F11 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description coagulation factor XI|This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2160)
External Link https://ncbi.nlm.nih.gov/gene/2160
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Genes

500 genes differentially expressed following the F11 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I 0.0177243
SIRT3 sirtuin 3 0.016418
RGCC regulator of cell cycle 0.015614
KRT5 keratin 5, type II 0.0154412
RGS4 regulator of G-protein signaling 4 0.0152734
HSPB1 heat shock 27kDa protein 1 0.0149786
S100A8 S100 calcium binding protein A8 0.0139119
CCN2 cellular communication network factor 2 0.013676
THBS2 thrombospondin 2 0.0125837
KRT7 keratin 7, type II 0.0125421
AREG amphiregulin 0.0122667
KRT17 keratin 17, type I 0.0121758
TACSTD2 tumor-associated calcium signal transducer 2 0.0121493
CRABP2 cellular retinoic acid binding protein 2 0.0118426
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.0118213
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.0117626
ADIRF adipogenesis regulatory factor 0.0116487
INHBA inhibin, beta A 0.0114433
EMP1 epithelial membrane protein 1 0.0113108
TRIM29 tripartite motif containing 29 0.0110354
TM4SF1 transmembrane 4 L six family member 1 0.0110331
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.0108889
ANXA1 annexin A1 0.0108592
MYBPC1 myosin binding protein C, slow type 0.0104071
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.0102169
BGN biglycan 0.0101937
MT1E metallothionein 1E 0.0101618
MT1G metallothionein 1G 0.0101398
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.010047
MT1F metallothionein 1F 0.00994716
S100A9 S100 calcium binding protein A9 0.00986316
POSTN periostin, osteoblast specific factor 0.00977161
HTRA1 HtrA serine peptidase 1 0.00974364
NEBL nebulette 0.00963901
MT1X metallothionein 1X 0.00960612
ZBED2 zinc finger, BED-type containing 2 0.00946906
FSCN1 fascin actin-bundling protein 1 0.00934849
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.00922004
CSTA cystatin A (stefin A) 0.0091049
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00910229
PELI1 pellino E3 ubiquitin protein ligase 1 0.00907866
PCOLCE procollagen C-endopeptidase enhancer 0.00903748
CRABP1 cellular retinoic acid binding protein 1 0.00895802
PPP1R16B protein phosphatase 1, regulatory subunit 16B 0.00895134
KRT6B keratin 6B, type II 0.0089386
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.00893024
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.00882271
DOK5 docking protein 5 0.00879366
ECM1 extracellular matrix protein 1 0.00875929
MT1H metallothionein 1H 0.00871542
SPRR3 small proline-rich protein 3 0.00854643
CA2 carbonic anhydrase II 0.00853544
TNNT1 troponin T type 1 (skeletal, slow) 0.00853355
ALCAM activated leukocyte cell adhesion molecule 0.00852979
VEGFA vascular endothelial growth factor A 0.00847157
AKAP8 A kinase (PRKA) anchor protein 8 0.00846782
PEG10 paternally expressed 10 0.00838885
GPNMB glycoprotein (transmembrane) nmb 0.00835344
SYT1 synaptotagmin I 0.0082462
KRT15 keratin 15, type I 0.0082314
KRT6A keratin 6A, type II 0.00821935
SLC38A1 solute carrier family 38, member 1 0.00816196
MT1HL1 metallothionein 1H-like 1 0.00811837
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00810875
THBS1 thrombospondin 1 0.0080838
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.00803892
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00800401
NT5E 5'-nucleotidase, ecto (CD73) 0.00798965
HSPH1 heat shock 105kDa/110kDa protein 1 0.00796298
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.00795083
CEL carboxyl ester lipase 0.00791703
DIPK1A divergent protein kinase domain 1A 0.00786353
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.00773425
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00770621
PDE4B phosphodiesterase 4B, cAMP-specific 0.00767532
FGFBP1 fibroblast growth factor binding protein 1 0.00766547
TAGLN transgelin 0.0076087
DAXX death-domain associated protein 0.00760311
HYAL1 hyaluronoglucosaminidase 1 0.00757446
ASS1 argininosuccinate synthase 1 0.00757038
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 0.00755754
SLPI secretory leukocyte peptidase inhibitor 0.00754165
