| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | F-box and leucine-rich repeat protein 20|Members of the F-box protein family, such as FBXL20, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] (NCBI Entrez Gene Database, 84961) |
| External Link | https://ncbi.nlm.nih.gov/gene/84961 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the FBXL20 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RTN2 | reticulon 2 | 0.0140783 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.0131669 |
| ATF3 | activating transcription factor 3 | 0.01156 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0105096 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00983885 |
| BCL2A1 | BCL2-related protein A1 | 0.00954755 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00936994 |
| RRAGD | Ras-related GTP binding D | 0.0092911 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.00883153 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00869433 |
| KRT23 | keratin 23, type I | 0.0086039 |
| TMSB15A | thymosin beta 15a | 0.00858593 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00829661 |
| FMO3 | flavin containing monooxygenase 3 | 0.00824244 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.00809611 |
| MAB21L1 | mab-21-like 1 (C. elegans) | 0.00792566 |
| E2F2 | E2F transcription factor 2 | 0.00784035 |
| MX1 | MX dynamin-like GTPase 1 | 0.00774459 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00762167 |
| RXYLT1 | ribitol xylosyltransferase 1 | 0.00760594 |
| SMAD3 | SMAD family member 3 | 0.00752422 |
| RND3 | Rho family GTPase 3 | 0.00747358 |
| DUSP2 | dual specificity phosphatase 2 | 0.00745048 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00742342 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00728897 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00722948 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00714662 |
| GTF3A | general transcription factor IIIA | 0.0070836 |
| NEBL | nebulette | 0.00689482 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00687833 |
| CYB561 | cytochrome b561 | 0.00687436 |
| IL1R1 | interleukin 1 receptor, type I | 0.00678081 |
| AK1 | adenylate kinase 1 | 0.00672602 |
| ASS1 | argininosuccinate synthase 1 | 0.00664046 |
| YME1L1 | YME1-like 1 ATPase | 0.00663726 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) | 0.0066198 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.00661618 |
| IFRD1 | interferon-related developmental regulator 1 | 0.00659225 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | 0.00658796 |
| USP6NL | USP6 N-terminal like | 0.00653656 |
| JUNB | jun B proto-oncogene | 0.00652421 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.00651788 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00650699 |
| IL1RN | interleukin 1 receptor antagonist | 0.00642297 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.00639124 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 0.00628456 |
| TESC | tescalcin | 0.0062842 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00627179 |
| DHDDS | dehydrodolichyl diphosphate synthase | 0.00624652 |
| PITX3 | paired-like homeodomain 3 | 0.00622763 |
| ATP13A3 | ATPase type 13A3 | 0.00621927 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00620706 |
| ARG1 | arginase 1 | 0.00619787 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.00616927 |
| XIC | X chromosome inactivation center | 0.006134 |
| PSCA | prostate stem cell antigen | 0.00613121 |
| PLBD1 | phospholipase B domain containing 1 | 0.00613097 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.00611408 |
| S100P | S100 calcium binding protein P | 0.00608909 |
| MSRB2 | methionine sulfoxide reductase B2 | 0.00608273 |
| IFI44 | interferon-induced protein 44 | 0.0060802 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | 0.00607642 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00606859 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.00606439 |
| MAB21L2 | mab-21-like 2 (C. elegans) | 0.00603466 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00602385 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00601936 |
| H1-0 | H1.0 linker histone | 0.00596516 |
| UBL3 | ubiquitin-like 3 | 0.00593784 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00590963 |
| ALB | albumin | 0.0058714 |
| MOSPD1 | motile sperm domain containing 1 | 0.00585406 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00584885 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.00579454 |
| MSLN | mesothelin | 0.00577369 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | 0.00576034 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.00570362 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00568223 |
| GCH1 | GTP cyclohydrolase 1 | 0.00567398 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00564401 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.00560921 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.00560409 |
| LCN2 | lipocalin 2 | 0.00556972 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.00556289 |
| TYRP1 | tyrosinase-related protein 1 | 0.00555462 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.00554886 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00554219 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 | 0.00553594 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00551754 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | 0.0055162 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0054977 |
| ZNF91 | zinc finger protein 91 | 0.00549631 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.00546561 |
| IFRD2 | interferon-related developmental regulator 2 | 0.00546549 |
| GNAS | GNAS complex locus | 0.00544475 |
| ORM1 | orosomucoid 1 | 0.0054307 |
| BEX4 | brain expressed, X-linked 4 | 0.00542718 |
| CTSE | cathepsin E | 0.00539319 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.00539059 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | 0.00538626 |
| PAH | phenylalanine hydroxylase | 0.00536986 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.00536179 |
| MMP12 | matrix metallopeptidase 12 | 0.00535713 |
| CLIC3 | chloride intracellular channel 3 | 0.00535056 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00533284 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 0.00532554 |
| BHMT | betaine--homocysteine S-methyltransferase | 0.0053057 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | 0.00529416 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.00528075 |
| RPIA | ribose 5-phosphate isomerase A | 0.0052759 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00526238 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0052219 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00521219 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00520719 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.00518094 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0051663 |
| NUP58 | nucleoporin 58 | 0.00514776 |
| PDLIM4 | PDZ and LIM domain 4 | 0.00511967 |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) | 0.0051133 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00510614 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00510157 |
| GPX7 | glutathione peroxidase 7 | 0.00509992 |
| IFI44L | interferon-induced protein 44-like | 0.00508568 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.00507961 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 0.00504306 |
| NAPA | N-ethylmaleimide-sensitive factor attachment protein, alpha | 0.00503481 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.00502363 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.00502132 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | 0.00501672 |
| MANSC1 | MANSC domain containing 1 | 0.00497822 |
| FBP1 | fructose-1,6-bisphosphatase 1 | 0.00495724 |
| STC2 | stanniocalcin 2 | 0.00495342 |
| DIPK1A | divergent protein kinase domain 1A | 0.00493905 |
| KCMF1 | potassium channel modulatory factor 1 | 0.00493552 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00490671 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00489157 |
| CRP | C-reactive protein, pentraxin-related | 0.00487835 |
| MMP8 | matrix metallopeptidase 8 | 0.00487107 |
| RNF13 | ring finger protein 13 | 0.00487063 |
| SGCE | sarcoglycan, epsilon | 0.00486883 |
| CCSER2 | coiled-coil serine-rich protein 2 | 0.00486871 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00486865 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.00486844 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00486207 |
| PRDX2 | peroxiredoxin 2 | 0.00485781 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | 0.00485572 |
| PRKD3 | protein kinase D3 | 0.00484996 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00484349 |
| VDAC2 | voltage-dependent anion channel 2 | 0.00483707 |
| ADM | adrenomedullin | 0.00482173 |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.00481561 |
| RGS4 | regulator of G-protein signaling 4 | 0.00481494 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.004814 |
| TMEM260 | transmembrane protein 260 | 0.00480964 |
| AUTS2 | autism susceptibility candidate 2 | 0.00478757 |
| KLF9 | Kruppel-like factor 9 | 0.00478317 |
| SPRR3 | small proline-rich protein 3 | 0.00477434 |
| RFK | riboflavin kinase | 0.00476549 |
| CAMP | cathelicidin antimicrobial peptide | 0.00475933 |
| RCAN1 | regulator of calcineurin 1 | 0.0047411 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | 0.00472863 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00471943 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00471429 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) | 0.00471366 |
| WSB2 | WD repeat and SOCS box containing 2 | 0.00471194 |
| ATP11B | ATPase, class VI, type 11B | 0.00469885 |
| PPL | periplakin | 0.00469862 |
| CAVIN3 | caveolae associated protein 3 | 0.00468938 |
| DCK | deoxycytidine kinase | 0.00466694 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00466309 |
| RADX | RPA1 related single stranded DNA binding protein, X-linked | 0.00465865 |
| MMP3 | matrix metallopeptidase 3 | 0.00465001 |
| DEFB4A | defensin, beta 4A | 0.00464388 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00463993 |
| ODC1 | ornithine decarboxylase 1 | 0.00463545 |
| RGS3 | regulator of G-protein signaling 3 | 0.00463338 |
| AHSG | alpha-2-HS-glycoprotein | 0.00462662 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 | 0.00462346 |
| TDG | thymine-DNA glycosylase | 0.00462322 |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) | 0.00461078 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.00460898 |
| ODAM | odontogenic, ameloblast asssociated | 0.00459738 |
| RGS5 | regulator of G-protein signaling 5 | 0.0045964 |
| MSRB1 | methionine sulfoxide reductase B1 | 0.00459424 |
| STOM | stomatin | 0.00458785 |
| CIRBP | cold inducible RNA binding protein | 0.00457092 |
| ZNF331 | zinc finger protein 331 | 0.00456584 |
| KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 | 0.00456393 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 | 0.00456188 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | 0.00456169 |
| MYL12B | myosin, light chain 12B, regulatory | 0.00455963 |
| CLC | Charcot-Leyden crystal galectin | 0.0045575 |
| RGS1 | regulator of G-protein signaling 1 | 0.00453254 |
| NOX4 | NADPH oxidase 4 | 0.00451906 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.00450092 |
