Exocrine Pancreatic Insufficiency Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0267963
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Genes

80 genes associated with the disease Exocrine Pancreatic Insufficiency in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ADRB2 adrenoceptor beta 2, surface
ALB albumin
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARX aristaless related homeobox
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
BLK BLK proto-oncogene, Src family tyrosine kinase
BPTF bromodomain PHD finger transcription factor
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CCL21 chemokine (C-C motif) ligand 21
CDKN2A cyclin-dependent kinase inhibitor 2A
CEL carboxyl ester lipase
CELA1 chymotrypsin-like elastase family, member 1
CELA3A chymotrypsin-like elastase family, member 3A
CELA3B chymotrypsin-like elastase family, member 3B
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHEK1 checkpoint kinase 1
CLCA4 chloride channel accessory 4
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung)
CTNS cystinosin, lysosomal cystine transporter
CTRC chymotrypsin C (caldecrin)
CTRL chymotrypsin-like
DCTN4 dynactin 4 (p62)
DNAJC21 DnaJ (Hsp40) homolog, subfamily C, member 21
EFL1 elongation factor like GTPase 1
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
GATA6 GATA binding protein 6
GCK glucokinase (hexokinase 4)
GIP gastric inhibitory polypeptide
GLIS3 GLIS family zinc finger 3
GSTP1 glutathione S-transferase pi 1
HFE hemochromatosis
HNF1A HNF1 homeobox A
HNF1B HNF1 homeobox B
HNF4A hepatocyte nuclear factor 4, alpha
HPGDS hematopoietic prostaglandin D synthase
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
INS insulin
JAG1 jagged 1
KCNIP4 Kv channel interacting protein 4
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KEAP1 kelch-like ECH-associated protein 1
KLF11 Kruppel-like factor 11
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT8 keratin 8, type II
MLN motilin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC16 mucin 16, cell surface associated
MUS81 MUS81 structure-specific endonuclease subunit
NEUROD1 neuronal differentiation 1
OFD1 oral-facial-digital syndrome 1
OGG1 8-oxoguanine DNA glycosylase
PALB2 partner and localizer of BRCA2
PALLD palladin, cytoskeletal associated protein
PAX4 paired box 4
PDX1 pancreatic and duodenal homeobox 1
PRSS1 protease, serine, 1 (trypsin 1)
PRSS2 protease, serine, 2 (trypsin 2)
PUF60 poly-U binding splicing factor 60KDa
REG1A regenerating islet-derived 1 alpha
SBDS Shwachman-Bodian-Diamond syndrome
SCT secretin
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
SMAD4 SMAD family member 4
SPINK1 serine peptidase inhibitor, Kazal type 1
SRP54 signal recognition particle 54kDa
SST somatostatin
STX1A syntaxin 1A (brain)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor
TP53 tumor protein p53
TTR transthyretin
TXNRD1 thioredoxin reductase 1
UBR1 ubiquitin protein ligase E3 component n-recognin 1
VWF von Willebrand factor
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1