| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | fibroblast growth factor 2 (basic)|The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2247) |
| External Link | https://ncbi.nlm.nih.gov/gene/2247 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the FGF2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| XIC | X chromosome inactivation center | 0.0194713 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.0173915 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0169476 |
| STK10 | serine/threonine kinase 10 | 0.013933 |
| NVL | nuclear VCP-like | 0.0133276 |
| BST2 | bone marrow stromal cell antigen 2 | 0.0130259 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.0126729 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.0121991 |
| KRT14 | keratin 14, type I | 0.0111659 |
| S100A7 | S100 calcium binding protein A7 | 0.0111541 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.0107587 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0102398 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0101395 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.0100562 |
| DEFB1 | defensin, beta 1 | 0.0100282 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00995396 |
| ANXA6 | annexin A6 | 0.00973481 |
| XPO7 | exportin 7 | 0.00964337 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00961722 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.00956845 |
| S100A2 | S100 calcium binding protein A2 | 0.0094321 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00936268 |
| QPRT | quinolinate phosphoribosyltransferase | 0.0092981 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00923089 |
| PODXL | podocalyxin-like | 0.00922555 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00917318 |
| KRT17 | keratin 17, type I | 0.00905931 |
| PEG10 | paternally expressed 10 | 0.00904239 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00903266 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00885007 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0088211 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00876922 |
| RB1 | retinoblastoma 1 | 0.00876258 |
| GPC3 | glypican 3 | 0.00868658 |
| FST | follistatin | 0.008642 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00861579 |
| PDZK1 | PDZ domain containing 1 | 0.00855949 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | 0.00853117 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00851552 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00849241 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.0084649 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00835501 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00833814 |
| CGA | glycoprotein hormones, alpha polypeptide | 0.00831104 |
| PLAT | plasminogen activator, tissue | 0.00831095 |
| CDCA4 | cell division cycle associated 4 | 0.00827828 |
| KRT5 | keratin 5, type II | 0.00816823 |
| OGDHL | oxoglutarate dehydrogenase-like | 0.00816123 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00808575 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00806194 |
| CALML3 | calmodulin-like 3 | 0.00801269 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.00800161 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00797759 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00786286 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | 0.00782195 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00781455 |
| GAS2 | growth arrest-specific 2 | 0.00778517 |
| GOT1 | glutamic-oxaloacetic transaminase 1, soluble | 0.00768419 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00760236 |
| MAL | mal, T-cell differentiation protein | 0.00750317 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.00746384 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00744882 |
| SIX1 | SIX homeobox 1 | 0.00744117 |
| IFI44 | interferon-induced protein 44 | 0.00738693 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.00738445 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.007311 |
| COL3A1 | collagen, type III, alpha 1 | 0.00720876 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.00720042 |
| STYXL1 | serine/threonine/tyrosine interacting-like 1 | 0.00719333 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0071838 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00711599 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 0.00710931 |
| PRPF4 | pre-mRNA processing factor 4 | 0.0070839 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.00704459 |
| WDR61 | WD repeat domain 61 | 0.00700798 |
| POSTN | periostin, osteoblast specific factor | 0.00699261 |
| FMO1 | flavin containing monooxygenase 1 | 0.00694625 |
| VNN1 | vanin 1 | 0.00691461 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00689256 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.0068924 |
| GLO1 | glyoxalase I | 0.00686404 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.00685434 |
| NID1 | nidogen 1 | 0.00685188 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 0.00685123 |
| CHMP6 | charged multivesicular body protein 6 | 0.00683294 |
| PUDP | pseudouridine 5'-phosphatase | 0.00682179 |
| LIMA1 | LIM domain and actin binding 1 | 0.00681403 |
| LRRC17 | leucine rich repeat containing 17 | 0.00681185 |
| RNASEH2A | ribonuclease H2, subunit A | 0.00680712 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0067688 |
| HOPX | HOP homeobox | 0.00670809 |
| CYTL1 | cytokine-like 1 | 0.00670804 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00666523 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 0.00663907 |
| VCAN | versican | 0.00662148 |
| OXTR | oxytocin receptor | 0.00657906 |
| DENND2B | DENN domain containing 2B | 0.00656406 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.00656047 |
| ELOVL4 | ELOVL fatty acid elongase 4 | 0.0065433 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00652115 |
| IL2RG | interleukin 2 receptor, gamma | 0.0065034 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.006502 |
| LCN2 | lipocalin 2 | 0.00649789 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.00647688 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.00646786 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00646655 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00645862 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 | 0.00645827 |
| MMP11 | matrix metallopeptidase 11 | 0.00645793 |
| POFUT1 | protein O-fucosyltransferase 1 | 0.00644761 |
| DSP | desmoplakin | 0.006397 |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | 0.0063889 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.00638608 |
| MEF2A | myocyte enhancer factor 2A | 0.00637333 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 0.00636806 |
| ZIC1 | Zic family member 1 | 0.0063462 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00629537 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | 0.00629122 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00626964 |
| SDC1 | syndecan 1 | 0.00626743 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | 0.00626736 |
| THBS2 | thrombospondin 2 | 0.00626463 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00623706 |
| OAZ1 | ornithine decarboxylase antizyme 1 | 0.00623286 |
| DUSP22 | dual specificity phosphatase 22 | 0.00622822 |
| IER2 | immediate early response 2 | 0.0062134 |
| OLFML3 | olfactomedin-like 3 | 0.00620742 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00617518 |
| FRZB | frizzled-related protein | 0.00616121 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00614856 |
| TJP2 | tight junction protein 2 | 0.00614376 |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 | 0.00613808 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00611641 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.00609571 |
| KRT10 | keratin 10, type I | 0.00609231 |
| DIPK1A | divergent protein kinase domain 1A | 0.00608341 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 0.00607811 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00607525 |
| C5ORF15 | chromosome 5 open reading frame 15 | 0.00605142 |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.00604113 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | 0.00602388 |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P | 0.00601337 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | 0.00599784 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 0.00598502 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 0.0059433 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00592418 |
| MOCS2 | molybdenum cofactor synthesis 2 | 0.00590564 |
| DCN | decorin | 0.00590425 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00590384 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.00589952 |
| RGS4 | regulator of G-protein signaling 4 | 0.00589354 |
| THBS1 | thrombospondin 1 | 0.00588604 |
| RPS5 | ribosomal protein S5 | 0.00588331 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00587687 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 0.00587509 |
| DMD | dystrophin | 0.00585132 |
| ADI1 | acireductone dioxygenase 1 | 0.00584696 |
| LAMA2 | laminin, alpha 2 | 0.00582531 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00580563 |
| ARG1 | arginase 1 | 0.00578447 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.00578034 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 0.0057746 |
| PHTF2 | putative homeodomain transcription factor 2 | 0.00576499 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00576148 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.00576036 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.00574211 |
| TMEM45A | transmembrane protein 45A | 0.00574184 |
| FAAP100 | FA core complex associated protein 100 | 0.00571887 |
| ACSF2 | acyl-CoA synthetase family member 2 | 0.00571524 |
| SMAD6 | SMAD family member 6 | 0.00571471 |
| GUK1 | guanylate kinase 1 | 0.00571184 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | 0.00568943 |
| MGMT | O-6-methylguanine-DNA methyltransferase | 0.00568451 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00565773 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | 0.0056431 |
| SNAP23 | synaptosomal-associated protein, 23kDa | 0.00563878 |
| RAB4A | RAB4A, member RAS oncogene family | 0.0056349 |
| MRPL17 | mitochondrial ribosomal protein L17 | 0.00562734 |
| EMX2 | empty spiracles homeobox 2 | 0.00562528 |
| IFI35 | interferon-induced protein 35 | 0.00562403 |
| PLIN3 | perilipin 3 | 0.00559472 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | 0.00557977 |
| CIRBP | cold inducible RNA binding protein | 0.00556886 |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 0.00555364 |
| METTL7A | methyltransferase like 7A | 0.00554906 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 | 0.00554758 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00554507 |
| COA3 | cytochrome c oxidase assembly factor 3 | 0.00553355 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.00551423 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00550476 |
| ATP11B | ATPase, class VI, type 11B | 0.00549702 |
| COL16A1 | collagen, type XVI, alpha 1 | 0.00548232 |
| GPR65 | G protein-coupled receptor 65 | 0.00545013 |
| IFI30 | interferon, gamma-inducible protein 30 | 0.00543842 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 0.0054343 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00541003 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | 0.00539694 |
