| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | Fas (TNFRSF6)-associated via death domain|The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8772) |
| External Link | https://ncbi.nlm.nih.gov/gene/8772 |
| Similar Terms | |
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497 genes differentially expressed following the FADD gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT1X | metallothionein 1X | 0.0147628 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0139767 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0137802 |
| KRT7 | keratin 7, type II | 0.0129596 |
| MT1E | metallothionein 1E | 0.0128585 |
| MT1G | metallothionein 1G | 0.0127178 |
| MT1H | metallothionein 1H | 0.0117342 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.0112015 |
| KRT14 | keratin 14, type I | 0.0103281 |
| MT1F | metallothionein 1F | 0.010193 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00975075 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00971853 |
| MT1HL1 | metallothionein 1H-like 1 | 0.0097113 |
| CA2 | carbonic anhydrase II | 0.0096874 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00948538 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00937828 |
| S100A7 | S100 calcium binding protein A7 | 0.00934481 |
| HTRA1 | HtrA serine peptidase 1 | 0.00906854 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00902159 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00902149 |
| S100P | S100 calcium binding protein P | 0.00901974 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00893722 |
| IFI44L | interferon-induced protein 44-like | 0.00887609 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.00864487 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00844585 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00832564 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.0082203 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.0082017 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00804377 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00803281 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.00798233 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.0079653 |
| REEP5 | receptor accessory protein 5 | 0.00795835 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 0.00792653 |
| BAX | BCL2-associated X protein | 0.00777162 |
| TNS3 | tensin 3 | 0.0076598 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00743189 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00742993 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00724618 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00723308 |
| MT2A | metallothionein 2A | 0.00721502 |
| THBS2 | thrombospondin 2 | 0.0071992 |
| LBH | limb bud and heart development | 0.00703901 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00701211 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00699778 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.00698533 |
| LUM | lumican | 0.00689009 |
| KRT23 | keratin 23, type I | 0.00686304 |
| MX1 | MX dynamin-like GTPase 1 | 0.00678412 |
| KRT17 | keratin 17, type I | 0.00671732 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00668497 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00666401 |
| SDC1 | syndecan 1 | 0.00663449 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.0066159 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00658029 |
| EREG | epiregulin | 0.00656572 |
| ANXA1 | annexin A1 | 0.00650401 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00644575 |
| RPS27L | ribosomal protein S27-like | 0.00639312 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00635079 |
| RND3 | Rho family GTPase 3 | 0.00635024 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00627801 |
| TMEM59 | transmembrane protein 59 | 0.00622072 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00621511 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00618985 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.00618362 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00616641 |
| HIST1H2BK | histone cluster 1, H2bk | 0.00615014 |
| RBM47 | RNA binding motif protein 47 | 0.00614941 |
| MPO | myeloperoxidase | 0.00611681 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00611358 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00610389 |
| TSPAN7 | tetraspanin 7 | 0.00607318 |
| CTSB | cathepsin B | 0.0060609 |
| TRIM22 | tripartite motif containing 22 | 0.00605763 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | 0.00603834 |
| COL11A1 | collagen, type XI, alpha 1 | 0.00599041 |
| MYBPC1 | myosin binding protein C, slow type | 0.00598272 |
| JAG1 | jagged 1 | 0.0059615 |
| MT1M | metallothionein 1M | 0.00594911 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00594098 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.0059134 |
| SDC4 | syndecan 4 | 0.00588454 |
| SPRR1B | small proline-rich protein 1B | 0.00585612 |
| MAGEA3 | melanoma antigen family A3 | 0.00585458 |
| INHBB | inhibin, beta B | 0.00584686 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00582822 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00581272 |
| JUNB | jun B proto-oncogene | 0.00579544 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00579309 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.00575587 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00574211 |
| ITGAV | integrin, alpha V | 0.0057282 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00572569 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 0.00572532 |
| PLAU | plasminogen activator, urokinase | 0.00572141 |
| SP110 | SP110 nuclear body protein | 0.00571554 |
