F12 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description coagulation factor XII (Hageman factor)|This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2161)
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Genes

373 genes differentially expressed following the F12 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 2.6782
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein 2.6782
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 2.6782
ANGPTL7 angiopoietin-like 7 2.6782
RHCE Rh blood group, CcEe antigens 2.6782
PCDHGB7 protocadherin gamma subfamily B, 7 2.6782
PLCZ1 phospholipase C, zeta 1 2.6782
TBC1D3L TBC1 domain family, member 3L 2.6782
BDKRB2 bradykinin receptor B2 2.6782
TTR transthyretin 2.6782
MYL10 myosin, light chain 10, regulatory 2.6782
ADORA2B adenosine A2b receptor 2.6782
TXLNB taxilin beta 2.6782
GJA4 gap junction protein, alpha 4, 37kDa 2.6782
CREG2 cellular repressor of E1A-stimulated genes 2 2.6782
GP2 glycoprotein 2 (zymogen granule membrane) 2.6782
NLRP1 NLR family, pyrin domain containing 1 2.6782
DRC1 dynein regulatory complex subunit 1 2.6782
VPREB3 pre-B lymphocyte 3 2.6782
ADCY4 adenylate cyclase 4 2.6782
VXN vexin 2.6782
ARRDC2 arrestin domain containing 2 2.6782
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 2.67726
CORO6 coronin 6 2.67726
MTNR1B melatonin receptor 1B 2.67726
HLX H2.0-like homeobox 2.67726
EGFLAM EGF-like, fibronectin type III and laminin G domains 2.67726
IL2RG interleukin 2 receptor, gamma 2.67726
CEP126 centrosomal protein 126kDa 2.67726
CRYGB crystallin, gamma B 2.67726
NR1H4 nuclear receptor subfamily 1, group H, member 4 2.67726
PLVAP plasmalemma vesicle associated protein 2.67726
HNF4A hepatocyte nuclear factor 4, alpha 2.67726
NRN1 neuritin 1 2.67726
OR5H2 olfactory receptor, family 5, subfamily H, member 2 2.67726
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 2.67726
CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) 2.67726
SLC35D3 solute carrier family 35, member D3 2.67726
OR2A5 olfactory receptor, family 2, subfamily A, member 5 2.67726
BPIFA2 BPI fold containing family A, member 2 2.67726
FRMD7 FERM domain containing 7 2.67726
PCDHA7 protocadherin alpha 7 2.67726
PRDM12 PR domain containing 12 2.67726
HBD hemoglobin, delta 2.67726
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 2.67726
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 2.67726
LRRC10B leucine rich repeat containing 10B 2.67726
RSPO1 R-spondin 1 2.67726
ZNF556 zinc finger protein 556 2.67726
TRPV6 transient receptor potential cation channel, subfamily V, member 6 2.67726
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 2.67726
PTGER4 prostaglandin E receptor 4 (subtype EP4) 2.67726
C16ORF86 chromosome 16 open reading frame 86 2.67726
APLN apelin 2.67726
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 2.67726
CHRND cholinergic receptor, nicotinic, delta (muscle) 2.67726
RXFP1 relaxin/insulin-like family peptide receptor 1 2.67726
CD1D CD1d molecule 2.67726
TTLL2 tubulin tyrosine ligase-like family member 2 2.67726
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 2.67726
BTK Bruton agammaglobulinemia tyrosine kinase 2.67726
OR6A2 olfactory receptor, family 6, subfamily A, member 2 2.67726
GLRA3 glycine receptor, alpha 3 2.67726
NOD2 nucleotide-binding oligomerization domain containing 2 2.67726
SLC4A9 solute carrier family 4, sodium bicarbonate cotransporter, member 9 2.67726
CIROZ ciliated left-right organizer protein containing ZP-N domains 2.67726
RTL9 retrotransposon Gag like 9 2.67726
ANKRD40CL ANKRD40 C-terminal like 2.67726
PLAAT4 phospholipase A and acyltransferase 4 2.67726
TMEM271 transmembrane protein 271 2.67726
