F10 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description coagulation factor X|This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2159)
External Link https://ncbi.nlm.nih.gov/gene/2159
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Genes

497 genes differentially expressed following the F10 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MMP12 matrix metallopeptidase 12 0.0144393
XPO7 exportin 7 0.0142128
SRGN serglycin 0.0141834
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.0127988
BPHL biphenyl hydrolase-like (serine hydrolase) 0.012438
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.01112
DAXX death-domain associated protein 0.0109918
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0108723
CST7 cystatin F (leukocystatin) 0.0102336
KDM5D lysine (K)-specific demethylase 5D 0.0100742
CXCL8 chemokine (C-X-C motif) ligand 8 0.0100739
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.0100213
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.00991989
S100A7 S100 calcium binding protein A7 0.00979219
ZNF395 zinc finger protein 395 0.00949623
WDR7 WD repeat domain 7 0.00940072
CSRP2 cysteine and glycine-rich protein 2 0.00918868
GRB7 growth factor receptor-bound protein 7 0.00911865
S100A9 S100 calcium binding protein A9 0.00879781
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.00853123
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00851874
CRELD2 cysteine-rich with EGF-like domains 2 0.00847644
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00831951
AQP3 aquaporin 3 (Gill blood group) 0.00820328
CHIC2 cysteine-rich hydrophobic domain 2 0.00820218
CALB1 calbindin 1, 28kDa 0.00804118
TUBB2A tubulin, beta 2A class IIa 0.00801116
LAMP3 lysosomal-associated membrane protein 3 0.00777734
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.00768465
MAP7 microtubule-associated protein 7 0.00768035
TARP TCR gamma alternate reading frame protein 0.00766249
SLAMF7 SLAM family member 7 0.00761826
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.00756078
NQO2 NAD(P)H dehydrogenase, quinone 2 0.00748678
SLA Src-like-adaptor 0.00747416
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00744968
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.00718526
SIK1 salt-inducible kinase 1 0.00713289
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 0.00708248
BPGM 2,3-bisphosphoglycerate mutase 0.00706152
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.00704311
PRF1 perforin 1 (pore forming protein) 0.00690376
HLA-DRA major histocompatibility complex, class II, DR alpha 0.00683302
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00680263
LCN2 lipocalin 2 0.00679913
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.00678299
TAPBP TAP binding protein (tapasin) 0.00675377
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.00674883
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00671955
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 0.00670911
WFDC1 WAP four-disulfide core domain 1 0.00666827
OPTN optineurin 0.00666762
CYTIP cytohesin 1 interacting protein 0.00664855
STOM stomatin 0.00664599
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.00661172
PCCB propionyl CoA carboxylase, beta polypeptide 0.00660891
HAL histidine ammonia-lyase 0.00659576
LEPROTL1 leptin receptor overlapping transcript-like 1 0.00653629
NKG7 natural killer cell granule protein 7 0.00651392
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00649667
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) 0.00646353
TACSTD2 tumor-associated calcium signal transducer 2 0.00645163
AQP9 aquaporin 9 0.00642425
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.00637644
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 0.00636372
LTBP1 latent transforming growth factor beta binding protein 1 0.00634011
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.00633388
VIM vimentin 0.00632577
S100A8 S100 calcium binding protein A8 0.00629849
IL1B interleukin 1, beta 0.00627396
IL7R interleukin 7 receptor 0.00627066
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.00623736
ARG1 arginase 1 0.00623397
ECI2 enoyl-CoA delta isomerase 2 0.00622135
KRT1 keratin 1, type II 0.0061666
NVL nuclear VCP-like 0.00614033
