FCGR3A Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description Fc fragment of IgG, low affinity IIIa, receptor (CD16a)|This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2214)
External Link https://ncbi.nlm.nih.gov/gene/2214
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Genes

499 genes differentially expressed following the FCGR3A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
TSPAN8 tetraspanin 8 0.018871
LGALS4 lectin, galactoside-binding, soluble, 4 0.0141045
S100P S100 calcium binding protein P 0.0138255
SRPX sushi-repeat containing protein, X-linked 0.013072
PCNA proliferating cell nuclear antigen 0.012478
AGR2 anterior gradient 2 0.012424
TUBB2A tubulin, beta 2A class IIa 0.0122926
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.0105469
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0103202
PEG3 paternally expressed 3 0.0103072
CXCL3 chemokine (C-X-C motif) ligand 3 0.0102647
TFF1 trefoil factor 1 0.0100864
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00970394
TOX3 TOX high mobility group box family member 3 0.00961758
MYRF myelin regulatory factor 0.00958159
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.00944472
TUBB2B tubulin, beta 2B class IIb 0.0091945
HSPA2 heat shock 70kDa protein 2 0.00918357
ENOPH1 enolase-phosphatase 1 0.00915128
KLF6 Kruppel-like factor 6 0.00911803
CDH17 cadherin 17, LI cadherin (liver-intestine) 0.00904162
CANT1 calcium activated nucleotidase 1 0.00898518
AOC1 amine oxidase, copper containing 1 0.00888376
BEX1 brain expressed, X-linked 1 0.00885848
GPX2 glutathione peroxidase 2 0.00885836
PLP1 proteolipid protein 1 0.00867661
GPM6B glycoprotein M6B 0.00858943
NRCAM neuronal cell adhesion molecule 0.00850564
HEPH hephaestin 0.00845384
TM4SF4 transmembrane 4 L six family member 4 0.00840529
TMC5 transmembrane channel-like 5 0.00835416
MEN1 multiple endocrine neoplasia I 0.00832807
S100B S100 calcium binding protein B 0.00831748
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00820963
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00812745
GCH1 GTP cyclohydrolase 1 0.00808689
PRSS3 protease, serine, 3 0.00806295
EPS8L3 EPS8-like 3 0.00799449
INSM1 insulinoma-associated 1 0.00797427
JAM3 junctional adhesion molecule 3 0.00791875
AKAP12 A kinase (PRKA) anchor protein 12 0.00790797
HOXB6 homeobox B6 0.00780174
BLNK B-cell linker 0.00771756
PWP1 PWP1 homolog (S. cerevisiae) 0.00768841
CXCL8 chemokine (C-X-C motif) ligand 8 0.00763914
CIB2 calcium and integrin binding family member 2 0.00762372
MAB21L2 mab-21-like 2 (C. elegans) 0.00755739
GMDS GDP-mannose 4,6-dehydratase 0.00754912
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00746621
BAMBI BMP and activin membrane-bound inhibitor 0.00746288
PLS1 plastin 1 0.00735901
FA2H fatty acid 2-hydroxylase 0.00730219
PMP2 peripheral myelin protein 2 0.00728859
SOX9 SRY (sex determining region Y)-box 9 0.00726465
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00717911
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00713572
MVP major vault protein 0.00703456
DCT dopachrome tautomerase 0.00699017
MUC13 mucin 13, cell surface associated 0.00695939
IRF1 interferon regulatory factor 1 0.00687503
RNH1 ribonuclease/angiogenin inhibitor 1 0.0068676
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00686518
COL9A3 collagen, type IX, alpha 3 0.0068472
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.00681332
BCL2A1 BCL2-related protein A1 0.00679268
CDC42 cell division cycle 42 0.00678355
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.0066628
SCRG1 stimulator of chondrogenesis 1 0.0066369
SPARCL1 SPARC-like 1 (hevin) 0.00663498
ECI2 enoyl-CoA delta isomerase 2 0.00659296
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.00653567
AREG amphiregulin 0.00648982
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.0064784
KIFAP3 kinesin-associated protein 3 0.00647198
MUC2 mucin 2, oligomeric mucus/gel-forming 0.00646426
MLPH melanophilin 0.00641648
TFF2 trefoil factor 2 0.00640826
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00636917
COG2 component of oligomeric golgi complex 2 0.00634663
F3 coagulation factor III (thromboplastin, tissue factor) 0.00632197
TEX10 testis expressed 10 0.00629091
