| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | fibroblast growth factor receptor 3|This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Jul 2009] (NCBI Entrez Gene Database, 2261) |
| External Link | https://ncbi.nlm.nih.gov/gene/2261 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the FGFR3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.0155256 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0135341 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0127686 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.0114276 |
| KLK10 | kallikrein-related peptidase 10 | 0.0113782 |
| GNAS | GNAS complex locus | 0.0107098 |
| RGCC | regulator of cell cycle | 0.010395 |
| PRAME | preferentially expressed antigen in melanoma | 0.0103076 |
| TRIM29 | tripartite motif containing 29 | 0.0102569 |
| ANXA1 | annexin A1 | 0.0100551 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00997906 |
| KLK11 | kallikrein-related peptidase 11 | 0.00989862 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0098585 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00975065 |
| RRAGA | Ras-related GTP binding A | 0.00974935 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00967621 |
| ABLIM1 | actin binding LIM protein 1 | 0.0092213 |
| DAXX | death-domain associated protein | 0.00920251 |
| DEFB1 | defensin, beta 1 | 0.00897131 |
| ANXA3 | annexin A3 | 0.00884311 |
| MYBPC1 | myosin binding protein C, slow type | 0.00884 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 0.0088254 |
| MUC16 | mucin 16, cell surface associated | 0.00871695 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00859045 |
| SPRR3 | small proline-rich protein 3 | 0.0085623 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00844813 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00839461 |
| STATH | statherin | 0.00833206 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00831713 |
| PITX3 | paired-like homeodomain 3 | 0.00824626 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00823654 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.00819804 |
| TPM2 | tropomyosin 2 (beta) | 0.00811027 |
| KRT5 | keratin 5, type II | 0.00781288 |
| UPK1B | uroplakin 1B | 0.00776084 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0077112 |
| OXTR | oxytocin receptor | 0.0077028 |
| FOXG1 | forkhead box G1 | 0.00752623 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00748299 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00745038 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00738986 |
| MBD2 | methyl-CpG binding domain protein 2 | 0.00724171 |
| CLDN10 | claudin 10 | 0.00723243 |
| ZNF395 | zinc finger protein 395 | 0.00720843 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00720198 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00709294 |
| IK | IK cytokine, down-regulator of HLA II | 0.0070848 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 0.00703168 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00700889 |
| PDE8B | phosphodiesterase 8B | 0.00700234 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00698242 |
| SHCBP1 | SHC SH2-domain binding protein 1 | 0.00697146 |
| SYNM | synemin, intermediate filament protein | 0.00696835 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.00694229 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.00691911 |
| CHEK2 | checkpoint kinase 2 | 0.00689846 |
| RPL14 | ribosomal protein L14 | 0.00689092 |
| MAL | mal, T-cell differentiation protein | 0.00688292 |
| KRT23 | keratin 23, type I | 0.00687667 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00686894 |
| PDLIM1 | PDZ and LIM domain 1 | 0.00683813 |
| WWC1 | WW and C2 domain containing 1 | 0.00683747 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00678586 |
| GRAMD2B | GRAM domain containing 2B | 0.00676209 |
| ANGPT2 | angiopoietin 2 | 0.00673739 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.00670231 |
| IL6ST | interleukin 6 signal transducer | 0.00669458 |
| TNNC1 | troponin C type 1 (slow) | 0.00664436 |
| KRT17 | keratin 17, type I | 0.00663535 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00662147 |
| HOMER1 | homer scaffolding protein 1 | 0.00661897 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.00659662 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00658711 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00653837 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.00651706 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00650619 |
| S100A9 | S100 calcium binding protein A9 | 0.0064748 |
| PRKAA1 | protein kinase, AMP-activated, alpha 1 catalytic subunit | 0.00645587 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00644045 |
| KRT13 | keratin 13, type I | 0.00640728 |
| RBM34 | RNA binding motif protein 34 | 0.00638468 |
| TKTL1 | transketolase-like 1 | 0.00636025 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00635544 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00633686 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00632907 |
| BTG3 | BTG family, member 3 | 0.00631372 |
| MRPS16 | mitochondrial ribosomal protein S16 | 0.00629718 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00629605 |
| COG5 | component of oligomeric golgi complex 5 | 0.00625286 |
| ITPKB | inositol-trisphosphate 3-kinase B | 0.00625095 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.00622103 |
| TPX2 | TPX2, microtubule-associated | 0.00618671 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00616658 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.00616067 |
| STOM | stomatin | 0.00615517 |
| C14ORF132 | chromosome 14 open reading frame 132 | 0.00612254 |
