FCERI mediated MAPK activation Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-2871796
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Genes

36 proteins participating in the FCERI mediated MAPK activation pathway from the Reactome Pathways 2024 dataset.

Symbol Name
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FOS FBJ murine osteosarcoma viral oncogene homolog
GRAP2 GRB2-related adaptor protein 2
GRB2 growth factor receptor-bound protein 2
HRAS Harvey rat sarcoma viral oncogene homolog
IGH immunoglobulin heavy locus
IGL immunoglobulin lambda locus
IGLL5 immunoglobulin lambda-like polypeptide 5
JUN jun proto-oncogene
KRAS Kirsten rat sarcoma viral oncogene homolog
LAT linker for activation of T cells
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SOS1 son of sevenless homolog 1 (Drosophila)
SYK spleen tyrosine kinase
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor