Extension of Telomeres Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-180786
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Genes

51 proteins participating in the Extension of Telomeres pathway from the Reactome Pathways 2024 dataset.

Symbol Name
ACD adrenocortical dysplasia homolog (mouse)
ANKRD28 ankyrin repeat domain 28
BLM Bloom syndrome, RecQ helicase-like
CCNA1 cyclin A1
CCNA2 cyclin A2
CDK2 cyclin-dependent kinase 2
CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
CHTF8 CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
CTC1 CTS telomere maintenance complex component 1
DKC1 dyskeratosis congenita 1, dyskerin
DNA2 DNA replication helicase/nuclease 2
DSCC1 DNA replication and sister chromatid cohesion 1
FEN1 flap structure-specific endonuclease 1
GAR1 GAR1 ribonucleoprotein
LIG1 ligase I, DNA, ATP-dependent
NHP2 NHP2 ribonucleoprotein
NOP10 NOP10 ribonucleoprotein
PCNA proliferating cell nuclear antigen
PIF1 PIF1 5'-to-3' DNA helicase
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLD2 polymerase (DNA directed), delta 2, accessory subunit
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POT1 protection of telomeres 1
PPP6C protein phosphatase 6, catalytic subunit
PPP6R3 protein phosphatase 6, regulatory subunit 3
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRIM2 primase, DNA, polypeptide 2 (58kDa)
RFC1 replication factor C (activator 1) 1, 145kDa
RFC2 replication factor C (activator 1) 2, 40kDa
RFC3 replication factor C (activator 1) 3, 38kDa
RFC4 replication factor C (activator 1) 4, 37kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
RPA1 replication protein A1, 70kDa
RPA2 replication protein A2, 32kDa
RPA3 replication protein A3, 14kDa
RTEL1 regulator of telomere elongation helicase 1
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor
STN1 STN1 subunit of CST complex
TEN1 TEN1 CST complex subunit
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERF2 telomeric repeat binding factor 2
TERF2IP telomeric repeat binding factor 2, interacting protein
TERT telomerase reverse transcriptase
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
WRAP53 WD repeat containing, antisense to TP53
WRN Werner syndrome, RecQ helicase-like