FASTKD2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description FAST kinase domains 2|This gene encodes a protein that is localized in the mitochondrial inner compartment and that may play a role in mitochondrial apoptosis. Nonsense mutations have been reported to result in cytochrome c oxidase deficiency. [provided by RefSeq, Oct 2008] (NCBI Entrez Gene Database, 22868)
External Link https://ncbi.nlm.nih.gov/gene/22868
Similar Terms
Downloads & Tools

Genes

499 genes differentially expressed following the FASTKD2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 0.0239775
KRT14 keratin 14, type I 0.0171965
S100A9 S100 calcium binding protein A9 0.0165132
CSTA cystatin A (stefin A) 0.0134294
OXA1L oxidase (cytochrome c) assembly 1-like 0.0127411
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.0126794
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.0119373
KANK1 KN motif and ankyrin repeat domains 1 0.0112569
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.0103436
KRT16 keratin 16, type I 0.0103417
S100A12 S100 calcium binding protein A12 0.00998276
HSPA1A heat shock 70kDa protein 1A 0.00983741
FABP4 fatty acid binding protein 4, adipocyte 0.00959751
VTCN1 V-set domain containing T cell activation inhibitor 1 0.0093256
KRT5 keratin 5, type II 0.00928278
SLC38A1 solute carrier family 38, member 1 0.00907517
ACSL1 acyl-CoA synthetase long-chain family member 1 0.00896122
NNMT nicotinamide N-methyltransferase 0.00895793
SCGB2A2 secretoglobin, family 2A, member 2 0.00894928
KRT6A keratin 6A, type II 0.00888831
STC2 stanniocalcin 2 0.00876681
S100A11 S100 calcium binding protein A11 0.00871492
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00862039
SCGB1D2 secretoglobin, family 1D, member 2 0.00849652
LTF lactotransferrin 0.00838087
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00828348
CCN2 cellular communication network factor 2 0.00795456
MPO myeloperoxidase 0.00790511
THBS2 thrombospondin 2 0.00785658
EGR1 early growth response 1 0.00783247
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00776225
RAI14 retinoic acid induced 14 0.00772852
ELANE elastase, neutrophil expressed 0.00772835
FADS3 fatty acid desaturase 3 0.00770647
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00769849
LTBP2 latent transforming growth factor beta binding protein 2 0.00769802
SRGN serglycin 0.00765222
KRT6B keratin 6B, type II 0.00758355
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00751024
IFITM2 interferon induced transmembrane protein 2 0.00743327
CEL carboxyl ester lipase 0.00730618
SMYD2 SET and MYND domain containing 2 0.00729522
PCNA proliferating cell nuclear antigen 0.00726974
INHBA inhibin, beta A 0.00724174
PCCB propionyl CoA carboxylase, beta polypeptide 0.00718898
TRIM22 tripartite motif containing 22 0.00716275
RFTN1 raftlin, lipid raft linker 1 0.00709361
SPRR1B small proline-rich protein 1B 0.00707054
VEGFC vascular endothelial growth factor C 0.00702678
KRT15 keratin 15, type I 0.006999
OXTR oxytocin receptor 0.00697522
APOD apolipoprotein D 0.0068567
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00684152
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.00681122
RPL10 ribosomal protein L10 0.00679428
CYTL1 cytokine-like 1 0.00676608
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.0066897
PRTN3 proteinase 3 0.00666368
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00665155
SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.00664023
ALB albumin 0.00663626
SMAD3 SMAD family member 3 0.00661694
TRIB3 tribbles pseudokinase 3 0.00660599
LRRC17 leucine rich repeat containing 17 0.00659105
TMEM131L transmembrane 131 like 0.00659028
SIX1 SIX homeobox 1 0.00658422
PAX5 paired box 5 0.00656112
NSDHL NAD(P) dependent steroid dehydrogenase-like 0.00655541
CRYAB crystallin, alpha B 0.00642229
RAB29 RAB29, member RAS oncogene family 0.00641945
AZU1 azurocidin 1 0.00639336
IFITM3 interferon induced transmembrane protein 3 0.00634416
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 0.00634309
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00634205
KRT7 keratin 7, type II 0.0062892
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 0.00627521
ANXA3 annexin A3 0.00616989