IFITM1 interferon induced transmembrane protein 1 0.00613704
ACOT7 acyl-CoA thioesterase 7 0.00613338
IL1RN interleukin 1 receptor antagonist 0.00611809
YPEL5 yippee-like 5 (Drosophila) 0.00605554
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.00604956
MFAP3L microfibrillar-associated protein 3-like 0.00603355
FBXO28 F-box protein 28 0.00602571
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00600708
CD27 CD27 molecule 0.00599625
DDAH2 dimethylarginine dimethylaminohydrolase 2 0.00596703
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 0.00594688
BAMBI BMP and activin membrane-bound inhibitor 0.00589842
CD8A CD8a molecule 0.00589277
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.00588186
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 0.00583945
ASB13 ankyrin repeat and SOCS box containing 13 0.00578107
MRS2 MRS2 magnesium transporter 0.00576913
SAMHD1 SAM domain and HD domain 1 0.00575007
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 0.00572141
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.0057179
RGCC regulator of cell cycle 0.00566401
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.00565534
AMACR alpha-methylacyl-CoA racemase 0.00565517
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00565134
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.00564402
TAL1 T-cell acute lymphocytic leukemia 1 0.00564342
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.00563227
CCL5 chemokine (C-C motif) ligand 5 0.00562419
PODXL podocalyxin-like 0.00561903
PTGES prostaglandin E synthase 0.00560687
TPST2 tyrosylprotein sulfotransferase 2 0.00559525
CNIH4 cornichon family AMPA receptor auxiliary protein 4 0.00558339
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 0.00554277
SLCO4C1 solute carrier organic anion transporter family, member 4C1 0.00551814
WNK1 WNK lysine deficient protein kinase 1 0.00551737
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 0.00549472
GGCT gamma-glutamylcyclotransferase 0.00548478
FAR2 fatty acyl CoA reductase 2 0.00546694
SOSTDC1 sclerostin domain containing 1 0.00546212
CTSW cathepsin W 0.00546103
DEFB1 defensin, beta 1 0.00545026
GLYAT glycine-N-acyltransferase 0.00544535
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.00544498
SPRR2B small proline-rich protein 2B 0.00543769
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.00542414
ZIC1 Zic family member 1 0.0054226
GREM1 gremlin 1, DAN family BMP antagonist 0.00541251
CBR4 carbonyl reductase 4 0.00541011
PDHX pyruvate dehydrogenase complex, component X 0.0054058
CD81 CD81 molecule 0.00540325
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.00537435
ZBTB18 zinc finger and BTB domain containing 18 0.00536116
CDYL chromodomain protein, Y-like 0.00534368
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00533027
GPM6A glycoprotein M6A 0.00531526
ABI1 abl-interactor 1 0.00530778
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 0.00530581
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.00530349
PDE4D phosphodiesterase 4D, cAMP-specific 0.00529946
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 0.00528374
AKAP8 A kinase (PRKA) anchor protein 8 0.00527215
RCAN1 regulator of calcineurin 1 0.00525884
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 0.00523002
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.00522636
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.00520821
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.00519988
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00519366
CD2 CD2 molecule 0.00518597
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.0051823
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.0051782
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.00515844
BCL2A1 BCL2-related protein A1 0.00515698
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.00514315
CCDC6 coiled-coil domain containing 6 0.00512828
LAPTM5 lysosomal protein transmembrane 5 0.00511796
CD52 CD52 molecule 0.00511678
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 0.00511038
VNN1 vanin 1 0.00509607
SSR1 signal sequence receptor, alpha 0.00509224
PCGF2 polycomb group ring finger 2 0.00508832
HSPA13 heat shock protein 70kDa family, member 13 0.00507884