| KRT15 | keratin 15, type I | 0.00538182 |
| PTGES | prostaglandin E synthase | 0.00537914 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) | 0.00537733 |
| REEP1 | receptor accessory protein 1 | 0.0053687 |
| WIPF1 | WAS/WASL interacting protein family, member 1 | 0.00536544 |
| ADA | adenosine deaminase | 0.00535854 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 | 0.00534752 |
| ATXN1 | ataxin 1 | 0.00534731 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.00534717 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.005319 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00530303 |
| TRAPPC3 | trafficking protein particle complex 3 | 0.00530265 |
| EIF3F | eukaryotic translation initiation factor 3, subunit F | 0.00530235 |
| MICB | MHC class I polypeptide-related sequence B | 0.00528776 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.00528429 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00528249 |
| RUNX1 | runt-related transcription factor 1 | 0.00527281 |
| ARF1 | ADP-ribosylation factor 1 | 0.00525303 |
| TYRP1 | tyrosinase-related protein 1 | 0.00524973 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.00524137 |
| RXRA | retinoid X receptor, alpha | 0.00523848 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00523664 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00522327 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.00520547 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00519101 |
| RPN2 | ribophorin II | 0.00519098 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.0051901 |
| KLK7 | kallikrein-related peptidase 7 | 0.00517042 |
| POGLUT2 | protein O-glucosyltransferase 2 | 0.00516577 |
| DLD | dihydrolipoamide dehydrogenase | 0.00516476 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | 0.00515835 |
| IL10RB | interleukin 10 receptor, beta | 0.00515814 |
| ITM2A | integral membrane protein 2A | 0.00515095 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.00514766 |
| SSR4 | signal sequence receptor, delta | 0.00514522 |
| PCYOX1L | prenylcysteine oxidase 1 like | 0.00514487 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | 0.00514087 |
| AFP | alpha-fetoprotein | 0.00511916 |
| HTRA1 | HtrA serine peptidase 1 | 0.00510569 |
| PRMT5 | protein arginine methyltransferase 5 | 0.00510349 |
| FBXO2 | F-box protein 2 | 0.00509414 |
| FOLR1 | folate receptor 1 (adult) | 0.00509282 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00508614 |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain | 0.0050848 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00508469 |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 | 0.00507583 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | 0.00507174 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.00506921 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa | 0.00506873 |
| GTF2H4 | general transcription factor IIH, polypeptide 4, 52kDa | 0.00506807 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 0.0050657 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.00505936 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00505409 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0231787 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0168983 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0157223 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.0144725 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0138019 |
| CD163 | CD163 molecule | -0.0137538 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.0131804 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.0130188 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.0124307 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0120169 |
| MT1M | metallothionein 1M | -0.0119242 |
| GLUL | glutamate-ammonia ligase | -0.0119202 |
| MAP7 | microtubule-associated protein 7 | -0.011732 |
| C1QB | complement component 1, q subcomponent, B chain | -0.0116901 |
| MMP12 | matrix metallopeptidase 12 | -0.0116678 |
| MAOA | monoamine oxidase A | -0.0110319 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0107933 |
| IRS2 | insulin receptor substrate 2 | -0.0107341 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0106439 |
| AREG | amphiregulin | -0.01022 |
| PLCB4 | phospholipase C, beta 4 | -0.0101722 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.0100722 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00993924 |
| MMP9 | matrix metallopeptidase 9 | -0.00992808 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00988566 |
| CD38 | CD38 molecule | -0.00979702 |
| PCDH9 | protocadherin 9 | -0.00968935 |
| EREG | epiregulin | -0.00948994 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00942186 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.00937251 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00928404 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | -0.00923439 |
| PLTP | phospholipid transfer protein | -0.00922005 |
| NUP58 | nucleoporin 58 | -0.00919362 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00912285 |
| HMGB1 | high mobility group box 1 | -0.00911681 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.00904218 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0088819 |
| TPD52L1 | tumor protein D52-like 1 | -0.00887644 |
| TGM2 | transglutaminase 2 | -0.00885951 |
| CD209 | CD209 molecule | -0.00880239 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.00877914 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00877433 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00870158 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00862662 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00859524 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.0085735 |
| EFNB2 | ephrin-B2 | -0.00845995 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00835678 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.00827523 |
| VEGFA | vascular endothelial growth factor A | -0.00827407 |
| CCP110 | centriolar coiled coil protein 110kDa | -0.00826077 |
| CPM | carboxypeptidase M | -0.0082355 |
| CTSZ | cathepsin Z | -0.00821205 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00818894 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00816979 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.0081497 |
| KLF9 | Kruppel-like factor 9 | -0.00806833 |
| TLCD3A | TLC domain containing 3A | -0.00805586 |
| ZBTB16 | zinc finger and BTB domain containing 16 | -0.00803811 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00799096 |
| NRCAM | neuronal cell adhesion molecule | -0.00796786 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.00786531 |
| KCNN3 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 | -0.00781794 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00766392 |
| INSM1 | insulinoma-associated 1 | -0.00760223 |
| KIAA0226L | KIAA0226-like | -0.00759551 |
| PCDH17 | protocadherin 17 | -0.0075905 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | -0.0075542 |
| SAP30 | Sin3A-associated protein, 30kDa | -0.0075089 |
| CCNB1 | cyclin B1 | -0.00750479 |
| CHI3L2 | chitinase 3-like 2 | -0.00748993 |
| HHEX | hematopoietically expressed homeobox | -0.00746142 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.00743359 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.00736524 |
| IPO13 | importin 13 | -0.00736191 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | -0.00733876 |
| ASPH | aspartate beta-hydroxylase | -0.00729163 |
| ACKR3 | atypical chemokine receptor 3 | -0.00724704 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00724076 |
| OPHN1 | oligophrenin 1 | -0.00722388 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0072001 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00719488 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.00717931 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.00715131 |
| SIK1 | salt-inducible kinase 1 | -0.0071447 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.0071447 |
| GALC | galactosylceramidase | -0.00714175 |
| CD320 | CD320 molecule | -0.00713211 |
| PMP22 | peripheral myelin protein 22 | -0.00712941 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.00711366 |
| MCF2L | MCF.2 cell line derived transforming sequence-like | -0.00709752 |
| PDE8B | phosphodiesterase 8B | -0.00708211 |
| PLXND1 | plexin D1 | -0.00706759 |
| TG | thyroglobulin | -0.0070339 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.007005 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.00697358 |
| TNC | tenascin C | -0.00696479 |
| INSR | insulin receptor | -0.00693701 |
| ADIRF | adipogenesis regulatory factor | -0.00693212 |
| MINK1 | misshapen-like kinase 1 | -0.0069177 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | -0.00688714 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00688689 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.00686239 |
| MT1X | metallothionein 1X | -0.00686181 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00684309 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00683173 |
| PCP4 | Purkinje cell protein 4 | -0.00681695 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00680626 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00680048 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00678539 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -0.00678028 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00676352 |
| TCF4 | transcription factor 4 | -0.00675253 |
| CHN1 | chimerin 1 | -0.00674907 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.00674659 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.00674108 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | -0.00674035 |
| FAM189A2 | family with sequence similarity 189, member A2 | -0.00672119 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00661266 |
| STX4 | syntaxin 4 | -0.00659959 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00657943 |
| RASA4 | RAS p21 protein activator 4 | -0.00657835 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.00655532 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | -0.00654044 |
| TSPYL5 | TSPY-like 5 | -0.00652556 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00648959 |
| FADS1 | fatty acid desaturase 1 | -0.00648354 |
| SDC3 | syndecan 3 | -0.00647849 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.0064531 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | -0.0064429 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -0.00644193 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00643234 |
| MGP | matrix Gla protein | -0.00642596 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | -0.00641357 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | -0.00640667 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0063844 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.00637718 |
| TMEM176B | transmembrane protein 176B | -0.0063731 |
| MARCO | macrophage receptor with collagenous structure | -0.00631857 |
| SYBU | syntabulin (syntaxin-interacting) | -0.00629489 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0062948 |
| CD44 | CD44 molecule (Indian blood group) | -0.00628917 |
| HIRA | histone cell cycle regulator | -0.00626126 |
| NNMT | nicotinamide N-methyltransferase | -0.00625781 |
| SDC2 | syndecan 2 | -0.00625677 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.00624154 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | -0.00618203 |
