FES Gene Set

Dataset Kinase Library Tyrosine Kinome Atlas
Category proteomics
Type kinase
Description FES proto-oncogene, tyrosine kinase|This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.[provided by RefSeq, Jan 2009] (NCBI Entrez Gene Database, 2242)
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100 substrates of the kinase FES from the Kinase Library Tyrosine Kinome Atlas dataset.

Symbol Name Standardized Value
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) 100.0
RABGAP1L RAB GTPase activating protein 1-like 99.98
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 99.94
PTPRH protein tyrosine phosphatase, receptor type, H 99.94
PTPRB protein tyrosine phosphatase, receptor type, B 99.93
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 99.91
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 99.83
TWF1 twinfilin actin binding protein 1 99.82
ZCCHC3 zinc finger, CCHC domain containing 3 99.8
LY6G6F lymphocyte antigen 6 complex, locus G6F 99.72
DPH6 diphthamine biosynthesis 6 99.67
PLCL2 phospholipase C-like 2 99.59
TEX2 testis expressed 2 99.56
KMT5A lysine methyltransferase 5A 99.54
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 99.5
UBE2E2 ubiquitin-conjugating enzyme E2E 2 99.47
UBE2E1 ubiquitin-conjugating enzyme E2E 1 99.47
UBE2E3 ubiquitin-conjugating enzyme E2E 3 99.47
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 99.39
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa 99.28
SIPA1L1 signal-induced proliferation-associated 1 like 1 99.26
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 99.135
STING1 stimulator of interferon response cGAMP interactor 1 99.06
CHD2 chromodomain helicase DNA binding protein 2 99.06
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 99.04
EEIG1 estrogen-induced osteoclastogenesis regulator 1 99.02
FAF2 Fas associated factor family member 2 99.01
ELP3 elongator acetyltransferase complex subunit 3 98.93
FHOD1 formin homology 2 domain containing 1 98.9
FBXO9 F-box protein 9 98.9
MTO1 mitochondrial tRNA translation optimization 1 98.77
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 98.77
ZNF512 zinc finger protein 512 98.75
R3HCC1L R3H domain and coiled-coil containing 1-like 98.73
JAML junction adhesion molecule like 98.71
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 98.69
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 98.67
CMKLR1 chemerin chemokine-like receptor 1 98.62
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 98.55
ARRDC3 arrestin domain containing 3 98.51
TWF2 twinfilin actin binding protein 2 98.47
MCEMP1 mast cell-expressed membrane protein 1 98.43
FPR2 formyl peptide receptor 2 98.36
ENO2 enolase 2 (gamma, neuronal) 98.32
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 98.27
FAM168A family with sequence similarity 168, member A 98.23
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 98.1
GSDMD gasdermin D 98.09
RIC1 RAB6A GEF complex partner 1 98.07
FCRL4 Fc receptor-like 4 97.96
PARVG parvin, gamma 97.94
TRAPPC9 trafficking protein particle complex 9 97.86
FYB2 FYN binding protein 2 97.83
CNOT9 CCR4-NOT transcription complex subunit 9 97.79
RALY RALY heterogeneous nuclear ribonucleoprotein 97.77
FDFT1 farnesyl-diphosphate farnesyltransferase 1 97.62
CNBD2 cyclic nucleotide binding domain containing 2 97.61
GREB1 growth regulation by estrogen in breast cancer 1 97.57
CD244 CD244 molecule, natural killer cell receptor 2B4 97.56
NUDT5 nudix (nucleoside diphosphate linked moiety X)-type motif 5 97.51
RPS10 ribosomal protein S10 97.48
RPS10-NUDT3 RPS10-NUDT3 readthrough 97.48
CFAP97 cilia and flagella associated protein 97 97.44
TERB1 telomere repeat binding bouquet formation protein 1 97.42
PRMT3 protein arginine methyltransferase 3 97.35
CORO1A coronin, actin binding protein, 1A 97.35
KLC3 kinesin light chain 3 97.31
F5 coagulation factor V (proaccelerin, labile factor) 97.2
FCRL6 Fc receptor-like 6 97.18
ZC3HAV1L zinc finger CCCH-type, antiviral 1-like 97.16
GCHFR GTP cyclohydrolase I feedback regulator 97.09
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 97.05
PUDP pseudouridine 5'-phosphatase 97.02
RGS19 regulator of G-protein signaling 19 96.915
MCRIP1 MAPK regulated corepressor interacting protein 1 96.87
MFAP3L microfibrillar-associated protein 3-like 96.81
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 96.81
IKZF3 IKAROS family zinc finger 3 (Aiolos) 96.72
STK38 serine/threonine kinase 38 96.7
BDKRB2 bradykinin receptor B2 96.69
CAPN2 calpain 2, (m/II) large subunit 96.63
RIOK1 RIO kinase 1 96.48
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 96.43
YEATS2 YEATS domain containing 2 96.37
PRAM1 PML-RARA regulated adaptor molecule 1 96.35
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 96.32
FCRL3 Fc receptor-like 3 96.3
CLMP CXADR-like membrane protein 96.3
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 96.275
PILRA paired immunoglobin-like type 2 receptor alpha 96.24
CKAP4 cytoskeleton-associated protein 4 96.23
PTPRJ protein tyrosine phosphatase, receptor type, J 96.205
PRPS1 phosphoribosyl pyrophosphate synthetase 1 96.15
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 96.13
DOK3 docking protein 3 96.1
EEIG2 EEIG family member 2 96.08
C9ORF78 chromosome 9 open reading frame 78 96.04
CZIB CXXC motif containing zinc binding protein 96.0
COG3 component of oligomeric golgi complex 3 95.99
CKS1B CDC28 protein kinase regulatory subunit 1B 95.97