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 0.00628687
ETFB electron-transfer-flavoprotein, beta polypeptide 0.00626939
PALLD palladin, cytoskeletal associated protein 0.00625149
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00624486
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 0.00624259
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00622502
DCHS1 dachsous cadherin-related 1 0.00620023
WLS wntless Wnt ligand secretion mediator 0.00619499
LEF1 lymphoid enhancer-binding factor 1 0.00618387
C21ORF91 chromosome 21 open reading frame 91 0.00617797
RAB8B RAB8B, member RAS oncogene family 0.00616841
ATOX1 antioxidant 1 copper chaperone 0.00613092
MRPS16 mitochondrial ribosomal protein S16 0.00613085
TP53I3 tumor protein p53 inducible protein 3 0.00611624
ICAM2 intercellular adhesion molecule 2 0.00611097
HOXB7 homeobox B7 0.00610379
IER5 immediate early response 5 0.00610021
AZIN1 antizyme inhibitor 1 0.00609387
SMTN smoothelin 0.00605973
ZNF91 zinc finger protein 91 0.00605939
RIOX2 ribosomal oxygenase 2 0.00604537
CXCL5 chemokine (C-X-C motif) ligand 5 0.00603153
TDP2 tyrosyl-DNA phosphodiesterase 2 0.00602979
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00602956
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00602833
TMEM176A transmembrane protein 176A 0.00602744
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00600559
CLCA1 chloride channel accessory 1 0.00600173
KIAA0226L KIAA0226-like 0.00598915
EPCAM epithelial cell adhesion molecule 0.00597233
DSTN destrin (actin depolymerizing factor) 0.00594681
VDAC2 voltage-dependent anion channel 2 0.00593444
FCGBP Fc fragment of IgG binding protein 0.00593417
CNTN1 contactin 1 0.00592796
CRIP1 cysteine-rich protein 1 (intestinal) 0.00588334
ALDOB aldolase B, fructose-bisphosphate 0.00587967
IQGAP2 IQ motif containing GTPase activating protein 2 0.00586465
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00584904
MTUS1 microtubule associated tumor suppressor 1 0.00583634
MATN2 matrilin 2 0.00583537
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 0.00582831
KRT20 keratin 20, type I 0.00581131
MAGEA3 melanoma antigen family A3 0.00580195
MTMR11 myotubularin related protein 11 0.00579263
RGS1 regulator of G-protein signaling 1 0.00579052
FTH1 ferritin, heavy polypeptide 1 0.00577708
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00577289
BIRC3 baculoviral IAP repeat containing 3 0.00575342
NEBL nebulette 0.00573321
STK10 serine/threonine kinase 10 0.00572227
PRPH peripherin 0.00571658
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 0.00570836
LCK LCK proto-oncogene, Src family tyrosine kinase 0.00570802
SNAI2 snail family zinc finger 2 0.00570453
TMEM176B transmembrane protein 176B 0.00570345
FOXD1 forkhead box D1 0.0056811
KLHL24 kelch-like family member 24 0.00568004
ATF3 activating transcription factor 3 0.00567486
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 0.0056466
TOM1L1 target of myb1 (chicken)-like 1 0.00562163
LRRN3 leucine rich repeat neuronal 3 0.00562096
ITPK1 inositol-tetrakisphosphate 1-kinase 0.00560126
LAMA4 laminin, alpha 4 0.00559201
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.00558654
ISG20 interferon stimulated exonuclease gene 20kDa 0.0055849
MGST3 microsomal glutathione S-transferase 3 0.00558238
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.00557413
TMEM230 transmembrane protein 230 0.0055524
BCAS1 breast carcinoma amplified sequence 1 0.00554508
CDO1 cysteine dioxygenase type 1 0.00554392
SCD5 stearoyl-CoA desaturase 5 0.00552964
CHGB chromogranin B 0.0055216
DAAM1 dishevelled associated activator of morphogenesis 1 0.00552011
GPR137B G protein-coupled receptor 137B 0.00551724
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.00551723
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.00551583
DDIT3 DNA-damage-inducible transcript 3 0.00550522
STX7 syntaxin 7 0.00550229
AP5M1 adaptor-related protein complex 5, mu 1 subunit 0.00549083
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.00547917
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 0.0054696
RGS2 regulator of G-protein signaling 2 0.00546244
VIL1 villin 1 0.00544107
C14ORF132 chromosome 14 open reading frame 132 0.00543648
ANXA6 annexin A6 0.00543019
