| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase|This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class; in addition to an F-box, this protein contains 7 tandem WD40 repeats. This protein binds directly to cyclin E and probably targets cyclin E for ubiquitin-mediated degradation. Mutations in this gene are detected in ovarian and breast cancer cell lines, implicating the gene's potential role in the pathogenesis of human cancers. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012] (NCBI Entrez Gene Database, 55294) |
| External Link | https://ncbi.nlm.nih.gov/gene/55294 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the FBXW7 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.0146475 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 0.0120034 |
| IFRD2 | interferon-related developmental regulator 2 | 0.0119956 |
| E2F2 | E2F transcription factor 2 | 0.011485 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.0112109 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 0.0109045 |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.0106589 |
| UPP1 | uridine phosphorylase 1 | 0.0101591 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.0100754 |
| NVL | nuclear VCP-like | 0.00998882 |
| DUOX2 | dual oxidase 2 | 0.00978536 |
| KRT16 | keratin 16, type I | 0.00945206 |
| LTF | lactotransferrin | 0.00913275 |
| CDA | cytidine deaminase | 0.00912727 |
| S100A9 | S100 calcium binding protein A9 | 0.00905241 |
| GAL | galanin/GMAP prepropeptide | 0.00901292 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 0.00901016 |
| STAT4 | signal transducer and activator of transcription 4 | 0.00892229 |
| KIAA0125 | KIAA0125 | 0.00885166 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00876897 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00852683 |
| FST | follistatin | 0.00852479 |
| REG3A | regenerating islet-derived 3 alpha | 0.00845683 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.00818685 |
| MALL | mal, T-cell differentiation protein-like | 0.00815959 |
| S100A7 | S100 calcium binding protein A7 | 0.00813007 |
| AIM2 | absent in melanoma 2 | 0.00808866 |
| RHOH | ras homolog family member H | 0.0080142 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00794956 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 0.00793586 |
| BUD23 | BUD23 rRNA methyltransferase and ribosome maturation factor | 0.00791387 |
| ETHE1 | ethylmalonic encephalopathy 1 | 0.00785933 |
| RPL36 | ribosomal protein L36 | 0.00785223 |
| PLTP | phospholipid transfer protein | 0.00785126 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00783111 |
| ASS1 | argininosuccinate synthase 1 | 0.00781625 |
| PRPF4 | pre-mRNA processing factor 4 | 0.0077738 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00775274 |
| TPD52 | tumor protein D52 | 0.00767 |
| PWP1 | PWP1 homolog (S. cerevisiae) | 0.00763422 |
| CD320 | CD320 molecule | 0.00759462 |
| PRPS1 | phosphoribosyl pyrophosphate synthetase 1 | 0.00756259 |
| RHCG | Rh family, C glycoprotein | 0.00755146 |
| MZB1 | marginal zone B and B1 cell-specific protein | 0.00754179 |
| RPL14 | ribosomal protein L14 | 0.00751158 |
| SSR4 | signal sequence receptor, delta | 0.00750392 |
| SNRPD2 | small nuclear ribonucleoprotein D2 polypeptide 16.5kDa | 0.00749627 |
| CDC42 | cell division cycle 42 | 0.00748465 |
| DNTT | DNA nucleotidylexotransferase | 0.00743828 |
| CD48 | CD48 molecule | 0.00739423 |
| ERP29 | endoplasmic reticulum protein 29 | 0.00739417 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00736967 |
| CTSZ | cathepsin Z | 0.00736397 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00736307 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.00734423 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00722477 |
| RPS5 | ribosomal protein S5 | 0.00722432 |
| MRPS12 | mitochondrial ribosomal protein S12 | 0.00719117 |
| PLK1 | polo-like kinase 1 | 0.00716535 |
| CD2 | CD2 molecule | 0.00714829 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent | 0.00712581 |
| CD8A | CD8a molecule | 0.00710943 |
| PRMT1 | protein arginine methyltransferase 1 | 0.007079 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | 0.00701518 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00700832 |
| IL32 | interleukin 32 | 0.00699533 |
| ABITRAM | actin binding transcription modulator | 0.00698136 |
| TRAPPC3 | trafficking protein particle complex 3 | 0.00696557 |
| CLCA4 | chloride channel accessory 4 | 0.00696365 |
| TLK2 | tousled-like kinase 2 | 0.00695589 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | 0.00695297 |
| COPE | coatomer protein complex, subunit epsilon | 0.00692649 |
| TCL1A | T-cell leukemia/lymphoma 1A | 0.0069094 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0068337 |
| RPL35 | ribosomal protein L35 | 0.0068328 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00679956 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00678784 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00678384 |
| LCN2 | lipocalin 2 | 0.00674382 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.00669446 |
| MYBPC1 | myosin binding protein C, slow type | 0.00668544 |
| MRPS16 | mitochondrial ribosomal protein S16 | 0.00666775 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | 0.00666643 |
| NKX2-1 | NK2 homeobox 1 | 0.00665658 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | 0.00664674 |
| ATG3 | autophagy related 3 | 0.00663962 |
| TPM4 | tropomyosin 4 | 0.00662333 |
| SPRR1A | small proline-rich protein 1A | 0.00660624 |
| CD19 | CD19 molecule | 0.0065793 |
| REG1B | regenerating islet-derived 1 beta | 0.00657342 |
| NELL2 | NEL-like 2 (chicken) | 0.00657079 |
| PLAU | plasminogen activator, urokinase | 0.00655958 |
| SPRR1B | small proline-rich protein 1B | 0.00655304 |
| RBM34 | RNA binding motif protein 34 | 0.00653153 |
| CYB561 | cytochrome b561 | 0.00651116 |
| PRDX4 | peroxiredoxin 4 | 0.00650396 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.00649959 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00649895 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | 0.0064887 |
| HOXD11 | homeobox D11 | 0.00645948 |
| MDFIC | MyoD family inhibitor domain containing | 0.00645805 |
| FOSL1 | FOS-like antigen 1 | 0.0064506 |
| CLDN4 | claudin 4 | 0.0064429 |
| FPGS | folylpolyglutamate synthase | 0.00643329 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.00638736 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.00638241 |
| CCDC85B | coiled-coil domain containing 85B | 0.00635988 |
| MCOLN1 | mucolipin 1 | 0.00635 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00633806 |
| DSG3 | desmoglein 3 | 0.00630015 |
| FASTKD1 | FAST kinase domains 1 | 0.00629247 |
| REG1A | regenerating islet-derived 1 alpha | 0.00628655 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein | 0.00626676 |
| MAL | mal, T-cell differentiation protein | 0.00625269 |
| USP18 | ubiquitin specific peptidase 18 | 0.006252 |
| ECM1 | extracellular matrix protein 1 | 0.00622522 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.00620761 |
| PIGR | polymeric immunoglobulin receptor | 0.00618671 |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) | 0.00618025 |
| PPA1 | pyrophosphatase (inorganic) 1 | 0.00617683 |
| SNRNP40 | small nuclear ribonucleoprotein 40kDa (U5) | 0.00614169 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | 0.00613091 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase | 0.00610659 |
| HMG20B | high mobility group 20B | 0.00610626 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.00607297 |
| TFF1 | trefoil factor 1 | 0.0060661 |
| RPL29 | ribosomal protein L29 | 0.00605026 |
| ZNF430 | zinc finger protein 430 | 0.00604735 |
| GNLY | granulysin | 0.0060131 |
| AOC1 | amine oxidase, copper containing 1 | 0.00600273 |
| EPHB4 | EPH receptor B4 | 0.00600101 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00599071 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00597599 |
| RCAN1 | regulator of calcineurin 1 | 0.00595775 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00593143 |
| TXNIP | thioredoxin interacting protein | 0.0059248 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00589061 |
| RIOK3 | RIO kinase 3 | 0.00589022 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | 0.00588745 |
| TMEM38B | transmembrane protein 38B | 0.00587638 |
| AK1 | adenylate kinase 1 | 0.00586335 |
| SMAGP | small cell adhesion glycoprotein | 0.00586146 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00583241 |
| FCMR | Fc fragment of IgM receptor | 0.00583104 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | 0.00582449 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A | 0.00581366 |
| ZNHIT1 | zinc finger, HIT-type containing 1 | 0.00579501 |
| ATP5F1D | ATP synthase F1 subunit delta | 0.00576715 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) | 0.0057641 |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.00575054 |
| MMP10 | matrix metallopeptidase 10 | 0.00574331 |
| IFT57 | intraflagellar transport 57 | 0.0057411 |
| LYPD3 | LY6/PLAUR domain containing 3 | 0.00573188 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | 0.00572144 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 0.00569812 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00569508 |
| ACTC1 | actin, alpha, cardiac muscle 1 | 0.0056926 |
| MMP3 | matrix metallopeptidase 3 | 0.00568557 |
| HOXD10 | homeobox D10 | 0.00567039 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00566212 |
| POLR2J | polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa | 0.00565974 |
| NEFH | neurofilament, heavy polypeptide | 0.00563052 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00562597 |
| INHBA | inhibin, beta A | 0.00561812 |
| SLC35F2 | solute carrier family 35, member F2 | 0.0056166 |
| MME | membrane metallo-endopeptidase | 0.00561511 |
| DNASE2 | deoxyribonuclease II, lysosomal | 0.00560876 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 | 0.00560317 |
| THEMIS2 | thymocyte selection associated family member 2 | 0.00560084 |
| QRSL1 | glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 | 0.00559029 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0055807 |
| EIF3I | eukaryotic translation initiation factor 3, subunit I | 0.00557926 |
| KRT14 | keratin 14, type I | 0.005577 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | 0.00557117 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | 0.00555854 |
| PRPF19 | pre-mRNA processing factor 19 | 0.00553434 |
| LPIN1 | lipin 1 | 0.00552596 |
| TAGLN2 | transgelin 2 | 0.0055005 |
| DES | desmin | 0.00548756 |
| EVI2A | ecotropic viral integration site 2A | 0.00548374 |
| BLVRB | biliverdin reductase B | 0.00547908 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.00547725 |
| S100A8 | S100 calcium binding protein A8 | 0.00547544 |
| RTN2 | reticulon 2 | 0.00547141 |
| UFM1 | ubiquitin-fold modifier 1 | 0.00546552 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 | 0.00545915 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | 0.00544505 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00544354 |
| PDAP1 | PDGFA associated protein 1 | 0.0054408 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00543693 |
| C1QBP | complement component 1, q subcomponent binding protein | 0.00543533 |
| IL15 | interleukin 15 | 0.00543482 |
| AHCY | adenosylhomocysteinase | 0.00542929 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.00541741 |
| CTSK | cathepsin K | 0.00540488 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | 0.00540221 |
| RBM38 | RNA binding motif protein 38 | 0.00539723 |
| XIC | X chromosome inactivation center | 0.0053965 |
| IVL | involucrin | 0.00539517 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00537429 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.00537404 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00537364 |
| ODAM | odontogenic, ameloblast asssociated | 0.00536576 |
| TRAPPC6A | trafficking protein particle complex 6A | 0.00535368 |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) | 0.00535276 |
| RAB5C | RAB5C, member RAS oncogene family | 0.00534919 |
| BLNK | B-cell linker | 0.00534503 |
| MED6 | mediator complex subunit 6 | 0.00534078 |
| KLF6 | Kruppel-like factor 6 | 0.00533183 |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 | 0.00532747 |
| CRYAB | crystallin, alpha B | 0.00531748 |
| CD177 | CD177 molecule | 0.00531606 |
| BAG2 | BCL2-associated athanogene 2 | 0.00530803 |
| APH1A | APH1A gamma secretase subunit | 0.00530582 |
| SRM | spermidine synthase | 0.00530142 |
| IL7R | interleukin 7 receptor | 0.0053009 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.00528599 |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | 0.00526085 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | 0.00525934 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase | 0.00525059 |
| VPREB1 | pre-B lymphocyte 1 | 0.00524511 |
| ACTB | actin, beta | 0.00524275 |
| ATG5 | autophagy related 5 | 0.00523021 |
| ZNF593 | zinc finger protein 593 | 0.00522902 |
| L1TD1 | LINE-1 type transposase domain containing 1 | 0.00522609 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.0052213 |
| SIDT1 | SID1 transmembrane family, member 1 | 0.00521983 |
| COMP | cartilage oligomeric matrix protein | 0.00521848 |
| TRIP6 | thyroid hormone receptor interactor 6 | 0.00521473 |
| GSTZ1 | glutathione S-transferase zeta 1 | 0.0052079 |
| MFAP2 | microfibrillar-associated protein 2 | 0.00520617 |
| TARP | TCR gamma alternate reading frame protein | 0.00520082 |
| CD38 | CD38 molecule | 0.00519629 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00518844 |
| PHF11 | PHD finger protein 11 | 0.00518723 |
| ZNF586 | zinc finger protein 586 | 0.00517718 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0051653 |
| ASF1B | anti-silencing function 1B histone chaperone | 0.00516383 |
| PLEK2 | pleckstrin 2 | 0.00516314 |
| COMMD3 | COMM domain containing 3 | 0.00516232 |
| INA | internexin neuronal intermediate filament protein, alpha | 0.00516174 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 0.00515898 |
| RNASEH2A | ribonuclease H2, subunit A | 0.00515507 |
| PTK7 | protein tyrosine kinase 7 (inactive) | 0.00515119 |