UPK1B uroplakin 1B 0.00615812
CYB5A cytochrome b5 type A (microsomal) 0.00613853
TRIM29 tripartite motif containing 29 0.00613383
PERP PERP, TP53 apoptosis effector 0.00612476
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.006112
KRT23 keratin 23, type I 0.00608354
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.00607886
ZMYM2 zinc finger, MYM-type 2 0.0060141
IGLL1 immunoglobulin lambda-like polypeptide 1 0.00598077
MYO6 myosin VI 0.00595258
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.00593417
KRT17 keratin 17, type I 0.00591352
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00591039
RRAGD Ras-related GTP binding D 0.0058633
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 0.0058138
CXCL8 chemokine (C-X-C motif) ligand 8 0.00581123
GATA3 GATA binding protein 3 0.00578525
PILRB paired immunoglobin-like type 2 receptor beta 0.00576757
APMAP adipocyte plasma membrane associated protein 0.00571721
TPD52L2 tumor protein D52-like 2 0.00571677
HEBP2 heme binding protein 2 0.00570529
BCL2A1 BCL2-related protein A1 0.00568643
TXNDC9 thioredoxin domain containing 9 0.00566289
LMCD1 LIM and cysteine-rich domains 1 0.00566263
CLIC3 chloride intracellular channel 3 0.00565666
HMOX1 heme oxygenase 1 0.00565331
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00562584
AQP9 aquaporin 9 0.00562156
SOX10 SRY (sex determining region Y)-box 10 0.00558697
S100A2 S100 calcium binding protein A2 0.00557986
CD79B CD79b molecule, immunoglobulin-associated beta 0.00556135
ABLIM1 actin binding LIM protein 1 0.00555117
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 0.00554275
ZMAT3 zinc finger, matrin-type 3 0.00554023
TPSAB1 tryptase alpha/beta 1 0.00553318
MT1X metallothionein 1X 0.00550879
COMMD3 COMM domain containing 3 0.00550834
ELF5 E74-like factor 5 (ets domain transcription factor) 0.00550362
AKR1C3 aldo-keto reductase family 1, member C3 0.00549821
ALCAM activated leukocyte cell adhesion molecule 0.00547035
PKP4 plakophilin 4 0.00546591
DUSP2 dual specificity phosphatase 2 0.0054656
FGFR1 fibroblast growth factor receptor 1 0.0054558
ENG endoglin 0.00545201
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.0054425
NEU1 sialidase 1 (lysosomal sialidase) 0.00543607
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.0054309
BDH2 3-hydroxybutyrate dehydrogenase, type 2 0.00540781
PREB prolactin regulatory element binding 0.00540627
CFI complement factor I 0.00539776
EYA2 EYA transcriptional coactivator and phosphatase 2 0.0053666
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.0053614
PCBP4 poly(rC) binding protein 4 0.0053606
KLK5 kallikrein-related peptidase 5 0.00535837
JUP junction plakoglobin 0.00535527
PLIN1 perilipin 1 0.00532431
ANXA1 annexin A1 0.00531856
RAD51C RAD51 paralog C 0.00530143
SMAD7 SMAD family member 7 0.0052939
HSPA4L heat shock 70kDa protein 4-like 0.00528429
CYB5R2 cytochrome b5 reductase 2 0.0052822
MFGE8 milk fat globule-EGF factor 8 protein 0.00527602
FOXC1 forkhead box C1 0.00526407
MGAM maltase-glucoamylase 0.00525871
RHOBTB1 Rho-related BTB domain containing 1 0.00525618
DAD1 defender against cell death 1 0.00525534
CRABP2 cellular retinoic acid binding protein 2 0.00524033
NOX4 NADPH oxidase 4 0.00523511
GSTP1 glutathione S-transferase pi 1 0.00522062
TNF tumor necrosis factor 0.00520708
LY6D lymphocyte antigen 6 complex, locus D 0.0051939
SPRR2B small proline-rich protein 2B 0.00518869
MYB v-myb avian myeloblastosis viral oncogene homolog 0.00516125
UCKL1 uridine-cytidine kinase 1-like 1 0.00516123
GOLGA8A golgin A8 family, member A 0.00516122
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.00514881
FXYD5 FXYD domain containing ion transport regulator 5 0.00514551
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.00512097
GSAP gamma-secretase activating protein 0.00511966
CFB complement factor B 0.00511355
HP haptoglobin 0.0051094
MB myoglobin 0.0050935
SOX17 SRY (sex determining region Y)-box 17 0.00505051
DCN decorin 0.00504422
NIT2 nitrilase family, member 2 0.00504277
TRH thyrotropin-releasing hormone 0.00503387
POU4F1 POU class 4 homeobox 1 0.00501711
EIF3F eukaryotic translation initiation factor 3, subunit F 0.00499133
ACAA1 acetyl-CoA acyltransferase 1 0.0049904
PXDN peroxidasin 0.00498964