| PRSS21 | protease, serine, 21 (testisin) | 0.00610957 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.00609748 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00609574 |
| ATP5PD | ATP synthase peripheral stalk subunit d | 0.00609545 |
| RHCG | Rh family, C glycoprotein | 0.00609342 |
| DOK5 | docking protein 5 | 0.00609233 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00607971 |
| KRT81 | keratin 81, type II | 0.00607831 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 0.00607662 |
| MYL6B | myosin, light chain 6B, alkali, smooth muscle and non-muscle | 0.00605619 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00605551 |
| MT1F | metallothionein 1F | 0.00605266 |
| NEBL | nebulette | 0.00603638 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.00603144 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 0.00601643 |
| MT1X | metallothionein 1X | 0.00601473 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.00601026 |
| SCEL | sciellin | 0.0059806 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00597212 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | 0.0059598 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00595069 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.00594101 |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 | 0.00593128 |
| RNASET2 | ribonuclease T2 | 0.00592072 |
| AREG | amphiregulin | 0.00591373 |
| EXOC5 | exocyst complex component 5 | 0.00585682 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | 0.00584879 |
| CHEK1 | checkpoint kinase 1 | 0.00584792 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0058414 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00583523 |
| FKBP5 | FK506 binding protein 5 | 0.0058332 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00583151 |
| DIO2 | deiodinase, iodothyronine, type II | 0.00581208 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.00580196 |
| MICB | MHC class I polypeptide-related sequence B | 0.00580193 |
| ARG1 | arginase 1 | 0.00579192 |
| HAL | histidine ammonia-lyase | 0.00577533 |
| RRAGD | Ras-related GTP binding D | 0.00575042 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00574625 |
| VWF | von Willebrand factor | 0.00574344 |
| YBX3 | Y box binding protein 3 | 0.00574169 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.00574098 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00573699 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.00573682 |
| GABRB1 | gamma-aminobutyric acid (GABA) A receptor, beta 1 | 0.00572428 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.00572192 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00571563 |
| MMP10 | matrix metallopeptidase 10 | 0.00568275 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00567611 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00565418 |
| MT1G | metallothionein 1G | 0.0056297 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | 0.00560149 |
| MMP7 | matrix metallopeptidase 7 | 0.00560064 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00557683 |
| VDAC2 | voltage-dependent anion channel 2 | 0.00557313 |
| GOT1 | glutamic-oxaloacetic transaminase 1, soluble | 0.00556472 |
| MRPL18 | mitochondrial ribosomal protein L18 | 0.0055628 |
| IQCK | IQ motif containing K | 0.00555611 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 0.00555202 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.00550796 |
| FABP7 | fatty acid binding protein 7, brain | 0.0055064 |
| ITGA6 | integrin, alpha 6 | 0.00549926 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0054971 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00548764 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00548605 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.005466 |
| CHN1 | chimerin 1 | 0.00544392 |
| ARG2 | arginase 2 | 0.00543762 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | 0.00541835 |
| MVP | major vault protein | 0.00541449 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00540656 |
| EMX2 | empty spiracles homeobox 2 | 0.00540244 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | 0.00539683 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.00539414 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.00537545 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00533615 |
| IRS2 | insulin receptor substrate 2 | 0.00533151 |
| H1-2 | H1.2 linker histone, cluster member | 0.00533103 |
| LINC00623 | long intergenic non-protein coding RNA 623 | 0.00530646 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.00529335 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00528905 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.00528771 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.00527005 |
| DAZAP2 | DAZ associated protein 2 | 0.0052596 |
| TPM3 | tropomyosin 3 | 0.00523988 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | 0.0052278 |
| TPBG | trophoblast glycoprotein | 0.00520891 |
| ERP44 | endoplasmic reticulum protein 44 | 0.00520822 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 | 0.005201 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.00519636 |
| ELANE | elastase, neutrophil expressed | 0.00518575 |
| FOLR1 | folate receptor 1 (adult) | 0.00517911 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.0051725 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0051555 |
| TFDP1 | transcription factor Dp-1 | 0.00515197 |
| NUP85 | nucleoporin 85kDa | 0.00514344 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.00512564 |
| PNMA8A | PNMA family member 8A | 0.00512186 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.00509361 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | 0.00509275 |
