OPCML opioid binding protein/cell adhesion molecule-like 0.968925
CDK8 cyclin-dependent kinase 8 0.915611
CYYR1 cysteine/tyrosine-rich 1 0.859772
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.85522
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.795249
ELMO1 engulfment and cell motility 1 0.749808
KCNIP4 Kv channel interacting protein 4 0.73239
PDZRN4 PDZ domain containing ring finger 4 0.687076
CDH10 cadherin 10, type 2 (T2-cadherin) 0.628068
MSRB3 methionine sulfoxide reductase B3 0.618477
ARHGAP10 Rho GTPase activating protein 10 0.614296
TMOD2 tropomodulin 2 (neuronal) 0.609873
EBF2 early B-cell factor 2 0.604228
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 0.593643
AFF3 AF4/FMR2 family, member 3 0.579548
PBLD phenazine biosynthesis-like protein domain containing 0.578988
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.571223
LAMA2 laminin, alpha 2 0.562716
EGFLAM EGF-like, fibronectin type III and laminin G domains 0.559302
RYR3 ryanodine receptor 3 0.549398
ARSB arylsulfatase B 0.531153
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 0.507166
FRMPD4 FERM and PDZ domain containing 4 0.483572
THSD7B thrombospondin, type I, domain containing 7B 0.456457
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0.440488
ATG10 autophagy related 10 0.429758
WIF1 WNT inhibitory factor 1 0.418239
FMN2 formin 2 0.415082
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 0.404897
GJA5 gap junction protein, alpha 5, 40kDa 0.393732
RYR2 ryanodine receptor 2 (cardiac) 0.391314
SHROOM4 shroom family member 4 0.376157
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 0.371347
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.369609
ZC3H12C zinc finger CCCH-type containing 12C 0.359216
WRN Werner syndrome, RecQ helicase-like 0.33862
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.3252
ADCY8 adenylate cyclase 8 (brain) 0.321187
CSMD1 CUB and Sushi multiple domains 1 0.308301
NPAS3 neuronal PAS domain protein 3 0.304672
FAM76A family with sequence similarity 76, member A 0.291693
CNTN4 contactin 4 0.2895
TMEM131 transmembrane protein 131 0.282971
RARB retinoic acid receptor, beta 0.25342
PCDH15 protocadherin-related 15 0.24985
SGCZ sarcoglycan, zeta 0.242563
VAV3 vav 3 guanine nucleotide exchange factor 0.227314
DMD dystrophin 0.221281
FLT1 fms-related tyrosine kinase 1 0.196076
MIR99AHG mir-99a-let-7c cluster host gene 0.19421
SPINK14 serine peptidase inhibitor, Kazal type 14 (putative) 0.190968
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 0.185931
SPRN shadow of prion protein homolog (zebrafish) 0.181861
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.162042
SCHIP1 schwannomin interacting protein 1 0.149492
PTPRQ protein tyrosine phosphatase, receptor type, Q 0.149492
EPS8 epidermal growth factor receptor pathway substrate 8 0.129111
TMEM244 transmembrane protein 244 0.116929
FAF1 Fas (TNFRSF6) associated factor 1 0.112888
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 0.109388
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 0.100542
SPAG16 sperm associated antigen 16 0.099572
ABHD5 abhydrolase domain containing 5 0.094285
TSPAN5 tetraspanin 5 0.087241
CDH18 cadherin 18, type 2 0.080798
CNGB3 cyclic nucleotide gated channel beta 3 0.063335