| HBD | hemoglobin, delta | 0.0044916 |
| SHOX2 | short stature homeobox 2 | 0.0044904 |
| C9ORF3 | chromosome 9 open reading frame 3 | 0.00448243 |
| PER1 | period circadian clock 1 | 0.00447917 |
| F5 | coagulation factor V (proaccelerin, labile factor) | 0.00447073 |
| ALG5 | ALG5, dolichyl-phosphate beta-glucosyltransferase | 0.00446914 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.00446847 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.00446829 |
| VASH2 | vasohibin 2 | 0.00446545 |
| CUEDC2 | CUE domain containing 2 | 0.00445982 |
| GUK1 | guanylate kinase 1 | 0.00445594 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 0.00445344 |
| SLC38A4 | solute carrier family 38, member 4 | 0.00444671 |
| PON1 | paraoxonase 1 | 0.0044412 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.00443422 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 0.00443328 |
| AICDA | activation-induced cytidine deaminase | 0.0044269 |
| ZNF175 | zinc finger protein 175 | 0.00442584 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.00442213 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00439973 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.00439386 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.00438222 |
| OGFRL1 | opioid growth factor receptor-like 1 | 0.00437547 |
| EXOSC5 | exosome component 5 | 0.00436498 |
| GHITM | growth hormone inducible transmembrane protein | 0.00436317 |
| ACAA2 | acetyl-CoA acyltransferase 2 | 0.0043559 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.00433311 |
| ANXA1 | annexin A1 | 0.00433303 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.00432686 |
| MAP3K7CL | MAP3K7 C-terminal like | 0.00432505 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00432458 |
| ZNF83 | zinc finger protein 83 | 0.00431214 |
| WIF1 | WNT inhibitory factor 1 | 0.00431185 |
| ZIC1 | Zic family member 1 | 0.00429909 |
| EGR3 | early growth response 3 | 0.00429587 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | 0.00429061 |
| BPI | bactericidal/permeability-increasing protein | 0.00429037 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.00428538 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00428291 |
| LY75 | lymphocyte antigen 75 | 0.00428251 |
| XPOT | exportin, tRNA | 0.00427988 |
| SDC2 | syndecan 2 | 0.00427654 |
| CENPE | centromere protein E, 312kDa | 0.00427445 |
| EML1 | echinoderm microtubule associated protein like 1 | 0.00425908 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00425381 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.00424522 |
| SMAD4 | SMAD family member 4 | 0.0042422 |
| ATF4 | activating transcription factor 4 | 0.0042394 |
| MME | membrane metallo-endopeptidase | 0.00423051 |
| BUD31 | BUD31 homolog (S. cerevisiae) | 0.00422743 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | 0.00422589 |
| ANGPTL2 | angiopoietin-like 2 | 0.00422277 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0042224 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 | 0.00421883 |
| MDFIC | MyoD family inhibitor domain containing | 0.00421718 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL4A5 | collagen, type IV, alpha 5 | -0.015271 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.0121231 |
| STK10 | serine/threonine kinase 10 | -0.0120717 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.0118829 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.0114831 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0107819 |
| COL4A6 | collagen, type IV, alpha 6 | -0.0106617 |
| AGR2 | anterior gradient 2 | -0.0103568 |
| APOD | apolipoprotein D | -0.0103131 |
| ITM2C | integral membrane protein 2C | -0.0101387 |
| DSP | desmoplakin | -0.0100733 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00986103 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00980924 |
| C3 | complement component 3 | -0.0097565 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00934343 |
| PIP | prolactin-induced protein | -0.00914072 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00907054 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00892954 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00867059 |
| MAP7 | microtubule-associated protein 7 | -0.00851984 |
| CD99 | CD99 molecule | -0.00841047 |
| CDC42 | cell division cycle 42 | -0.00836856 |
| CPM | carboxypeptidase M | -0.00834595 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.0082953 |
| KRT17 | keratin 17, type I | -0.00828998 |
| KRT14 | keratin 14, type I | -0.00820194 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.0081742 |
| TPD52 | tumor protein D52 | -0.00815998 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00815834 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00810665 |
| PRNP | prion protein | -0.00802865 |
| BCHE | butyrylcholinesterase | -0.00802582 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00787723 |
| NXN | nucleoredoxin | -0.00774749 |
| GRB14 | growth factor receptor-bound protein 14 | -0.00767176 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00765976 |
| PRKCB | protein kinase C, beta | -0.00764795 |
| AEBP1 | AE binding protein 1 | -0.00755795 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.00751483 |
| FCGBP | Fc fragment of IgG binding protein | -0.00743063 |
| HAT1 | histone acetyltransferase 1 | -0.00742241 |
| PCDH9 | protocadherin 9 | -0.00738473 |
| MALL | mal, T-cell differentiation protein-like | -0.00731115 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00726766 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00726477 |
| RUNX3 | runt-related transcription factor 3 | -0.00722294 |