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00742949
SPRR1A small proline-rich protein 1A 0.00740521
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 0.00728341
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00725539
PLK1 polo-like kinase 1 0.00723008
CLDN8 claudin 8 0.00718356
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00717958
MEF2C myocyte enhancer factor 2C 0.00714646
CNN2 calponin 2 0.00711687
CD200 CD200 molecule 0.00709906
LPPR4 lipid phosphate phosphatase-related protein type 4 0.00705664
CRYAB crystallin, alpha B 0.0070561
SEC14L1 SEC14-like 1 (S. cerevisiae) 0.00704195
FOXG1 forkhead box G1 0.00702161
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00701353
CCNA2 cyclin A2 0.00700412
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00698748
S100A2 S100 calcium binding protein A2 0.00698566
GRB7 growth factor receptor-bound protein 7 0.00697935
MYO1B myosin IB 0.00697351
GLUL glutamate-ammonia ligase 0.00694735
RND3 Rho family GTPase 3 0.00691003
SPRR1B small proline-rich protein 1B 0.00689795
EFHD1 EF-hand domain family, member D1 0.00685078
TFPI2 tissue factor pathway inhibitor 2 0.00683762
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.00676965
IL1RN interleukin 1 receptor antagonist 0.00669698
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00669195
ACAN aggrecan 0.00669105
HSPA1A heat shock 70kDa protein 1A 0.00668613
CXCL12 chemokine (C-X-C motif) ligand 12 0.0066659
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00662716
GSTP1 glutathione S-transferase pi 1 0.00660073
PLS3 plastin 3 0.00659456
TIMP3 TIMP metallopeptidase inhibitor 3 0.00658163
VTCN1 V-set domain containing T cell activation inhibitor 1 0.00656554
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.00655087
CLIC5 chloride intracellular channel 5 0.00653048
KRT19 keratin 19, type I 0.00651439
FABP4 fatty acid binding protein 4, adipocyte 0.00651044
GADD45A growth arrest and DNA-damage-inducible, alpha 0.0065
FN1 fibronectin 1 0.00649468
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00647458
CTSD cathepsin D 0.00645265
KLF7 Kruppel-like factor 7 (ubiquitous) 0.00642871
CREB3L2 cAMP responsive element binding protein 3-like 2 0.00642558
KLF6 Kruppel-like factor 6 0.00641351
LAMC2 laminin, gamma 2 0.00637842
FXYD5 FXYD domain containing ion transport regulator 5 0.00637186
GPX7 glutathione peroxidase 7 0.00635047
SLN sarcolipin 0.00634053
SDC4 syndecan 4 0.00630161
CCT8 chaperonin containing TCP1, subunit 8 (theta) 0.00628002
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.00627951
ABHD11 abhydrolase domain containing 11 0.00625295
CHMP1B charged multivesicular body protein 1B 0.00625191
DSP desmoplakin 0.00624737
CA12 carbonic anhydrase XII 0.00622811
SULF1 sulfatase 1 0.00619417
PDLIM1 PDZ and LIM domain 1 0.00616464
LIMS1 LIM and senescent cell antigen-like domains 1 0.00615465
GJA1 gap junction protein, alpha 1, 43kDa 0.0061177
BTG3 BTG family, member 3 0.00611345
RCAN1 regulator of calcineurin 1 0.00610797
ALOX15B arachidonate 15-lipoxygenase, type B 0.00609383
KRT16 keratin 16, type I 0.006062
GSTZ1 glutathione S-transferase zeta 1 0.00605448
SGCE sarcoglycan, epsilon 0.00602855
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.00602607
TPM4 tropomyosin 4 0.00600156
PCLO piccolo presynaptic cytomatrix protein 0.00600041
MPZL2 myelin protein zero-like 2 0.00597231
H1-0 H1.0 linker histone 0.00595131
MAOB monoamine oxidase B 0.00591931
CCNC cyclin C 0.00591909
MFAP3L microfibrillar-associated protein 3-like 0.00591881
CEMIP cell migration inducing protein, hyaluronan binding 0.00589598
MT1M metallothionein 1M 0.00586941
MMP7 matrix metallopeptidase 7 0.00585064
INHBB inhibin, beta B 0.00584928
CDK14 cyclin-dependent kinase 14 0.00584857
FGFR4 fibroblast growth factor receptor 4 0.00583868
PLAUR plasminogen activator, urokinase receptor 0.00583694
SYT17 synaptotagmin XVII 0.00582107
MXRA7 matrix-remodelling associated 7 0.00581039
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 0.00579557
MRPL40 mitochondrial ribosomal protein L40 0.00579246
AK5 adenylate kinase 5 0.00576622
DDN dendrin 0.00575194
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.00574547