SMIM38 small integral membrane protein 38 2.67726
SMIM41 small integral membrane protein 41 2.67726
GGTA1 glycoprotein alpha-galactosyltransferase 1 (inactive) 2.67726
NECTIN4 nectin cell adhesion molecule 4 2.67726
ERVW-1 endogenous retrovirus group W, member 1 2.67726
ALDOB aldolase B, fructose-bisphosphate 2.67726
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 2.67726
CCDC163 CCDC163 homolog 2.67726
RTL5 retrotransposon Gag like 5 2.67726
DNAAF19 dynein axonemal assembly factor 19 2.67726
PNMA6F PNMA family member 6F 2.67726
SMIM32 small integral membrane protein 32 2.67726
CIMAP1B ciliary microtubule associated protein 1B 2.67726
SMIM45 small integral membrane protein 45 2.67726
H4C12 H4 clustered histone 12 2.67726
H4C14 H4 clustered histone 14 2.67726
KLF18 KLF transcription factor 18 2.67726
PJVK pejvakin 2.67726
DUSP29 dual specificity phosphatase 29 2.67726
SPATA31G1 SPATA31 subfamily G member 1 2.67726
ZNF521 zinc finger protein 521 2.67726
AANAT aralkylamine N-acetyltransferase 2.67726
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 2.67726
GJD2 gap junction protein, delta 2, 36kDa 2.67726
KCNT1 potassium channel, sodium activated subfamily T, member 1 2.67726
GLP2R glucagon-like peptide 2 receptor 2.67726
MYH15 myosin, heavy chain 15 2.67726
MYH13 myosin, heavy chain 13, skeletal muscle 2.67726
MSX1 msh homeobox 1 2.67726
ULBP1 UL16 binding protein 1 2.67726
SP140 SP140 nuclear body protein 2.67726
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 2.67726
AKR1D1 aldo-keto reductase family 1, member D1 2.67726
C7 complement component 7 2.67726
MPPED1 metallophosphoesterase domain containing 1 2.67726
LOC124906892 uncharacterized LOC124906892 2.67726
DNAAF1 dynein, axonemal, assembly factor 1 2.67726
STMN4 stathmin-like 4 2.67726
SPRR2D small proline-rich protein 2D 2.67726
SLC2A7 solute carrier family 2 (facilitated glucose transporter), member 7 2.67726
ADRB3 adrenoceptor beta 3 2.67726
BDKRB1 bradykinin receptor B1 2.67726
LY6K lymphocyte antigen 6 complex, locus K 2.67726
CLEC6A C-type lectin domain family 6, member A 2.67726
PILRA paired immunoglobin-like type 2 receptor alpha 2.67726
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 2.67726
AMBP alpha-1-microglobulin/bikunin precursor 2.67726
MYO1G myosin IG 2.67726
A3GALT2 alpha 1,3-galactosyltransferase 2 2.67726
EMP1 epithelial membrane protein 1 2.67726
C2CD4B C2 calcium-dependent domain containing 4B 2.67726
LMOD3 leiomodin 3 (fetal) 2.67726
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 2.67726
MUC13 mucin 13, cell surface associated 2.67726
CCL15 chemokine (C-C motif) ligand 15 2.67726
MAPK8 mitogen-activated protein kinase 8 2.67726
CHI3L2 chitinase 3-like 2 2.67726
MLIP muscular LMNA-interacting protein 2.67726
SAMD8 sterile alpha motif domain containing 8 2.67726
MSR1 macrophage scavenger receptor 1 2.67726
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 2.67726
PLET1 placenta expressed transcript 1 2.67726
NOG noggin 2.67726
CT55 cancer/testis antigen 55 2.67726
EDN1 endothelin 1 2.67726
LRTM2 leucine-rich repeats and transmembrane domains 2 2.67726
ZNF541 zinc finger protein 541 2.67726
EFCAB3 EF-hand calcium binding domain 3 2.67726
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) 2.67726
THTPA thiamine triphosphatase 2.67726
CXCR2 chemokine (C-X-C motif) receptor 2 2.67726
ANKRD61 ankyrin repeat domain 61 2.67726
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 2.67726
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 2.67726
LY96 lymphocyte antigen 96 2.67726
ITGB7 integrin, beta 7 2.67726
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 2.67726
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 2.67726