| ASRGL1 | asparaginase like 1 | -0.00719783 |
| TPP1 | tripeptidyl peptidase I | -0.00715638 |
| HOPX | HOP homeobox | -0.00714061 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0071381 |
| ITGB4 | integrin, beta 4 | -0.00713581 |
| ITGA6 | integrin, alpha 6 | -0.00713321 |
| CLCA2 | chloride channel accessory 2 | -0.00707711 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00704418 |
| EMP3 | epithelial membrane protein 3 | -0.00703475 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.00703301 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.00695674 |
| RRBP1 | ribosome binding protein 1 | -0.00689631 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | -0.00689404 |
| EZR | ezrin | -0.00688174 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | -0.00684823 |
| EPCAM | epithelial cell adhesion molecule | -0.00682756 |
| BRD4 | bromodomain containing 4 | -0.00679624 |
| GPM6A | glycoprotein M6A | -0.00676962 |
| STIP1 | stress-induced phosphoprotein 1 | -0.00675213 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00661041 |
| KRT6A | keratin 6A, type II | -0.00660638 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00658317 |
| MSX1 | msh homeobox 1 | -0.00656222 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | -0.00651937 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00647734 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00647143 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00647053 |
| COMP | cartilage oligomeric matrix protein | -0.00637358 |
| C7 | complement component 7 | -0.00633558 |
| P2RX1 | purinergic receptor P2X, ligand gated ion channel, 1 | -0.00632507 |
| BAG3 | BCL2-associated athanogene 3 | -0.00629947 |
| CA2 | carbonic anhydrase II | -0.00629651 |
| MTA1 | metastasis associated 1 | -0.00628846 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00625806 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00625528 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.00623431 |
| CHKB | choline kinase beta | -0.00619144 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00619078 |
| CLU | clusterin | -0.00617397 |
| FASN | fatty acid synthase | -0.006172 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.00613435 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00610813 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.00607305 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | -0.00605902 |
| PDGFD | platelet derived growth factor D | -0.00603112 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | -0.00601519 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00597732 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00597443 |
| EAF2 | ELL associated factor 2 | -0.00596682 |
| THBS1 | thrombospondin 1 | -0.00595275 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00594604 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00594423 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.00592571 |
| RAPSN | receptor-associated protein of the synapse | -0.00589324 |
| NPC2 | Niemann-Pick disease, type C2 | -0.00588914 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00587901 |
| PMP22 | peripheral myelin protein 22 | -0.00586699 |
| POU2AF1 | POU class 2 associating factor 1 | -0.00584274 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.00582245 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | -0.00578011 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 | -0.00577404 |
| S100A10 | S100 calcium binding protein A10 | -0.00575596 |
| FAM198B | family with sequence similarity 198, member B | -0.00575303 |
| CNOT6 | CCR4-NOT transcription complex, subunit 6 | -0.00573674 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00572987 |
| CD93 | CD93 molecule | -0.00572573 |
| FBLN1 | fibulin 1 | -0.00571287 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.00570293 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00570284 |
| ACTB | actin, beta | -0.00568074 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0056725 |
| LAPTM5 | lysosomal protein transmembrane 5 | -0.00563285 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00562481 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.00561739 |
| PRKCZ | protein kinase C, zeta | -0.00561238 |
| SC5D | sterol-C5-desaturase | -0.00560261 |
| GLRX | glutaredoxin (thioltransferase) | -0.00558382 |
| COL4A2 | collagen, type IV, alpha 2 | -0.00551204 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00550728 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.00550341 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00550291 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00547804 |
| GIMAP6 | GTPase, IMAP family member 6 | -0.00545274 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | -0.00544652 |
| A2M | alpha-2-macroglobulin | -0.00544139 |
| RDX | radixin | -0.00543033 |
| NUTF2 | nuclear transport factor 2 | -0.00542744 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | -0.00541122 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.00539004 |
| CCL21 | chemokine (C-C motif) ligand 21 | -0.00538573 |
| PODXL | podocalyxin-like | -0.00533978 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00532733 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | -0.00532269 |
| EDNRA | endothelin receptor type A | -0.00530334 |
| SDC3 | syndecan 3 | -0.00529945 |
| SYT1 | synaptotagmin I | -0.00528731 |
| APLNR | apelin receptor | -0.00528337 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.00527803 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.00527039 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00525891 |
| SORD | sorbitol dehydrogenase | -0.00525677 |
| VDAC1 | voltage-dependent anion channel 1 | -0.00525378 |
