| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | F-box protein 11|This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It can function as an arginine methyltransferase that symmetrically dimethylates arginine residues, and it acts as an adaptor protein to mediate the neddylation of p53, which leads to the suppression of p53 function. This gene is known to be down-regulated in melanocytes from patients with vitiligo, a skin disorder that results in depigmentation. Polymorphisms in this gene are associated with chronic otitis media with effusion and recurrent otitis media (COME/ROM), a hearing loss disorder, and the knockout of the homologous mouse gene results in the deaf mouse mutant Jeff (Jf), a single gene model of otitis media. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010] (NCBI Entrez Gene Database, 80204) |
| External Link | https://ncbi.nlm.nih.gov/gene/80204 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the FBXO11 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TUBB6 | tubulin, beta 6 class V | 0.0203867 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.0121256 |
| CA2 | carbonic anhydrase II | 0.0114464 |
| RGCC | regulator of cell cycle | 0.0113362 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0111111 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | 0.0110905 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.0110827 |
| ADM | adrenomedullin | 0.0107148 |
| SIRT3 | sirtuin 3 | 0.0101878 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0100491 |
| TUBB2A | tubulin, beta 2A class IIa | 0.0100167 |
| PLS3 | plastin 3 | 0.00969378 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00964065 |
| GAS1 | growth arrest-specific 1 | 0.00957661 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00955799 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00937441 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0090356 |
| TPD52L1 | tumor protein D52-like 1 | 0.00897314 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00893451 |
| KRT14 | keratin 14, type I | 0.00878685 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00871593 |
| CCN2 | cellular communication network factor 2 | 0.00859096 |
| ANXA1 | annexin A1 | 0.0085408 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.0085107 |
| MT1E | metallothionein 1E | 0.00822989 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00808432 |
| KRT15 | keratin 15, type I | 0.00803563 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00802485 |
| ESR1 | estrogen receptor 1 | 0.00784887 |
| KRT5 | keratin 5, type II | 0.00781189 |
| LOXL1 | lysyl oxidase-like 1 | 0.00777182 |
| CRYAB | crystallin, alpha B | 0.00770776 |
| PERP | PERP, TP53 apoptosis effector | 0.00769558 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00763956 |
| BLNK | B-cell linker | 0.00761049 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00756887 |
| CALML3 | calmodulin-like 3 | 0.00744655 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00743486 |
| CD9 | CD9 molecule | 0.00727065 |
| CAV2 | caveolin 2 | 0.00722125 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 0.00711638 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00694716 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00692824 |
| DEFB1 | defensin, beta 1 | 0.0069224 |
| CCNG2 | cyclin G2 | 0.0068959 |
| KRT23 | keratin 23, type I | 0.00689132 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00680796 |
| HBD | hemoglobin, delta | 0.00680111 |
| VNN1 | vanin 1 | 0.00677566 |
| BLVRB | biliverdin reductase B | 0.00676283 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00675621 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00670068 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00666543 |
| PALMD | palmdelphin | 0.00659531 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.0065103 |
| COL6A3 | collagen, type VI, alpha 3 | 0.00648422 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00646817 |
| FRMD4B | FERM domain containing 4B | 0.00645896 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00644701 |
| CCNC | cyclin C | 0.00642915 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.00641723 |
| RHCG | Rh family, C glycoprotein | 0.0063853 |
| MT1G | metallothionein 1G | 0.00638006 |
| RANBP9 | RAN binding protein 9 | 0.00634406 |
| ASPN | asporin | 0.0063171 |
| MMP11 | matrix metallopeptidase 11 | 0.00627878 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00623571 |
| TPBG | trophoblast glycoprotein | 0.00623395 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00623205 |
| CP | ceruloplasmin (ferroxidase) | 0.00619278 |
| MFAP5 | microfibrillar associated protein 5 | 0.00618336 |
| KRT6B | keratin 6B, type II | 0.00617809 |
| DUSP5 | dual specificity phosphatase 5 | 0.00617749 |
| FST | follistatin | 0.00612457 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00611489 |
| COG7 | component of oligomeric golgi complex 7 | 0.00609565 |
| CSTA | cystatin A (stefin A) | 0.00608646 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.0060589 |
| STOM | stomatin | 0.00603137 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00598906 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.00595932 |
| MT1X | metallothionein 1X | 0.00595736 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.0059497 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00589035 |
| DSG3 | desmoglein 3 | 0.00588923 |
| PTK2 | protein tyrosine kinase 2 | 0.00587222 |
| EFHD1 | EF-hand domain family, member D1 | 0.00584855 |
| OAT | ornithine aminotransferase | 0.0058253 |
| MT1HL1 | metallothionein 1H-like 1 | 0.0058129 |
| RND3 | Rho family GTPase 3 | 0.0057882 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | 0.00573627 |
| S100A14 | S100 calcium binding protein A14 | 0.00573144 |
| RCAN1 | regulator of calcineurin 1 | 0.00572024 |
| RAB38 | RAB38, member RAS oncogene family | 0.00571354 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.00570851 |
| H1-2 | H1.2 linker histone, cluster member | 0.00569913 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | 0.00569551 |
| PPL | periplakin | 0.0056662 |
| CLDND1 | claudin domain containing 1 | 0.00564154 |
| RIOK3 | RIO kinase 3 | 0.00563965 |
| STK17A | serine/threonine kinase 17a | 0.00563817 |
| KLF6 | Kruppel-like factor 6 | 0.00563652 |
| FBLN2 | fibulin 2 | 0.00562164 |
| SIAH2 | siah E3 ubiquitin protein ligase 2 | 0.00561679 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0056102 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | 0.00559997 |
| BTG3 | BTG family, member 3 | 0.00558797 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) | 0.0055799 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 | 0.0055489 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00554699 |
| CRCT1 | cysteine-rich C-terminal 1 | 0.00552207 |
| WBP5 | WW domain binding protein 5 | 0.00550904 |
| RNF11 | ring finger protein 11 | 0.00549269 |
| RHOH | ras homolog family member H | 0.00547287 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G | 0.00545916 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.00544615 |
| KLK10 | kallikrein-related peptidase 10 | 0.00544019 |
| MRPS16 | mitochondrial ribosomal protein S16 | 0.00543177 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00541933 |
| MT1H | metallothionein 1H | 0.00541668 |
| RBM47 | RNA binding motif protein 47 | 0.00541618 |
| PXDN | peroxidasin | 0.00540888 |
| TAGLN | transgelin | 0.00540499 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00540475 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.0054043 |
| CCNA2 | cyclin A2 | 0.00538867 |
| FN1 | fibronectin 1 | 0.00537777 |
| RIDA | reactive intermediate imine deaminase A homolog | 0.0053675 |
| MIR22HG | MIR22 host gene | 0.00536079 |
| PLAU | plasminogen activator, urokinase | 0.00535693 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00534003 |
| ZNF91 | zinc finger protein 91 | 0.005312 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00530617 |
| S100A7 | S100 calcium binding protein A7 | 0.00529408 |
| PEG10 | paternally expressed 10 | 0.00528943 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.00528327 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0052791 |
| DAXX | death-domain associated protein | 0.00526742 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00525926 |
| LYZ | lysozyme | 0.00525577 |
| IFI44L | interferon-induced protein 44-like | 0.005247 |
| XPO7 | exportin 7 | 0.0052285 |
| EAF2 | ELL associated factor 2 | 0.00522571 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00522038 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00521516 |
| PEG3 | paternally expressed 3 | 0.00520918 |
| AMOTL2 | angiomotin like 2 | 0.00520238 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00519184 |
| ALAS2 | 5'-aminolevulinate synthase 2 | 0.00518204 |
| AHSP | alpha hemoglobin stabilizing protein | 0.00517628 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00517294 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.0051705 |
| H1-0 | H1.0 linker histone | 0.00516441 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00516093 |
| MCOLN1 | mucolipin 1 | 0.00514985 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.00514285 |
| SDC1 | syndecan 1 | 0.00514164 |
| TGM1 | transglutaminase 1 | 0.00513884 |
| S100A9 | S100 calcium binding protein A9 | 0.00513716 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.00513082 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00512561 |
| DAPK1 | death-associated protein kinase 1 | 0.00512274 |
| PLK2 | polo-like kinase 2 | 0.0051213 |
| SLC43A3 | solute carrier family 43, member 3 | 0.00512083 |
| MT1F | metallothionein 1F | 0.00510031 |
| PDCD10 | programmed cell death 10 | 0.00508688 |
| CLTB | clathrin, light chain B | 0.00507711 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | 0.00507312 |
| INSR | insulin receptor | 0.00506111 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00505247 |
| CTSC | cathepsin C | 0.00503228 |
| TXN | thioredoxin | 0.00501209 |
| KLK7 | kallikrein-related peptidase 7 | 0.00500141 |
| ARG2 | arginase 2 | 0.00499401 |
| CDC37L1 | cell division cycle 37-like 1 | 0.00499319 |
| PLIN3 | perilipin 3 | 0.00498366 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00494188 |
| LEPROT | leptin receptor overlapping transcript | 0.00493473 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.00491597 |
| FRZB | frizzled-related protein | 0.00491484 |
| VTN | vitronectin | 0.00491325 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0049116 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | 0.0048914 |
| CRNN | cornulin | 0.00487811 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00487614 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00487332 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00485721 |
| RAB7A | RAB7A, member RAS oncogene family | 0.00484398 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00481419 |
| SIX1 | SIX homeobox 1 | 0.00480761 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.00479562 |
| FGF13 | fibroblast growth factor 13 | 0.00479478 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.0047891 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | 0.00478591 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.00478364 |
| ZNF706 | zinc finger protein 706 | 0.00477828 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0047616 |
| LUM | lumican | 0.0047599 |
| PDLIM3 | PDZ and LIM domain 3 | 0.00475457 |
| DSE | dermatan sulfate epimerase | 0.00475328 |
| MXRA8 | matrix-remodelling associated 8 | 0.00474886 |
| YIPF6 | Yip1 domain family, member 6 | 0.00473353 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00473282 |
| CPE | carboxypeptidase E | 0.00471868 |
| BEX4 | brain expressed, X-linked 4 | 0.00471405 |
| SELENOT | selenoprotein T | 0.00471177 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 0.00469462 |
| DCN | decorin | 0.00463461 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit | 0.00462737 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.00462481 |
| ADK | adenosine kinase | 0.00461806 |
| ALDOB | aldolase B, fructose-bisphosphate | 0.0046079 |
| TPM2 | tropomyosin 2 (beta) | 0.00460652 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.00460219 |
| DBP | D site of albumin promoter (albumin D-box) binding protein | 0.00458598 |
| SPRR1A | small proline-rich protein 1A | 0.00458427 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.00457114 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.00456677 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | 0.00456271 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00455912 |
| MZB1 | marginal zone B and B1 cell-specific protein | 0.00455781 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.00453919 |
| DUSP1 | dual specificity phosphatase 1 | 0.00453849 |
| PLXNC1 | plexin C1 | 0.00452376 |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.00452339 |
| SPRR1B | small proline-rich protein 1B | 0.00452258 |
| PLIN1 | perilipin 1 | 0.00450907 |
| SEC61B | Sec61 beta subunit | 0.00450407 |
| MDFIC | MyoD family inhibitor domain containing | 0.00450305 |
| ABI1 | abl-interactor 1 | 0.00449963 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00449857 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00449715 |
| PLEK | pleckstrin | 0.0044963 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00449442 |
| KRT17 | keratin 17, type I | 0.00447866 |
| G0S2 | G0/G1 switch 2 | 0.00446795 |
| MMP9 | matrix metallopeptidase 9 | 0.00446159 |
| MCL1 | myeloid cell leukemia 1 | 0.00445876 |
| CYP11A1 | cytochrome P450, family 11, subfamily A, polypeptide 1 | 0.00445293 |
| GLTP | glycolipid transfer protein | 0.00445233 |
| ANXA2P2 | annexin A2 pseudogene 2 | 0.00445005 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00444013 |
| WDR26 | WD repeat domain 26 | 0.00444001 |
| TFDP1 | transcription factor Dp-1 | 0.00442467 |
| ASPH | aspartate beta-hydroxylase | 0.00442408 |
| OXTR | oxytocin receptor | 0.00441854 |
| SEPTIN10 | septin 10 | 0.00440345 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.00440324 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.00439992 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | 0.00439939 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AGR2 | anterior gradient 2 | -0.0123448 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.0120226 |
| MAGEA3 | melanoma antigen family A3 | -0.0116823 |
| GNAS | GNAS complex locus | -0.0115066 |
| SMC1A | structural maintenance of chromosomes 1A | -0.0106461 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00979803 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.00975837 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00971115 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00945507 |
| OLFM4 | olfactomedin 4 | -0.00930892 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00905828 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00896481 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -0.00883991 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00833121 |
| GPX2 | glutathione peroxidase 2 | -0.00828959 |
| PLAT | plasminogen activator, tissue | -0.00823274 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.00815007 |
| JADE2 | jade family PHD finger 2 | -0.00806149 |
| MAGED1 | melanoma antigen family D1 | -0.0078951 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.00787302 |
| PRKCA | protein kinase C, alpha | -0.00751154 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00738958 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00727521 |
| CST3 | cystatin C | -0.00719163 |
| TGM2 | transglutaminase 2 | -0.00716574 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00714009 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00711495 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.00701992 |
| MSLN | mesothelin | -0.0069411 |
| SATB2 | SATB homeobox 2 | -0.00693027 |
| IL7R | interleukin 7 receptor | -0.00691333 |
| TXNIP | thioredoxin interacting protein | -0.00691117 |
| SCG5 | secretogranin V | -0.00684465 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.00683391 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00682084 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | -0.00662411 |
| SOCS2 | suppressor of cytokine signaling 2 | -0.00657363 |
| CNR1 | cannabinoid receptor 1 (brain) | -0.00656532 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00650942 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.00650841 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.00644123 |
| CSRP1 | cysteine and glycine-rich protein 1 | -0.00637839 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.00628846 |
| CCNB1 | cyclin B1 | -0.00622002 |
| FABP6 | fatty acid binding protein 6, ileal | -0.00609708 |
| KRT20 | keratin 20, type I | -0.00606542 |
| EPHB2 | EPH receptor B2 | -0.00603254 |
| PRAME | preferentially expressed antigen in melanoma | -0.00599302 |
| GPA33 | glycoprotein A33 (transmembrane) | -0.00596333 |
| NRCAM | neuronal cell adhesion molecule | -0.00596225 |
| TNIK | TRAF2 and NCK interacting kinase | -0.00595542 |
| DMBT1 | deleted in malignant brain tumors 1 | -0.00593055 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00592477 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00590907 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0058978 |
| DNM1L | dynamin 1-like | -0.0058339 |
| IFI30 | interferon, gamma-inducible protein 30 | -0.00583265 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.00576653 |
| EPHA4 | EPH receptor A4 | -0.00576233 |
| CLCA1 | chloride channel accessory 1 | -0.00575368 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00569143 |
| EDN3 | endothelin 3 | -0.00567508 |
| HSPA8 | heat shock 70kDa protein 8 | -0.00565171 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | -0.00564831 |
| EFNB2 | ephrin-B2 | -0.00564585 |
| FLOT2 | flotillin 2 | -0.00563436 |
| HPCAL1 | hippocalcin-like 1 | -0.00562005 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00560645 |
| PENK | proenkephalin | -0.00558588 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 | -0.00553763 |
| GUSB | glucuronidase, beta | -0.00551742 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | -0.00547827 |
| MLPH | melanophilin | -0.0054605 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.00541857 |
| TSPAN8 | tetraspanin 8 | -0.00541385 |
| TKTL1 | transketolase-like 1 | -0.00541017 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.00540058 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00538044 |
| SRGN | serglycin | -0.00537465 |
| SPATA20 | spermatogenesis associated 20 | -0.00534438 |
| FAR2 | fatty acyl CoA reductase 2 | -0.00534202 |
| HNMT | histamine N-methyltransferase | -0.00529113 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | -0.00528425 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00526622 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.00526435 |
| COL4A6 | collagen, type IV, alpha 6 | -0.00526265 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00524664 |
| FABP7 | fatty acid binding protein 7, brain | -0.00523559 |
| ADD3 | adducin 3 (gamma) | -0.00520797 |
| G6PD | glucose-6-phosphate dehydrogenase | -0.00519672 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00518424 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | -0.00517018 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | -0.00516851 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.00511903 |
| PLCB4 | phospholipase C, beta 4 | -0.00509392 |
| EFHD2 | EF-hand domain family, member D2 | -0.00508894 |
| GFAP | glial fibrillary acidic protein | -0.0050665 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase | -0.00505964 |
| COL9A3 | collagen, type IX, alpha 3 | -0.00499785 |
| SRI | sorcin | -0.00497923 |
| ITPKB | inositol-trisphosphate 3-kinase B | -0.00497487 |
| GALC | galactosylceramidase | -0.00496469 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | -0.0049616 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.00495201 |
| TGOLN2 | trans-golgi network protein 2 | -0.00493584 |
| MTMR11 | myotubularin related protein 11 | -0.00493388 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00493287 |
| AGA | aspartylglucosaminidase | -0.004917 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | -0.00491507 |
| ANXA4 | annexin A4 | -0.00490255 |
| METRN | meteorin, glial cell differentiation regulator | -0.00486447 |
| MGST2 | microsomal glutathione S-transferase 2 | -0.0048367 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00481918 |
| KRT8 | keratin 8, type II | -0.00479351 |
| CIRBP | cold inducible RNA binding protein | -0.00477857 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.00477222 |
| TSKU | tsukushi, small leucine rich proteoglycan | -0.00476338 |
| S100P | S100 calcium binding protein P | -0.00476013 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00475309 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00475228 |
| GOLIM4 | golgi integral membrane protein 4 | -0.00475012 |
| USP48 | ubiquitin specific peptidase 48 | -0.00474851 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00474767 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.00473839 |
| AQP4 | aquaporin 4 | -0.0047334 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.00471875 |
| CTSK | cathepsin K | -0.00470866 |
| TBC1D5 | TBC1 domain family, member 5 | -0.00468967 |
| PIP4K2C | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma | -0.00466465 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.00464885 |
| SAMM50 | SAMM50 sorting and assembly machinery component | -0.00464022 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00462706 |
| H2AX | H2A.X variant histone | -0.00460694 |
| REG3A | regenerating islet-derived 3 alpha | -0.00460151 |
| SSX1 | synovial sarcoma, X breakpoint 1 | -0.00460113 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | -0.00459086 |
| BMP7 | bone morphogenetic protein 7 | -0.00459076 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -0.00458323 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00457449 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00457438 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.00455756 |
| MANSC1 | MANSC domain containing 1 | -0.00455693 |
| NEFH | neurofilament, heavy polypeptide | -0.00454684 |
| DPY19L2P2 | DPY19L2 pseudogene 2 | -0.004523 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00450539 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00450325 |
| KRT7 | keratin 7, type II | -0.00447516 |
| TRIM68 | tripartite motif containing 68 | -0.00447365 |
| LDHB | lactate dehydrogenase B | -0.00446977 |
| MAGEA12 | melanoma antigen family A12 | -0.00446871 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00446475 |
| VIPR1 | vasoactive intestinal peptide receptor 1 | -0.00445963 |
| TST | thiosulfate sulfurtransferase (rhodanese) | -0.00445591 |
| PRKCSH | protein kinase C substrate 80K-H | -0.00444669 |
| SFTPD | surfactant protein D | -0.00443881 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00442962 |
| TRAF5 | TNF receptor-associated factor 5 | -0.00442819 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.00442575 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | -0.00440861 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | -0.00440746 |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 | -0.00440496 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.00437585 |
| LARS2 | leucyl-tRNA synthetase 2, mitochondrial | -0.00435856 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00435632 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | -0.0043457 |
| GOLGA8A | golgin A8 family, member A | -0.00434204 |
| COL9A2 | collagen, type IX, alpha 2 | -0.00434062 |
| SYNGR3 | synaptogyrin 3 | -0.00433549 |
| STXBP6 | syntaxin binding protein 6 (amisyn) | -0.00433303 |
| KCTD14 | potassium channel tetramerization domain containing 14 | -0.00432493 |
| SFTPA2 | surfactant protein A2 | -0.00432114 |
| CNTNAP2 | contactin associated protein-like 2 | -0.00432023 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0043128 |
| RELA | v-rel avian reticuloendotheliosis viral oncogene homolog A | -0.00430488 |
| COQ8A | coenzyme Q8A | -0.00429063 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | -0.00428173 |
| SRSF6 | serine/arginine-rich splicing factor 6 | -0.00427744 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00427518 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | -0.00426551 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00426407 |
| ELAPOR1 | endosome-lysosome associated apoptosis and autophagy regulator 1 | -0.00425799 |
| ARF3 | ADP-ribosylation factor 3 | -0.00425687 |
| DLX2 | distal-less homeobox 2 | -0.00425674 |
| KIAA1644 | KIAA1644 | -0.0042546 |
| TLE4 | transducin-like enhancer of split 4 | -0.00423825 |
| C11ORF49 | chromosome 11 open reading frame 49 | -0.00423747 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.00423734 |
| SFTPB | surfactant protein B | -0.00422636 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00422227 |
| DEFA6 | defensin, alpha 6, Paneth cell-specific | -0.00421617 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.00421245 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.00421193 |
| FOXM1 | forkhead box M1 | -0.00419968 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | -0.00419011 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0041885 |
| C1ORF216 | chromosome 1 open reading frame 216 | -0.0041876 |
| CRH | corticotropin releasing hormone | -0.00416679 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.00416152 |
| POF1B | premature ovarian failure, 1B | -0.00415828 |
| CASC3 | cancer susceptibility candidate 3 | -0.00415065 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.00414777 |
| MAOA | monoamine oxidase A | -0.00414308 |
| TFF1 | trefoil factor 1 | -0.00413716 |
| TAGLN2 | transgelin 2 | -0.00413513 |
| ICAM2 | intercellular adhesion molecule 2 | -0.00413209 |
| DGKZ | diacylglycerol kinase, zeta | -0.00412372 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | -0.00411899 |
| PIR | pirin (iron-binding nuclear protein) | -0.00410703 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.00410674 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.00410372 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.00409001 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | -0.00407922 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00406662 |
| NDUFS2 | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) | -0.0040657 |
| ASB9 | ankyrin repeat and SOCS box containing 9 | -0.0040656 |
| GPM6A | glycoprotein M6A | -0.00406275 |
| TSC22D1 | TSC22 domain family, member 1 | -0.00406116 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 | -0.00405791 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.00405686 |
| PFKL | phosphofructokinase, liver | -0.0040546 |
| VAMP3 | vesicle-associated membrane protein 3 | -0.0040387 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00403802 |
| EPN2 | epsin 2 | -0.00402394 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00402303 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00401756 |
| SYNM | synemin, intermediate filament protein | -0.0040149 |
| CYTH1 | cytohesin 1 | -0.0040083 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.0040061 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.00400448 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | -0.00398715 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 | -0.00398226 |
| SIKE1 | suppressor of IKBKE 1 | -0.00397308 |
| XYLT1 | xylosyltransferase I | -0.00396245 |
| PRPF6 | pre-mRNA processing factor 6 | -0.00395413 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | -0.00394648 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | -0.00393821 |
| LRRC47 | leucine rich repeat containing 47 | -0.00393407 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.00392345 |
| NOX1 | NADPH oxidase 1 | -0.0039221 |
| TRIM38 | tripartite motif containing 38 | -0.00391787 |
| KLF2 | Kruppel-like factor 2 | -0.00391633 |
| PRSS21 | protease, serine, 21 (testisin) | -0.00391366 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.00391356 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00391116 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.00390995 |
| GSTK1 | glutathione S-transferase kappa 1 | -0.00389062 |
| MAGEA11 | melanoma antigen family A11 | -0.00386773 |
| MAP3K11 | mitogen-activated protein kinase kinase kinase 11 | -0.0038555 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00385524 |