| GDI2 | GDP dissociation inhibitor 2 | 0.00509236 |
| CHPT1 | choline phosphotransferase 1 | 0.00508475 |
| TUBA4A | tubulin, alpha 4a | 0.00507 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00506067 |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 | 0.00505743 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.00505226 |
| MED6 | mediator complex subunit 6 | 0.0050413 |
| ACTA1 | actin, alpha 1, skeletal muscle | 0.00503882 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.00503154 |
| FBXO11 | F-box protein 11 | 0.0049925 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00499185 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00499029 |
| IFI44 | interferon-induced protein 44 | 0.00499017 |
| ZNF165 | zinc finger protein 165 | 0.00498869 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0049818 |
| AQP4 | aquaporin 4 | 0.00496823 |
| C3 | complement component 3 | 0.00495389 |
| CUEDC2 | CUE domain containing 2 | 0.00495298 |
| PRKCA | protein kinase C, alpha | 0.00494897 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.00493451 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.00493034 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00492793 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00489392 |
| MDH1 | malate dehydrogenase 1, NAD (soluble) | 0.00488857 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 | 0.00487469 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0048743 |
| UBAP2 | ubiquitin associated protein 2 | 0.00487341 |
| MEIS1 | Meis homeobox 1 | 0.00487109 |
| ARL3 | ADP-ribosylation factor-like 3 | 0.00486781 |
| CRYAB | crystallin, alpha B | 0.00485928 |
| NEU1 | sialidase 1 (lysosomal sialidase) | 0.00485161 |
| PLK1 | polo-like kinase 1 | 0.00484489 |
| SP100 | SP100 nuclear antigen | 0.00484281 |
| IFI44L | interferon-induced protein 44-like | 0.00482413 |
| MPO | myeloperoxidase | 0.00482366 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.00482047 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00480887 |
| LOX | lysyl oxidase | 0.0048028 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.00480147 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00480125 |
| NXN | nucleoredoxin | 0.00480099 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00480029 |
| RANBP9 | RAN binding protein 9 | 0.0047969 |
| ERGIC2 | ERGIC and golgi 2 | 0.0047955 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.0047912 |
| KLHL41 | kelch-like family member 41 | 0.00478494 |
| WAPL | WAPL cohesin release factor | 0.0047792 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.00477218 |
| MMP8 | matrix metallopeptidase 8 | 0.0047606 |
| GRAMD1C | GRAM domain containing 1C | 0.00475805 |
| TMEM243 | transmembrane protein 243, mitochondrial | 0.00474467 |
| WDR76 | WD repeat domain 76 | 0.00474446 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | 0.00473588 |
| JADE2 | jade family PHD finger 2 | 0.00473448 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.0127058 |
| FRZB | frizzled-related protein | -0.012704 |
| FGL2 | fibrinogen-like 2 | -0.0125664 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0122859 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.0117387 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.0109692 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0108561 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.0107406 |
| AGR2 | anterior gradient 2 | -0.0102658 |
| TCTA | T-cell leukemia translocation altered | -0.0102229 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.0101885 |
| AHR | aryl hydrocarbon receptor | -0.00979398 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00960947 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00959261 |
| RTN1 | reticulon 1 | -0.00955697 |
| ASPN | asporin | -0.00932488 |
| CD8A | CD8a molecule | -0.00930697 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00909381 |
| PMP22 | peripheral myelin protein 22 | -0.00893203 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | -0.00890736 |
| AEBP1 | AE binding protein 1 | -0.00889709 |
| JAG1 | jagged 1 | -0.00888634 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00884064 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00874036 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00866803 |
| TAGLN | transgelin | -0.00856339 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -0.00855652 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00852503 |
| PRF1 | perforin 1 (pore forming protein) | -0.00849627 |
| RCAN2 | regulator of calcineurin 2 | -0.00845429 |
| GZMK | granzyme K (granzyme 3; tryptase II) | -0.0084394 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | -0.00839892 |
| TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) | -0.00836159 |
| GLS | glutaminase | -0.00828478 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.00823807 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | -0.00819907 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00816328 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.0081383 |
| ELN | elastin | -0.00811637 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -0.00810262 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.00810229 |
| GOLGA8H | golgin A8 family, member H | -0.00803228 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | -0.00793101 |
| NVL | nuclear VCP-like | -0.00792953 |
| NKG7 | natural killer cell granule protein 7 | -0.00790778 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00783871 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00783225 |
| PTK2B | protein tyrosine kinase 2 beta | -0.00782167 |
| DCLK1 | doublecortin-like kinase 1 | -0.00780945 |