IVNS1ABP influenza virus NS1A binding protein 0.00539136
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00538211
CHGA chromogranin A 0.00537606
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00537381
HILPDA hypoxia inducible lipid droplet-associated 0.00537234
FERMT1 fermitin family member 1 0.005363
CXCL2 chemokine (C-X-C motif) ligand 2 0.0053446
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00533566
XIC X chromosome inactivation center 0.00533549
COLEC12 collectin sub-family member 12 0.00533215
MEP1A meprin A, alpha (PABA peptide hydrolase) 0.00532544
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.00532265
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00532037
EDN1 endothelin 1 0.00531997
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.00531757
ANXA2P2 annexin A2 pseudogene 2 0.00531498
NAMPT nicotinamide phosphoribosyltransferase 0.0052995
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 0.00529781
ITGB4 integrin, beta 4 0.00529465
TMEM14A transmembrane protein 14A 0.00529406
TSPAN1 tetraspanin 1 0.00528262
TCEAL2 transcription elongation factor A (SII)-like 2 0.00528069
FGFR4 fibroblast growth factor receptor 4 0.00527473
LPXN leupaxin 0.00527042
RRAGD Ras-related GTP binding D 0.0052667
TSPAN15 tetraspanin 15 0.00526377
SELE selectin E 0.00526313
ANXA3 annexin A3 0.0052606
ARHGAP15 Rho GTPase activating protein 15 0.00525355
CAPN9 calpain 9 0.00525267
KLF4 Kruppel-like factor 4 (gut) 0.00525163
NAP1L3 nucleosome assembly protein 1-like 3 0.00523669
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.00523317
NXT1 nuclear transport factor 2-like export factor 1 0.00522337
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 0.00520963
AK4 adenylate kinase 4 0.0052058
BAALC brain and acute leukemia, cytoplasmic 0.00520412
BTG1 B-cell translocation gene 1, anti-proliferative 0.00519897
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.00518712
CORO1A coronin, actin binding protein, 1A 0.0051821
CCL20 chemokine (C-C motif) ligand 20 0.005177
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00517501
CD14 CD14 molecule 0.00516339
PDZD2 PDZ domain containing 2 0.00515842
JAM2 junctional adhesion molecule 2 0.00515445
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.00514327
CD83 CD83 molecule 0.00514195
WSB1 WD repeat and SOCS box containing 1 0.00511705
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.00511128
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.00506688
CD58 CD58 molecule 0.00505522
KRT19 keratin 19, type I 0.00505058
IRF8 interferon regulatory factor 8 0.00504974
TBX2 T-box 2 0.00504889
AEBP1 AE binding protein 1 0.00504637
TYR tyrosinase 0.00504116
SMC1A structural maintenance of chromosomes 1A 0.0050387
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.00503798
FXYD6 FXYD domain containing ion transport regulator 6 0.0050345
ZSCAN18 zinc finger and SCAN domain containing 18 0.00502348
REEP1 receptor accessory protein 1 0.00501671
GADD45B growth arrest and DNA-damage-inducible, beta 0.00501595
NID2 nidogen 2 (osteonidogen) 0.00501439
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 0.0050132
ZNF277 zinc finger protein 277 0.0049973
PAGE4 P antigen family, member 4 (prostate associated) 0.00499242
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 0.0049856
GSTO1 glutathione S-transferase omega 1 0.0049826
LAMB1 laminin, beta 1 0.00498058
FAM117A family with sequence similarity 117, member A 0.00497656
CLIP2 CAP-GLY domain containing linker protein 2 0.0049478
AHI1 Abelson helper integration site 1 0.00493146
CDC45 cell division cycle 45 0.00491491
REG1A regenerating islet-derived 1 alpha 0.00489176
BTG3 BTG family, member 3 0.00488587
RXYLT1 ribitol xylosyltransferase 1 0.00485832
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00485477
PSEN1 presenilin 1 0.00484984
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.00483988
MKKS McKusick-Kaufman syndrome 0.00483654
NELFE negative elongation factor complex member E 0.00482798
TKTL1 transketolase-like 1 0.00482659
PLLP plasmolipin 0.00482551

decreased expression

Symbol Name Standardized Value
CXCL14 chemokine (C-X-C motif) ligand 14 -0.0183498
AQP3 aquaporin 3 (Gill blood group) -0.0137915
NIBAN1 niban apoptosis regulator 1 -0.0127103