| CYBB | cytochrome b-245, beta polypeptide | -0.00617723 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00616396 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.00613717 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) | -0.00613539 |
| ITGA7 | integrin, alpha 7 | -0.00609162 |
| G0S2 | G0/G1 switch 2 | -0.00606262 |
| NEBL | nebulette | -0.00605459 |
| CFD | complement factor D (adipsin) | -0.00604594 |
| WDTC1 | WD and tetratricopeptide repeats 1 | -0.00602758 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00602344 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00602186 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | -0.00600476 |
| LMNA | lamin A/C | -0.00600176 |
| DCSTAMP | dendrocyte expressed seven transmembrane protein | -0.00599234 |
| FKBP5 | FK506 binding protein 5 | -0.00597465 |
| DLX5 | distal-less homeobox 5 | -0.00597041 |
| GPX2 | glutathione peroxidase 2 | -0.00596133 |
| CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 | -0.00595926 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | -0.00594316 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | -0.00592702 |
| CHGB | chromogranin B | -0.00592644 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00592514 |
| NFASC | neurofascin | -0.00590868 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -0.00590017 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 | -0.00586676 |
| SRSF10 | serine/arginine-rich splicing factor 10 | -0.00586555 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | -0.00586302 |
| SNX13 | sorting nexin 13 | -0.00586279 |
| HAUS2 | HAUS augmin-like complex, subunit 2 | -0.0058598 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.00585506 |
| KRT81 | keratin 81, type II | -0.00585292 |
| FPR3 | formyl peptide receptor 3 | -0.00585155 |
| BEX1 | brain expressed, X-linked 1 | -0.00585034 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00584437 |
| CLIP3 | CAP-GLY domain containing linker protein 3 | -0.00584115 |
| STC1 | stanniocalcin 1 | -0.00584113 |
| GABRB1 | gamma-aminobutyric acid (GABA) A receptor, beta 1 | -0.00582056 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00580889 |
| PER2 | period circadian clock 2 | -0.00580416 |
| TSPAN5 | tetraspanin 5 | -0.00579156 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | -0.00577649 |
| RIMS3 | regulating synaptic membrane exocytosis 3 | -0.00576281 |
| KBTBD2 | kelch repeat and BTB (POZ) domain containing 2 | -0.00575789 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | -0.00575529 |
| C1R | complement component 1, r subcomponent | -0.00575057 |
| NCAM1 | neural cell adhesion molecule 1 | -0.00573763 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00572679 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.00571638 |
| RTN1 | reticulon 1 | -0.00569455 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 | -0.00568801 |
| CNR1 | cannabinoid receptor 1 (brain) | -0.00567834 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | -0.00566692 |
| INSL3 | insulin-like 3 (Leydig cell) | -0.00566386 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.00565674 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00564773 |
| RDH5 | retinol dehydrogenase 5 (11-cis/9-cis) | -0.00564397 |
| VWF | von Willebrand factor | -0.00563169 |
| CP | ceruloplasmin (ferroxidase) | -0.00561589 |
| APOD | apolipoprotein D | -0.0055976 |
| MCM7 | minichromosome maintenance complex component 7 | -0.00559101 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | -0.00558218 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00558074 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | -0.00558017 |
| HSPB7 | heat shock 27kDa protein family, member 7 (cardiovascular) | -0.00557037 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase | -0.00556706 |
| ICA1 | islet cell autoantigen 1, 69kDa | -0.00556603 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | -0.00555439 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00555338 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.00555158 |
| USP47 | ubiquitin specific peptidase 47 | -0.00555027 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.00554932 |
| IL7R | interleukin 7 receptor | -0.00554843 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00554002 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 | -0.00553949 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00552615 |
| LBH | limb bud and heart development | -0.00550743 |
| NEK2 | NIMA-related kinase 2 | -0.00549906 |
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) | -0.00549834 |
| MAGEA3 | melanoma antigen family A3 | -0.00549573 |
| DSC2 | desmocollin 2 | -0.00549196 |
| ZNF12 | zinc finger protein 12 | -0.00548922 |
| RNF19B | ring finger protein 19B | -0.0054887 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00547715 |
| MED13 | mediator complex subunit 13 | -0.00547371 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.00545676 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | -0.00544146 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | -0.00543621 |
| H2AX | H2A.X variant histone | -0.00543377 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | -0.00542733 |
| DUSP8 | dual specificity phosphatase 8 | -0.00542687 |
| PRTN3 | proteinase 3 | -0.00542125 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -0.00541954 |
| CBX5 | chromobox homolog 5 | -0.0054118 |
| CRMP1 | collapsin response mediator protein 1 | -0.00540733 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00540405 |
| H1-0 | H1.0 linker histone | -0.00539689 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.00539592 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.0053958 |
| RND3 | Rho family GTPase 3 | -0.00539395 |
| DIXDC1 | DIX domain containing 1 | -0.00539154 |