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 2.67726
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 2.67726
PCDHAC2 protocadherin alpha subfamily C, 2 2.67726
CNR2 cannabinoid receptor 2 (macrophage) 2.67726
ZNF835 zinc finger protein 835 2.67726
ZNF831 zinc finger protein 831 2.67726
STRC stereocilin 2.67726
GJC2 gap junction protein, gamma 2, 47kDa 2.67726
CFB complement factor B 2.67726
LOXHD1 lipoxygenase homology domains 1 2.67726
LRRC25 leucine rich repeat containing 25 2.67726
TG thyroglobulin 2.67726
ANKRD53 ankyrin repeat domain 53 2.67726
TPPP3 tubulin polymerization-promoting protein family member 3 2.67726
SIGLEC15 sialic acid binding Ig-like lectin 15 2.67726
CDH17 cadherin 17, LI cadherin (liver-intestine) 2.67726
TMEM31 transmembrane protein 31 2.67726
FANCL Fanconi anemia, complementation group L 2.67726
SOS2 son of sevenless homolog 2 (Drosophila) 2.67726
PLCD4 phospholipase C, delta 4 2.67726
CD28 CD28 molecule 2.67726
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 2.67726
ART1 ADP-ribosyltransferase 1 2.67726
SLFN12L schlafen family member 12-like 2.67726
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A 2.67726
CD38 CD38 molecule 2.67726
POPDC2 popeye domain containing 2 2.67726
CHRDL2 chordin-like 2 2.67726
TNMD tenomodulin 2.67726
GPRC5D G protein-coupled receptor, class C, group 5, member D 2.67726
RNF223 ring finger protein 223 2.67726
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 2.67726
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 2.67726
ANGPTL3 angiopoietin-like 3 2.67726
RERGL RERG/RAS-like 2.67726
ANGPTL6 angiopoietin-like 6 2.67726
NATD1 N-acetyltransferase domain containing 1 2.67726
CIB4 calcium and integrin binding family member 4 2.67726
GREM1 gremlin 1, DAN family BMP antagonist 2.67726
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 2.67726
C4BPB complement component 4 binding protein, beta 2.67726
PMCH pro-melanin-concentrating hormone 2.67726
NPAS4 neuronal PAS domain protein 4 2.67726
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 2.67726
ASGR2 asialoglycoprotein receptor 2 2.67726
OR4D9 olfactory receptor, family 4, subfamily D, member 9 2.67726
C2ORF78 chromosome 2 open reading frame 78 2.67726
HCK HCK proto-oncogene, Src family tyrosine kinase 2.67726
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 2.67726
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 2.67726
PRSS54 protease, serine, 54 2.67726
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 2.67726
ACAN aggrecan 2.67726
MT1A metallothionein 1A 2.67726
SLC7A4 solute carrier family 7, member 4 2.67726
STAP1 signal transducing adaptor family member 1 2.67726
EPO erythropoietin 2.67726
SUN3 Sad1 and UNC84 domain containing 3 2.67726
KIAA1755 KIAA1755 2.67726
TRIM29 tripartite motif containing 29 2.67726
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa 2.66731
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 2.63727
EFNA5 ephrin-A5 2.61949
ERC2 ELKS/RAB6-interacting/CAST family member 2 2.60034
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 2.57393
TAGLN2 transgelin 2 2.51005
PSME4 proteasome (prosome, macropain) activator subunit 4 2.50875
CCDC28B coiled-coil domain containing 28B 2.50615
KLK8 kallikrein-related peptidase 8 2.48577
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 2.48294
ASPG asparaginase 2.48294
RBPMS RNA binding protein with multiple splicing 2.476
RND3 Rho family GTPase 3 2.46068
TBC1D7-LOC100130357 TBC1D7-LOC100130357 readthrough 2.37767
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 2.34147
DEGS2 delta(4)-desaturase, sphingolipid 2 2.33347
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 2.33347
