| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | fibroblast growth factor receptor 1|The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2260) |
| External Link | https://ncbi.nlm.nih.gov/gene/2260 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the FGFR1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CA2 | carbonic anhydrase II | 0.0196244 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.0177358 |
| LTF | lactotransferrin | 0.0173724 |
| DEFB1 | defensin, beta 1 | 0.0162977 |
| RGCC | regulator of cell cycle | 0.0162068 |
| ATF3 | activating transcription factor 3 | 0.0154286 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0148203 |
| SIRT3 | sirtuin 3 | 0.0132153 |
| S100A9 | S100 calcium binding protein A9 | 0.0131863 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.012997 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.0126788 |
| TPM4 | tropomyosin 4 | 0.0124934 |
| CLDN10 | claudin 10 | 0.0123387 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.01233 |
| S100P | S100 calcium binding protein P | 0.0122572 |
| ADD3 | adducin 3 (gamma) | 0.0120334 |
| MAL | mal, T-cell differentiation protein | 0.0118335 |
| FABP7 | fatty acid binding protein 7, brain | 0.0114649 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.0113531 |
| KLK6 | kallikrein-related peptidase 6 | 0.0113 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.0112006 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0110823 |
| SPRR3 | small proline-rich protein 3 | 0.0110524 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.010854 |
| HIST1H2AC | histone cluster 1, H2ac | 0.0108158 |
| BTG3 | BTG family, member 3 | 0.0107984 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.0107844 |
| S100A7 | S100 calcium binding protein A7 | 0.0107184 |
| MMD | monocyte to macrophage differentiation-associated | 0.0107019 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.0106103 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0105102 |
| NEBL | nebulette | 0.0104512 |
| ANO10 | anoctamin 10 | 0.0103617 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.010151 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.0100212 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.00997357 |
| SELL | selectin L | 0.00989408 |
| CSTA | cystatin A (stefin A) | 0.00986551 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.00976424 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00963836 |
| DAXX | death-domain associated protein | 0.00962688 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00958936 |
| MUC16 | mucin 16, cell surface associated | 0.0095393 |
| RCAN1 | regulator of calcineurin 1 | 0.00952296 |
| AZIN1 | antizyme inhibitor 1 | 0.00950771 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00947521 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00939387 |
| NCF2 | neutrophil cytosolic factor 2 | 0.00931068 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.00920996 |
| EGR2 | early growth response 2 | 0.00917425 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00913319 |
| AREG | amphiregulin | 0.00910863 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00906902 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00906597 |
| KRT13 | keratin 13, type I | 0.00904763 |
| H1-0 | H1.0 linker histone | 0.00903524 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00899215 |
| LY96 | lymphocyte antigen 96 | 0.00890462 |
| RHCG | Rh family, C glycoprotein | 0.00886598 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0088479 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00884484 |
| FOXG1 | forkhead box G1 | 0.00881851 |
| EMP1 | epithelial membrane protein 1 | 0.00879511 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00877641 |
| CHI3L2 | chitinase 3-like 2 | 0.00871346 |
| IFI44 | interferon-induced protein 44 | 0.00870882 |
| EVI2A | ecotropic viral integration site 2A | 0.00866292 |
| KLK8 | kallikrein-related peptidase 8 | 0.00862509 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00860694 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.0085873 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00858385 |
| FGG | fibrinogen gamma chain | 0.00857764 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | 0.00856419 |
| MYBPC1 | myosin binding protein C, slow type | 0.00856044 |
| THBD | thrombomodulin | 0.00850065 |
| C5AR1 | complement component 5a receptor 1 | 0.00849812 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00849258 |
| TPBG | trophoblast glycoprotein | 0.00849048 |
| KRT14 | keratin 14, type I | 0.00847804 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | 0.00846129 |
| TFRC | transferrin receptor | 0.00842976 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.00840503 |
| KYNU | kynureninase | 0.00834189 |
| IL15 | interleukin 15 | 0.0082784 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00819926 |
| LCN2 | lipocalin 2 | 0.00812824 |
| SCEL | sciellin | 0.00812572 |
| EREG | epiregulin | 0.00812051 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00809882 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00798155 |
| BEX4 | brain expressed, X-linked 4 | 0.00793531 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.0079195 |
| GDI2 | GDP dissociation inhibitor 2 | 0.00790214 |
| KRT23 | keratin 23, type I | 0.00783163 |
| MRPL19 | mitochondrial ribosomal protein L19 | 0.00782445 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00781289 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00780375 |
| STON1 | stonin 1 | 0.00778879 |
| CHMP1B | charged multivesicular body protein 1B | 0.00773099 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0077097 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00770667 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0076999 |
| POPDC3 | popeye domain containing 3 | 0.00769675 |
| VAMP5 | vesicle-associated membrane protein 5 | 0.00767136 |
| EXOC5 | exocyst complex component 5 | 0.00766049 |
| S100A8 | S100 calcium binding protein A8 | 0.00764649 |
| PLIN3 | perilipin 3 | 0.00759646 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | 0.00759521 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00755845 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00754761 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.00753465 |
| RAB13 | RAB13, member RAS oncogene family | 0.00753002 |
| AK4 | adenylate kinase 4 | 0.00752795 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | 0.00751891 |
| LYPLA1 | lysophospholipase I | 0.00750179 |
| YIPF5 | Yip1 domain family, member 5 | 0.00747651 |
| GPM6B | glycoprotein M6B | 0.00744929 |
| DOK5 | docking protein 5 | 0.00743306 |
| CD200 | CD200 molecule | 0.00742262 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.00741139 |
| ANXA1 | annexin A1 | 0.00732425 |
| KLK10 | kallikrein-related peptidase 10 | 0.00731538 |
| TP53I3 | tumor protein p53 inducible protein 3 | 0.00729598 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 0.00728445 |
| KRT17 | keratin 17, type I | 0.00726291 |
| ETHE1 | ethylmalonic encephalopathy 1 | 0.00726052 |
| MDFIC | MyoD family inhibitor domain containing | 0.00725011 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.00723316 |
| TM6SF1 | transmembrane 6 superfamily member 1 | 0.00722497 |
| MX1 | MX dynamin-like GTPase 1 | 0.00717335 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00715987 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.0071446 |
| GOLT1B | golgi transport 1B | 0.00714335 |
| KLK7 | kallikrein-related peptidase 7 | 0.00710642 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00710217 |
| CNN2 | calponin 2 | 0.00708428 |
| THY1 | Thy-1 cell surface antigen | 0.00708306 |
| CD53 | CD53 molecule | 0.00707785 |
| LHFP | lipoma HMGIC fusion partner | 0.00706093 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00705768 |
| CLIC5 | chloride intracellular channel 5 | 0.00700462 |
| EGR3 | early growth response 3 | 0.00695576 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | 0.00693421 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.00693084 |
| FZD6 | frizzled class receptor 6 | 0.0069303 |
| CFI | complement factor I | 0.00691603 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00689875 |
| PRKD3 | protein kinase D3 | 0.0068869 |
| MYO1C | myosin IC | 0.00688617 |
| PITX1 | paired-like homeodomain 1 | 0.00686324 |
| IFI44L | interferon-induced protein 44-like | 0.00685304 |
| SH3BGR | SH3 domain binding glutamate-rich protein | 0.0068488 |
| BID | BH3 interacting domain death agonist | 0.00684774 |
| TPM2 | tropomyosin 2 (beta) | 0.00683517 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00682612 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00681391 |
| YPEL5 | yippee-like 5 (Drosophila) | 0.00681052 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00680796 |
| MMP7 | matrix metallopeptidase 7 | 0.00680541 |
| HP | haptoglobin | 0.00678429 |
| PTGES | prostaglandin E synthase | 0.00676282 |
| C1ORF54 | chromosome 1 open reading frame 54 | 0.0067606 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | 0.00675259 |
| FSCN1 | fascin actin-bundling protein 1 | 0.00674606 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00674035 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | 0.00673686 |
| ANXA3 | annexin A3 | 0.00671328 |
| ABHD5 | abhydrolase domain containing 5 | 0.00668608 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.00665649 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | 0.0066433 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 0.0066419 |
| PLVAP | plasmalemma vesicle associated protein | 0.00664005 |
| DNTT | DNA nucleotidylexotransferase | 0.00663892 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.00663822 |
| PITX3 | paired-like homeodomain 3 | 0.00663351 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 | 0.0066222 |
| DAZAP2 | DAZ associated protein 2 | 0.0066098 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.00660447 |
| GPX7 | glutathione peroxidase 7 | 0.00659566 |
| FTO | fat mass and obesity associated | 0.00659305 |
| TRAM1 | translocation associated membrane protein 1 | 0.00656646 |
| SERP1 | stress-associated endoplasmic reticulum protein 1 | 0.00654893 |
| SLN | sarcolipin | 0.00653978 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.00653926 |
| CCK | cholecystokinin | 0.00652983 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.00651489 |
| IQCG | IQ motif containing G | 0.0064944 |
| CCL22 | chemokine (C-C motif) ligand 22 | 0.0064837 |
| SPRR1B | small proline-rich protein 1B | 0.00646901 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00645918 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00643146 |
| CBFB | core-binding factor, beta subunit | 0.00642879 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.00642809 |
| PLP1 | proteolipid protein 1 | 0.00642588 |
| MRPS16 | mitochondrial ribosomal protein S16 | 0.00642035 |
| PLBD1 | phospholipase B domain containing 1 | 0.00639014 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.00637364 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00636761 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00634877 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | 0.00633552 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | 0.00633278 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | 0.0063235 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00632319 |
| GOT1 | glutamic-oxaloacetic transaminase 1, soluble | 0.00631605 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | 0.00629704 |
| FOSL2 | FOS-like antigen 2 | 0.00628867 |
| ABI2 | abl-interactor 2 | 0.00628572 |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P | 0.00627409 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 0.00626673 |
| MREG | melanoregulin | 0.00626582 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 | 0.00625788 |
| IL1RN | interleukin 1 receptor antagonist | 0.00625414 |
| GPC3 | glypican 3 | 0.00625407 |
| CYB5R4 | cytochrome b5 reductase 4 | 0.00625381 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.00624854 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00623511 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00623393 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | 0.00623303 |
| H1-10 | H1.10 linker histone | 0.00623229 |
| MLF1 | myeloid leukemia factor 1 | 0.00621959 |
| ITM2C | integral membrane protein 2C | 0.00621162 |
| BAALC | brain and acute leukemia, cytoplasmic | 0.00619877 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00619433 |
| RNF167 | ring finger protein 167 | 0.00619384 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00619139 |
| RANBP9 | RAN binding protein 9 | 0.00618876 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 | 0.00617486 |
| CH25H | cholesterol 25-hydroxylase | 0.00617174 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.006165 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.00616137 |
| CRIPT | cysteine-rich PDZ-binding protein | 0.00615893 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00614498 |
| TMEM45A | transmembrane protein 45A | 0.00613466 |
| GPX1 | glutathione peroxidase 1 | 0.00611876 |
| GMFG | glia maturation factor, gamma | 0.00611805 |
| TRIM22 | tripartite motif containing 22 | 0.00610779 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00608542 |
| MRPL18 | mitochondrial ribosomal protein L18 | 0.00607097 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.00605597 |
| SYBU | syntabulin (syntaxin-interacting) | 0.006053 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.00605052 |
| IL1R2 | interleukin 1 receptor, type II | 0.00604974 |
| OLFML2B | olfactomedin-like 2B | 0.00604958 |
| HOMER1 | homer scaffolding protein 1 | 0.00604034 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 0.00603851 |
| RNASET2 | ribonuclease T2 | 0.00603125 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00602362 |
| E2F5 | E2F transcription factor 5, p130-binding | 0.00602232 |
| IL6ST | interleukin 6 signal transducer | 0.00601885 |
| GSTP1 | glutathione S-transferase pi 1 | 0.00601044 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | -0.0202256 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0188844 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.0162755 |
| TPSAB1 | tryptase alpha/beta 1 | -0.012308 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0116736 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0112117 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.0111047 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.0108008 |
| NOTCH2NL | notch 2 N-terminal like | -0.0107618 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.0107446 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.0107195 |
| TFF1 | trefoil factor 1 | -0.0106999 |
| APOD | apolipoprotein D | -0.0104694 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.010366 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.0103615 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | -0.0101235 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.010035 |
| AGR2 | anterior gradient 2 | -0.0100271 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00969008 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00965818 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | -0.00935309 |
| LONP2 | lon peptidase 2, peroxisomal | -0.00926033 |
| MAOA | monoamine oxidase A | -0.00914231 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.0091022 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00905038 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | -0.00897495 |
| DKFZP586I1420 | uncharacterized protein DKFZp586I1420 | -0.00891908 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.00890399 |
| STK26 | serine/threonine protein kinase 26 | -0.00881543 |
| PMP22 | peripheral myelin protein 22 | -0.00876911 |
| BCHE | butyrylcholinesterase | -0.00862991 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.00852606 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0085162 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0084838 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.00843229 |
| GOLGA8H | golgin A8 family, member H | -0.00839065 |
| PRKCZ | protein kinase C, zeta | -0.00837671 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.00837532 |
| CDC20 | cell division cycle 20 | -0.00831791 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.00829792 |
| EML3 | echinoderm microtubule associated protein like 3 | -0.0082834 |
| WFDC1 | WAP four-disulfide core domain 1 | -0.00822229 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | -0.00821138 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00820715 |
| MTCL1 | microtubule crosslinking factor 1 | -0.00819715 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00819651 |
| GATA6 | GATA binding protein 6 | -0.00817267 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | -0.00811718 |
| GUSB | glucuronidase, beta | -0.00807109 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00805019 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00800304 |
| SFTPB | surfactant protein B | -0.00799572 |
| TOX3 | TOX high mobility group box family member 3 | -0.00796139 |
| SNX1 | sorting nexin 1 | -0.00795135 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00794568 |
| GGT1 | gamma-glutamyltransferase 1 | -0.00793638 |
| FASN | fatty acid synthase | -0.00792943 |
| TXNIP | thioredoxin interacting protein | -0.00790621 |
| NVL | nuclear VCP-like | -0.00790376 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00789631 |
| ADCY9 | adenylate cyclase 9 | -0.00788783 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00787769 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.00783242 |
| PCP4 | Purkinje cell protein 4 | -0.00780122 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.00770226 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | -0.00766367 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00764084 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.00763608 |
| MAMLD1 | mastermind-like domain containing 1 | -0.00759759 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.00755971 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00751336 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00749819 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | -0.00743193 |
| USP48 | ubiquitin specific peptidase 48 | -0.00742386 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.00742169 |
| NOTCH2 | notch 2 | -0.00741427 |
| CTBP2 | C-terminal binding protein 2 | -0.00740845 |
| PRR11 | proline rich 11 | -0.00739197 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0073797 |
| LIPG | lipase, endothelial | -0.0073142 |
| PILRB | paired immunoglobin-like type 2 receptor beta | -0.00725911 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00724146 |
| BRD2 | bromodomain containing 2 | -0.00721726 |
| RUFY3 | RUN and FYVE domain containing 3 | -0.00720728 |
| NOP53 | NOP53 ribosome biogenesis factor | -0.00719881 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00713638 |
| XYLT1 | xylosyltransferase I | -0.00709874 |
| GOLGA8A | golgin A8 family, member A | -0.00704829 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00704646 |
| HOXC6 | homeobox C6 | -0.00704208 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 | -0.00704204 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00703435 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -0.00701743 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00696491 |
| ZNF160 | zinc finger protein 160 | -0.0069633 |
| OLFM4 | olfactomedin 4 | -0.00695526 |
| DCLK1 | doublecortin-like kinase 1 | -0.00695234 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.006918 |
| SAFB2 | scaffold attachment factor B2 | -0.00691669 |
| NUP210 | nucleoporin 210kDa | -0.00690224 |
| REG3A | regenerating islet-derived 3 alpha | -0.00687007 |
| SCAF4 | SR-related CTD-associated factor 4 | -0.00686426 |
| PRPF4B | pre-mRNA processing factor 4B | -0.00686296 |
| RXRA | retinoid X receptor, alpha | -0.00685881 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.00685036 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00684615 |
| TBL1X | transducin (beta)-like 1X-linked | -0.00684078 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | -0.00683192 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00680957 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | -0.00679537 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 | -0.00676875 |
| NAA40 | N(alpha)-acetyltransferase 40, NatD catalytic subunit | -0.00672334 |
| NXN | nucleoredoxin | -0.0067232 |
| NOTCH1 | notch 1 | -0.00669907 |
| KLC2 | kinesin light chain 2 | -0.00669202 |
| HIRA | histone cell cycle regulator | -0.00666807 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00666651 |
| SMTN | smoothelin | -0.0066455 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | -0.00664145 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | -0.00663934 |
| PRC1 | protein regulator of cytokinesis 1 | -0.00663796 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -0.00661955 |
| EPCAM | epithelial cell adhesion molecule | -0.00657679 |
| FBXW12 | F-box and WD repeat domain containing 12 | -0.00656054 |
| FAM13B | family with sequence similarity 13, member B | -0.00649984 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.00646864 |
| RRBP1 | ribosome binding protein 1 | -0.00644967 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.00643428 |
| WASL | Wiskott-Aldrich syndrome-like | -0.00639618 |
| NSUN5P1 | NOP2/Sun domain family, member 5 pseudogene 1 | -0.00635054 |
| LRP5 | low density lipoprotein receptor-related protein 5 | -0.00632987 |
| HDC | histidine decarboxylase | -0.00631355 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.006302 |
| CALD1 | caldesmon 1 | -0.00626648 |
| BBX | bobby sox homolog (Drosophila) | -0.00625816 |
| TENM1 | teneurin transmembrane protein 1 | -0.0062254 |
| PFKL | phosphofructokinase, liver | -0.00617114 |
| MMP1 | matrix metallopeptidase 1 | -0.0061625 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00614606 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta | -0.00614478 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.00612661 |
| NPR3 | natriuretic peptide receptor 3 | -0.00611961 |
| ANAPC2 | anaphase promoting complex subunit 2 | -0.00611802 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.0061171 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | -0.00610477 |
| HOXC10 | homeobox C10 | -0.00609686 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00607869 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.00607117 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00606629 |
| CHN2 | chimerin 2 | -0.00606244 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | -0.00606212 |
| ING3 | inhibitor of growth family, member 3 | -0.00605682 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00604836 |
| REPIN1 | replication initiator 1 | -0.0060387 |
| CLCA1 | chloride channel accessory 1 | -0.00602327 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00601503 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 | -0.00600879 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00599609 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | -0.0059897 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.00598851 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.00594834 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.00594151 |
| CCNL2 | cyclin L2 | -0.00594047 |
| INSM1 | insulinoma-associated 1 | -0.00592616 |
| GSE1 | Gse1 coiled-coil protein | -0.005908 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | -0.00590673 |
| SDF4 | stromal cell derived factor 4 | -0.00588802 |