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 0.00573646
SKAP2 src kinase associated phosphoprotein 2 0.0057164
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 0.00571089
CLDN3 claudin 3 0.00569744
NEFM neurofilament, medium polypeptide 0.00569158
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.00568568
DGKA diacylglycerol kinase, alpha 80kDa 0.00568145
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00566427
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 0.00564024
SMAGP small cell adhesion glycoprotein 0.00563223
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00562808
HACD2 3-hydroxyacyl-CoA dehydratase 2 0.00562289
SPHK1 sphingosine kinase 1 0.0056214
KRT13 keratin 13, type I 0.00560554
TSPAN7 tetraspanin 7 0.00559851
ADCY2 adenylate cyclase 2 (brain) 0.0055948
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.0055934
EDN1 endothelin 1 0.00557329
KRT18 keratin 18, type I 0.00556635
TNNC1 troponin C type 1 (slow) 0.00556558
TINAGL1 tubulointerstitial nephritis antigen-like 1 0.00555621
RFTN1 raftlin, lipid raft linker 1 0.00555374
HLA-DOB major histocompatibility complex, class II, DO beta 0.0055488
GRAMD2B GRAM domain containing 2B 0.00554237
SIRPA signal-regulatory protein alpha 0.005537
AK1 adenylate kinase 1 0.00552959
STC2 stanniocalcin 2 0.00550923
ASXL2 additional sex combs like transcriptional regulator 2 0.00550562
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.00545678
BTF3P11 basic transcription factor 3 pseudogene 11 0.0054511
SMYD2 SET and MYND domain containing 2 0.00544859
MMP19 matrix metallopeptidase 19 0.00544725
RAB13 RAB13, member RAS oncogene family 0.00542194
MMP9 matrix metallopeptidase 9 0.00539318
DLX5 distal-less homeobox 5 0.0053813
ALOX5 arachidonate 5-lipoxygenase 0.00537196
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 0.00535699
TGFA transforming growth factor, alpha 0.0053312
EPAS1 endothelial PAS domain protein 1 0.0053288
SIK1 salt-inducible kinase 1 0.00532356
ETHE1 ethylmalonic encephalopathy 1 0.00531151
USP25 ubiquitin specific peptidase 25 0.00531029
IRF6 interferon regulatory factor 6 0.0052977
CAST calpastatin 0.00528768
CNN3 calponin 3, acidic 0.00528367
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 0.0052766
FOXO1 forkhead box O1 0.00526809
TFRC transferrin receptor 0.00526552
NDE1 nudE neurodevelopment protein 1 0.00525734
ELF5 E74-like factor 5 (ets domain transcription factor) 0.00524742
TRPS1 trichorhinophalangeal syndrome I 0.00524599
GLUD2 glutamate dehydrogenase 2 0.00522799
VSNL1 visinin-like 1 0.00520594
APOLD1 apolipoprotein L domain containing 1 0.00520387
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00517901
ATF3 activating transcription factor 3 0.00517887
EPS8L2 EPS8-like 2 0.00517659
COPZ2 coatomer protein complex, subunit zeta 2 0.0051758
PRKCI protein kinase C, iota 0.00516936
TPD52L1 tumor protein D52-like 1 0.0051672
SP100 SP100 nuclear antigen 0.00515642
LDB2 LIM domain binding 2 0.00514274
THY1 Thy-1 cell surface antigen 0.00513945
MSMO1 methylsterol monooxygenase 1 0.00513877
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 0.0051357
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.00513459
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.00512946
FCRL2 Fc receptor-like 2 0.00511791
GLYAT glycine-N-acyltransferase 0.00511426
TPST2 tyrosylprotein sulfotransferase 2 0.00510425
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.00509467
TXNL1 thioredoxin-like 1 0.00509235
THBD thrombomodulin 0.00508679
PTK2B protein tyrosine kinase 2 beta 0.00507552
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00507275
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.00505778
GLO1 glyoxalase I 0.00505202
S100A14 S100 calcium binding protein A14 0.00504298

decreased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 -0.0191669
MAP7 microtubule-associated protein 7 -0.0165086
CLGN calmegin -0.0142105
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.0127341
COL4A5 collagen, type IV, alpha 5 -0.0126295
RRAGA Ras-related GTP binding A -0.0126023
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.0124656
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0120405
AGR2 anterior gradient 2 -0.0118709