| RAPSN | receptor-associated protein of the synapse | -0.0077966 |
| MLPH | melanophilin | -0.00777465 |
| PLN | phospholamban | -0.00774746 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | -0.00773746 |
| GRAMD4 | GRAM domain containing 4 | -0.00771649 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.00764726 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.00753157 |
| DCN | decorin | -0.0075147 |
| NELL2 | NEL-like 2 (chicken) | -0.00749655 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00740917 |
| CLEC7A | C-type lectin domain family 7, member A | -0.00740473 |
| METRN | meteorin, glial cell differentiation regulator | -0.0073779 |
| LRRC15 | leucine rich repeat containing 15 | -0.0073513 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00731959 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.00728065 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0072023 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | -0.00720211 |
| TMEM176B | transmembrane protein 176B | -0.00719422 |
| TYMP | thymidine phosphorylase | -0.00716624 |
| SELENBP1 | selenium binding protein 1 | -0.0071324 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00712782 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.00711604 |
| TRIB2 | tribbles pseudokinase 2 | -0.00711095 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00705906 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.00700774 |
| PDHX | pyruvate dehydrogenase complex, component X | -0.00698327 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00697601 |
| POSTN | periostin, osteoblast specific factor | -0.00696835 |
| SCG5 | secretogranin V | -0.00685275 |
| FBLN1 | fibulin 1 | -0.00680848 |
| CTSH | cathepsin H | -0.00677923 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00675088 |
| PLXNC1 | plexin C1 | -0.00675051 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | -0.00669772 |
| TOX3 | TOX high mobility group box family member 3 | -0.00665925 |
| MFAP2 | microfibrillar-associated protein 2 | -0.00664332 |
| TARP | TCR gamma alternate reading frame protein | -0.00664311 |
| LST1 | leukocyte specific transcript 1 | -0.00657364 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0065476 |
| AIM2 | absent in melanoma 2 | -0.00651025 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.0064924 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00647911 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00646685 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | -0.00646252 |
| COMP | cartilage oligomeric matrix protein | -0.00642393 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00641059 |
| CD300A | CD300a molecule | -0.00640365 |
| FGF13 | fibroblast growth factor 13 | -0.00639099 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00638275 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00634695 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 | -0.0063207 |
| CHRDL1 | chordin-like 1 | -0.00631134 |
| CST3 | cystatin C | -0.0062878 |
| PFDN4 | prefoldin subunit 4 | -0.00628304 |
| MYO1F | myosin IF | -0.00627176 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | -0.00627098 |
| EFHD2 | EF-hand domain family, member D2 | -0.00626503 |
| FASN | fatty acid synthase | -0.00626034 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | -0.00625992 |
| FBXO2 | F-box protein 2 | -0.0062363 |
| THBS2 | thrombospondin 2 | -0.00623604 |
| ATP13A3 | ATPase type 13A3 | -0.00621948 |
| TSPAN13 | tetraspanin 13 | -0.00621135 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00620383 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00614987 |
| EGR2 | early growth response 2 | -0.00614757 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00614219 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00613653 |
| EML3 | echinoderm microtubule associated protein like 3 | -0.00607502 |
| DSE | dermatan sulfate epimerase | -0.00607174 |
| COL9A2 | collagen, type IX, alpha 2 | -0.00605643 |
| G0S2 | G0/G1 switch 2 | -0.006046 |
| PLD3 | phospholipase D family, member 3 | -0.00600662 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00598751 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00594772 |
| CLEC4A | C-type lectin domain family 4, member A | -0.00593936 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 | -0.00590954 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00590618 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00589254 |
| NDNF | neuron-derived neurotrophic factor | -0.00587578 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.00587321 |
| BGN | biglycan | -0.00584733 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.00581679 |
| RNF19B | ring finger protein 19B | -0.00581639 |
| GATA6 | GATA binding protein 6 | -0.00580716 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.00580715 |
| GCH1 | GTP cyclohydrolase 1 | -0.00580691 |
| CEL | carboxyl ester lipase | -0.0057954 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | -0.00578535 |
| C3ORF52 | chromosome 3 open reading frame 52 | -0.00577088 |
| APOC1 | apolipoprotein C-I | -0.00574571 |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 | -0.00572841 |
| MCOLN1 | mucolipin 1 | -0.00571969 |
| NID2 | nidogen 2 (osteonidogen) | -0.00571695 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | -0.00571667 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00569477 |
| COL10A1 | collagen, type X, alpha 1 | -0.00569476 |
| SMAD7 | SMAD family member 7 | -0.00566648 |
| COL3A1 | collagen, type III, alpha 1 | -0.00563899 |
| SERINC5 | serine incorporator 5 | -0.00563845 |
| BAHCC1 | BAH domain and coiled-coil containing 1 | -0.0056301 |
| SC5D | sterol-C5-desaturase | -0.00561118 |
