FFAT motif binding Gene Set

Dataset GO Molecular Function Annotations 2025
Category structural or functional annotations
Type molecular function
Description Interacting selectively and non-covalently with the FFAT motif, a short motif containing diphenylalanine in an acidic tract that targets proteins to the cytosolic surface of the ER and to the nuclear membrane by binding directly to members of the VAP (VAMP-associated protein) protein family. (Gene Ontology, GO_0033149)
External Link http://amigo.geneontology.org/amigo/term/GO:0033149
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Genes

3 genes performing the FFAT motif binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

Symbol Name
MOSPD2 motile sperm domain containing 2
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C