FES Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description FES proto-oncogene, tyrosine kinase|This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.[provided by RefSeq, Jan 2009] (NCBI Entrez Gene Database, 2242)
External Link https://ncbi.nlm.nih.gov/gene/2242
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Genes

499 genes differentially expressed following the FES gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
HSPA1A heat shock 70kDa protein 1A 0.0154825
IFI27 interferon, alpha-inducible protein 27 0.0133191
DLK1 delta-like 1 homolog (Drosophila) 0.0126041
EIF5A eukaryotic translation initiation factor 5A 0.0121111
PELI1 pellino E3 ubiquitin protein ligase 1 0.0114921
KLF6 Kruppel-like factor 6 0.0111079
SH3TC1 SH3 domain and tetratricopeptide repeats 1 0.0110594
RGS5 regulator of G-protein signaling 5 0.0108978
BEX4 brain expressed, X-linked 4 0.0108476
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.0108444
SPRED2 sprouty-related, EVH1 domain containing 2 0.0101463
CD1E CD1e molecule 0.00998981
AREG amphiregulin 0.00968509
PROM1 prominin 1 0.00948767
ISG15 ISG15 ubiquitin-like modifier 0.00945752
NPY neuropeptide Y 0.00943776
SCGB2A1 secretoglobin, family 2A, member 1 0.00939179
BAMBI BMP and activin membrane-bound inhibitor 0.00929661
ETFB electron-transfer-flavoprotein, beta polypeptide 0.00918889
CA2 carbonic anhydrase II 0.00900138
MVP major vault protein 0.00899767
IFI6 interferon, alpha-inducible protein 6 0.00896349
H1-0 H1.0 linker histone 0.00875377
OXA1L oxidase (cytochrome c) assembly 1-like 0.00872913
CXCL10 chemokine (C-X-C motif) ligand 10 0.00859604
NR1H2 nuclear receptor subfamily 1, group H, member 2 0.00854719
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00842641
OXTR oxytocin receptor 0.00834355
MX1 MX dynamin-like GTPase 1 0.00826226
VNN1 vanin 1 0.00818486
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 0.00817968
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.00811387
ADM adrenomedullin 0.00803302
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.00801287
TAGLN2 transgelin 2 0.00797691
CD1B CD1b molecule 0.00796812
GAL galanin/GMAP prepropeptide 0.00794339
PBX3 pre-B-cell leukemia homeobox 3 0.00779394
ZMYM2 zinc finger, MYM-type 2 0.00768639
NEFM neurofilament, medium polypeptide 0.0076861
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.00767602
PEG10 paternally expressed 10 0.00766608
DNTT DNA nucleotidylexotransferase 0.00764447
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00763529
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00761506
ASRGL1 asparaginase like 1 0.00761316
HSPB1 heat shock 27kDa protein 1 0.00760309
PSAP prosaposin 0.00755099
ATF3 activating transcription factor 3 0.00748741
EGR3 early growth response 3 0.00746823
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00746358
DMTF1 cyclin D binding myb-like transcription factor 1 0.00736718
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00731467
HIST3H2A histone cluster 3, H2a 0.00730844
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00729013
IL6R interleukin 6 receptor 0.00727637
RGCC regulator of cell cycle 0.00719408
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00717841
PEG3 paternally expressed 3 0.00717439
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00712055
WARS1 tryptophanyl-tRNA synthetase 1 0.0070814
HLA-B major histocompatibility complex, class I, B 0.00702294
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.00697423
COCH cochlin 0.0069464
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.00692887
KLHL24 kelch-like family member 24 0.00692762
ARMCX1 armadillo repeat containing, X-linked 1 0.00690848
EFNA1 ephrin-A1 0.00689143
SELL selectin L 0.00687998
UBE2S ubiquitin-conjugating enzyme E2S 0.00687549
GSTP1 glutathione S-transferase pi 1 0.00678906
S100A10 S100 calcium binding protein A10 0.0067843
TMEM131L transmembrane 131 like 0.0067602
RRAS2 related RAS viral (r-ras) oncogene homolog 2 0.00675964
FOLR1 folate receptor 1 (adult) 0.00674065
MEG3 maternally expressed 3 (non-protein coding) 0.00672541
RGS4 regulator of G-protein signaling 4 0.00671293
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.00671035
PDGFA platelet-derived growth factor alpha polypeptide 0.00670027