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.0111373
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0104394
CLU clusterin -0.00990347
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00989391
KANK2 KN motif and ankyrin repeat domains 2 -0.0098701
FOXF1 forkhead box F1 -0.00981273
REEP1 receptor accessory protein 1 -0.00963582
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00954596
NTS neurotensin -0.00949375
BST2 bone marrow stromal cell antigen 2 -0.00935386
FGL2 fibrinogen-like 2 -0.00933833
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.00931133
CST3 cystatin C -0.00930353
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -0.00925083
TOX3 TOX high mobility group box family member 3 -0.0091513
TSPAN8 tetraspanin 8 -0.00903255
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00902856
HMGN5 high mobility group nucleosome binding domain 5 -0.00884317
PLXNC1 plexin C1 -0.00873276
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00854699
FBXO11 F-box protein 11 -0.00851468
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00846013
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -0.00834459
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00822143
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00821694
EPB41L3 erythrocyte membrane protein band 4.1-like 3 -0.00816222
FAM13A family with sequence similarity 13, member A -0.00815679
NVL nuclear VCP-like -0.0080451
CXCL11 chemokine (C-X-C motif) ligand 11 -0.00802306
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00801219
LAPTM4B lysosomal protein transmembrane 4 beta -0.00799912
KLHL23 kelch-like family member 23 -0.00790046
KCNK3 potassium channel, two pore domain subfamily K, member 3 -0.00786053
ITM2A integral membrane protein 2A -0.00783504
PLAT plasminogen activator, tissue -0.00782451
VLDLR very low density lipoprotein receptor -0.00781603
WASHC4 WASH complex subunit 4 -0.00779221
PBX1 pre-B-cell leukemia homeobox 1 -0.00778883
OLFM4 olfactomedin 4 -0.00777858
COL15A1 collagen, type XV, alpha 1 -0.00777794
CPVL carboxypeptidase, vitellogenic-like -0.00777592
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00774131
CD99 CD99 molecule -0.00764809
TKTL1 transketolase-like 1 -0.00761685
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00756859
IQGAP2 IQ motif containing GTPase activating protein 2 -0.00744943
TENT5A terminal nucleotidyltransferase 5A -0.00740009
REG3A regenerating islet-derived 3 alpha -0.00739
IFI44L interferon-induced protein 44-like -0.00738157
HOXB6 homeobox B6 -0.00736125
OSR2 odd-skipped related transciption factor 2 -0.00734831
NEFH neurofilament, heavy polypeptide -0.00734192
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.00732038
PTCH1 patched 1 -0.00730142
AMD1 adenosylmethionine decarboxylase 1 -0.00726761
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00725103
NBPF10 neuroblastoma breakpoint family, member 10 -0.00722939
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00717812
QPCT glutaminyl-peptide cyclotransferase -0.00714171
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.0071157
IRS2 insulin receptor substrate 2 -0.00709069
PRDX2 peroxiredoxin 2 -0.0070799
MLPH melanophilin -0.00704938
FXYD6 FXYD domain containing ion transport regulator 6 -0.00702191
SUCO SUN domain containing ossification factor -0.00700405
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.00696447
NELL2 NEL-like 2 (chicken) -0.00695337
GPX3 glutathione peroxidase 3 -0.0069273
GALC galactosylceramidase -0.00690174
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -0.00684755
SAMHD1 SAM domain and HD domain 1 -0.00683299
CCL8 chemokine (C-C motif) ligand 8 -0.00682891
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.00680457
COL21A1 collagen, type XXI, alpha 1 -0.00670277
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.0066968
LTBP2 latent transforming growth factor beta binding protein 2 -0.0066653
SUB1 SUB1 homolog (S. cerevisiae) -0.00664782
PRUNE2 prune homolog 2 (Drosophila) -0.00664712
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -0.00664215
TXNIP thioredoxin interacting protein -0.00663754
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -0.00663467