KRT15 keratin 15, type I -0.0126709
IFITM1 interferon induced transmembrane protein 1 -0.0122902
S100A8 S100 calcium binding protein A8 -0.0110316
CRABP2 cellular retinoic acid binding protein 2 -0.0109094
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.0107662
TACSTD2 tumor-associated calcium signal transducer 2 -0.0106569
TXNDC9 thioredoxin domain containing 9 -0.0104381
LAPTM4B lysosomal protein transmembrane 4 beta -0.0103748
LY6E lymphocyte antigen 6 complex, locus E -0.0100361
FOLR1 folate receptor 1 (adult) -0.0100263
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00987824
PXDN peroxidasin -0.00980832
KRT5 keratin 5, type II -0.00969665
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.0096041
SIRT3 sirtuin 3 -0.00956897
RTN2 reticulon 2 -0.00915626
NELL2 NEL-like 2 (chicken) -0.00861887
DPYD dihydropyrimidine dehydrogenase -0.00861081
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 -0.00861016
MT1E metallothionein 1E -0.008574
KRT13 keratin 13, type I -0.0085568
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -0.00850971
KRT14 keratin 14, type I -0.00850342
OLFM1 olfactomedin 1 -0.00840424
XPO7 exportin 7 -0.00839442
MMP7 matrix metallopeptidase 7 -0.00834147
LY96 lymphocyte antigen 96 -0.00829346
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00826898
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00817094
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -0.00813994
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00809867
KRT17 keratin 17, type I -0.00794571
OBSL1 obscurin-like 1 -0.0078944
SPRR1B small proline-rich protein 1B -0.00789076
NUSAP1 nucleolar and spindle associated protein 1 -0.00777541
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -0.00774961
SGK1 serum/glucocorticoid regulated kinase 1 -0.00774372
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 -0.00773431
CIT citron rho-interacting serine/threonine kinase -0.00770775
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -0.00766404
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00763737
TPBG trophoblast glycoprotein -0.00763384
JCHAIN joining chain of multimeric IgA and IgM -0.00760876
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00756991
ESR1 estrogen receptor 1 -0.00750859
ANPEP alanyl (membrane) aminopeptidase -0.00750431
KRT23 keratin 23, type I -0.00748524
MB myoglobin -0.00747874
NFIB nuclear factor I/B -0.00723929
KRT6A keratin 6A, type II -0.00722739
BST2 bone marrow stromal cell antigen 2 -0.00722
BAG3 BCL2-associated athanogene 3 -0.00720748
NMU neuromedin U -0.00719351
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00715746
SPRR3 small proline-rich protein 3 -0.00713966
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 -0.0071282
PDZK1IP1 PDZK1 interacting protein 1 -0.00711937
IFITM2 interferon induced transmembrane protein 2 -0.00711853
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 -0.00710381
TRPS1 trichorhinophalangeal syndrome I -0.00704058
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00703988
ENO3 enolase 3 (beta, muscle) -0.00701074
TNNT1 troponin T type 1 (skeletal, slow) -0.0069498
METTL7A methyltransferase like 7A -0.00694236
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -0.00683213
CD302 CD302 molecule -0.00683102
HMGB3 high mobility group box 3 -0.00679909
CBS cystathionine-beta-synthase -0.00679296
MDFIC MyoD family inhibitor domain containing -0.00678042
HAT1 histone acetyltransferase 1 -0.00677027
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 -0.00672968
SFTPB surfactant protein B -0.00666343
NKX2-1 NK2 homeobox 1 -0.00666265
IFITM3 interferon induced transmembrane protein 3 -0.00663972
RFC5 replication factor C (activator 1) 5, 36.5kDa -0.00659241
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 -0.00659021
PRKCI protein kinase C, iota -0.00655425
AGRN agrin -0.00654535
MET MET proto-oncogene, receptor tyrosine kinase -0.00652211
ALCAM activated leukocyte cell adhesion molecule -0.00650012
GNAS GNAS complex locus -0.00648987
HMGN3 high mobility group nucleosomal binding domain 3 -0.00648783
MCFD2 multiple coagulation factor deficiency 2 -0.00647113
DHCR24 24-dehydrocholesterol reductase -0.00645987
TTN titin -0.00642838
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00641718