| CTSK | cathepsin K | 0.00568547 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.00567923 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.00565974 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00565179 |
| KRT20 | keratin 20, type I | 0.00563796 |
| KRT6A | keratin 6A, type II | 0.00562998 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0056026 |
| HOMER1 | homer scaffolding protein 1 | 0.0055955 |
| ASS1 | argininosuccinate synthase 1 | 0.00557157 |
| DIO2 | deiodinase, iodothyronine, type II | 0.00554468 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 0.00550761 |
| GPX2 | glutathione peroxidase 2 | 0.00550315 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00548806 |
| RAB13 | RAB13, member RAS oncogene family | 0.00548413 |
| KRT16 | keratin 16, type I | 0.00545931 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.00544097 |
| KRT5 | keratin 5, type II | 0.00543699 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.00539208 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.00538368 |
| CA12 | carbonic anhydrase XII | 0.00537967 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00536502 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00535728 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0053571 |
| C1S | complement component 1, s subcomponent | 0.00534685 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00532778 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00531961 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00529984 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.00527329 |
| OPN3 | opsin 3 | 0.00526435 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00525103 |
| LRRC17 | leucine rich repeat containing 17 | 0.0052498 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.00520208 |
| GOLGA8A | golgin A8 family, member A | 0.00520162 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.00519074 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00517326 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00516984 |
| MYO1C | myosin IC | 0.00516846 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00514257 |
| BGN | biglycan | 0.0051176 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00511685 |
| BCL2A1 | BCL2-related protein A1 | 0.00510655 |
| DUSP6 | dual specificity phosphatase 6 | 0.00510507 |
| IFI35 | interferon-induced protein 35 | 0.00510056 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | 0.00509425 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.00507275 |
| INAVA | innate immunity activator | 0.00506457 |
| SQOR | sulfide quinone oxidoreductase | 0.00506392 |
| GPI | glucose-6-phosphate isomerase | 0.00505834 |
| GPR137B | G protein-coupled receptor 137B | 0.00504786 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00503901 |
| RIN2 | Ras and Rab interactor 2 | 0.00503007 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00502859 |
| PRAME | preferentially expressed antigen in melanoma | 0.00502687 |
| PON2 | paraoxonase 2 | 0.00501786 |
| CCNG2 | cyclin G2 | 0.00500486 |
| CYBB | cytochrome b-245, beta polypeptide | 0.00495592 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00493797 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 | 0.00492352 |
| ETHE1 | ethylmalonic encephalopathy 1 | 0.0049217 |
| AREG | amphiregulin | 0.00490912 |
| CYTL1 | cytokine-like 1 | 0.00488933 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00488484 |
| MAPK13 | mitogen-activated protein kinase 13 | 0.00487147 |
| KLK10 | kallikrein-related peptidase 10 | 0.004847 |
| TPBG | trophoblast glycoprotein | 0.00483736 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.00482731 |
| COX5B | cytochrome c oxidase subunit Vb | 0.00481737 |
| MYOF | myoferlin | 0.00481588 |
| ABAT | 4-aminobutyrate aminotransferase | 0.00480455 |
| LOXL2 | lysyl oxidase-like 2 | 0.00478549 |
| CLDN7 | claudin 7 | 0.00476964 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00474901 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00474848 |
| LXN | latexin | 0.00474824 |
| IRF1 | interferon regulatory factor 1 | 0.00474622 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00473685 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00472975 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.00472838 |
| PHF11 | PHD finger protein 11 | 0.00472189 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.0047116 |
| TMEM140 | transmembrane protein 140 | 0.00470258 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 0.00469334 |
| RNASET2 | ribonuclease T2 | 0.00468673 |
| TPD52 | tumor protein D52 | 0.00468453 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.00468263 |
| ISCU | iron-sulfur cluster assembly enzyme | 0.00462727 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 0.00458407 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | 0.00457212 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00455866 |
| NDUFB2 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa | 0.00455509 |
| JUP | junction plakoglobin | 0.00455421 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 | 0.00454414 |
| ARL4A | ADP-ribosylation factor-like 4A | 0.00454322 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.00453913 |
| MALL | mal, T-cell differentiation protein-like | 0.00453481 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00452942 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | 0.00450629 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | 0.00449393 |
| RABAC1 | Rab acceptor 1 (prenylated) | 0.00448703 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 0.00447444 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00447232 |
| EXT1 | exostosin glycosyltransferase 1 | 0.00446854 |
| PGAP3 | post-GPI attachment to proteins 3 | 0.00446713 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00446504 |
| CSTB | cystatin B (stefin B) | 0.00445268 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 0.0044503 |
| NUTF2 | nuclear transport factor 2 | 0.00443686 |
| EZR | ezrin | 0.00443611 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00443463 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00442797 |
| S100A6 | S100 calcium binding protein A6 | 0.00442268 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00441452 |
| CLIC5 | chloride intracellular channel 5 | 0.00441112 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | 0.00440651 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.00439358 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0043897 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.00438792 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.00438695 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00438068 |
| MFSD1 | major facilitator superfamily domain containing 1 | 0.00437829 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00437768 |
| MZB1 | marginal zone B and B1 cell-specific protein | 0.00437281 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.00436984 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.00436374 |
| SPP1 | secreted phosphoprotein 1 | 0.00436159 |
| FNDC3B | fibronectin type III domain containing 3B | 0.00435254 |
| MX2 | MX dynamin-like GTPase 2 | 0.00435227 |
| APOL1 | apolipoprotein L, 1 | 0.00435145 |
| ZNF395 | zinc finger protein 395 | 0.00434958 |
| FRZB | frizzled-related protein | 0.00434716 |
| PSAP | prosaposin | 0.0043445 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00433345 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00432653 |
| CA4 | carbonic anhydrase IV | 0.00432474 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 0.00432464 |
| SCEL | sciellin | 0.0043205 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.00431679 |
| IFI44 | interferon-induced protein 44 | 0.00429759 |
| TMEM100 | transmembrane protein 100 | 0.00429156 |
| IRF7 | interferon regulatory factor 7 | 0.00428347 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.0042785 |
| TAPBP | TAP binding protein (tapasin) | 0.00427459 |
| POSTN | periostin, osteoblast specific factor | 0.00427221 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | 0.00427084 |
| KLHL24 | kelch-like family member 24 | 0.00426688 |
| STX8 | syntaxin 8 | 0.00424559 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.00423162 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 0.00422024 |
| SQSTM1 | sequestosome 1 | 0.00421637 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits | 0.004207 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | -0.0107899 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00894973 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00853216 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00852279 |
| DACH1 | dachshund family transcription factor 1 | -0.00822759 |
| MEIS2 | Meis homeobox 2 | -0.00781558 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00778823 |
| REEP1 | receptor accessory protein 1 | -0.00773048 |
| APOA2 | apolipoprotein A-II | -0.00734384 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00713739 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00702049 |
| APOB | apolipoprotein B | -0.00674037 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.00672739 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.00663566 |
| GPC3 | glypican 3 | -0.00650684 |
| APOA1 | apolipoprotein A-I | -0.00647077 |
| ESR1 | estrogen receptor 1 | -0.00639923 |
| SCG5 | secretogranin V | -0.00638974 |
| MPZL2 | myelin protein zero-like 2 | -0.00637164 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00620262 |
| CEP57 | centrosomal protein 57kDa | -0.00620207 |
| APOD | apolipoprotein D | -0.00620019 |
| HOXB2 | homeobox B2 | -0.00612156 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00611789 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -0.00606653 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00606609 |
| REG3A | regenerating islet-derived 3 alpha | -0.00604559 |
| RETREG1 | reticulophagy regulator 1 | -0.0060076 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.00597666 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0059398 |
| BCL2 | B-cell CLL/lymphoma 2 | -0.00592265 |
| AHSG | alpha-2-HS-glycoprotein | -0.00585915 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00584163 |
| ASRGL1 | asparaginase like 1 | -0.0058356 |
| APOC3 | apolipoprotein C-III | -0.00567958 |
| EXPH5 | exophilin 5 | -0.00565478 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.00565454 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00562998 |
| REG1A | regenerating islet-derived 1 alpha | -0.00562557 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00561993 |
| SDC2 | syndecan 2 | -0.00558725 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -0.00557069 |
| TMSB15A | thymosin beta 15a | -0.00556591 |
| TFF1 | trefoil factor 1 | -0.00553345 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00552271 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00551359 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00551345 |
| ZW10 | zw10 kinetochore protein | -0.0054787 |
| GLUL | glutamate-ammonia ligase | -0.00547372 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00547256 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00542925 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.00539912 |
| HAUS4 | HAUS augmin-like complex, subunit 4 | -0.00539726 |
