Exotropia Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

235 genes co-occuring with the disease Exotropia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
PHOX2A paired-like homeobox 2a 2.882
KIF21A kinesin family member 21A 2.843
TUBB3 tubulin, beta 3 class III 2.226
ZC4H2 zinc finger, C4H2 domain containing 2.091
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 2.006
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 1.936
PHOX2B paired-like homeobox 2b 1.92
COL25A1 collagen, type XXV, alpha 1 1.895
FAM50A family with sequence similarity 50, member A 1.882
FRMD7 FERM domain containing 7 1.839
TSPAN10 tetraspanin 10 1.824
PAX6 paired box 6 1.805
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1 1.759
XYLT1 xylosyltransferase I 1.754
CHN1 chimerin 1 1.734
GPR143 G protein-coupled receptor 143 1.7
ECEL1 endothelin converting enzyme-like 1 1.686
SATL1 spermidine/spermine N1-acetyl transferase-like 1 1.684
PTRH2 peptidyl-tRNA hydrolase 2 1.68
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 1.676
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 1.652
FGFR2 fibroblast growth factor receptor 2 1.592
OTX2 orthodenticle homeobox 2 1.564
TUBB2B tubulin, beta 2B class IIb 1.56
SALL4 spalt-like transcription factor 4 1.542
HPS3 Hermansky-Pudlak syndrome 3 1.536
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma 1.536
HPS6 Hermansky-Pudlak syndrome 6 1.517
PITX2 paired-like homeodomain 2 1.511
RPE65 retinal pigment epithelium-specific protein 65kDa 1.5
SMAD9 SMAD family member 9 1.494
TMEM11 transmembrane protein 11 1.484
CHD7 chromodomain helicase DNA binding protein 7 1.474
FA2H fatty acid 2-hydroxylase 1.468
ASXL3 additional sex combs like transcriptional regulator 3 1.453
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 1.447
FAM241A family with sequence similarity 241 member A 1.445
ZGRF1 zinc finger, GRF-type containing 1 1.439
HPS5 Hermansky-Pudlak syndrome 5 1.436
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3 1.431
PRDM5 PR domain containing 5 1.424
CENPVL1 centromere protein V like 1 1.424
RS1 retinoschisin 1 1.422
FBN1 fibrillin 1 1.418
MGST2 microsomal glutathione S-transferase 2 1.405
CEP290 centrosomal protein 290kDa 1.399
NYX nyctalopin 1.399
MYH13 myosin, heavy chain 13, skeletal muscle 1.398
MECP2 methyl CpG binding protein 2 1.395
GPR179 G protein-coupled receptor 179 1.386
ZNF408 zinc finger protein 408 1.385
ALMS1 Alstrom syndrome protein 1 1.379
OCA2 oculocutaneous albinism II 1.376
FMR1 fragile X mental retardation 1 1.363
TSPAN12 tetraspanin 12 1.357
NECAP1 NECAP endocytosis associated 1 1.353
FOXC1 forkhead box C1 1.352
PPIAP39 peptidylprolyl isomerase A pseudogene 39 1.342
BBS1 Bardet-Biedl syndrome 1 1.339
TTLL5 tubulin tyrosine ligase-like family member 5 1.334
NF1 neurofibromin 1 1.33
TCTN2 tectonic family member 2 1.33
TRIM8 tripartite motif containing 8 1.329
TTLL10 tubulin tyrosine ligase-like family member 10 1.326
MBD3L4 methyl-CpG binding domain protein 3-like 4 1.325
TMEM64 transmembrane protein 64 1.322
PRAMEF25 PRAME family member 25 1.321
SPATA7 spermatogenesis associated 7 1.32
MUSK muscle, skeletal, receptor tyrosine kinase 1.319
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 1.318
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 1.308
FGFR3 fibroblast growth factor receptor 3 1.308
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 1.3
LGI2 leucine-rich repeat LGI family, member 2 1.298
HESX1 HESX homeobox 1 1.296
PRR12 proline rich 12 1.294
VPREB1 pre-B lymphocyte 1 1.291
IQCB1 IQ motif containing B1 1.29
FAM170A family with sequence similarity 170, member A 1.285
BTD biotinidase 1.284
MYH14 myosin, heavy chain 14, non-muscle 1.281
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis) 1.28
AP1AR adaptor-related protein complex 1 associated regulatory protein 1.279
CC2D2A coiled-coil and C2 domain containing 2A 1.276
IGF1 insulin-like growth factor 1 (somatomedin C) 1.271
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10 1.271
TRABD2A TraB domain containing 2A 1.266
NPHP1 nephronophthisis 1 (juvenile) 1.262
WDPCP WD repeat containing planar cell polarity effector 1.262
LRIT3 leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 1.261
TUBA1A tubulin, alpha 1a 1.253
CNGB3 cyclic nucleotide gated channel beta 3 1.252
TRPM1 transient receptor potential cation channel, subfamily M, member 1 1.25
MOG myelin oligodendrocyte glycoprotein 1.249
PRAMEF14 PRAME family member 14 1.249
TMEM126A transmembrane protein 126A 1.245
POMGNT2 protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) 1.238
SDCCAG8 serologically defined colon cancer antigen 8 1.234
ADAMTSL2 ADAMTS-like 2 1.231
ALG12 ALG12, alpha-1,6-mannosyltransferase 1.23
HPS4 Hermansky-Pudlak syndrome 4 1.222
RERE arginine-glutamic acid dipeptide (RE) repeats 1.221
AHI1 Abelson helper integration site 1 1.22
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 1.22
PRDM13 PR domain containing 13 1.215
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 1.214
HOXB1 homeobox B1 1.21
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.209
CKMT1B creatine kinase, mitochondrial 1B 1.208
RPGR retinitis pigmentosa GTPase regulator 1.208
MAN2C1 mannosidase, alpha, class 2C, member 1 1.207
CKB creatine kinase, brain 1.205
SIX3 SIX homeobox 3 1.205
CKM creatine kinase, muscle 1.203
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 1.202
OR4L1 olfactory receptor, family 4, subfamily L, member 1 1.202
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 1.193
SNRPN small nuclear ribonucleoprotein polypeptide N 1.189
TULP1 tubby like protein 1 1.188
UBE3A ubiquitin protein ligase E3A 1.187
NR2F2 nuclear receptor subfamily 2, group F, member 2 1.182
CRX cone-rod homeobox 1.181
MAGEL2 melanoma antigen family L2 1.176
NIPBL Nipped-B homolog (Drosophila) 1.173
GOLGA8R golgin A8 family, member R 1.172
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 1.171
SHPK sedoheptulokinase 1.169
SLITRK2 SLIT and NTRK-like family, member 2 1.168
LOXHD1 lipoxygenase homology domains 1 1.167
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 1.162
NGLY1 N-glycanase 1 1.148
C19ORF25 chromosome 19 open reading frame 25 1.144
APOOL apolipoprotein O-like 1.142
CDKL5 cyclin-dependent kinase-like 5 1.141
MRPL41 mitochondrial ribosomal protein L41 1.139
FAM25C family with sequence similarity 25, member C 1.137
POF1B premature ovarian failure, 1B 1.131
RPGRIP1L RPGRIP1-like 1.131
COL19A1 collagen, type XIX, alpha 1 1.13
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 1.13
LCA5L Leber congenital amaurosis 5-like 1.128
PTCD3 pentatricopeptide repeat domain 3 1.126
WFS1 Wolfram syndrome 1 (wolframin) 1.125
PRELID1 PRELI domain containing 1 1.123
TMEM67 transmembrane protein 67 1.12
EVC2 Ellis van Creveld syndrome 2 1.119
SACS sacsin molecular chaperone 1.119
DTNBP1 dystrobrevin binding protein 1 1.116
ZNF711 zinc finger protein 711 1.115
MYH1 myosin, heavy chain 1, skeletal muscle, adult 1.115
GJA3 gap junction protein, alpha 3, 46kDa 1.113
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 1.113
CRYBB1 crystallin, beta B1 1.108
NF2 neurofibromin 2 (merlin) 1.106
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 1.103
AHDC1 AT hook, DNA binding motif, containing 1 1.103
