Ezetimibe Gene Set

Dataset HMDB Metabolites of Enzymes
Category physical interactions
Type metabolite
Description A beta-lactam that is azetidin-2-one which is substituted at 1, 3, and 4 by p-fluorophenyl, 3-(p-fluorophenyl)-3-hydroxypropyl, and 4-hydroxyphenyl groups, respectively (the 3R,3'S,4S enantiomer). (Chemical Entities of Biological Interest Ontology, CHEBI_49040)
External Link http://www.hmdb.ca/metabolites/HMDB15108
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Genes

11 interacting proteins for the Ezetimibe metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ANPEP alanyl (membrane) aminopeptidase
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
NPC1L1 NPC1-like 1
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SOAT1 sterol O-acyltransferase 1
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7