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00662879
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00660647
SIDT2 SID1 transmembrane family, member 2 -0.00658557
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.00654936
RERE arginine-glutamic acid dipeptide (RE) repeats -0.00654025
ANKRD10 ankyrin repeat domain 10 -0.0065302
PELI2 pellino E3 ubiquitin protein ligase family member 2 -0.00652878
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.00651179
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.0064783
ACKR3 atypical chemokine receptor 3 -0.00647664
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.00642071
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.00636728
BMI1 BMI1 proto-oncogene, polycomb ring finger -0.00634475
PTPRD protein tyrosine phosphatase, receptor type, D -0.00633359
PCSK1 proprotein convertase subtilisin/kexin type 1 -0.00633221
ETNK1 ethanolamine kinase 1 -0.00632275
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -0.00631818
PDZK1IP1 PDZK1 interacting protein 1 -0.00630248
AOX1 aldehyde oxidase 1 -0.00625435
FBXO9 F-box protein 9 -0.00624568
IFITM1 interferon induced transmembrane protein 1 -0.00623173
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -0.00621464
NOVA1 neuro-oncological ventral antigen 1 -0.00621326
NKX2-2 NK2 homeobox 2 -0.00619952
NQO2 NAD(P)H dehydrogenase, quinone 2 -0.00617766
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -0.00614778
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog -0.00614458
FAIM Fas apoptotic inhibitory molecule -0.00614236
FAM13B family with sequence similarity 13, member B -0.00614122
ZSCAN31 zinc finger and SCAN domain containing 31 -0.00610366
LAMC1 laminin, gamma 1 (formerly LAMB2) -0.00609564
COL4A6 collagen, type IV, alpha 6 -0.0060895
SMC1A structural maintenance of chromosomes 1A -0.00606999
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00606627
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00605109
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00603602
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) -0.00602092
IFI27 interferon, alpha-inducible protein 27 -0.00599832
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.00599344
SEPP1 selenoprotein P, plasma, 1 -0.00598591
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.00597214
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha -0.00594828
KLF3-AS1 KLF3 antisense RNA 1 -0.00594334
MTMR11 myotubularin related protein 11 -0.0059271
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -0.00592279
UBP1 upstream binding protein 1 (LBP-1a) -0.00591079
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 -0.00589522
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -0.00587356
IFI6 interferon, alpha-inducible protein 6 -0.00585384
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 -0.00585225
EDRF1 erythroid differentiation regulatory factor 1 -0.00583088
MOCOS molybdenum cofactor sulfurase -0.00579214
GCH1 GTP cyclohydrolase 1 -0.00577579
INTS6 integrator complex subunit 6 -0.00576615
PCNXL4 pecanex-like 4 (Drosophila) -0.00576006
CCL19 chemokine (C-C motif) ligand 19 -0.00574894
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -0.00574045
ZCCHC24 zinc finger, CCHC domain containing 24 -0.00572585
FAM46C family with sequence similarity 46, member C -0.0057246
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -0.00571802
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant -0.00571565
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) -0.00571222
PMP22 peripheral myelin protein 22 -0.00569461
C8ORF4 chromosome 8 open reading frame 4 -0.00568296
CALCA calcitonin-related polypeptide alpha -0.00566309
PLCB4 phospholipase C, beta 4 -0.005658
NDN necdin, melanoma antigen (MAGE) family member -0.00565505
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00565069
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 -0.0056432
SLIT2 slit homolog 2 (Drosophila) -0.00562854
AFF1 AF4/FMR2 family, member 1 -0.00562601
SI sucrase-isomaltase (alpha-glucosidase) -0.0056202
MMP3 matrix metallopeptidase 3 -0.00561465
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.0056059
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00558513