NAGK N-acetylglucosamine kinase 0.00498847
CIAO3 cytosolic iron-sulfur assembly component 3 0.00498376
CYB5R1 cytochrome b5 reductase 1 0.0049826
CXORF40B chromosome X open reading frame 40B 0.00498091
WDR41 WD repeat domain 41 0.0049784
GBAP1 glucosidase, beta, acid pseudogene 1 0.00496805
TRIM16 tripartite motif containing 16 0.00496521
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.00495918
LINC00623 long intergenic non-protein coding RNA 623 0.00495475
SPRR1A small proline-rich protein 1A 0.00495282
RETSAT retinol saturase (all-trans-retinol 13,14-reductase) 0.0049334
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.00493205
MECOM MDS1 and EVI1 complex locus 0.00491421
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 0.00490409
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.0049021
ITSN2 intersectin 2 0.00489376
FGB fibrinogen beta chain 0.00489241
MRPS12 mitochondrial ribosomal protein S12 0.00487949
ROPN1B rhophilin associated tail protein 1B 0.00487558
SPPL2B signal peptide peptidase like 2B 0.00486781
EGFL7 EGF-like-domain, multiple 7 0.00485608
YPEL5 yippee-like 5 (Drosophila) 0.00484273
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00484205
RBKS ribokinase 0.00483691
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.0048304
HIST1H2BK histone cluster 1, H2bk 0.00482079
SETD5 SET domain containing 5 0.00481757
VPREB3 pre-B lymphocyte 3 0.00481039
G0S2 G0/G1 switch 2 0.00479841
CCDC92 coiled-coil domain containing 92 0.00478269
GPI glucose-6-phosphate isomerase 0.0047717
RGS13 regulator of G-protein signaling 13 0.0047653
IRF7 interferon regulatory factor 7 0.00473044
CERS2 ceramide synthase 2 0.0047303
DHRS7 dehydrogenase/reductase (SDR family) member 7 0.00470847
RNH1 ribonuclease/angiogenin inhibitor 1 0.00470842
TMEM132A transmembrane protein 132A 0.00470342
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.00470332
STK38 serine/threonine kinase 38 0.00469794
IDI1 isopentenyl-diphosphate delta isomerase 1 0.00469748
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 0.00469662
DRAM1 DNA-damage regulated autophagy modulator 1 0.00469175
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 0.00469062
CST7 cystatin F (leukocystatin) 0.00468387
DDIT3 DNA-damage-inducible transcript 3 0.00468323
FAM50A family with sequence similarity 50, member A 0.00467087
GYPC glycophorin C (Gerbich blood group) 0.00466441
IQCG IQ motif containing G 0.00465757
KRT81 keratin 81, type II 0.0046536
ZDHHC13 zinc finger, DHHC-type containing 13 0.0046531
CSF3R colony stimulating factor 3 receptor (granulocyte) 0.0046461
RGS19 regulator of G-protein signaling 19 0.0046413
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene 0.00464061
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.00463526
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 0.00462082
SFRP4 secreted frizzled-related protein 4 0.00460478
MCOLN1 mucolipin 1 0.00460437
CLU clusterin 0.00459027
PKP1 plakophilin 1 0.0045831
INPP1 inositol polyphosphate-1-phosphatase 0.00457982
STK32B serine/threonine kinase 32B 0.00457802
DSP desmoplakin 0.00457178
EREG epiregulin 0.00456957
MAP2K2 mitogen-activated protein kinase kinase 2 0.00455992
SH3BP4 SH3-domain binding protein 4 0.00454766
GATA6 GATA binding protein 6 0.00454651
AKAP12 A kinase (PRKA) anchor protein 12 0.00454205
ATP7B ATPase, Cu++ transporting, beta polypeptide 0.00453648
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.00453142
MFAP5 microfibrillar associated protein 5 0.00451234
CXORF40A chromosome X open reading frame 40A 0.00450922
IGHMBP2 immunoglobulin mu binding protein 2 0.00450902
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.00450816
MSRA methionine sulfoxide reductase A 0.00450799
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00450217
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.00450076
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 0.00449131
SQLE squalene epoxidase 0.00448886
SEC13 SEC13 homolog (S. cerevisiae) 0.00447958
PARP2 poly (ADP-ribose) polymerase 2 0.0044784
CRCT1 cysteine-rich C-terminal 1 0.00444793
MMP11 matrix metallopeptidase 11 0.00443998

decreased expression

Symbol Name Standardized Value
CPE carboxypeptidase E -0.0185962