| HOXB13 | homeobox B13 | 0.00514926 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.00514897 |
| PYCARD | PYD and CARD domain containing | 0.00514875 |
| ATF3 | activating transcription factor 3 | 0.00514872 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.00514181 |
| NOC3L | nucleolar complex associated 3 homolog (S. cerevisiae) | 0.00513789 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -0.0183014 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.016695 |
| FGG | fibrinogen gamma chain | -0.0145997 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.0143777 |
| IL1R1 | interleukin 1 receptor, type I | -0.0139242 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0139191 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0129877 |
| COL3A1 | collagen, type III, alpha 1 | -0.0129058 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.0125989 |
| FRY | furry homolog (Drosophila) | -0.0125441 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0123841 |
| KRT23 | keratin 23, type I | -0.011981 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.0118978 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | -0.0116919 |
| BEX1 | brain expressed, X-linked 1 | -0.0116679 |
| PEG3 | paternally expressed 3 | -0.0116075 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.011475 |
| CFB | complement factor B | -0.0113976 |
| MGLL | monoglyceride lipase | -0.0109785 |
| SYBU | syntabulin (syntaxin-interacting) | -0.0109568 |
| LRRC17 | leucine rich repeat containing 17 | -0.0108802 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.010849 |
| A2M | alpha-2-macroglobulin | -0.0108286 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0107758 |
| GPC3 | glypican 3 | -0.0106896 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.0106295 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | -0.0105303 |
| COL1A2 | collagen, type I, alpha 2 | -0.0104697 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0104095 |
| NCALD | neurocalcin delta | -0.0103795 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0103743 |
| AGTR1 | angiotensin II receptor, type 1 | -0.0103548 |
| MSLN | mesothelin | -0.0103232 |
| MEIS2 | Meis homeobox 2 | -0.0102968 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0102313 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.0102053 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.0102011 |
| HAL | histidine ammonia-lyase | -0.0100772 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0100083 |
| PLAT | plasminogen activator, tissue | -0.00989758 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.00988587 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.00982325 |
| CPE | carboxypeptidase E | -0.00978331 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00969231 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00965678 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00961896 |
| PLSCR4 | phospholipid scramblase 4 | -0.00961681 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00961054 |
| KRT19 | keratin 19, type I | -0.00957705 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00956471 |
| TNS3 | tensin 3 | -0.0095606 |
| PDZD2 | PDZ domain containing 2 | -0.00956054 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | -0.00954731 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | -0.00954447 |
| SOBP | sine oculis binding protein homolog (Drosophila) | -0.00947128 |
| CP | ceruloplasmin (ferroxidase) | -0.00943279 |
| MANSC1 | MANSC domain containing 1 | -0.00942048 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00937594 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.00936904 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0093644 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00935051 |
| ITM2A | integral membrane protein 2A | -0.00933866 |
| C7 | complement component 7 | -0.00929611 |
| NID1 | nidogen 1 | -0.00922587 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | -0.00922191 |
| FGA | fibrinogen alpha chain | -0.0091779 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0091607 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00906093 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00906065 |
| MEIS1 | Meis homeobox 1 | -0.00903537 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.00896683 |
| PDGFD | platelet derived growth factor D | -0.00895805 |
| ZBTB16 | zinc finger and BTB domain containing 16 | -0.00894492 |
| FGB | fibrinogen beta chain | -0.00884127 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00883022 |
| CFH | complement factor H | -0.00882215 |
| MATN2 | matrilin 2 | -0.00882213 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -0.00879251 |
| MLPH | melanophilin | -0.00870697 |
| FN1 | fibronectin 1 | -0.00862202 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00858697 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.00857119 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00856322 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | -0.008559 |
| ADAMTSL3 | ADAMTS-like 3 | -0.00855301 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00854631 |
| NOTCH2 | notch 2 | -0.00852127 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -0.00851226 |
| MYOF | myoferlin | -0.0085059 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.00849607 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00846673 |
| NCOA1 | nuclear receptor coactivator 1 | -0.00846171 |
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 | -0.00844685 |
| PDGFC | platelet derived growth factor C | -0.00844421 |
| C3 | complement component 3 | -0.00843715 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00838997 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.00833721 |
| SCARB2 | scavenger receptor class B, member 2 | -0.00830008 |
| NCOA3 | nuclear receptor coactivator 3 | -0.00829227 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.00823815 |
| CADM1 | cell adhesion molecule 1 | -0.00822645 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00821428 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00821411 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.00821129 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.00820988 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00819445 |
| PCDH17 | protocadherin 17 | -0.00815802 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.0081467 |
| SERPINA6 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 | -0.008109 |
| TSPAN7 | tetraspanin 7 | -0.00808233 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00805728 |
| PON2 | paraoxonase 2 | -0.0080248 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.008023 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.00797062 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | -0.00789511 |
| KIF16B | kinesin family member 16B | -0.00789492 |
| PDZK1 | PDZ domain containing 1 | -0.0078715 |
| APOA2 | apolipoprotein A-II | -0.00786419 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | -0.00785395 |
| APOB | apolipoprotein B | -0.00785012 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00784115 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00780325 |
| SNX7 | sorting nexin 7 | -0.00778772 |
| TFRC | transferrin receptor | -0.00777114 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00776664 |
| EMP2 | epithelial membrane protein 2 | -0.00774272 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00773138 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.00773117 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00772418 |
| CFI | complement factor I | -0.0077074 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00768723 |
| JAG1 | jagged 1 | -0.00767989 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.00767603 |
| OXTR | oxytocin receptor | -0.00767182 |
| ARG1 | arginase 1 | -0.00766613 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.00763278 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00761885 |
| ABLIM1 | actin binding LIM protein 1 | -0.00761009 |
| CPD | carboxypeptidase D | -0.00758467 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.00758249 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.00757928 |
| ATXN1 | ataxin 1 | -0.00756765 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.00755664 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.00751991 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.00751925 |
| CLU | clusterin | -0.00747596 |
| ALB | albumin | -0.00747245 |
| CTSA | cathepsin A | -0.00745272 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | -0.00744606 |
| TOX | thymocyte selection-associated high mobility group box | -0.00741316 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0074067 |
| RGS5 | regulator of G-protein signaling 5 | -0.00739773 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00736806 |
| LDB2 | LIM domain binding 2 | -0.00735125 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00732898 |
| EPCAM | epithelial cell adhesion molecule | -0.00732633 |
| TPBG | trophoblast glycoprotein | -0.00730898 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.00729416 |
| GSTA1 | glutathione S-transferase alpha 1 | -0.00725324 |
| THBD | thrombomodulin | -0.0072526 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.00725034 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00724254 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00723897 |
| MUC16 | mucin 16, cell surface associated | -0.00721866 |
| CRP | C-reactive protein, pentraxin-related | -0.00721384 |
| CLEC3B | C-type lectin domain family 3, member B | -0.00720084 |
| BICC1 | BicC family RNA binding protein 1 | -0.0071787 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.00717775 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -0.0071763 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.0071705 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00715973 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.00715836 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00715619 |
| ADIRF | adipogenesis regulatory factor | -0.00714377 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00710601 |
| RELN | reelin | -0.00709645 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00705601 |
| TOX3 | TOX high mobility group box family member 3 | -0.00702261 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | -0.00700716 |
| RAI2 | retinoic acid induced 2 | -0.00699966 |
| SLC16A4 | solute carrier family 16, member 4 | -0.00698368 |
| ZNF512B | zinc finger protein 512B | -0.00697974 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00697574 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.00697127 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00697048 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00696994 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.00694605 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.00689584 |
| CES1 | carboxylesterase 1 | -0.00689149 |
| AHSG | alpha-2-HS-glycoprotein | -0.00687415 |
| QKI | QKI, KH domain containing, RNA binding | -0.00685309 |
| TLE4 | transducin-like enhancer of split 4 | -0.00684647 |
| COBL | cordon-bleu WH2 repeat protein | -0.00684606 |
| FAM198B | family with sequence similarity 198, member B | -0.00684478 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | -0.00684465 |
| PMP22 | peripheral myelin protein 22 | -0.00683639 |
| GUCY2C | guanylate cyclase 2C | -0.00682463 |
| C14ORF132 | chromosome 14 open reading frame 132 | -0.00682032 |
| AGR2 | anterior gradient 2 | -0.00681057 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.00679999 |
| SOSTDC1 | sclerostin domain containing 1 | -0.00679065 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | -0.00678476 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.00678079 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.00677549 |
| TMEM100 | transmembrane protein 100 | -0.0067754 |
| CLIC5 | chloride intracellular channel 5 | -0.00676526 |
| PLA1A | phospholipase A1 member A | -0.00676164 |
| PANK2 | pantothenate kinase 2 | -0.00675008 |
| DCN | decorin | -0.00673519 |
| ABHD2 | abhydrolase domain containing 2 | -0.00672822 |
| WFS1 | Wolfram syndrome 1 (wolframin) | -0.00672524 |
| STK10 | serine/threonine kinase 10 | -0.00672269 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.00672 |
| WLS | wntless Wnt ligand secretion mediator | -0.00670585 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00669178 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.00667469 |
| METTL7A | methyltransferase like 7A | -0.00666965 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0066613 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -0.00663942 |
| MGP | matrix Gla protein | -0.00663707 |
| SRGN | serglycin | -0.00663296 |
| C4BPA | complement component 4 binding protein, alpha | -0.00660812 |
| ADD3 | adducin 3 (gamma) | -0.00660391 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.00660316 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0066013 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00659449 |
| PROM1 | prominin 1 | -0.00656876 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.00656091 |
| ABAT | 4-aminobutyrate aminotransferase | -0.00655553 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00655204 |
| ORM1 | orosomucoid 1 | -0.00653223 |
| CHN2 | chimerin 2 | -0.0065306 |
| NOTCH2NL | notch 2 N-terminal like | -0.00653042 |
| TRIM22 | tripartite motif containing 22 | -0.0065217 |
| LYZ | lysozyme | -0.0065216 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.00651243 |
| APOA1 | apolipoprotein A-I | -0.00650027 |
| FILIP1L | filamin A interacting protein 1-like | -0.00646502 |
| OGN | osteoglycin | -0.00646484 |
| GFRA1 | GDNF family receptor alpha 1 | -0.00645683 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00645417 |
| TYRP1 | tyrosinase-related protein 1 | -0.00645216 |
| IL20RA | interleukin 20 receptor, alpha | -0.00645054 |
| VCAN | versican | -0.00645014 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.00644167 |
| BCL6 | B-cell CLL/lymphoma 6 | -0.00643997 |
| FGL1 | fibrinogen-like 1 | -0.00643177 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.00643156 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.00642713 |
| TMEM131 | transmembrane protein 131 | -0.00642712 |
