Exudative Age-Related Macular Degeneration Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0271084
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Genes

148 genes associated with the disease Exudative Age-Related Macular Degeneration in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACAD10 acyl-CoA dehydrogenase family, member 10
ACE angiotensin I converting enzyme
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
AMD1 adenosylmethionine decarboxylase 1
ANGPT2 angiopoietin 2
ANGPTL4 angiopoietin-like 4
ANXA2 annexin A2
APOE apolipoprotein E
ARHGAP21 Rho GTPase activating protein 21
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARMS2 age-related maculopathy susceptibility 2
ARSF arylsulfatase F
AURKA aurora kinase A
B3GLCT beta 3-glucosyltransferase
BMP6 bone morphogenetic protein 6
C10ORF88 chromosome 10 open reading frame 88
C2 complement component 2
C3 complement component 3
C9 complement component 9
CALCR calcitonin receptor
CALR calreticulin
CCL2 chemokine (C-C motif) ligand 2
CCR2 chemokine (C-C motif) receptor 2
CD36 CD36 molecule (thrombospondin receptor)
CD93 CD93 molecule
CETP cholesteryl ester transfer protein, plasma
CFB complement factor B
CFH complement factor H
CFHR5 complement factor H-related 5
CFI complement factor I
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CIAO3 cytosolic iron-sulfur assembly component 3
CNN2 calponin 2
COL1A2 collagen, type I, alpha 2
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL8A1 collagen, type VIII, alpha 1
CRP C-reactive protein, pentraxin-related
CRYAB crystallin, alpha B
CSF1R colony stimulating factor 1 receptor
CST3 cystatin C
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
DDIT4 DNA-damage-inducible transcript 4
DKK1 dickkopf WNT signaling pathway inhibitor 1
EGF epidermal growth factor
EGLN1 egl-9 family hypoxia-inducible factor 1
ELN elastin
ELOVL4 ELOVL fatty acid elongase 4
EPO erythropoietin
EXOC3L2 exocyst complex component 3-like 2
EXOC5 exocyst complex component 5
FGD6 FYVE, RhoGEF and PH domain containing 6
FGF21 fibroblast growth factor 21
FLT1 fms-related tyrosine kinase 1
FPR1 formyl peptide receptor 1
FSHR follicle stimulating hormone receptor
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FZD4 frizzled class receptor 4
GDF6 growth differentiation factor 6
GPX3 glutathione peroxidase 3
GREM1 gremlin 1, DAN family BMP antagonist
GSTK1 glutathione S-transferase kappa 1
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GSTZ1 glutathione S-transferase zeta 1
HPGDS hematopoietic prostaglandin D synthase
HTRA1 HtrA serine peptidase 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1
IL1B interleukin 1, beta
IL6 interleukin 6
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KCNT2 potassium channel, sodium activated subfamily T, member 2
KDR kinase insert domain receptor
LHFP lipoma HMGIC fusion partner
LIPC lipase, hepatic
MARK4 MAP/microtubule affinity-regulating kinase 4
MASP2 mannan-binding lectin serine peptidase 2
MCAM melanoma cell adhesion molecule
MMP1 matrix metallopeptidase 1
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NCAM1 neural cell adhesion molecule 1
NELFE negative elongation factor complex member E
NOS3 nitric oxide synthase 3 (endothelial cell)
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRP1 neuropilin 1
PAEP progestagen-associated endometrial protein
PBX2 pre-B-cell leukemia homeobox 2
PGF placental growth factor
PILRA paired immunoglobin-like type 2 receptor alpha
PLA2G12A phospholipase A2, group XIIA
PLEK pleckstrin
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLXNA2 plexin A2
PNPLA2 patatin-like phospholipase domain containing 2
PON1 paraoxonase 1
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PTN pleiotrophin
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD51B RAD51 paralog B
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RORA RAR-related orphan receptor A
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8
SLC44A4 solute carrier family 44, member 4
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SMAD4 SMAD family member 4
SOD2 superoxide dismutase 2, mitochondrial
SRPK2 SRSF protein kinase 2
SRSF1 serine/arginine-rich splicing factor 1
STK19 serine/threonine kinase 19
SYN3 synapsin III
TEK TEK tyrosine kinase, endothelial
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
THY1 Thy-1 cell surface antigen
TIMP3 TIMP metallopeptidase inhibitor 3
TLR3 toll-like receptor 3
TMEM97 transmembrane protein 97
TNF tumor necrosis factor
TNR tenascin R
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TRPM3 transient receptor potential cation channel, subfamily M, member 3
UNC93B1 unc-93 homolog B1 (C. elegans)
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
VLDLR very low density lipoprotein receptor
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae)
VWF von Willebrand factor
ZFP36 ZFP36 ring finger protein