MOAP1 modulator of apoptosis 1 0.00668422
RSL1D1 ribosomal L1 domain containing 1 0.00668217
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 0.00665068
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 0.00655992
FXR1 fragile X mental retardation, autosomal homolog 1 0.00654892
TAC1 tachykinin, precursor 1 0.00654511
SLC22A18 solute carrier family 22, member 18 0.0065043
RTN2 reticulon 2 0.00650341
HAL histidine ammonia-lyase 0.00648666
ARMCX2 armadillo repeat containing, X-linked 2 0.00648604
NCOA3 nuclear receptor coactivator 3 0.00645761
EPCAM epithelial cell adhesion molecule 0.00642418
MYH10 myosin, heavy chain 10, non-muscle 0.00641722
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00638223
MRPL23 mitochondrial ribosomal protein L23 0.00637506
MDK midkine (neurite growth-promoting factor 2) 0.0063659
TFPI2 tissue factor pathway inhibitor 2 0.00633927
TNIP1 TNFAIP3 interacting protein 1 0.00629949
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00628536
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.00626721
CRABP1 cellular retinoic acid binding protein 1 0.00626086
RFTN1 raftlin, lipid raft linker 1 0.0062493
ATF4 activating transcription factor 4 0.00622444
DDR2 discoidin domain receptor tyrosine kinase 2 0.00617369
THBS2 thrombospondin 2 0.00616762
TEX10 testis expressed 10 0.00616633
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00613451
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00610544
NAP1L1 nucleosome assembly protein 1-like 1 0.00607329
TUBB2A tubulin, beta 2A class IIa 0.0060696
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.00598023
GBP2 guanylate binding protein 2, interferon-inducible 0.00597554
GAB2 GRB2-associated binding protein 2 0.00595672
ARMCX3 armadillo repeat containing, X-linked 3 0.00594843
CYB561 cytochrome b561 0.00594487
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 0.0059239
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.0059097
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00590531
GAS7 growth arrest-specific 7 0.00589935
RAP1GAP2 RAP1 GTPase activating protein 2 0.00589347
IRF1 interferon regulatory factor 1 0.00589345
TESC tescalcin 0.00588837
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00588521
TCTA T-cell leukemia translocation altered 0.00587435
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.00586719
IER5 immediate early response 5 0.00586517
MTUS1 microtubule associated tumor suppressor 1 0.00586472
JUNB jun B proto-oncogene 0.00586357
PRMT1 protein arginine methyltransferase 1 0.00586036
AKAP8L A kinase (PRKA) anchor protein 8-like 0.00585485
EIF3F eukaryotic translation initiation factor 3, subunit F 0.00584417
STMN2 stathmin 2 0.00584179
SGK1 serum/glucocorticoid regulated kinase 1 0.00583813
CD99 CD99 molecule 0.00583438
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00581613
FN1 fibronectin 1 0.00580948
PON3 paraoxonase 3 0.00580819
R3HDM4 R3H domain containing 4 0.00580553
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00579531
SMCO4 single-pass membrane protein with coiled-coil domains 4 0.00579002
GPX7 glutathione peroxidase 7 0.00576086
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.00571562
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.00569364
MPHOSPH8 M-phase phosphoprotein 8 0.00568624
VCAN versican 0.00564426
CLDN7 claudin 7 0.00564377
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00563891
SERHL2 serine hydrolase-like 2 0.00562628
MELK maternal embryonic leucine zipper kinase 0.00561101
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.00558004
CD36 CD36 molecule (thrombospondin receptor) 0.00557373
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00556051
KLF4 Kruppel-like factor 4 (gut) 0.00555911
STAT1 signal transducer and activator of transcription 1, 91kDa 0.00555154
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00554917
KLF10 Kruppel-like factor 10 0.00554261
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.00553489
XIC X chromosome inactivation center 0.00553326
BST2 bone marrow stromal cell antigen 2 0.00552895
BAD BCL2-associated agonist of cell death 0.00552424
RPL36 ribosomal protein L36 0.00551319
PNMA8A PNMA family member 8A 0.0055094
IRS2 insulin receptor substrate 2 0.00549473
ACAA1 acetyl-CoA acyltransferase 1 0.00549395
FLT3 fms-related tyrosine kinase 3 0.00548795
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.00548681
GPX3 glutathione peroxidase 3 0.00548625
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 0.00545921
RUNDC3B RUN domain containing 3B 0.00545531
GREB1 growth regulation by estrogen in breast cancer 1 0.00542402
IFI44L interferon-induced protein 44-like 0.00541928
ZNF83 zinc finger protein 83 0.00540043
IRF7 interferon regulatory factor 7 0.00538635
MME membrane metallo-endopeptidase 0.00534923
SIRT3 sirtuin 3 0.00534015
MCL1 myeloid cell leukemia 1 0.00533122
HSPH1 heat shock 105kDa/110kDa protein 1 0.00532178
IGBP1 immunoglobulin (CD79A) binding protein 1 0.00531238
BSG basigin (Ok blood group) 0.00528917
IER3 immediate early response 3 0.00526392
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.0052553
DSG2 desmoglein 2 0.00525277
SELENOW selenoprotein W 0.00525063
ZFP36L2 ZFP36 ring finger protein-like 2 0.00525058
ADGRE1 adhesion G protein-coupled receptor E1 0.00523939
OGDHL oxoglutarate dehydrogenase-like 0.00523781
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00522685
SFRP1 secreted frizzled-related protein 1 0.00520128
RNF7 ring finger protein 7 0.00519507
FMO5 flavin containing monooxygenase 5 0.00519214
EGR2 early growth response 2 0.0051893
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00518274
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00517716
WEE1 WEE1 G2 checkpoint kinase 0.00517163
FKBP2 FK506 binding protein 2, 13kDa 0.00515985
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00515973
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 0.00514777
TUBB2B tubulin, beta 2B class IIb 0.00513844
MFAP2 microfibrillar-associated protein 2 0.00513503
SPRY4 sprouty homolog 4 (Drosophila) 0.00511858
PLLP plasmolipin 0.00511799
FGF9 fibroblast growth factor 9 0.00510929
PRMT5 protein arginine methyltransferase 5 0.0051061
LETMD1 LETM1 domain containing 1 0.00509149
TSC22D2 TSC22 domain family, member 2 0.00504982
HAND2-AS1 HAND2 antisense RNA 1 (head to head) 0.00504438
MYBPC1 myosin binding protein C, slow type 0.00504076
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.00502696
SAP30BP SAP30 binding protein 0.00501806
MSRB2 methionine sulfoxide reductase B2 0.00500509
QPRT quinolinate phosphoribosyltransferase 0.00500273
CD81 CD81 molecule 0.00497658
KLK5 kallikrein-related peptidase 5 0.00496409
IL17RB interleukin 17 receptor B 0.00495043
E2F2 E2F transcription factor 2 0.00494593
IVNS1ABP influenza virus NS1A binding protein 0.00494044
NOP53 NOP53 ribosome biogenesis factor 0.00494026
TLE4 transducin-like enhancer of split 4 0.00493481
NID1 nidogen 1 0.00493026
DDT D-dopachrome tautomerase 0.00492051
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle 0.00489827
RHOC ras homolog family member C 0.00489297
REEP1 receptor accessory protein 1 0.00488376
CTSD cathepsin D 0.00487058
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00487006
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.00486678
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.00485405
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 0.00484871
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.00484727
RABGAP1L RAB GTPase activating protein 1-like 0.00484413
ECM1 extracellular matrix protein 1 0.00484342
CYB5R2 cytochrome b5 reductase 2 0.00484333
AZIN1 antizyme inhibitor 1 0.00484265
SP100 SP100 nuclear antigen 0.00483803
AKIRIN1 akirin 1 0.00483493
FAM174B family with sequence similarity 174, member B 0.00482648
MGLL monoglyceride lipase 0.00482452
NEU1 sialidase 1 (lysosomal sialidase) 0.00481855
RFC2 replication factor C (activator 1) 2, 40kDa 0.00481754
EXT1 exostosin glycosyltransferase 1 0.00480836
FXYD2 FXYD domain containing ion transport regulator 2 0.00480809
PPP1R16B protein phosphatase 1, regulatory subunit 16B 0.00480794
FRY furry homolog (Drosophila) 0.00480675
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.00479635
RPP38 ribonuclease P/MRP 38kDa subunit 0.00479563
MIA melanoma inhibitory activity 0.00479062
C14ORF132 chromosome 14 open reading frame 132 0.00478976
TTC17 tetratricopeptide repeat domain 17 0.00478509
EDN1 endothelin 1 0.00478303
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.004783
SARS1 seryl-tRNA synthetase 1 0.00478132

decreased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 -0.0188499
S100P S100 calcium binding protein P -0.0186137
TXNDC9 thioredoxin domain containing 9 -0.0184689
PCNA proliferating cell nuclear antigen -0.0175822
S100A9 S100 calcium binding protein A9 -0.016463
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.0152675
OLFM4 olfactomedin 4 -0.0128741
KRT13 keratin 13, type I -0.0121114
S100A2 S100 calcium binding protein A2 -0.0119866
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.0110828
CPA3 carboxypeptidase A3 (mast cell) -0.0109984
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0104545
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.0104049
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0100583
CD320 CD320 molecule -0.00988918
LCN2 lipocalin 2 -0.00978946
SUB1 SUB1 homolog (S. cerevisiae) -0.00940078
CFD complement factor D (adipsin) -0.00926749
SLPI secretory leukocyte peptidase inhibitor -0.00925846
TMEM45A transmembrane protein 45A -0.00925029
LTF lactotransferrin -0.00913217
FGFR3 fibroblast growth factor receptor 3 -0.00909102
PMP22 peripheral myelin protein 22 -0.00904863
SRGN serglycin -0.00903712
TPSAB1 tryptase alpha/beta 1 -0.00885605
AKR1C3 aldo-keto reductase family 1, member C3 -0.00871637
DEFA4 defensin, alpha 4, corticostatin -0.00858708
CSTA cystatin A (stefin A) -0.00846485
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.00842394
AQP3 aquaporin 3 (Gill blood group) -0.00828543
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00819968
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.00818282
ADARB1 adenosine deaminase, RNA-specific, B1 -0.00817903
CST7 cystatin F (leukocystatin) -0.00815485
FBLN1 fibulin 1 -0.00808585
LEPR leptin receptor -0.00807612
PCOLCE2 procollagen C-endopeptidase enhancer 2 -0.00806773
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00795779
LIMCH1 LIM and calponin homology domains 1 -0.0079552
SPRR3 small proline-rich protein 3 -0.00785206
PI3 peptidase inhibitor 3, skin-derived -0.00782309
LTBP1 latent transforming growth factor beta binding protein 1 -0.00772375
CCL4 chemokine (C-C motif) ligand 4 -0.00771991
MDFIC MyoD family inhibitor domain containing -0.00769738
TYMS thymidylate synthetase -0.00767959
PHACTR2 phosphatase and actin regulator 2 -0.00767847
LYZ lysozyme -0.00765779
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00760454
CLC Charcot-Leyden crystal galectin -0.00759746
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.00748776
WNT5A wingless-type MMTV integration site family, member 5A -0.00747885
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -0.00747843
VBP1 von Hippel-Lindau binding protein 1 -0.00739743
PIR pirin (iron-binding nuclear protein) -0.00737755
ADORA2B adenosine A2b receptor -0.00732875
KRT15 keratin 15, type I -0.00732622
TNC tenascin C -0.00731859
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -0.00730021
IGFBP5 insulin-like growth factor binding protein 5 -0.00729742
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -0.00723974
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00723594
APMAP adipocyte plasma membrane associated protein -0.00722196
KRT6A keratin 6A, type II -0.00719991
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) -0.00716573
EPHA3 EPH receptor A3 -0.00715899
MCM6 minichromosome maintenance complex component 6 -0.00714888
NELL2 NEL-like 2 (chicken) -0.00714021
KLRB1 killer cell lectin-like receptor subfamily B, member 1 -0.00712766
PLN phospholamban -0.00709976
COL6A1 collagen, type VI, alpha 1 -0.00694583
CXCL6 chemokine (C-X-C motif) ligand 6 -0.00693316
DHCR24 24-dehydrocholesterol reductase -0.00692595
PDE4D phosphodiesterase 4D, cAMP-specific -0.00691751
XCL1 chemokine (C motif) ligand 1 -0.00691649
BHLHE41 basic helix-loop-helix family, member e41 -0.00687442
GPM6B glycoprotein M6B -0.00684707
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.00684291
KIF20A kinesin family member 20A -0.00680308
TMEM131 transmembrane protein 131 -0.00679262
UPK1B uroplakin 1B -0.0067876
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b -0.00677978
TMEM106C transmembrane protein 106C -0.00675175
TGFA transforming growth factor, alpha -0.00674857