FCGBP Fc fragment of IgG binding protein -0.014996
SEPP1 selenoprotein P, plasma, 1 -0.0141852
PEG3 paternally expressed 3 -0.0134319
CHKB choline kinase beta -0.0134121
TSPAN8 tetraspanin 8 -0.0124952
DLK1 delta-like 1 homolog (Drosophila) -0.0124296
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0123863
CPVL carboxypeptidase, vitellogenic-like -0.0117297
RTN2 reticulon 2 -0.0113896
OLFM1 olfactomedin 1 -0.0113009
BEX1 brain expressed, X-linked 1 -0.0110398
CHGB chromogranin B -0.0108368
MEN1 multiple endocrine neoplasia I -0.0107532
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.0106157
ASS1 argininosuccinate synthase 1 -0.0103542
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.0100099
PCP4 Purkinje cell protein 4 -0.00993329
NPTX2 neuronal pentraxin II -0.00971797
FOXF1 forkhead box F1 -0.00970741
A2M alpha-2-macroglobulin -0.00943667
PCSK1 proprotein convertase subtilisin/kexin type 1 -0.00939387
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.00936037
PRUNE2 prune homolog 2 (Drosophila) -0.00933475
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.0092616
DMD dystrophin -0.00920087
CLCA1 chloride channel accessory 1 -0.00914379
NDN necdin, melanoma antigen (MAGE) family member -0.00906783
MAOA monoamine oxidase A -0.00903686
CHN2 chimerin 2 -0.00903316
AGR2 anterior gradient 2 -0.0087195
FRZB frizzled-related protein -0.00871141
COL15A1 collagen, type XV, alpha 1 -0.00856882
HNMT histamine N-methyltransferase -0.00851525
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.00848645
WFDC1 WAP four-disulfide core domain 1 -0.00848319
SDC2 syndecan 2 -0.00838698
RGS5 regulator of G-protein signaling 5 -0.00833862
RAP2A RAP2A, member of RAS oncogene family -0.00829971
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.00822716
PRKCB protein kinase C, beta -0.00815425
SCG5 secretogranin V -0.00813661
SNAP25 synaptosomal-associated protein, 25kDa -0.00809501
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00808532
MMD monocyte to macrophage differentiation-associated -0.00805696
PRDX2 peroxiredoxin 2 -0.00801742
DMBT1 deleted in malignant brain tumors 1 -0.00799371
CA2 carbonic anhydrase II -0.00797152
NELL2 NEL-like 2 (chicken) -0.00791402
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00789688
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.00788319
MYBPC1 myosin binding protein C, slow type -0.00787654
RTN1 reticulon 1 -0.00787057
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.00784186
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00779556
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00779146
TNNT1 troponin T type 1 (skeletal, slow) -0.00777794
GSTM3 glutathione S-transferase mu 3 (brain) -0.00767403
CXCL3 chemokine (C-X-C motif) ligand 3 -0.00767255
CADM1 cell adhesion molecule 1 -0.00765992
ZG16 zymogen granule protein 16 -0.00760241
INSM1 insulinoma-associated 1 -0.00757026
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00748814
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00741427
CGA glycoprotein hormones, alpha polypeptide -0.00736202
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00735911
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00734501
NID1 nidogen 1 -0.00732823
LEFTY1 left-right determination factor 1 -0.00730021
MMP12 matrix metallopeptidase 12 -0.0072982
NANOG Nanog homeobox -0.00723206
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.00718403
GPC3 glypican 3 -0.00715947
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.00714961
TSPAN6 tetraspanin 6 -0.00711833
IGSF6 immunoglobulin superfamily, member 6 -0.00706878
METTL7A methyltransferase like 7A -0.00699811
MARCKS myristoylated alanine-rich protein kinase C substrate -0.00697945
DHRS11 dehydrogenase/reductase (SDR family) member 11 -0.00697773
ETFB electron-transfer-flavoprotein, beta polypeptide -0.00696199
COL6A3 collagen, type VI, alpha 3 -0.00692285
REEP1 receptor accessory protein 1 -0.00691786
ADGRG2 adhesion G protein-coupled receptor G2 -0.00691542
CDCA4 cell division cycle associated 4 -0.00687305
TFPI2 tissue factor pathway inhibitor 2 -0.00685065
IGFBP5 insulin-like growth factor binding protein 5 -0.00684579
SMC1A structural maintenance of chromosomes 1A -0.00683701
