FBL Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description fibrillarin|This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2091)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_FBL
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Genes

262 co-expressed genes for FBL from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AHCY adenosylhomocysteinase
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
ANAPC5 anaphase promoting complex subunit 5
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
ATXN10 ataxin 10
AURKB aurora kinase B
BANF1 barrier to autointegration factor 1
BTF3 basic transcription factor 3
BUB3 BUB3 mitotic checkpoint protein
C14ORF166 chromosome 14 open reading frame 166
C1QBP complement component 1, q subcomponent binding protein
CBX3 chromobox homolog 3
CCDC59 coiled-coil domain containing 59
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CDC123 cell division cycle 123
CLNS1A chloride channel, nucleotide-sensitive, 1A
CNOT7 CCR4-NOT transcription complex, subunit 7
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COX7C cytochrome c oxidase subunit VIIc
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa
CS citrate synthase
CSNK2B casein kinase 2, beta polypeptide
CYC1 cytochrome c-1
CYCS cytochrome c, somatic
DAP3 death associated protein 3
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
DEK DEK proto-oncogene
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DKC1 dyskeratosis congenita 1, dyskerin
DOCK3 dedicator of cytokinesis 3
DRG1 developmentally regulated GTP binding protein 1
EEF1B2 eukaryotic translation elongation factor 1 beta 2
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EEF1G eukaryotic translation elongation factor 1 gamma
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF3C eukaryotic translation initiation factor 3, subunit C
EIF3D eukaryotic translation initiation factor 3, subunit D
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF3G eukaryotic translation initiation factor 3, subunit G
EIF3H eukaryotic translation initiation factor 3, subunit H
EIF3I eukaryotic translation initiation factor 3, subunit I
EIF3K eukaryotic translation initiation factor 3, subunit K
EIF3L eukaryotic translation initiation factor 3, subunit L
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4B eukaryotic translation initiation factor 4B
EIF4H eukaryotic translation initiation factor 4H
EXOSC8 exosome component 8
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
FBL fibrillarin
FIBP fibroblast growth factor (acidic) intracellular binding protein
FUS FUS RNA binding protein
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GPI glucose-6-phosphate isomerase
GTF3A general transcription factor IIIA
H2AFZ H2A histone family, member Z
HCCS holocytochrome c synthase
HDAC1 histone deacetylase 1
HDGF hepatoma-derived growth factor
HINT1 histidine triad nucleotide binding protein 1
HMGN1 high mobility group nucleosome binding domain 1
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPF heterogeneous nuclear ribonucleoprotein F
HNRNPR heterogeneous nuclear ribonucleoprotein R
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA14 heat shock 70kDa protein 14
HSPB11 heat shock protein family B (small), member 11
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
ILF2 interleukin enhancer binding factor 2
ILF3 interleukin enhancer binding factor 3, 90kDa
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
JTB jumping translocation breakpoint
KANSL2 KAT8 regulatory NSL complex subunit 2
KARS lysyl-tRNA synthetase
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIAA0020 KIAA0020
KPNB1 karyopherin (importin) beta 1
LGTN ligatin
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYPLA1 lysophospholipase I
MCM2 minichromosome maintenance complex component 2
MCM7 minichromosome maintenance complex component 7
MRPL16 mitochondrial ribosomal protein L16
MRPL9 mitochondrial ribosomal protein L9
MTIF2 mitochondrial translational initiation factor 2
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
NACA nascent polypeptide-associated complex alpha subunit
NAE1 NEDD8 activating enzyme E1 subunit 1
NAP1L1 nucleosome assembly protein 1-like 1
NCL nucleolin
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae)
NOL11 nucleolar protein 11
NOL7 nucleolar protein 7, 27kDa
NONO non-POU domain containing, octamer-binding
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae)
NSUN5 NOP2/Sun domain family, member 5
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
NUP210 nucleoporin 210kDa
PABPN1 poly(A) binding protein, nuclear 1
PARK7 parkinson protein 7
PCNA proliferating cell nuclear antigen
PDAP1 PDGFA associated protein 1
PHB2 prohibitin 2
PMPCB peptidase (mitochondrial processing) beta
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit
POLR1D polymerase (RNA) I polypeptide D, 16kDa
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD)
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPIH peptidylprolyl isomerase H (cyclophilin H)
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRMT1 protein arginine methyltransferase 1
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTMA prothymosin, alpha
PUF60 poly-U binding splicing factor 60KDa
PWP1 PWP1 homolog (S. cerevisiae)
QARS glutaminyl-tRNA synthetase
RAD23A RAD23 homolog A (S. cerevisiae)
RALY RALY heterogeneous nuclear ribonucleoprotein
RAN RAN, member RAS oncogene family
RBBP4 retinoblastoma binding protein 4
RBBP6 retinoblastoma binding protein 6
RBM10 RNA binding motif protein 10
RBM12 RNA binding motif protein 12
RBM15 RNA binding motif protein 15
RBMX RNA binding motif protein, X-linked
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RNPS1 RNA binding protein S1, serine-rich domain
RPL10A ribosomal protein L10a
RPL12 ribosomal protein L12
RPL13 ribosomal protein L13
RPL13A ribosomal protein L13a
RPL14 ribosomal protein L14
RPL15 ribosomal protein L15
RPL17 ribosomal protein L17
RPL19 ribosomal protein L19
RPL22 ribosomal protein L22
RPL23A ribosomal protein L23a
RPL24 ribosomal protein L24
RPL27 ribosomal protein L27
RPL28 ribosomal protein L28
RPL29 ribosomal protein L29
RPL3 ribosomal protein L3
RPL32 ribosomal protein L32
RPL35 ribosomal protein L35
RPL35A ribosomal protein L35a
RPL36 ribosomal protein L36
RPL37 ribosomal protein L37
RPL38 ribosomal protein L38
RPL4 ribosomal protein L4
RPL5 ribosomal protein L5
RPL6 ribosomal protein L6
RPL7 ribosomal protein L7
RPL7A ribosomal protein L7a
RPL8 ribosomal protein L8
RPL9 ribosomal protein L9
RPS10 ribosomal protein S10
RPS12 ribosomal protein S12
RPS15 ribosomal protein S15
RPS16 ribosomal protein S16
RPS17 ribosomal protein S17
RPS19 ribosomal protein S19
RPS2 ribosomal protein S2
RPS20 ribosomal protein S20
RPS21 ribosomal protein S21
RPS23 ribosomal protein S23
RPS25 ribosomal protein S25
RPS29 ribosomal protein S29
RPS3 ribosomal protein S3
RPS4X ribosomal protein S4, X-linked
RPS6 ribosomal protein S6
RPS7 ribosomal protein S7
RPS8 ribosomal protein S8
RPSA ribosomal protein SA
RRP1B ribosomal RNA processing 1B
RSL1D1 ribosomal L1 domain containing 1
RUVBL2 RuvB-like AAA ATPase 2
SERBP1 SERPINE1 mRNA binding protein 1
SET SET nuclear proto-oncogene
SF1 splicing factor 1
SF3A2 splicing factor 3a, subunit 2, 66kDa
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC7A5P1 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRPA small nuclear ribonucleoprotein polypeptide A
SNRPA1 small nuclear ribonucleoprotein polypeptide A'
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa
SNRPE small nuclear ribonucleoprotein polypeptide E
SOD1 superoxide dismutase 1, soluble
SRRM1 serine/arginine repetitive matrix 1
SRSF1 serine/arginine-rich splicing factor 1
SRSF10 serine/arginine-rich splicing factor 10
SRSF2 serine/arginine-rich splicing factor 2
SRSF3 serine/arginine-rich splicing factor 3
SRSF7 serine/arginine-rich splicing factor 7
SRSF9 serine/arginine-rich splicing factor 9
SSBP1 single-stranded DNA binding protein 1, mitochondrial
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
STARD7 StAR-related lipid transfer (START) domain containing 7
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
SUZ12 SUZ12 polycomb repressive complex 2 subunit
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TARDBP TAR DNA binding protein
TBL3 transducin (beta)-like 3
TCERG1 transcription elongation regulator 1
TMEM147 transmembrane protein 147
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast)
TRA2B transformer 2 beta homolog (Drosophila)
TRIM28 tripartite motif containing 28
TUFM Tu translation elongation factor, mitochondrial
U2AF1 U2 small nuclear RNA auxiliary factor 1
U2SURP U2 snRNP-associated SURP domain containing
UBA2 ubiquitin-like modifier activating enzyme 2
UBE2I ubiquitin-conjugating enzyme E2I
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
UQCRH ubiquinol-cytochrome c reductase hinge protein
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
UXT ubiquitously-expressed, prefoldin-like chaperone
VDAC2 voltage-dependent anion channel 2
XPO1 exportin 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YBX1 Y box binding protein 1
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta