FANCL Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description Fanconi anemia, complementation group L|The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 55120)
External Link http://www.ncbi.nlm.nih.gov/gene/55120
Similar Terms
Downloads & Tools

Genes

44 interacting proteins for FANCL from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACVR1 activin A receptor, type I
APITD1 apoptosis-inducing, TAF9-like domain 1
ATR ATR serine/threonine kinase
ATRIP ATR interacting protein
BARD1 BRCA1 associated RING domain 1
BMPR1B bone morphogenetic protein receptor, type IB
BRCA1 breast cancer 1, early onset
C17ORF70 chromosome 17 open reading frame 70
C19ORF40 chromosome 19 open reading frame 40
C1ORF86 chromosome 1 open reading frame 86
CHEK1 checkpoint kinase 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
FANCA Fanconi anemia, complementation group A
FANCB Fanconi anemia, complementation group B
FANCC Fanconi anemia, complementation group C
FANCD2 Fanconi anemia, complementation group D2
FANCF Fanconi anemia, complementation group F
FANCG Fanconi anemia, complementation group G
FANCI Fanconi anemia, complementation group I
FANCM Fanconi anemia, complementation group M
GGN gametogenetin
HES1 hes family bHLH transcription factor 1
HUS1 HUS1 checkpoint homolog (S. pombe)
NRF1 nuclear respiratory factor 1
PCNA proliferating cell nuclear antigen
RAD1 RAD1 checkpoint DNA exonuclease
RAD17 RAD17 homolog (S. pombe)
RAD9A RAD9 homolog A (S. pombe)
RFC2 replication factor C (activator 1) 2, 40kDa
RFC3 replication factor C (activator 1) 3, 38kDa
RFC4 replication factor C (activator 1) 4, 37kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
RPA1 replication protein A1, 70kDa
RPA2 replication protein A2, 32kDa
RPS27A ribosomal protein S27a
STRA13 stimulated by retinoic acid 13
TGFBR1 transforming growth factor, beta receptor 1
TOPBP1 topoisomerase (DNA) II binding protein 1
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBD ubiquitin D
UBE2T ubiquitin-conjugating enzyme E2T
UBE2W ubiquitin-conjugating enzyme E2W (putative)