KLC1 kinesin light chain 1 -0.00557975
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00557131
VANGL1 VANGL planar cell polarity protein 1 -0.00554753
MSX1 msh homeobox 1 -0.00550281
USP48 ubiquitin specific peptidase 48 -0.00550113
RUFY3 RUN and FYVE domain containing 3 -0.00549285
NOTCH2NL notch 2 N-terminal like -0.00549044
MLH3 mutL homolog 3 -0.00546527
AKAP7 A kinase (PRKA) anchor protein 7 -0.0054541
LDLRAP1 low density lipoprotein receptor adaptor protein 1 -0.00543939
CASP1 caspase 1, apoptosis-related cysteine peptidase -0.00542689
MPPED2 metallophosphoesterase domain containing 2 -0.0054206
GLCE glucuronic acid epimerase -0.0054158
REG1A regenerating islet-derived 1 alpha -0.0054139
VCL vinculin -0.00540824
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -0.00540273
TGFBR3 transforming growth factor, beta receptor III -0.00539129
MAGED1 melanoma antigen family D1 -0.00539021
NINJ2 ninjurin 2 -0.00537864
NPR3 natriuretic peptide receptor 3 -0.00537562
CALCB calcitonin-related polypeptide beta -0.00537145
TRIM36 tripartite motif containing 36 -0.0053698
IPW imprinted in Prader-Willi syndrome (non-protein coding) -0.00536791
ITGA7 integrin, alpha 7 -0.00536767
CMTR1 cap methyltransferase 1 -0.00536529
RAD23B RAD23 homolog B (S. cerevisiae) -0.00535429
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic -0.00534481
GSPT2 G1 to S phase transition 2 -0.00533775
ACE2 angiotensin I converting enzyme 2 -0.00531323
RP2 retinitis pigmentosa 2 (X-linked recessive) -0.00529115
ULK2 unc-51 like autophagy activating kinase 2 -0.00528456
TRPC1 transient receptor potential cation channel, subfamily C, member 1 -0.00527885
RBPMS RNA binding protein with multiple splicing -0.00527836
TLE2 transducin-like enhancer of split 2 -0.00526436
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.00526207
GPC4 glypican 4 -0.00525742
CHN2 chimerin 2 -0.00525644
ADGRG2 adhesion G protein-coupled receptor G2 -0.00525241
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 -0.00523636
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 -0.00523321
SCG5 secretogranin V -0.005233
FOXA1 forkhead box A1 -0.00523181
KDM5A lysine (K)-specific demethylase 5A -0.00523066
ZNF302 zinc finger protein 302 -0.00522668
S100A4 S100 calcium binding protein A4 -0.00522654
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 -0.00522319
FBXL14 F-box and leucine-rich repeat protein 14 -0.00521538
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.00521509
HIPK1 homeodomain interacting protein kinase 1 -0.00521268
GAS1 growth arrest-specific 1 -0.00519283
CRY1 cryptochrome circadian clock 1 -0.00518532
SOX11 SRY (sex determining region Y)-box 11 -0.00517725
NSG1 neuron specific gene family member 1 -0.00517053
FOXF2 forkhead box F2 -0.00516781
SLC44A4 solute carrier family 44, member 4 -0.00515684
ELOVL5 ELOVL fatty acid elongase 5 -0.00515015
C2CD5 C2 calcium-dependent domain containing 5 -0.00514612
ARG1 arginase 1 -0.0051399
BBX bobby sox homolog (Drosophila) -0.00513351
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00513114
DENND5A DENN/MADD domain containing 5A -0.00510788
ISG15 ISG15 ubiquitin-like modifier -0.00509277
STXBP2 syntaxin binding protein 2 -0.00507571
ACP3 acid phosphatase 3 -0.00507351
MLEC malectin -0.00505956
PAPOLA poly(A) polymerase alpha -0.00505568
PDZRN3 PDZ domain containing ring finger 3 -0.00503866
MFAP4 microfibrillar-associated protein 4 -0.00502757
ARID4B AT rich interactive domain 4B (RBP1-like) -0.00498878
NANOG Nanog homeobox -0.00498762
MGLL monoglyceride lipase -0.00498009
SVIL supervillin -0.00497923
BCHE butyrylcholinesterase -0.00497082
TBX3 T-box 3 -0.00496126
TIGAR TP53 induced glycolysis regulatory phosphatase -0.00495609
NAV3 neuron navigator 3 -0.00495533
PNMA1 paraneoplastic Ma antigen 1 -0.00495342
BMPR1A bone morphogenetic protein receptor, type IA -0.00495301
KIF1B kinesin family member 1B -0.00494477
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.00494113
MMP1 matrix metallopeptidase 1 -0.00493829
RHOH ras homolog family member H -0.00491795
TMX1 thioredoxin-related transmembrane protein 1 -0.00491682
COL1A2 collagen, type I, alpha 2 -0.00490759
BTBD3 BTB (POZ) domain containing 3 -0.00489638