| PNMA1 | paraneoplastic Ma antigen 1 | -0.0052351 |
| CSTA | cystatin A (stefin A) | -0.00522506 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | -0.00522302 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.00522109 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00521998 |
| CHRDL1 | chordin-like 1 | -0.00521417 |
| TGFB1 | transforming growth factor, beta 1 | -0.00520501 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0051904 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00519036 |
| NLRP2 | NLR family, pyrin domain containing 2 | -0.00518448 |
| RCAN2 | regulator of calcineurin 2 | -0.00516761 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00516011 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | -0.00515669 |
| OLFM4 | olfactomedin 4 | -0.00515295 |
| NDNF | neuron-derived neurotrophic factor | -0.00514393 |
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | -0.00514022 |
| CALD1 | caldesmon 1 | -0.00513521 |
| S100B | S100 calcium binding protein B | -0.00512798 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 | -0.00512728 |
| CCND2 | cyclin D2 | -0.00512685 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 | -0.00511579 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | -0.00511336 |
| FBN2 | fibrillin 2 | -0.00510509 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.00510354 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00509578 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | -0.00509039 |
| FLNA | filamin A, alpha | -0.00508727 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | -0.0050729 |
| RXRA | retinoid X receptor, alpha | -0.0050722 |
| AHNAK | AHNAK nucleoprotein | -0.00506845 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00505525 |
| CSRP1 | cysteine and glycine-rich protein 1 | -0.00505187 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00504952 |
| LY86 | lymphocyte antigen 86 | -0.00504587 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00504225 |
| AOC3 | amine oxidase, copper containing 3 | -0.00504202 |
| RIN2 | Ras and Rab interactor 2 | -0.0050322 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit | -0.00502179 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00502015 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.00502003 |
| CFD | complement factor D (adipsin) | -0.00501892 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.00500846 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00500619 |
| RESF1 | retroelement silencing factor 1 | -0.00500193 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.00500013 |
| GAS7 | growth arrest-specific 7 | -0.00499404 |
| LMNB1 | lamin B1 | -0.00499087 |
| FN1 | fibronectin 1 | -0.00498704 |
| HOXB6 | homeobox B6 | -0.00496977 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.00496616 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | -0.00495864 |
| HOXB7 | homeobox B7 | -0.00494533 |
| MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | -0.0049243 |
| PON2 | paraoxonase 2 | -0.00492258 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | -0.00488981 |
| VSNL1 | visinin-like 1 | -0.00488935 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00488263 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00487596 |
| NKX2-2 | NK2 homeobox 2 | -0.0048694 |
| NEFH | neurofilament, heavy polypeptide | -0.00486928 |
| CPOX | coproporphyrinogen oxidase | -0.00486574 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00485343 |
| FAM3C | family with sequence similarity 3, member C | -0.00484858 |
| HSPE1 | heat shock 10kDa protein 1 | -0.00484848 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | -0.00483754 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00483282 |
| ACACA | acetyl-CoA carboxylase alpha | -0.00482833 |
| STK17A | serine/threonine kinase 17a | -0.00482169 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00480083 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -0.00480022 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.0047957 |
| TSPAN13 | tetraspanin 13 | -0.00478043 |
| PKP2 | plakophilin 2 | -0.00477489 |
| SDHAP1 | succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1 | -0.00477143 |
| ADCY7 | adenylate cyclase 7 | -0.00476391 |
| CD86 | CD86 molecule | -0.0047536 |
| ACLY | ATP citrate lyase | -0.00474941 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.00472909 |
| PKP3 | plakophilin 3 | -0.00472783 |
| CNTN1 | contactin 1 | -0.00472639 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00472479 |
| HDAC4 | histone deacetylase 4 | -0.00471702 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00470529 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | -0.00469899 |
| CDC20 | cell division cycle 20 | -0.00468967 |
| PLEC | plectin | -0.00468952 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00468131 |
| AK4 | adenylate kinase 4 | -0.00467768 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.00467766 |
| MLXIP | MLX interacting protein | -0.00465524 |
| GFAP | glial fibrillary acidic protein | -0.0046464 |
| IFNGR1 | interferon gamma receptor 1 | -0.00463528 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | -0.00463428 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00463204 |
| TMEM131 | transmembrane protein 131 | -0.00462926 |
| S100A2 | S100 calcium binding protein A2 | -0.00461141 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | -0.00460504 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00460274 |
| PYGL | phosphorylase, glycogen, liver | -0.00459301 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00459178 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | -0.00458379 |
