Extravasation of Diagnostic and Therapeutic Materials Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D005119
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Genes

313 genes/proteins associated with the disease Extravasation of Diagnostic and Therapeutic Materials from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
AMN amnion associated transmembrane protein 2.88009
IL1RN interleukin 1 receptor antagonist 2.88009
BDKRB2 bradykinin receptor B2 2.88009
TAC1 tachykinin, precursor 1 2.88009
NR1H4 nuclear receptor subfamily 1, group H, member 4 2.88009
KNG1 kininogen 1 2.88009
IL6 interleukin 6 2.29889
FOS FBJ murine osteosarcoma viral oncogene homolog 2.27188
NOS2 nitric oxide synthase 2, inducible 2.21917
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.21114
TNF tumor necrosis factor 2.21068
IL1B interleukin 1, beta 2.20166
BAX BCL2-associated X protein 2.18428
BCL2 B-cell CLL/lymphoma 2 2.18282
CAT catalase 2.15356
MAPK3 mitogen-activated protein kinase 3 2.10941
CXCL8 chemokine (C-X-C motif) ligand 8 2.07301
IFNG interferon, gamma 2.0562
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.05269
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.01856
COL1A1 collagen, type I, alpha 1 2.01814
MAPK1 mitogen-activated protein kinase 1 2.01458
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.99581
EGR1 early growth response 1 1.99265
CCL2 chemokine (C-C motif) ligand 2 1.97912
HMOX1 heme oxygenase 1 1.97684
FASLG Fas ligand (TNF superfamily, member 6) 1.95375
IL1A interleukin 1, alpha 1.92626
TP53 tumor protein p53 1.92391
IL2 interleukin 2 1.92312
MPO myeloperoxidase 1.912
IL12B interleukin 12B 1.89715
IL10 interleukin 10 1.89666
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.88964
FAS Fas cell surface death receptor 1.86323
EDN1 endothelin 1 1.85081
CALCA calcitonin-related polypeptide alpha 1.83753
GSTP1 glutathione S-transferase pi 1 1.83113
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.82272
NOS3 nitric oxide synthase 3 (endothelial cell) 1.82202
IL4 interleukin 4 1.82046
NPPA natriuretic peptide A 1.80849
MAPK8 mitogen-activated protein kinase 8 1.80454
SOD2 superoxide dismutase 2, mitochondrial 1.80019
MMP9 matrix metallopeptidase 9 1.79408
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.78778
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.78052
POR P450 (cytochrome) oxidoreductase 1.7757
TGFB1 transforming growth factor, beta 1 1.77472
BIRC3 baculoviral IAP repeat containing 3 1.7623
ICAM1 intercellular adhesion molecule 1 1.75221
NGF nerve growth factor (beta polypeptide) 1.74641
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.74401
JUN jun proto-oncogene 1.74159
TLR4 toll-like receptor 4 1.72988
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.71544
TIMP1 TIMP metallopeptidase inhibitor 1 1.69888
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.69383
GADD45A growth arrest and DNA-damage-inducible, alpha 1.68358
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.68295
MAPK14 mitogen-activated protein kinase 14 1.65753
HSPA8 heat shock 70kDa protein 8 1.65249
MMP1 matrix metallopeptidase 1 1.65113
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.63966
STAT1 signal transducer and activator of transcription 1, 91kDa 1.63698
CXCR4 chemokine (C-X-C motif) receptor 4 1.63518
CLU clusterin 1.63428
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.63272
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.61782
SOD1 superoxide dismutase 1, soluble 1.61483
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.61413
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.60851
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.59802
MMP2 matrix metallopeptidase 2 1.58561
CYCS cytochrome c, somatic 1.56214
CXCL5 chemokine (C-X-C motif) ligand 5 1.55304
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.54986
IL18 interleukin 18 1.54669
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.54596
BCL2L1 BCL2-like 1 1.53258
F3 coagulation factor III (thromboplastin, tissue factor) 1.53209
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.5284
VEGFA vascular endothelial growth factor A 1.5113
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.50903
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.50751
CXCL10 chemokine (C-X-C motif) ligand 10 1.50095
AVP arginine vasopressin 1.50069
KLF2 Kruppel-like factor 2 1.49967
PARP1 poly (ADP-ribose) polymerase 1 1.49432
MAPK9 mitogen-activated protein kinase 9 1.48967
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.4889
F2 coagulation factor II (thrombin) 1.48813
CCL3 chemokine (C-C motif) ligand 3 1.4871
CCL20 chemokine (C-C motif) ligand 20 1.48556
REN renin 1.48505
VCAM1 vascular cell adhesion molecule 1 1.48299
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.4794
ALB albumin 1.47838
GSTM1 glutathione S-transferase mu 1 1.47038