RBM38 RNA binding motif protein 38 -0.00639194
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 -0.00639152
HLA-C major histocompatibility complex, class I, C -0.006365
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 -0.00628874
TAL1 T-cell acute lymphocytic leukemia 1 -0.00622838
RNPS1 RNA binding protein S1, serine-rich domain -0.00620789
WWC3 WWC family member 3 -0.00615987
NFE2L2 nuclear factor, erythroid 2-like 2 -0.00615633
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.00615563
AQP1 aquaporin 1 (Colton blood group) -0.00611864
PPL periplakin -0.00611787
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) -0.00609954
KDM5D lysine (K)-specific demethylase 5D -0.00608091
LMO3 LIM domain only 3 (rhombotin-like 2) -0.00607326
WNT5A wingless-type MMTV integration site family, member 5A -0.00605692
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -0.00604954
CFB complement factor B -0.00604733
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 -0.00604647
NOTCH2 notch 2 -0.00604414
RERE arginine-glutamic acid dipeptide (RE) repeats -0.00604354
STEAP3 STEAP family member 3, metalloreductase -0.00602288
KRT6B keratin 6B, type II -0.00601486
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00601219
NRGN neurogranin (protein kinase C substrate, RC3) -0.00600158
RYR1 ryanodine receptor 1 (skeletal) -0.00599882
ACTA1 actin, alpha 1, skeletal muscle -0.00598483
ZNF512B zinc finger protein 512B -0.00598359
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase -0.00596509
RPIA ribose 5-phosphate isomerase A -0.00596433
CYRIA CYFIP related Rac1 interactor A -0.0059327
ISG15 ISG15 ubiquitin-like modifier -0.00592644
LRP2 low density lipoprotein receptor-related protein 2 -0.00592217
ALOX5 arachidonate 5-lipoxygenase -0.00591846
FAM234B family with sequence similarity 234 member B -0.00591259
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00589315
PDE2A phosphodiesterase 2A, cGMP-stimulated -0.00584928
P3H2 prolyl 3-hydroxylase 2 -0.00583235
AKAP8 A kinase (PRKA) anchor protein 8 -0.00576434
SUB1 SUB1 homolog (S. cerevisiae) -0.00575808
CCNC cyclin C -0.00575174
NPY1R neuropeptide Y receptor Y1 -0.00574884
YBX3 Y box binding protein 3 -0.00573398
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -0.00572876
KPNA6 karyopherin alpha 6 (importin alpha 7) -0.00570475
COBLL1 cordon-bleu WH2 repeat protein-like 1 -0.0056911
MYL2 myosin, light chain 2, regulatory, cardiac, slow -0.00566941
SIK1 salt-inducible kinase 1 -0.00565389
ADCY9 adenylate cyclase 9 -0.00562819
CCL2 chemokine (C-C motif) ligand 2 -0.00562199
ADARB1 adenosine deaminase, RNA-specific, B1 -0.00562184
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain -0.00561797
GNG10 guanine nucleotide binding protein (G protein), gamma 10 -0.00560977
SLCO3A1 solute carrier organic anion transporter family, member 3A1 -0.00560275
SPRR1A small proline-rich protein 1A -0.00558781
PAPOLG poly(A) polymerase gamma -0.00554162
TGFB1 transforming growth factor, beta 1 -0.00553534
ANGEL2 angel homolog 2 (Drosophila) -0.00553296
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.00553234
KIF20A kinesin family member 20A -0.00552175
TNNI2 troponin I type 2 (skeletal, fast) -0.00552062
TGOLN2 trans-golgi network protein 2 -0.00549817
BSG basigin (Ok blood group) -0.00545729
STC2 stanniocalcin 2 -0.00545273
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00542012
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00541568
MYL1 myosin, light chain 1, alkali; skeletal, fast -0.0054128
SLCO4C1 solute carrier organic anion transporter family, member 4C1 -0.00540978
TGFBI transforming growth factor, beta-induced, 68kDa -0.00537565
DEPDC1 DEP domain containing 1 -0.00537481
TP63 tumor protein p63 -0.00537053
TMEM41B transmembrane protein 41B -0.00536945
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.0053655
BDNF brain-derived neurotrophic factor -0.00535967
R3HDM1 R3H domain containing 1 -0.00535331
STAU2 staufen double-stranded RNA binding protein 2 -0.0053485
THNSL2 threonine synthase-like 2 (S. cerevisiae) -0.00534195
SFTPA2 surfactant protein A2 -0.00533092
PKP1 plakophilin 1 -0.00532744
PON2 paraoxonase 2 -0.00531535
NFIC nuclear factor I/C (CCAAT-binding transcription factor) -0.00530334