| CDK13 | cyclin-dependent kinase 13 | -0.00588572 |
| REG1B | regenerating islet-derived 1 beta | -0.00587741 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.00587685 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.00586555 |
| PLA1A | phospholipase A1 member A | -0.00584385 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | -0.00584234 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | -0.00584073 |
| ZNF721 | zinc finger protein 721 | -0.00582443 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | -0.00578692 |
| PDGFC | platelet derived growth factor C | -0.00577261 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00577249 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | -0.00577241 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.00576976 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | -0.00576427 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0057506 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.00573652 |
| EFHD2 | EF-hand domain family, member D2 | -0.00573268 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00573205 |
| MYLIP | myosin regulatory light chain interacting protein | -0.00572237 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00571877 |
| GRAMD4 | GRAM domain containing 4 | -0.00571743 |
| TXLNA | taxilin alpha | -0.00569165 |
| POSTN | periostin, osteoblast specific factor | -0.00568898 |
| TOB2 | transducer of ERBB2, 2 | -0.00568776 |
| HIP1R | huntingtin interacting protein 1 related | -0.00567821 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.00567375 |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 | -0.00567074 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00566674 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -0.00566252 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.00563692 |
| MLPH | melanophilin | -0.00562603 |
| STX3 | syntaxin 3 | -0.00562176 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00561891 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta | -0.00561129 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.00561092 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | -0.00560914 |
| CMTR1 | cap methyltransferase 1 | -0.00560128 |
| TBX3 | T-box 3 | -0.00559956 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00559407 |
| CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 | -0.00558926 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00558535 |
| KLF3-AS1 | KLF3 antisense RNA 1 | -0.00558253 |
| CFP | complement factor properdin | -0.00558242 |
| GATA2 | GATA binding protein 2 | -0.0055636 |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 | -0.00556033 |
| CRHBP | corticotropin releasing hormone binding protein | -0.00553227 |
| FAM50A | family with sequence similarity 50, member A | -0.00553081 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00551729 |
| STK25 | serine/threonine kinase 25 | -0.00551144 |
| ESR1 | estrogen receptor 1 | -0.00550017 |
| TSC2 | tuberous sclerosis 2 | -0.00549973 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | -0.00549759 |
| MATN2 | matrilin 2 | -0.00548788 |
| JUND | jun D proto-oncogene | -0.00548662 |
| C6 | complement component 6 | -0.00548599 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | -0.00547538 |
| TPCN1 | two pore segment channel 1 | -0.00547515 |
| GGTLC1 | gamma-glutamyltransferase light chain 1 | -0.00547157 |
| TRIM37 | tripartite motif containing 37 | -0.00545763 |
| SUGP2 | SURP and G patch domain containing 2 | -0.0054518 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) | -0.00545098 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.00545068 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.00544954 |
| NEUROD1 | neuronal differentiation 1 | -0.0054314 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.00542848 |
| CRY1 | cryptochrome circadian clock 1 | -0.00542629 |
| CLDN3 | claudin 3 | -0.00542229 |
| ATP8B4 | ATPase, class I, type 8B, member 4 | -0.00541156 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.00540608 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.00540169 |
| SRSF10 | serine/arginine-rich splicing factor 10 | -0.00539975 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | -0.00539507 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -0.00538339 |
| IPO9 | importin 9 | -0.0053781 |
| TSPAN12 | tetraspanin 12 | -0.0053742 |
| SDC3 | syndecan 3 | -0.00536413 |
| HOPX | HOP homeobox | -0.0053578 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | -0.00534777 |
| PLD3 | phospholipase D family, member 3 | -0.00534462 |
| SMAD7 | SMAD family member 7 | -0.00534447 |
| MTA1 | metastasis associated 1 | -0.00534201 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | -0.005341 |