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 2.32664
AHRR aryl-hydrocarbon receptor repressor 2.32664
FNIP1 folliculin interacting protein 1 2.31691
PAN3 PAN3 poly(A) specific ribonuclease subunit 2.30921
TTC14 tetratricopeptide repeat domain 14 2.24791
ZNF143 zinc finger protein 143 2.23035
RIN3 Ras and Rab interactor 3 2.22631
ZRANB3 zinc finger, RAN-binding domain containing 3 2.22631
PPAN peter pan homolog (Drosophila) 2.21967
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 2.21967
PTER phosphotriesterase related 2.21876
LMNB2 lamin B2 2.20483
CDC37L1 cell division cycle 37-like 1 2.20451
TMEM74B transmembrane protein 74B 2.1764
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.16614
UBAP2 ubiquitin associated protein 2 2.14993
LRRC42 leucine rich repeat containing 42 2.12112
DLL3 delta-like 3 (Drosophila) 2.07216
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A 2.05926
DARS1 aspartyl-tRNA synthetase 1 2.03597
FRMD4A FERM domain containing 4A 2.03229
FRA10AC1 fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1 2.02736
CAPN5 calpain 5 2.00855
CHD9 chromodomain helicase DNA binding protein 9 2.00845
ACSS2 acyl-CoA synthetase short-chain family member 2 2.00431
SCGB3A2 secretoglobin, family 3A, member 2 2.00431

decreased expression

Symbol Name Standardized Value
DUSP28 dual specificity phosphatase 28 -2.6782
COL6A3 collagen, type VI, alpha 3 -2.6782
CRK v-crk avian sarcoma virus CT10 oncogene homolog -2.6782
COL8A1 collagen, type VIII, alpha 1 -2.6782
SHISA4 shisa family member 4 -2.6782
AURKC aurora kinase C -2.6782
ELFN1 extracellular leucine-rich repeat and fibronectin type III domain containing 1 -2.6782
CA9 carbonic anhydrase IX -2.67726
TRPC5OS TRPC5 opposite strand -2.67726
CSTL1 cystatin-like 1 -2.67726
SULT6B1 sulfotransferase family, cytosolic, 6B, member 1 -2.67726
VCX variable charge, X-linked -2.67726
TMC3 transmembrane channel-like 3 -2.67726
ZNF804B zinc finger protein 804B -2.67726
NPB neuropeptide B -2.67726
ANXA6 annexin A6 -2.67726
TGM7 transglutaminase 7 -2.67726
LIX1L Lix1 homolog (chicken) like -2.67726
MORC3 MORC family CW-type zinc finger 3 -2.67726
LMO1 LIM domain only 1 (rhombotin 1) -2.67726
PI15 peptidase inhibitor 15 -2.67726
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) -2.67726
TASOR2 transcription activation suppressor family member 2 -2.67726
TMEM126B transmembrane protein 126B -2.67726
KLB klotho beta -2.67726
TMPRSS9 transmembrane protease, serine 9 -2.67726
ZSCAN31 zinc finger and SCAN domain containing 31 -2.67726
DDTL D-dopachrome tautomerase-like -2.67726
PP2D1 protein phosphatase 2C-like domain containing 1 -2.67726
PGLYRP1 peptidoglycan recognition protein 1 -2.67726
CNTFR ciliary neurotrophic factor receptor -2.67726
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa -2.67726
ZBTB16 zinc finger and BTB domain containing 16 -2.67726
POMC proopiomelanocortin -2.67726
MOSPD3 motile sperm domain containing 3 -2.67726
SIX1 SIX homeobox 1 -2.67726
PTMA prothymosin, alpha -2.67726
LURAP1L leucine rich adaptor protein 1-like -2.67726
SPMIP8 sperm microtubule inner protein 8 -2.67726
SPTBN4 spectrin, beta, non-erythrocytic 4 -2.67726
PLAC8L1 PLAC8-like 1 -2.67726
TNNI3K TNNI3 interacting kinase -2.67726
PCYOX1L prenylcysteine oxidase 1 like -2.67726
ARHGAP40 Rho GTPase activating protein 40 -2.67726
PPP1R27 protein phosphatase 1, regulatory subunit 27 -2.67726
ERVV-2 endogenous retrovirus group V, member 2 -2.67726
RFX3 regulatory factor X, 3 (influences HLA class II expression) -2.67726
ZNF75D zinc finger protein 75D -2.67726
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like -2.67726
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2 -2.67726