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -0.00672816
CCL2 chemokine (C-C motif) ligand 2 -0.00672112
FRZB frizzled-related protein -0.00665847
NDNF neuron-derived neurotrophic factor -0.0066299
TENT4A terminal nucleotidyltransferase 4A -0.00660204
COL6A3 collagen, type VI, alpha 3 -0.00659814
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.00659266
S100A12 S100 calcium binding protein A12 -0.00657969
ELP1 elongator acetyltransferase complex subunit 1 -0.00656408
PBX1 pre-B-cell leukemia homeobox 1 -0.00651842
C1GALT1C1 C1GALT1-specific chaperone 1 -0.00651307
CENPU centromere protein U -0.00651057
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase -0.00647448
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.00644972
FOXD1 forkhead box D1 -0.00644777
ACD adrenocortical dysplasia homolog (mouse) -0.006431
UST uronyl-2-sulfotransferase -0.00639802
CADPS2 Ca++-dependent secretion activator 2 -0.0063942
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.00638558
SETBP1 SET binding protein 1 -0.00630474
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -0.00629725
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide -0.00629547
F13A1 coagulation factor XIII, A1 polypeptide -0.00626839
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00626445
TRPS1 trichorhinophalangeal syndrome I -0.00625795
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.00625606
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -0.00624013
NUSAP1 nucleolar and spindle associated protein 1 -0.00623703
ELANE elastase, neutrophil expressed -0.00623602
MTCL1 microtubule crosslinking factor 1 -0.00623404
RAB23 RAB23, member RAS oncogene family -0.00619287
DUT deoxyuridine triphosphatase -0.00619188
CFH complement factor H -0.00618755
ALOX5 arachidonate 5-lipoxygenase -0.00612001
TSPAN13 tetraspanin 13 -0.00611916
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00610765
TYROBP TYRO protein tyrosine kinase binding protein -0.00607982
PRF1 perforin 1 (pore forming protein) -0.00607087
CCN2 cellular communication network factor 2 -0.00606847
LY6D lymphocyte antigen 6 complex, locus D -0.00605232
AGR2 anterior gradient 2 -0.00604224
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -0.00603333
FNDC3B fibronectin type III domain containing 3B -0.00599466
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.00598763
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 -0.00598112
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00597858
TGM2 transglutaminase 2 -0.00597843
SPRR1B small proline-rich protein 1B -0.00595921
ZNF423 zinc finger protein 423 -0.00594461
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00592342
STK39 serine threonine kinase 39 -0.00591057
CCL13 chemokine (C-C motif) ligand 13 -0.00590756
VCAM1 vascular cell adhesion molecule 1 -0.00590333
RRM2 ribonucleotide reductase M2 -0.00587546
TRIM16 tripartite motif containing 16 -0.0058702
PPL periplakin -0.00584577
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.00580982
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -0.0057883
TRIP13 thyroid hormone receptor interactor 13 -0.00578756
CPB1 carboxypeptidase B1 (tissue) -0.00577942
PGAM1 phosphoglycerate mutase 1 (brain) -0.00577452
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -0.00576684
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -0.00575005
FERMT1 fermitin family member 1 -0.00571004
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.00569948
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) -0.00566266
MFAP4 microfibrillar-associated protein 4 -0.00563065
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -0.00560774
RPA3 replication protein A3, 14kDa -0.00560588
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.00560411
PLTP phospholipid transfer protein -0.00560341
ENO2 enolase 2 (gamma, neuronal) -0.00557948
SATB2 SATB homeobox 2 -0.00556509
CRNKL1 crooked neck pre-mRNA splicing factor 1 -0.00555998
SLC38A1 solute carrier family 38, member 1 -0.00555438
MYL1 myosin, light chain 1, alkali; skeletal, fast -0.00554361
H2AFV H2A histone family, member V -0.00551435
PANK2 pantothenate kinase 2 -0.00550416
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -0.00549813
NCF4 neutrophil cytosolic factor 4, 40kDa -0.00546964
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) -0.00546848
CCNE2 cyclin E2 -0.00546124
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) -0.00544767
RHCG Rh family, C glycoprotein -0.00544383
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -0.00543766
STK26 serine/threonine protein kinase 26 -0.00543415
AKR1C1 aldo-keto reductase family 1, member C1 -0.00543191
ADIRF adipogenesis regulatory factor -0.00542536
TBC1D31 TBC1 domain family, member 31 -0.00542392
CTSW cathepsin W -0.00540262
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) -0.00539606
CAND1 cullin-associated and neddylation-dissociated 1 -0.00539513
COL1A2 collagen, type I, alpha 2 -0.00539021
BTBD3 BTB (POZ) domain containing 3 -0.00537565
CAMP cathelicidin antimicrobial peptide -0.00536627
CHKB choline kinase beta -0.00535167
TNS3 tensin 3 -0.00534942
PLPP3 phospholipid phosphatase 3 -0.0053439
DEFA5 defensin, alpha 5, Paneth cell-specific -0.00533328
IRF2 interferon regulatory factor 2 -0.00533102
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00533079
MGAM maltase-glucoamylase -0.00533057
PDZRN3 PDZ domain containing ring finger 3 -0.0053239
POPDC3 popeye domain containing 3 -0.00530298
EPN2 epsin 2 -0.0053008
REV1 REV1, polymerase (DNA directed) -0.00529622
LEPROTL1 leptin receptor overlapping transcript-like 1 -0.00529207
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -0.00527926
SLCO1B3 solute carrier organic anion transporter family, member 1B3 -0.00527636
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00527438
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.0052694
PKM pyruvate kinase, muscle -0.00526173
RHOB ras homolog family member B -0.00525991
SVIL supervillin -0.00525012
OSMR oncostatin M receptor -0.00524844
PCSK6 proprotein convertase subtilisin/kexin type 6 -0.00524138
C1QB complement component 1, q subcomponent, B chain -0.00523948
PSCA prostate stem cell antigen -0.00523796
SNAI2 snail family zinc finger 2 -0.00522665
MANSC1 MANSC domain containing 1 -0.00520395
CYTL1 cytokine-like 1 -0.00520377
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.00520259
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00519952
MPO myeloperoxidase -0.00518894
SORD sorbitol dehydrogenase -0.00517217
NDC80 NDC80 kinetochore complex component -0.00516339
KIF23 kinesin family member 23 -0.005158
PTCH1 patched 1 -0.00513179
DEK DEK proto-oncogene -0.0051235
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 -0.00512237
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 -0.00511098
PLBD1 phospholipase B domain containing 1 -0.00510086
RXYLT1 ribitol xylosyltransferase 1 -0.00509811
TOX3 TOX high mobility group box family member 3 -0.00509516
AZU1 azurocidin 1 -0.00509183
KRT17 keratin 17, type I -0.00509086
ICMT isoprenylcysteine carboxyl methyltransferase -0.00508187
JAG1 jagged 1 -0.00507948
MMP7 matrix metallopeptidase 7 -0.00507933
NMB neuromedin B -0.00507853
RAB32 RAB32, member RAS oncogene family -0.00507471
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -0.0050691
HOXB2 homeobox B2 -0.00504789
DUOX2 dual oxidase 2 -0.00504152
CLCA4 chloride channel accessory 4 -0.00504139
PRRX1 paired related homeobox 1 -0.00503407
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -0.00502781
ZMIZ2 zinc finger, MIZ-type containing 2 -0.00502725
PTGES prostaglandin E synthase -0.00502576
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.00502115
PRTN3 proteinase 3 -0.00501462
MMP10 matrix metallopeptidase 10 -0.00500915
HHEX hematopoietically expressed homeobox -0.00497734
CD38 CD38 molecule -0.00496558
SOX9 SRY (sex determining region Y)-box 9 -0.00495204
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 -0.00495141
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.00494453
CLU clusterin -0.00494056
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.00493564
EGLN3 egl-9 family hypoxia-inducible factor 3 -0.00491464
FZD6 frizzled class receptor 6 -0.00489777
GFAP glial fibrillary acidic protein -0.00489697
SCARA3 scavenger receptor class A, member 3 -0.00489426
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) -0.00488614
BPI bactericidal/permeability-increasing protein -0.00488419
ADAMDEC1 ADAM-like, decysin 1 -0.00488387