ACP3 acid phosphatase 3 0.00507364
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.00507356
ITK IL2-inducible T-cell kinase 0.00507203
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.00507194
MAP2K6 mitogen-activated protein kinase kinase 6 0.00506252
PDE4B phosphodiesterase 4B, cAMP-specific 0.00503622
CFB complement factor B 0.00503452
ELP3 elongator acetyltransferase complex subunit 3 0.00502439
KRT13 keratin 13, type I 0.00501926
THEMIS2 thymocyte selection associated family member 2 0.00501038
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.00500987
RBM8A RNA binding motif protein 8A 0.00500063
TPP1 tripeptidyl peptidase I 0.00499877
UBXN7 UBX domain protein 7 0.00498568
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 0.00498154
VWA5A von Willebrand factor A domain containing 5A 0.00497269
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 0.00497063
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 0.00495123
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.00494102
FOXC1 forkhead box C1 0.00492021
S100A12 S100 calcium binding protein A12 0.00490598
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 0.00490146
PSAT1 phosphoserine aminotransferase 1 0.00489865
CD163 CD163 molecule 0.00489538
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00488536
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 0.00488134
DEFB4A defensin, beta 4A 0.00486473
RHCG Rh family, C glycoprotein 0.00485478
HCK HCK proto-oncogene, Src family tyrosine kinase 0.00485057
GLO1 glyoxalase I 0.00484456
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.0048439
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.00484282
NIPSNAP1 nipsnap homolog 1 (C. elegans) 0.00484277
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.00483013
LXN latexin 0.00482619
KAT7 K(lysine) acetyltransferase 7 0.00480996
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 0.00479254
AHNAK2 AHNAK nucleoprotein 2 0.00478204
MMUT methylmalonyl-CoA mutase 0.0047818
CNPY3 canopy FGF signaling regulator 3 0.00478159
PI3 peptidase inhibitor 3, skin-derived 0.00478126
SHROOM2 shroom family member 2 0.00478045
KIAA0125 KIAA0125 0.00477987
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.0047518
TYRP1 tyrosinase-related protein 1 0.00474789
FGGY FGGY carbohydrate kinase domain containing 0.00474441
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00474213
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00474127
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 0.00473913
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 0.00472936
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.00472824
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 0.0047262
CLCN3 chloride channel, voltage-sensitive 3 0.00472478
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 0.00471901
BIN2 bridging integrator 2 0.00471071
KDSR 3-ketodihydrosphingosine reductase 0.00469785
CTBP2 C-terminal binding protein 2 0.0046959
GIMAP4 GTPase, IMAP family member 4 0.00469182
GPR137B G protein-coupled receptor 137B 0.00468525
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.00468167
PITRM1 pitrilysin metallopeptidase 1 0.00466732
GDI2 GDP dissociation inhibitor 2 0.00466476
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.00466398
ADM adrenomedullin 0.00465866
HSP90B2P heat shock protein 90kDa beta (Grp94), member 2, pseudogene 0.00465751
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.00465503
TMCC2 transmembrane and coiled-coil domain family 2 0.00464589
PLAT plasminogen activator, tissue 0.00464362
ECM1 extracellular matrix protein 1 0.00464243
LOX lysyl oxidase 0.00463484
SIRT5 sirtuin 5 0.00463235
IL2RB interleukin 2 receptor, beta 0.00462423
LST1 leukocyte specific transcript 1 0.00461906
STC1 stanniocalcin 1 0.00461218
USP9Y ubiquitin specific peptidase 9, Y-linked 0.0046097
ABHD17B abhydrolase domain containing 17B 0.00460615
FOSL2 FOS-like antigen 2 0.00459737
FCMR Fc fragment of IgM receptor 0.00459001
PGM3 phosphoglucomutase 3 0.00458037
FOXO1 forkhead box O1 0.00457567
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 0.00457235
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.00457152
KLK13 kallikrein-related peptidase 13 0.00456824
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.00456461
FYB1 FYN binding protein 1 0.00456446
LOR loricrin 0.00456135
GMNN geminin, DNA replication inhibitor 0.00455173
MVP major vault protein 0.00454698
UPK1B uroplakin 1B 0.0045328
TMPRSS11D transmembrane protease, serine 11D 0.00452034
HCP5 HLA complex P5 (non-protein coding) 0.00450647

decreased expression

Symbol Name Standardized Value
PEG3 paternally expressed 3 -0.0180153
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.0175645
DLK1 delta-like 1 homolog (Drosophila) -0.0167381
SSBP2 single-stranded DNA binding protein 2 -0.0153481
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.0152953
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.0141563
IGFBP5 insulin-like growth factor binding protein 5 -0.0137475
ALB albumin -0.0137218
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0136398
CPE carboxypeptidase E -0.0134102
KRT19 keratin 19, type I -0.0128694
AMIGO2 adhesion molecule with Ig-like domain 2 -0.0117271
MGP matrix Gla protein -0.0115517
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.0113321
SCG5 secretogranin V -0.0110017
LYN LYN proto-oncogene, Src family tyrosine kinase -0.0109725
CCND1 cyclin D1 -0.0108373
THBS4 thrombospondin 4 -0.0107845
MMP7 matrix metallopeptidase 7 -0.0105826
SFRP1 secreted frizzled-related protein 1 -0.0105029
MT1E metallothionein 1E -0.0103025
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.0101733
PLK2 polo-like kinase 2 -0.010125
OGN osteoglycin -0.0101176
XIC X chromosome inactivation center -0.0100527
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.0100498
C7 complement component 7 -0.0100405
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.0100363
RHOBTB3 Rho-related BTB domain containing 3 -0.00989378
TGFBI transforming growth factor, beta-induced, 68kDa -0.00986301
PEG10 paternally expressed 10 -0.00985948
ISL1 ISL LIM homeobox 1 -0.00985357
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00956251
SOBP sine oculis binding protein homolog (Drosophila) -0.00946837
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00916894
SNAI2 snail family zinc finger 2 -0.00916807
KRT7 keratin 7, type II -0.00914597
FXYD6 FXYD domain containing ion transport regulator 6 -0.00908043
KRT18 keratin 18, type I -0.00906855
CDC20 cell division cycle 20 -0.00906015
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.00902416
AKR1C1 aldo-keto reductase family 1, member C1 -0.0090168
KRT8 keratin 8, type II -0.00878709
SPARCL1 SPARC-like 1 (hevin) -0.00877792
S100P S100 calcium binding protein P -0.00871372
NPTX2 neuronal pentraxin II -0.00862609
TSPAN5 tetraspanin 5 -0.00860398
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00858594
AKR1C2 aldo-keto reductase family 1, member C2 -0.00827021
FHL1 four and a half LIM domains 1 -0.00825673
S100A4 S100 calcium binding protein A4 -0.00821476
COMP cartilage oligomeric matrix protein -0.00808473
AGR2 anterior gradient 2 -0.00805689
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.0079769
EFNB2 ephrin-B2 -0.00792799
TPSAB1 tryptase alpha/beta 1 -0.0078274
PDGFD platelet derived growth factor D -0.00781217
MFAP5 microfibrillar associated protein 5 -0.00774951
DYNLL1 dynein, light chain, LC8-type 1 -0.00769706
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.00767952
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 -0.00767274
ARID4A AT rich interactive domain 4A (RBP1-like) -0.00766558
METTL7A methyltransferase like 7A -0.00766374
CAV1 caveolin 1, caveolae protein, 22kDa -0.00765655
AKR1C3 aldo-keto reductase family 1, member C3 -0.0076336
TSPAN7 tetraspanin 7 -0.00761765
LMO3 LIM domain only 3 (rhombotin-like 2) -0.00756724
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00755683
CST3 cystatin C -0.00750163
COL14A1 collagen, type XIV, alpha 1 -0.00749832
TYMS thymidylate synthetase -0.00747854
BEX1 brain expressed, X-linked 1 -0.00746383
RRAGA Ras-related GTP binding A -0.00744857
KRT23 keratin 23, type I -0.00740643
SFRP4 secreted frizzled-related protein 4 -0.00735182
PLPP3 phospholipid phosphatase 3 -0.00734914
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 -0.00725131
CTSE cathepsin E -0.00725048
SLIT2 slit homolog 2 (Drosophila) -0.00722129