| PGC | progastricsin (pepsinogen C) | -0.00533362 |
| INSM1 | insulinoma-associated 1 | -0.00533072 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00530152 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.0052702 |
| GATA3 | GATA binding protein 3 | -0.00525839 |
| PDZK1 | PDZ domain containing 1 | -0.00524766 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) | -0.00521043 |
| FOXM1 | forkhead box M1 | -0.00520574 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00517674 |
| CD99 | CD99 molecule | -0.00511939 |
| C4BPB | complement component 4 binding protein, beta | -0.00511392 |
| FNBP1 | formin binding protein 1 | -0.00510139 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00507635 |
| THYN1 | thymocyte nuclear protein 1 | -0.00506945 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | -0.00503827 |
| HIP1 | huntingtin interacting protein 1 | -0.00501561 |
| RPIA | ribose 5-phosphate isomerase A | -0.00498615 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.00496895 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00496768 |
| SOCS2 | suppressor of cytokine signaling 2 | -0.00494719 |
| PRKCB | protein kinase C, beta | -0.00492277 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00491839 |
| PITX1 | paired-like homeodomain 1 | -0.0049083 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00490385 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00487593 |
| CD2 | CD2 molecule | -0.0048759 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | -0.0048661 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | -0.00485028 |
| CFI | complement factor I | -0.00484961 |
| PLLP | plasmolipin | -0.00483977 |
| ARCN1 | archain 1 | -0.00483596 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00482983 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.00482667 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00481012 |
| DUSP1 | dual specificity phosphatase 1 | -0.00478836 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00478521 |
| CD44 | CD44 molecule (Indian blood group) | -0.00477041 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00476613 |
| NELL2 | NEL-like 2 (chicken) | -0.00474459 |
| ARG2 | arginase 2 | -0.0047435 |
| MEIS1 | Meis homeobox 1 | -0.00472526 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00472335 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.00471642 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.00471514 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00470644 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00468859 |
| IL6ST | interleukin 6 signal transducer | -0.00467424 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | -0.00467214 |
| FAM107A | family with sequence similarity 107, member A | -0.00466806 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | -0.00466711 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.00466697 |
| SYBU | syntabulin (syntaxin-interacting) | -0.00465872 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain | -0.0046508 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.00463927 |
| PER3 | period circadian clock 3 | -0.0046384 |
| INSIG1 | insulin induced gene 1 | -0.00463577 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.00463451 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | -0.00463393 |
| MANSC1 | MANSC domain containing 1 | -0.00461475 |
| NREP | neuronal regeneration related protein | -0.00461284 |
| ABHD6 | abhydrolase domain containing 6 | -0.00460987 |
| PAGE4 | P antigen family, member 4 (prostate associated) | -0.00460982 |
| VANGL1 | VANGL planar cell polarity protein 1 | -0.00460968 |
| TTR | transthyretin | -0.00459654 |
| ALB | albumin | -0.0045776 |
| CD302 | CD302 molecule | -0.00455854 |
| FST | follistatin | -0.00455666 |
| DUSP2 | dual specificity phosphatase 2 | -0.00455026 |
| NNAT | neuronatin | -0.00453837 |
| CDCA3 | cell division cycle associated 3 | -0.00453705 |
| MECOM | MDS1 and EVI1 complex locus | -0.00453549 |
| FKBP5 | FK506 binding protein 5 | -0.00451796 |
| CELP | carboxyl ester lipase pseudogene | -0.00451468 |
| FSD1 | fibronectin type III and SPRY domain containing 1 | -0.00450896 |
| WBP5 | WW domain binding protein 5 | -0.00450374 |
| C11ORF71 | chromosome 11 open reading frame 71 | -0.00448514 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00448491 |
| GSTA4 | glutathione S-transferase alpha 4 | -0.00447909 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | -0.00447559 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.00445305 |
| PEG3 | paternally expressed 3 | -0.00444601 |
| MMP1 | matrix metallopeptidase 1 | -0.00444347 |
| PIR | pirin (iron-binding nuclear protein) | -0.00440402 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | -0.00439593 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00439404 |
| HP | haptoglobin | -0.00439218 |
| IRX5 | iroquois homeobox 5 | -0.00438007 |
| SOX17 | SRY (sex determining region Y)-box 17 | -0.00437898 |
| DBP | D site of albumin promoter (albumin D-box) binding protein | -0.0043729 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -0.00436212 |
| DCK | deoxycytidine kinase | -0.00435957 |
| CD1D | CD1d molecule | -0.00435147 |
| IFRD2 | interferon-related developmental regulator 2 | -0.00433695 |
| NAGA | N-acetylgalactosaminidase, alpha- | -0.00431796 |
| RESF1 | retroelement silencing factor 1 | -0.00431548 |
| RDX | radixin | -0.00430872 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00429783 |
| ASGR2 | asialoglycoprotein receptor 2 | -0.00427333 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | -0.00426895 |
| CD320 | CD320 molecule | -0.00425377 |
| TMEM126B | transmembrane protein 126B | -0.00424519 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00423884 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.00423725 |
| RNF130 | ring finger protein 130 | -0.00422244 |
| CCKBR | cholecystokinin B receptor | -0.00421744 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.00421711 |
| ITM2A | integral membrane protein 2A | -0.00421424 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00420849 |
| RGCC | regulator of cell cycle | -0.00420325 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -0.00419814 |
| DEK | DEK proto-oncogene | -0.00419657 |
| NUP160 | nucleoporin 160kDa | -0.0041955 |
| RAD51AP1 | RAD51 associated protein 1 | -0.00419081 |
| LAPTM5 | lysosomal protein transmembrane 5 | -0.00418413 |
| UBE4A | ubiquitination factor E4A | -0.00416713 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | -0.00416283 |
| ITGB7 | integrin, beta 7 | -0.00415089 |
| CSK | c-src tyrosine kinase | -0.0041127 |
| PKP2 | plakophilin 2 | -0.00410759 |
| SCARB1 | scavenger receptor class B, member 1 | -0.00410112 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.00410088 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | -0.00409972 |
| HPN | hepsin | -0.00409293 |
| TSPAN4 | tetraspanin 4 | -0.0040866 |
| DNM1L | dynamin 1-like | -0.00408586 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00407741 |
| TULP3 | tubby like protein 3 | -0.00407557 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | -0.00406677 |
| GTPBP8 | GTP-binding protein 8 (putative) | -0.0040658 |
| AGR2 | anterior gradient 2 | -0.00405303 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.0040242 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00402025 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00402004 |
| STC1 | stanniocalcin 1 | -0.0040144 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.00400283 |
| CSNK1E | casein kinase 1, epsilon | -0.00400129 |
| SPRY2 | sprouty homolog 2 (Drosophila) | -0.00399602 |
| PCP4 | Purkinje cell protein 4 | -0.00399483 |
| IPO5 | importin 5 | -0.00399214 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0039791 |
| LIG1 | ligase I, DNA, ATP-dependent | -0.00397698 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | -0.00394814 |
| TLN1 | talin 1 | -0.00394367 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.00394235 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.00393063 |
| NOVA1 | neuro-oncological ventral antigen 1 | -0.0039303 |
| MELK | maternal embryonic leucine zipper kinase | -0.00392583 |
| TRAF5 | TNF receptor-associated factor 5 | -0.00391985 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.00390754 |
| VTN | vitronectin | -0.00390681 |
| SNRPA | small nuclear ribonucleoprotein polypeptide A | -0.00390272 |
| POLA2 | polymerase (DNA directed), alpha 2, accessory subunit | -0.0039024 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.00389298 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I | -0.00388987 |
| OLFM1 | olfactomedin 1 | -0.00388912 |
| FEN1 | flap structure-specific endonuclease 1 | -0.00388815 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00387039 |
| NDUFAF3 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 | -0.00386764 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.00386663 |
| FAM198B | family with sequence similarity 198, member B | -0.00384854 |
| ISOC1 | isochorismatase domain containing 1 | -0.00384685 |
| H2AX | H2A.X variant histone | -0.00384406 |
| MTMR2 | myotubularin related protein 2 | -0.00383828 |
| MDFIC | MyoD family inhibitor domain containing | -0.00383574 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | -0.00383473 |
| HRAS | Harvey rat sarcoma viral oncogene homolog | -0.00383359 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 | -0.0038334 |
| ARHGAP45 | Rho GTPase activating protein 45 | -0.00382678 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.00381611 |
| CCDC86 | coiled-coil domain containing 86 | -0.00381517 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | -0.0038123 |
| GATA6 | GATA binding protein 6 | -0.00381166 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | -0.00379597 |
| MCF2L | MCF.2 cell line derived transforming sequence-like | -0.00379402 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.00378673 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00378473 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00378005 |
| MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase | -0.00377359 |
| TRIP13 | thyroid hormone receptor interactor 13 | -0.00377074 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00376664 |
| LOX | lysyl oxidase | -0.00375608 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -0.0037554 |
| LRP2 | low density lipoprotein receptor-related protein 2 | -0.00375496 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00374598 |
| NID1 | nidogen 1 | -0.00374481 |
| EMP1 | epithelial membrane protein 1 | -0.00374424 |
| HYOU1 | hypoxia up-regulated 1 | -0.00373964 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.00373541 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | -0.00373527 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | -0.00373489 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.00373144 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.00373087 |
| ZNF22 | zinc finger protein 22 | -0.00372809 |
| DLAT | dihydrolipoamide S-acetyltransferase | -0.00372371 |
| KLHDC3 | kelch domain containing 3 | -0.0037108 |
| C4BPA | complement component 4 binding protein, alpha | -0.00370632 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00369104 |
