FBXO7 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description F-box protein 7|This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 25793)
External Link http://www.ncbi.nlm.nih.gov/gene/25793
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Genes

75 interacting proteins for FBXO7 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
BIRC2 baculoviral IAP repeat containing 2
BTBD1 BTB (POZ) domain containing 1
BTBD2 BTB (POZ) domain containing 2
BTBD9 BTB (POZ) domain containing 9
CCND1 cyclin D1
CCND3 cyclin D3
CDC34 cell division cycle 34
CDK6 cyclin-dependent kinase 6
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CKS1B CDC28 protein kinase regulatory subunit 1B
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
COPS2 COP9 signalosome subunit 2
COPS3 COP9 signalosome subunit 3
COPS4 COP9 signalosome subunit 4
COPS5 COP9 signalosome subunit 5
COPS6 COP9 signalosome subunit 6
COPS7A COP9 signalosome subunit 7A
COPS7B COP9 signalosome subunit 7B
COPS8 COP9 signalosome subunit 8
CRBN cereblon
CUL1 cullin 1
CUL2 cullin 2
CUL3 cullin 3
CUL4A cullin 4A
CUL4B cullin 4B
CUL5 cullin 5
DCAF11 DDB1 and CUL4 associated factor 11
DCAF4 DDB1 and CUL4 associated factor 4
DDA1 DET1 and DDB1 associated 1
DDB2 damage-specific DNA binding protein 2, 48kDa
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
ELF4 E74-like factor 4 (ets domain transcription factor)
ERCC8 excision repair cross-complementation group 8
FBXO11 F-box protein 11
FBXO17 F-box protein 17
FBXO22 F-box protein 22
FBXO44 F-box protein 44
FBXW9 F-box and WD repeat domain containing 9
FEM1B fem-1 homolog b (C. elegans)
GPS1 G protein pathway suppressor 1
KCTD3 potassium channel tetramerization domain containing 3
KLHL13 kelch-like family member 13
KLHL15 kelch-like family member 15
KLHL20 kelch-like family member 20
KLHL22 kelch-like family member 22
KLHL24 kelch-like family member 24
KLHL42 kelch-like family member 42
KLHL8 kelch-like family member 8
KLHL9 kelch-like family member 9
LRR1 leucine rich repeat protein 1
LRRC14 leucine rich repeat containing 14
MAGED1 melanoma antigen family D1
MYEOV2 myeloma overexpressed 2
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NRF1 nuclear respiratory factor 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PINK1 PTEN induced putative kinase 1
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
RBBP6 retinoblastoma binding protein 6
RBX1 ring-box 1, E3 ubiquitin protein ligase
SEC24C SEC24 family member C
SHFM1 split hand/foot malformation (ectrodactyly) type 1
SHKBP1 SH3KBP1 binding protein 1
SKP1 S-phase kinase-associated protein 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
TOR1AIP2 torsin A interacting protein 2
TRAF2 TNF receptor-associated factor 2
UBC ubiquitin C
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
VPRBP Vpr (HIV-1) binding protein
XPO1 exportin 1
ZYG11B zyg-11 family member B, cell cycle regulator