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.00721832
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.00718296
RUFY3 RUN and FYVE domain containing 3 -0.00717467
XYLT1 xylosyltransferase I -0.00716499
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00715294
GAS1 growth arrest-specific 1 -0.00713937
APOA1 apolipoprotein A-I -0.00713291
SCGB1D2 secretoglobin, family 1D, member 2 -0.00708404
PCDH17 protocadherin 17 -0.00704131
MEIS2 Meis homeobox 2 -0.00703503
DEPTOR DEP domain containing MTOR-interacting protein -0.0070225
HHEX hematopoietically expressed homeobox -0.00697246
TLE4 transducin-like enhancer of split 4 -0.00696125
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00695241
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00692134
APOD apolipoprotein D -0.00691504
MLXIP MLX interacting protein -0.00691244
LDB2 LIM domain binding 2 -0.00689337
EIF5A eukaryotic translation initiation factor 5A -0.00683513
ISLR immunoglobulin superfamily containing leucine-rich repeat -0.00676994
PRSS3 protease, serine, 3 -0.00675988
H1-0 H1.0 linker histone -0.00675732
SCGB2A1 secretoglobin, family 2A, member 1 -0.00663368
LAMP5 lysosomal-associated membrane protein family, member 5 -0.00662533
GPX2 glutathione peroxidase 2 -0.00661571
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00661322
ANXA10 annexin A10 -0.0066115
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.0065686
JAM3 junctional adhesion molecule 3 -0.00656397
APOB apolipoprotein B -0.0065541
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.0065124
ORM1 orosomucoid 1 -0.00649905
MPPED2 metallophosphoesterase domain containing 2 -0.0064938
SLC38A1 solute carrier family 38, member 1 -0.00648889
ISG15 ISG15 ubiquitin-like modifier -0.00648621
AMBP alpha-1-microglobulin/bikunin precursor -0.00648276
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.00647828
APOH apolipoprotein H (beta-2-glycoprotein I) -0.00647661
F3 coagulation factor III (thromboplastin, tissue factor) -0.00644856
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00642657
MAGED1 melanoma antigen family D1 -0.00641736
PLVAP plasmalemma vesicle associated protein -0.00641392
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.00636853
NID2 nidogen 2 (osteonidogen) -0.00634006
ANXA5 annexin A5 -0.00630644
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00628118
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.00627343
CRABP2 cellular retinoic acid binding protein 2 -0.00625465
LMNA lamin A/C -0.00624102
DGKD diacylglycerol kinase, delta 130kDa -0.0062396
AEBP1 AE binding protein 1 -0.00622708
PLIN2 perilipin 2 -0.00619948
REEP1 receptor accessory protein 1 -0.00611402
CYTH1 cytohesin 1 -0.00606372
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.00605621
ABAT 4-aminobutyrate aminotransferase -0.0060392
PON3 paraoxonase 3 -0.00602806
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -0.00601393
S100A2 S100 calcium binding protein A2 -0.00600262
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -0.00599959
SYT1 synaptotagmin I -0.00597882
RXYLT1 ribitol xylosyltransferase 1 -0.00595999
TFF2 trefoil factor 2 -0.00595169
KANK2 KN motif and ankyrin repeat domains 2 -0.00594194
PPARG peroxisome proliferator-activated receptor gamma -0.00593545
OLFML3 olfactomedin-like 3 -0.00591094
LPAR6 lysophosphatidic acid receptor 6 -0.00589319
SCGB2A2 secretoglobin, family 2A, member 2 -0.00589307
RGS5 regulator of G-protein signaling 5 -0.00588539
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -0.00587787
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.005875
MEN1 multiple endocrine neoplasia I -0.00583734
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 -0.00582863
IFI44 interferon-induced protein 44 -0.0058226
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00581759
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00581145
TRIB2 tribbles pseudokinase 2 -0.00580998
CCL19 chemokine (C-C motif) ligand 19 -0.00579549
LAMA4 laminin, alpha 4 -0.00578354
SFN stratifin -0.00575381
GPX3 glutathione peroxidase 3 -0.00573927
GLS glutaminase -0.00572932
MFAP4 microfibrillar-associated protein 4 -0.0057288
NBEA neurobeachin -0.00571923
SNAP25 synaptosomal-associated protein, 25kDa -0.00571461
LYZ lysozyme -0.00570614