| GNLY | granulysin | -0.00560842 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | -0.00560116 |
| CDC34 | cell division cycle 34 | -0.00559665 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00559046 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00558826 |
| ADCY7 | adenylate cyclase 7 | -0.00557582 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00557101 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | -0.00556638 |
| CD320 | CD320 molecule | -0.00556335 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00556024 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | -0.00552811 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | -0.00552718 |
| DHDDS | dehydrodolichyl diphosphate synthase | -0.00552376 |
| CTSK | cathepsin K | -0.00551761 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.00551574 |
| EPS15 | epidermal growth factor receptor pathway substrate 15 | -0.00549118 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.005489 |
| ANGEL2 | angel homolog 2 (Drosophila) | -0.00547804 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00546512 |
| GAL | galanin/GMAP prepropeptide | -0.00546364 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.00545563 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00543936 |
| LSR | lipolysis stimulated lipoprotein receptor | -0.00543526 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | -0.00543265 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.00541096 |
| CCR2 | chemokine (C-C motif) receptor 2 | -0.00540905 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00539863 |
| AURKB | aurora kinase B | -0.00539257 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.00538669 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -0.00537903 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00537793 |
| ZNF518A | zinc finger protein 518A | -0.00535928 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | -0.00535807 |
| DMXL1 | Dmx-like 1 | -0.00535543 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00535001 |
| LOXL1 | lysyl oxidase-like 1 | -0.00533792 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.00532037 |
| RUFY3 | RUN and FYVE domain containing 3 | -0.00529809 |
| TSPAN15 | tetraspanin 15 | -0.00529073 |
| CD99 | CD99 molecule | -0.00527885 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00527388 |
| SNX10 | sorting nexin 10 | -0.00527214 |
| PLXNB2 | plexin B2 | -0.00526851 |
| PTN | pleiotrophin | -0.00525209 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 | -0.00525019 |
| ERLIN2 | ER lipid raft associated 2 | -0.00524754 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00524467 |
| BEX1 | brain expressed, X-linked 1 | -0.00524155 |
| CALCA | calcitonin-related polypeptide alpha | -0.00523062 |
| IL7R | interleukin 7 receptor | -0.00521503 |
| P2RX1 | purinergic receptor P2X, ligand gated ion channel, 1 | -0.00521121 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.00520905 |
| RGS16 | regulator of G-protein signaling 16 | -0.00520159 |
| IL2RB | interleukin 2 receptor, beta | -0.0052 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.00519358 |
| INHBA | inhibin, beta A | -0.00518079 |
| GEM | GTP binding protein overexpressed in skeletal muscle | -0.00516782 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | -0.00516556 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.00516145 |
| COL6A3 | collagen, type VI, alpha 3 | -0.00515479 |
| CCN3 | cellular communication network factor 3 | -0.00513922 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.00513666 |
| BTBD2 | BTB (POZ) domain containing 2 | -0.00513443 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00513258 |
| CES1 | carboxylesterase 1 | -0.00512834 |
| ITGA8 | integrin, alpha 8 | -0.00512743 |
| MARCKSL1 | MARCKS-like 1 | -0.00512717 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.00510658 |
| CBR4 | carbonyl reductase 4 | -0.00510575 |
| LAT2 | linker for activation of T cells family, member 2 | -0.00510124 |
| DICER1 | dicer 1, ribonuclease type III | -0.00509909 |
| CCNA2 | cyclin A2 | -0.00508959 |
| THAP12 | THAP domain containing 12 | -0.00506978 |
| PKN2 | protein kinase N2 | -0.00506966 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | -0.00506527 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00505569 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.0050538 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | -0.00503916 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00502971 |
| TES | testin LIM domain protein | -0.00502763 |
| PWWP3A | PWWP domain containing 3A, DNA repair factor | -0.0050263 |
| MMP1 | matrix metallopeptidase 1 | -0.0050241 |
| ADIRF | adipogenesis regulatory factor | -0.00499362 |
| FAAH | fatty acid amide hydrolase | -0.00498949 |
| BRD4 | bromodomain containing 4 | -0.00498283 |
| EVI5 | ecotropic viral integration site 5 | -0.00497356 |
| SUCO | SUN domain containing ossification factor | -0.00497154 |
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | -0.00496764 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.00495174 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.00494769 |
| MXRA5 | matrix-remodelling associated 5 | -0.00494095 |
| CD46 | CD46 molecule, complement regulatory protein | -0.00493654 |
| C11ORF71 | chromosome 11 open reading frame 71 | -0.00491694 |
| MZB1 | marginal zone B and B1 cell-specific protein | -0.0049168 |
| ANAPC2 | anaphase promoting complex subunit 2 | -0.00490694 |
| CAPN1 | calpain 1, (mu/I) large subunit | -0.00489041 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00488033 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 | -0.00487465 |