HLA-B major histocompatibility complex, class I, B -0.0052882
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) -0.00528314
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase -0.00527026
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -0.00526008
PTN pleiotrophin -0.00525856
CCNB2 cyclin B2 -0.00525025
WFDC2 WAP four-disulfide core domain 2 -0.00524834
CDH13 cadherin 13 -0.00524699
LAMP3 lysosomal-associated membrane protein 3 -0.00524395
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 -0.00523154
ZMIZ1 zinc finger, MIZ-type containing 1 -0.00522648
SUSD4 sushi domain containing 4 -0.00522423
MYBPC2 myosin binding protein C, fast type -0.00521122
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00520404
CRABP1 cellular retinoic acid binding protein 1 -0.00520159
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) -0.00519071
CKM creatine kinase, muscle -0.00516864
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00515159
IRAK3 interleukin-1 receptor-associated kinase 3 -0.00514829
ANOS1 anosmin 1 -0.00513934
NNMT nicotinamide N-methyltransferase -0.00513826
GUSB glucuronidase, beta -0.00512035
PRDX2 peroxiredoxin 2 -0.00509993
DEFB1 defensin, beta 1 -0.00509857
LPAR6 lysophosphatidic acid receptor 6 -0.00509635
SLC35E2B solute carrier family 35, member E2B -0.00508466
RCAN1 regulator of calcineurin 1 -0.00507662
HSPB3 heat shock 27kDa protein 3 -0.0050617
ZNF217 zinc finger protein 217 -0.00505413
SRPRA SRP receptor subunit alpha -0.00504985
LUM lumican -0.00503495
TAPBP TAP binding protein (tapasin) -0.00501475
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) -0.00501133
DENND1B DENN/MADD domain containing 1B -0.00500962
MYH2 myosin, heavy chain 2, skeletal muscle, adult -0.00500437
ZBTB16 zinc finger and BTB domain containing 16 -0.00499984
STK32B serine/threonine kinase 32B -0.0049899
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.00498866
GGCT gamma-glutamylcyclotransferase -0.00497135
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 -0.00496163
MYOZ1 myozenin 1 -0.00496068
ALG6 ALG6, alpha-1,3-glucosyltransferase -0.00493999
CSF3R colony stimulating factor 3 receptor (granulocyte) -0.00491669
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.00491034
FECH ferrochelatase -0.00490938
TSPYL1 TSPY-like 1 -0.00490493
CLEC2B C-type lectin domain family 2, member B -0.00489835
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00489103
ACAD8 acyl-CoA dehydrogenase family, member 8 -0.00487991
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -0.00487451
NPTX1 neuronal pentraxin I -0.00487199
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha -0.00486689
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -0.00486507
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.00486286
TNNC1 troponin C type 1 (slow) -0.00485673
RXRA retinoid X receptor, alpha -0.0048543
GPNMB glycoprotein (transmembrane) nmb -0.00485382
ORC1 origin recognition complex, subunit 1 -0.00484594
PSME4 proteasome (prosome, macropain) activator subunit 4 -0.00483854
TNNC2 troponin C type 2 (fast) -0.00482845
MFSD10 major facilitator superfamily domain containing 10 -0.00482681
SC5D sterol-C5-desaturase -0.00482574
IFI44L interferon-induced protein 44-like -0.00482064
CLCA2 chloride channel accessory 2 -0.00481999
KIF11 kinesin family member 11 -0.00481899
TIMP1 TIMP metallopeptidase inhibitor 1 -0.00481835
SELENBP1 selenium binding protein 1 -0.00480878
ZNF750 zinc finger protein 750 -0.00480123
IGFBP6 insulin-like growth factor binding protein 6 -0.00480011
FABP4 fatty acid binding protein 4, adipocyte -0.0047926
TMED5 transmembrane emp24 protein transport domain containing 5 -0.00479233
TFPI2 tissue factor pathway inhibitor 2 -0.00477714
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.00477143
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -0.00477115
TMEM45A transmembrane protein 45A -0.00477058
VEGFA vascular endothelial growth factor A -0.00477046
TRHDE thyrotropin-releasing hormone degrading enzyme -0.00476921
CA3 carbonic anhydrase III -0.00476341
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.00475651
FRY furry homolog (Drosophila) -0.00475541
PDE4A phosphodiesterase 4A, cAMP-specific -0.00475422