FNDC8 fibronectin type III domain containing 8 -2.67726
HHAT hedgehog acyltransferase -2.67726
CHMP6 charged multivesicular body protein 6 -2.67726
KCTD19 potassium channel tetramerization domain containing 19 -2.67726
LINC02560 long intergenic non-protein coding RNA 2560 -2.67726
C19ORF18 chromosome 19 open reading frame 18 -2.67726
TTC29 tetratricopeptide repeat domain 29 -2.67726
LCN2 lipocalin 2 -2.67726
MRPL15 mitochondrial ribosomal protein L15 -2.65198
CEMIP cell migration inducing protein, hyaluronan binding -2.65162
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -2.60034
SFSWAP splicing factor, suppressor of white-apricot family -2.476
DCAF15 DDB1 and CUL4 associated factor 15 -2.42282
NAF1 nuclear assembly factor 1 ribonucleoprotein -2.41978
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -2.40364
ERO1B endoplasmic reticulum oxidoreductase 1 beta -2.35725
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 -2.35333
POU3F4 POU class 3 homeobox 4 -2.35333
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) -2.33347
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 -2.33267
BUD31 BUD31 homolog (S. cerevisiae) -2.33185
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) -2.30921
PBDC1 polysaccharide biosynthesis domain containing 1 -2.28613
TGFB3 transforming growth factor, beta 3 -2.28437
MEGF10-DT MEGF10 divergent transcript -2.28437
C6ORF163 chromosome 6 open reading frame 163 -2.28245
RNASE4 ribonuclease, RNase A family, 4 -2.28245
RIF1 replication timing regulatory factor 1 -2.28245
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -2.28245
SMTNL2 smoothelin-like 2 -2.28245
MAP3K12 mitogen-activated protein kinase kinase kinase 12 -2.25658
TNPO2 transportin 2 -2.24422
ZNF343 zinc finger protein 343 -2.24422
CLDN1 claudin 1 -2.24422
WDR72 WD repeat domain 72 -2.24422
CAPN6 calpain 6 -2.24422
TRIM21 tripartite motif containing 21 -2.23682
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 -2.23092
NIT1 nitrilase 1 -2.21967
ZNF572 zinc finger protein 572 -2.21641
OMA1 OMA1 zinc metallopeptidase -2.2133
AFF2 AF4/FMR2 family, member 2 -2.1931
SVBP small vasohibin binding protein -2.19018
DOK4 docking protein 4 -2.18186
SPA17 sperm autoantigenic protein 17 -2.16771
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.16614
ZNF81 zinc finger protein 81 -2.15282
PLEKHO1 pleckstrin homology domain containing, family O member 1 -2.15282
TMTC1 transmembrane and tetratricopeptide repeat containing 1 -2.14993
POLG polymerase (DNA directed), gamma -2.14797
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34 -2.14328
ZFP91 ZFP91 zinc finger protein -2.12263
LUZP1 leucine zipper protein 1 -2.11026
CADPS2 Ca++-dependent secretion activator 2 -2.11026
GGT1 gamma-glutamyltransferase 1 -2.09892
AGFG1 ArfGAP with FG repeats 1 -2.09892
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) -2.09818
MED8 mediator complex subunit 8 -2.08406
DMXL1 Dmx-like 1 -2.07379
LY6E lymphocyte antigen 6 complex, locus E -2.07355
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -2.07216
GADD45G growth arrest and DNA-damage-inducible, gamma -2.05456
OTOG otogelin -2.05456
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1) -2.05203
LYSMD4 LysM, putative peptidoglycan-binding, domain containing 4 -2.05154
CCDC141 coiled-coil domain containing 141 -2.05129
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) -2.04687
KDM4D lysine (K)-specific demethylase 4D -2.03355
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric -2.01831
C20ORF203 chromosome 20 open reading frame 203 -2.00855
EXOSC2 exosome component 2 -2.00845
ANKLE2 ankyrin repeat and LEM domain containing 2 -2.00647