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.46909
PPARG peroxisome proliferator-activated receptor gamma 1.46754
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.46515
NPPB natriuretic peptide B 1.45723
MAP2K1 mitogen-activated protein kinase kinase 1 1.45617
CFLAR CASP8 and FADD-like apoptosis regulator 1.45115
CREB1 cAMP responsive element binding protein 1 1.45063
GPX1 glutathione peroxidase 1 1.44817
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.44735
APOE apolipoprotein E 1.43864
MMP13 matrix metallopeptidase 13 1.42321
BDKRB1 bradykinin receptor B1 1.42156
DDIT3 DNA-damage-inducible transcript 3 1.42156
KLF4 Kruppel-like factor 4 (gut) 1.42156
PLAUR plasminogen activator, urokinase receptor 1.41775
IL12A interleukin 12A 1.41775
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.41667
DUSP1 dual specificity phosphatase 1 1.41396
NFE2L2 nuclear factor, erythroid 2-like 2 1.40925
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.4026
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.39757
MMP3 matrix metallopeptidase 3 1.39702
FOSL1 FOS-like antigen 1 1.39366
CP ceruloplasmin (ferroxidase) 1.38527
IL13 interleukin 13 1.38043
PLAU plasminogen activator, urokinase 1.38043
RB1 retinoblastoma 1 1.3793
NOS1 nitric oxide synthase 1 (neuronal) 1.37246
SELL selectin L 1.36763
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.36619
ATF3 activating transcription factor 3 1.36447
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.36019
TACR1 tachykinin receptor 1 1.35242
POMC proopiomelanocortin 1.34024
CCL5 chemokine (C-C motif) ligand 5 1.34024
CTGF connective tissue growth factor 1.33909
TLR2 toll-like receptor 2 1.33791
GH1 growth hormone 1 1.33405
CRH corticotropin releasing hormone 1.33199
IL5 interleukin 5 1.33169
BAD BCL2-associated agonist of cell death 1.33052
SRGN serglycin 1.32846
GSK3B glycogen synthase kinase 3 beta 1.32667
GJA1 gap junction protein, alpha 1, 43kDa 1.32458
LEP leptin 1.32339
COL3A1 collagen, type III, alpha 1 1.32044
PPARA peroxisome proliferator-activated receptor alpha 1.32015
SPP1 secreted phosphoprotein 1 1.31807
HRAS Harvey rat sarcoma viral oncogene homolog 1.31626
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.31059
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.30788
RYR2 ryanodine receptor 2 (cardiac) 1.30758
EGFR epidermal growth factor receptor 1.30635
S100A4 S100 calcium binding protein A4 1.29781
HSPA1A heat shock 70kDa protein 1A 1.29194
LPL lipoprotein lipase 1.29194
HSPB1 heat shock 27kDa protein 1 1.29072
G0S2 G0/G1 switch 2 1.29011
ACTB actin, beta 1.2895
C3 complement component 3 1.2861
CAV1 caveolin 1, caveolae protein, 22kDa 1.2861
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.28425
CD14 CD14 molecule 1.28425
NQO1 NAD(P)H dehydrogenase, quinone 1 1.28395
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.27626
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.26886
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.26638
THY1 Thy-1 cell surface antigen 1.26267
PPP1R12A protein phosphatase 1, regulatory subunit 12A 1.26267
GFAP glial fibrillary acidic protein 1.26113
CTSL cathepsin L 1.2596
PCNA proliferating cell nuclear antigen 1.25899
TBX21 T-box 21 1.25619
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 1.24275
GSTM2 glutathione S-transferase mu 2 (muscle) 1.23488
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.22948
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.22948
LITAF lipopolysaccharide-induced TNF factor 1.22112
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.21337
TOP2A topoisomerase (DNA) II alpha 170kDa 1.21304
PLAT plasminogen activator, tissue 1.21304
BCL6 B-cell CLL/lymphoma 6 1.21206
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.21011
CD83 CD83 molecule 1.20913
BIRC2 baculoviral IAP repeat containing 2 1.20751
MIR150 microRNA 150 1.20229
CSF3 colony stimulating factor 3 (granulocyte) 1.19999
TXNIP thioredoxin interacting protein 1.19999
SRXN1 sulfiredoxin 1 1.19999
ANXA1 annexin A1 1.19802
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.19509
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.19477
COL4A1 collagen, type IV, alpha 1 1.19213
TGFB2 transforming growth factor, beta 2 1.18849
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 1.18193
MMP8 matrix metallopeptidase 8 1.17761
CCNB1 cyclin B1 1.17268
XBP1 X-box binding protein 1 1.17268
TRIB3 tribbles pseudokinase 3 1.169
BTG2 BTG family, member 2 1.16567
HSF1 heat shock transcription factor 1 1.16368
TGFB3 transforming growth factor, beta 3 1.16368
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.15729
BTG1 B-cell translocation gene 1, anti-proliferative 1.15357
CD5 CD5 molecule 1.15357
TIMP2 TIMP metallopeptidase inhibitor 2 1.15189
AHR aryl hydrocarbon receptor 1.15089
CCL22 chemokine (C-C motif) ligand 22 1.14954
APP amyloid beta (A4) precursor protein 1.14954