U2AF1 U2 small nuclear RNA auxiliary factor 1 -0.00568668
BST2 bone marrow stromal cell antigen 2 -0.00564651
EFHD2 EF-hand domain family, member D2 -0.00563284
NOVA1 neuro-oncological ventral antigen 1 -0.00563148
SQLE squalene epoxidase -0.00562409
IGF1 insulin-like growth factor 1 (somatomedin C) -0.00562241
LHFPL2 lipoma HMGIC fusion partner-like 2 -0.00561911
APOA2 apolipoprotein A-II -0.00561086
TWIST1 twist family bHLH transcription factor 1 -0.00559167
AREG amphiregulin -0.00556901
PPAP2A phosphatidic acid phosphatase type 2A -0.00554777
MOXD1 monooxygenase, DBH-like 1 -0.00554076
MIR22HG MIR22 host gene -0.0055341
GKN1 gastrokine 1 -0.00551808
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.00548117
MN1 meningioma (disrupted in balanced translocation) 1 -0.00547894
PLXND1 plexin D1 -0.00547111
CADPS2 Ca++-dependent secretion activator 2 -0.00546562
IL1R1 interleukin 1 receptor, type I -0.00545354
IGFBP4 insulin-like growth factor binding protein 4 -0.00544779
COL16A1 collagen, type XVI, alpha 1 -0.00541967
COL9A3 collagen, type IX, alpha 3 -0.00541378
CPB1 carboxypeptidase B1 (tissue) -0.00539322
KLF2 Kruppel-like factor 2 -0.00535419
ARL14 ADP-ribosylation factor-like 14 -0.00534705
IFI44L interferon-induced protein 44-like -0.00530342
HAND2-AS1 HAND2 antisense RNA 1 (head to head) -0.00527076
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.00526612
PLXNA2 plexin A2 -0.00524362
TIMP1 TIMP metallopeptidase inhibitor 1 -0.00523822
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.00522208
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.00521453
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -0.00520783
RGS16 regulator of G-protein signaling 16 -0.00519446
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00518777
H1-10 H1.10 linker histone -0.00518237
CCDC88A coiled-coil domain containing 88A -0.00517323
MTMR11 myotubularin related protein 11 -0.00517197
COL10A1 collagen, type X, alpha 1 -0.00516148
NFASC neurofascin -0.00513904
ELOVL2 ELOVL fatty acid elongase 2 -0.00512705
PDE8B phosphodiesterase 8B -0.00512592
IQGAP2 IQ motif containing GTPase activating protein 2 -0.00512477
PRKCZ protein kinase C, zeta -0.00511993
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00511849
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00509121
CHMP2A charged multivesicular body protein 2A -0.00509045
SRSF7 serine/arginine-rich splicing factor 7 -0.00508864
EMILIN1 elastin microfibril interfacer 1 -0.00508025
C3 complement component 3 -0.00505604
IRAK1 interleukin-1 receptor-associated kinase 1 -0.00505263
CLDN10 claudin 10 -0.00504537
IRS1 insulin receptor substrate 1 -0.00504322
CXORF40B chromosome X open reading frame 40B -0.00504098
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.00502647
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00501509
EMP1 epithelial membrane protein 1 -0.00501278
LEF1 lymphoid enhancer-binding factor 1 -0.00500191
CHKA choline kinase alpha -0.00499848
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) -0.00499365
MPRIP myosin phosphatase Rho interacting protein -0.00499221
SIDT2 SID1 transmembrane family, member 2 -0.00497746
ISYNA1 inositol-3-phosphate synthase 1 -0.00496609
IER5 immediate early response 5 -0.0049612
EMP3 epithelial membrane protein 3 -0.00495569
OSR2 odd-skipped related transciption factor 2 -0.00493843
GLIPR1 GLI pathogenesis-related 1 -0.00493311
INSR insulin receptor -0.00492044
PTK2B protein tyrosine kinase 2 beta -0.00491605
DIO2 deiodinase, iodothyronine, type II -0.00490984
CADM1 cell adhesion molecule 1 -0.00490904
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.00490848
KCNK3 potassium channel, two pore domain subfamily K, member 3 -0.00490485
H1-2 H1.2 linker histone, cluster member -0.00489638
EGR1 early growth response 1 -0.00488869
ADGRL2 adhesion G protein-coupled receptor L2 -0.00488307
RASA4 RAS p21 protein activator 4 -0.00487701
AKAP12 A kinase (PRKA) anchor protein 12 -0.00487567
SCGN secretagogin, EF-hand calcium binding protein -0.0048685
ATP5MG ATP synthase membrane subunit g -0.00486577
MYBPC1 myosin binding protein C, slow type -0.00485358
PTN pleiotrophin -0.00485184
EREG epiregulin -0.00484884
CD320 CD320 molecule -0.00484191