PBX3 pre-B-cell leukemia homeobox 3 -0.00681509
DPYSL3 dihydropyrimidinase-like 3 -0.00678657
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00672854
SEZ6L2 seizure related 6 homolog (mouse)-like 2 -0.00669971
FGFR3 fibroblast growth factor receptor 3 -0.00667875
SERINC5 serine incorporator 5 -0.00664467
COLEC12 collectin sub-family member 12 -0.00662373
TFF1 trefoil factor 1 -0.00660729
TOX3 TOX high mobility group box family member 3 -0.00660449
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -0.00657463
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) -0.00654243
QKI QKI, KH domain containing, RNA binding -0.00653402
TMEM176B transmembrane protein 176B -0.00652745
MEP1A meprin A, alpha (PABA peptide hydrolase) -0.00649853
DPYD dihydropyrimidine dehydrogenase -0.00649701
NKX3-1 NK3 homeobox 1 -0.00649093
CCNB1 cyclin B1 -0.00648945
TNC tenascin C -0.00644996
RAB25 RAB25, member RAS oncogene family -0.00640221
GPA33 glycoprotein A33 (transmembrane) -0.00638653
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 -0.00638322
SOWAHC sosondowah ankyrin repeat domain family member C -0.00637759
NLRP2 NLR family, pyrin domain containing 2 -0.00637299
ACAT2 acetyl-CoA acetyltransferase 2 -0.00634461
HEPH hephaestin -0.00633307
CGRRF1 cell growth regulator with ring finger domain 1 -0.0063201
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -0.00631592
PNMA1 paraneoplastic Ma antigen 1 -0.00631158
PJA2 praja ring finger 2, E3 ubiquitin protein ligase -0.00629223
FZD5 frizzled class receptor 5 -0.00629198
COL6A2 collagen, type VI, alpha 2 -0.00628379
FGL2 fibrinogen-like 2 -0.00628172
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 -0.00626416
CPM carboxypeptidase M -0.00626375
EDNRA endothelin receptor type A -0.00625571
EIF5A eukaryotic translation initiation factor 5A -0.00625416
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00622921
CORO1C coronin, actin binding protein, 1C -0.0062065
NDFIP1 Nedd4 family interacting protein 1 -0.00615406
NEFH neurofilament, heavy polypeptide -0.00615034
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B -0.00614435
SPEN spen family transcriptional repressor -0.00614273
NLGN4X neuroligin 4, X-linked -0.00614169
ADAMDEC1 ADAM-like, decysin 1 -0.00613813
SNAI2 snail family zinc finger 2 -0.00611983
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00610579
ADORA2B adenosine A2b receptor -0.0060926
FXYD6 FXYD domain containing ion transport regulator 6 -0.00607848
GJA1 gap junction protein, alpha 1, 43kDa -0.00607751
SPARCL1 SPARC-like 1 (hevin) -0.00607225
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00606878
BMP2 bone morphogenetic protein 2 -0.00606736
ASPH aspartate beta-hydroxylase -0.00605678
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.00604538
TCEAL2 transcription elongation factor A (SII)-like 2 -0.00604493
GSTT1 glutathione S-transferase theta 1 -0.00604445
CXADR coxsackie virus and adenovirus receptor -0.00600503
SEPTIN10 septin 10 -0.00599783
TMEM176A transmembrane protein 176A -0.00599162
VDAC1 voltage-dependent anion channel 1 -0.00598101
FAXDC2 fatty acid hydroxylase domain containing 2 -0.00597547
MGLL monoglyceride lipase -0.00595794
AMD1 adenosylmethionine decarboxylase 1 -0.00595007
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -0.00594931
PARM1 prostate androgen-regulated mucin-like protein 1 -0.00594681
THY1 Thy-1 cell surface antigen -0.00594025
PGAM1 phosphoglycerate mutase 1 (brain) -0.00593584
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 -0.00593237
FST follistatin -0.00590677
ADAM28 ADAM metallopeptidase domain 28 -0.00590541
PDE9A phosphodiesterase 9A -0.00589947
FABP1 fatty acid binding protein 1, liver -0.00589538
CALD1 caldesmon 1 -0.00588805
TMEM38B transmembrane protein 38B -0.00588566
KLF10 Kruppel-like factor 10 -0.00586322
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00585273
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 -0.00582234
PITX1 paired-like homeodomain 1 -0.00579839
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00579504
TXNIP thioredoxin interacting protein -0.00578398
GCG glucagon -0.00578338
DHFR dihydrofolate reductase -0.00576488
GUCY1B3 guanylate cyclase 1, soluble, beta 3 -0.0057633