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 1.14404
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 1.14404
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.14234
CDK2 cyclin-dependent kinase 2 1.13997
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.13724
FN1 fibronectin 1 1.13518
EEF2 eukaryotic translation elongation factor 2 1.13484
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.13007
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 1.12737
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.12564
BDNF brain-derived neurotrophic factor 1.12254
CTH cystathionine gamma-lyase 1.12151
TEK TEK tyrosine kinase, endothelial 1.12048
INS insulin 1.11707
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 1.11707
IGF1 insulin-like growth factor 1 (somatomedin C) 1.11571
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 1.1136
IFNGR1 interferon gamma receptor 1 1.11325
KLF6 Kruppel-like factor 6 1.11046
PARK7 parkinson protein 7 1.11011
PRNP prion protein 1.10838
PRKCA protein kinase C, alpha 1.10838
S100A9 S100 calcium binding protein A9 1.10838
GSTT1 glutathione S-transferase theta 1 1.10527
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.10424
PF4 platelet factor 4 1.10353
MAP3K8 mitogen-activated protein kinase kinase kinase 8 1.10353
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.09998
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.09366
EGR3 early growth response 3 1.09366
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.0919
RGS2 regulator of G-protein signaling 2 1.0919
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.08975
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.08797
S100A8 S100 calcium binding protein A8 1.08797
RGS16 regulator of G-protein signaling 16 1.08726
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.08655
APOA1 apolipoprotein A-I 1.08655
EPO erythropoietin 1.08407
BIRC5 baculoviral IAP repeat containing 5 1.08231
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 1.08161
LBP lipopolysaccharide binding protein 1.08126
ISG15 ISG15 ubiquitin-like modifier 1.0784
CYBB cytochrome b-245, beta polypeptide 1.07804
VIM vimentin 1.07696
RETN resistin 1.07553
FKBP4 FK506 binding protein 4, 59kDa 1.07518
GSR glutathione reductase 1.07518
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 1.07376
TGM2 transglutaminase 2 1.07234
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.07234
TFRC transferrin receptor 1.07163
VWF von Willebrand factor 1.06952
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 1.06952
TXN thioredoxin 1.06881
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.06661
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.06515
IRS1 insulin receptor substrate 1 1.06479
STIP1 stress-induced phosphoprotein 1 1.0637
ANXA4 annexin A4 1.0637
ADIPOQ adiponectin, C1Q and collagen domain containing 1.06116
TRPA1 transient receptor potential cation channel, subfamily A, member 1 1.05828
CYP3A cytochrome P450, family 3, subfamily A 1.05828
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.05535
NTF3 neurotrophin 3 1.05535
NPY neuropeptide Y 1.05386
GPX3 glutathione peroxidase 3 1.05386
HSPA1B heat shock 70kDa protein 1B 1.052
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.05126
BAK1 BCL2-antagonist/killer 1 1.05015
TH tyrosine hydroxylase 1.04941
IL1RL1 interleukin 1 receptor-like 1 1.04427
IL1R2 interleukin 1 receptor, type II 1.04126
CRYAB crystallin, alpha B 1.04126
SESN2 sestrin 2 1.03864
PHGDH phosphoglycerate dehydrogenase 1.03604
ACTA2 actin, alpha 2, smooth muscle, aorta 1.0353
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 1.03493
TTN titin 1.03456
EVI2A ecotropic viral integration site 2A 1.03456
E2F1 E2F transcription factor 1 1.03419
MMP12 matrix metallopeptidase 12 1.03382
NCF2 neutrophil cytosolic factor 2 1.03345
GUSB glucuronidase, beta 1.03345
CCND1 cyclin D1 1.03308
CD38 CD38 molecule 1.03084
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.03084
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 1.03009
EGF epidermal growth factor 1.02933
GCLC glutamate-cysteine ligase, catalytic subunit 1.02896
SP1 Sp1 transcription factor 1.02896
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 1.02821
ATF4 activating transcription factor 4 1.02746
FSCN1 fascin actin-bundling protein 1 1.02559
FABP3 fatty acid binding protein 3, muscle and heart 1.02559
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.02336
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.02188
E2F3 E2F transcription factor 3 1.02114
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.02114
FADD Fas (TNFRSF6)-associated via death domain 1.02077
GCLM glutamate-cysteine ligase, modifier subunit 1.01966
CD44 CD44 molecule (Indian blood group) 1.0189
FABP4 fatty acid binding protein 4, adipocyte 1.01587
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.01587
THRSP thyroid hormone responsive 1.01324