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 1.1
GLRA2 glycine receptor, alpha 2 1.099
AUH AU RNA binding protein/enoyl-CoA hydratase 1.098
NCOA7 nuclear receptor coactivator 7 1.095
PHF21A PHD finger protein 21A 1.093
COL2A1 collagen, type II, alpha 1 1.09
ESX1 ESX homeobox 1 1.09
GDI1 GDP dissociation inhibitor 1 1.09
PCDH12 protocadherin 12 1.089
NDE1 nudE neurodevelopment protein 1 1.088
CIB3 calcium and integrin binding family member 3 1.086
RETSAT retinol saturase (all-trans-retinol 13,14-reductase) 1.084
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 1.083
MBD3L3 methyl-CpG binding domain protein 3-like 3 1.08
RP1L1 retinitis pigmentosa 1-like 1 1.079
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe) 1.079
WDR62 WD repeat domain 62 1.079
TYR tyrosinase 1.076
ZNF665 zinc finger protein 665 1.074
SHH sonic hedgehog 1.074
PCDHA1 protocadherin alpha 1 1.074
PAX2 paired box 2 1.074
LIMS3 LIM and senescent cell antigen-like domains 3 1.073
AMTN amelotin 1.07
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 1.069
ADNP activity-dependent neuroprotector homeobox 1.068
COQ8A coenzyme Q8A 1.067
BBS10 Bardet-Biedl syndrome 10 1.066
KCTD1 potassium channel tetramerization domain containing 1 1.066
PEX6 peroxisomal biogenesis factor 6 1.065
ZNF469 zinc finger protein 469 1.062
ANTXRL anthrax toxin receptor-like 1.062
ARV1 ARV1 homolog (S. cerevisiae) 1.061
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 1.058
KAT6B K(lysine) acetyltransferase 6B 1.057
PLPPR4 phospholipid phosphatase related 4 1.055
MECR mitochondrial trans-2-enoyl-CoA reductase 1.055
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 1.055
POMC proopiomelanocortin 1.054
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 1.053
MKRN3 makorin ring finger protein 3 1.053
CEP85L centrosomal protein 85kDa-like 1.052
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 1.052
SUB1 SUB1 homolog (S. cerevisiae) 1.052
GFAP glial fibrillary acidic protein 1.051
C11ORF91 chromosome 11 open reading frame 91 1.05
DMPK dystrophia myotonica-protein kinase 1.049
EDN2 endothelin 2 1.044
CABP4 calcium binding protein 4 1.041
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 1.04
CNGA3 cyclic nucleotide gated channel alpha 3 1.039
EFNB1 ephrin-B1 1.037
KERA keratocan 1.037
PRSS56 protease, serine, 56 1.037
COL9A1 collagen, type IX, alpha 1 1.036
DACH2 dachshund family transcription factor 2 1.035
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 1.03
GJA8 gap junction protein, alpha 8, 50kDa 1.029
PANK2 pantothenate kinase 2 1.028
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 1.028
TENM3 teneurin transmembrane protein 3 1.027
WNT2 wingless-type MMTV integration site family member 2 1.022
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 1.021
ICE1 interactor of little elongation complex ELL subunit 1 1.019
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) 1.019
PCDH11X protocadherin 11 X-linked 1.018
COL11A2 collagen, type XI, alpha 2 1.017
OR4F17 olfactory receptor, family 4, subfamily F, member 17 1.016
MFSD8 major facilitator superfamily domain containing 8 1.016
FZD4 frizzled class receptor 4 1.014
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 1.014
ZIC2 Zic family member 2 1.013
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 1.013
GET1 guided entry of tail-anchored proteins factor 1 1.012
FOXE3 forkhead box E3 1.012
AUTS2 autism susceptibility candidate 2 1.011
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.01
MAGEB17 melanoma antigen family B17 1.008
TCP11L1 t-complex 11, testis-specific-like 1 1.001