TCF7 transcription factor 7 (T-cell specific, HMG-box) -0.00573774
ARHGAP6 Rho GTPase activating protein 6 -0.00572208
LARS1 leucyl-tRNA synthetase 1 -0.00570177
CCL19 chemokine (C-C motif) ligand 19 -0.00568843
DLD dihydrolipoamide dehydrogenase -0.0056859
MATN2 matrilin 2 -0.00565383
HMMR hyaluronan-mediated motility receptor (RHAMM) -0.00565249
ACOX2 acyl-CoA oxidase 2, branched chain -0.00564687
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00563912
TNS3 tensin 3 -0.00560766
TFDP1 transcription factor Dp-1 -0.0055874
AIF1 allograft inflammatory factor 1 -0.00558359
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.005569
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00556497
FNBP1 formin binding protein 1 -0.00555566
CA11 carbonic anhydrase XI -0.00554206
KRT20 keratin 20, type I -0.00553557
CASP1 caspase 1, apoptosis-related cysteine peptidase -0.00552101
LITAF lipopolysaccharide-induced TNF factor -0.00550056
SI sucrase-isomaltase (alpha-glucosidase) -0.00549949
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 -0.00549373
CD1E CD1e molecule -0.00546846
TDP2 tyrosyl-DNA phosphodiesterase 2 -0.0054607
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -0.00545873
EPB41L3 erythrocyte membrane protein band 4.1-like 3 -0.00545793
CREBL2 cAMP responsive element binding protein-like 2 -0.00545286
ANGPT1 angiopoietin 1 -0.0054457
AOC1 amine oxidase, copper containing 1 -0.00544008
TSC22D1 TSC22 domain family, member 1 -0.00543996
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -0.00543418
PSD3 pleckstrin and Sec7 domain containing 3 -0.00542607
CNTNAP2 contactin associated protein-like 2 -0.00535534
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.00535409
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -0.00535164
CNPY3 canopy FGF signaling regulator 3 -0.00533616
CLEC7A C-type lectin domain family 7, member A -0.00532723
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00532175
SUZ12 SUZ12 polycomb repressive complex 2 subunit -0.00530469
CDK1 cyclin-dependent kinase 1 -0.00528371
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A -0.00526264
TMC5 transmembrane channel-like 5 -0.00524883
RNASE6 ribonuclease, RNase A family, k6 -0.00524843
AXL AXL receptor tyrosine kinase -0.00522406
PPAP2A phosphatidic acid phosphatase type 2A -0.00521983
CD3D CD3d molecule, delta (CD3-TCR complex) -0.00521967
CHGA chromogranin A -0.00521232
RBM47 RNA binding motif protein 47 -0.00521075
ITM2C integral membrane protein 2C -0.00520067
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.00519741
BRCA1 breast cancer 1, early onset -0.00519624
IPO5 importin 5 -0.00517912
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.0051789
COL1A2 collagen, type I, alpha 2 -0.00517384
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.00516191
COL6A1 collagen, type VI, alpha 1 -0.00516043
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.00516006
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.00513185
TADA2A transcriptional adaptor 2A -0.005131
FOXN3 forkhead box N3 -0.00513071
NUSAP1 nucleolar and spindle associated protein 1 -0.00511779
LIN28A lin-28 homolog A (C. elegans) -0.00511442
TAOK3 TAO kinase 3 -0.00510636
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00510337
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.0050998
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.00509688
NQO2 NAD(P)H dehydrogenase, quinone 2 -0.00509639
MYO1D myosin ID -0.00507761
PID1 phosphotyrosine interaction domain containing 1 -0.00506763
GNA14 guanine nucleotide binding protein (G protein), alpha 14 -0.00505429
MXI1 MAX interactor 1, dimerization protein -0.00505421
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 -0.00504751
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) -0.00504225
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.00504071
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) -0.00503717
NFE2L3 nuclear factor, erythroid 2-like 3 -0.00502052
SST somatostatin -0.00501812
BIRC3 baculoviral IAP repeat containing 3 -0.00501704
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.00501131
IRS2 insulin receptor substrate 2 -0.00499807
DYNLT3 dynein, light chain, Tctex-type 3 -0.00499437