| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | fibroblast growth factor receptor-like 1|The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 53834) |
| External Link | https://ncbi.nlm.nih.gov/gene/53834 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the FGFRL1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TCTA | T-cell leukemia translocation altered | 0.0126979 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0123755 |
| ZIC1 | Zic family member 1 | 0.011913 |
| MAP7 | microtubule-associated protein 7 | 0.0118074 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.0108297 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.0106569 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0106544 |
| DST | dystonin | 0.010182 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0100627 |
| CADM1 | cell adhesion molecule 1 | 0.00961439 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | 0.00960382 |
| TPD52 | tumor protein D52 | 0.0095712 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0094943 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.00942799 |
| SST | somatostatin | 0.00931879 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.00924863 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00905005 |
| REEP1 | receptor accessory protein 1 | 0.00887959 |
| KLF6 | Kruppel-like factor 6 | 0.00867579 |
| TNNC1 | troponin C type 1 (slow) | 0.00866275 |
| RET | ret proto-oncogene | 0.00864074 |
| CNTN1 | contactin 1 | 0.00851585 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.00851572 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00850519 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.00847477 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00837892 |
| GCG | glucagon | 0.0083564 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.00829911 |
| XIC | X chromosome inactivation center | 0.00824952 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.00821238 |
| PLP1 | proteolipid protein 1 | 0.00817691 |
| CAB39 | calcium binding protein 39 | 0.00810526 |
| KLF9 | Kruppel-like factor 9 | 0.00807037 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | 0.00801365 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.00798899 |
| MFAP5 | microfibrillar associated protein 5 | 0.00798613 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.00794159 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0079183 |
| CRYAB | crystallin, alpha B | 0.00784315 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.00770386 |
| EXPH5 | exophilin 5 | 0.00764795 |
| CAPN3 | calpain 3, (p94) | 0.00764616 |
| PEG10 | paternally expressed 10 | 0.00764021 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.00760523 |
| ABAT | 4-aminobutyrate aminotransferase | 0.00758216 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.00745956 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00743323 |
| FRS2 | fibroblast growth factor receptor substrate 2 | 0.00742435 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.00737113 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.00733381 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.00731505 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00731157 |
| GLS | glutaminase | 0.00731084 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00727739 |
| PCDH17 | protocadherin 17 | 0.00725081 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.00723857 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00723701 |
| DAPK1 | death-associated protein kinase 1 | 0.00723554 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.00722452 |
| MEN1 | multiple endocrine neoplasia I | 0.00720276 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.00719872 |
| MRPS30 | mitochondrial ribosomal protein S30 | 0.00719518 |
| WASL | Wiskott-Aldrich syndrome-like | 0.00718998 |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.00712446 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.00711082 |
| RC3H2 | ring finger and CCCH-type domains 2 | 0.0070796 |
| AK1 | adenylate kinase 1 | 0.00703752 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0070108 |
| NFASC | neurofascin | 0.00698482 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 0.00696073 |
| CLIC5 | chloride intracellular channel 5 | 0.00694225 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | 0.00693424 |
| ZG16 | zymogen granule protein 16 | 0.00687356 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.00686942 |
| MCL1 | myeloid cell leukemia 1 | 0.00686694 |
| TTN | titin | 0.00681542 |
| RCAN2 | regulator of calcineurin 2 | 0.00681075 |
| MT1M | metallothionein 1M | 0.0067825 |
| PMM2 | phosphomannomutase 2 | 0.00676241 |
| SOWAHC | sosondowah ankyrin repeat domain family member C | 0.00671317 |
| HSPA2 | heat shock 70kDa protein 2 | 0.0067045 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | 0.00670209 |
| KLHL41 | kelch-like family member 41 | 0.00668897 |
| GOLIM4 | golgi integral membrane protein 4 | 0.0066443 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00662964 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00661382 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.00647712 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.00647284 |
| LMAN1 | lectin, mannose-binding, 1 | 0.00645315 |
| CHP2 | calcineurin-like EF-hand protein 2 | 0.00643825 |
| GAB2 | GRB2-associated binding protein 2 | 0.00643551 |
| EXOC5 | exocyst complex component 5 | 0.0064355 |
| TDO2 | tryptophan 2,3-dioxygenase | 0.00640729 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00639776 |
| CCN3 | cellular communication network factor 3 | 0.00639578 |
| ACKR3 | atypical chemokine receptor 3 | 0.00639073 |
| NKX2-1 | NK2 homeobox 1 | 0.0063797 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00636359 |
| MYO1D | myosin ID | 0.0063434 |
| ZWILCH | zwilch kinetochore protein | 0.00630603 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.0063007 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | 0.00628474 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.00625636 |
| IRS2 | insulin receptor substrate 2 | 0.00624283 |
| NPEPL1 | aminopeptidase-like 1 | 0.00624015 |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide | 0.00620033 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 0.00619793 |
| KRT20 | keratin 20, type I | 0.00619408 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.00617701 |
| SLN | sarcolipin | 0.00617282 |
| SNX7 | sorting nexin 7 | 0.00617169 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00615665 |
| THBS2 | thrombospondin 2 | 0.00612413 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00608175 |
| C1QA | complement component 1, q subcomponent, A chain | 0.00607053 |
| CA4 | carbonic anhydrase IV | 0.00606146 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A | 0.00603905 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.00603318 |
| AQP8 | aquaporin 8 | 0.00600601 |
| IFRD2 | interferon-related developmental regulator 2 | 0.00599805 |
| PDE4DIP | phosphodiesterase 4D interacting protein | 0.00599689 |
| NAV2 | neuron navigator 2 | 0.00597384 |
| CD177 | CD177 molecule | 0.00595848 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.00593847 |
| ABHD2 | abhydrolase domain containing 2 | 0.0059368 |
| C1QB | complement component 1, q subcomponent, B chain | 0.00592242 |
| RAB7A | RAB7A, member RAS oncogene family | 0.00590819 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00590266 |
| TNNI2 | troponin I type 2 (skeletal, fast) | 0.00588997 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.00588374 |
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked | 0.00588097 |
| PFN2 | profilin 2 | 0.00584598 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00584238 |
| TYRP1 | tyrosinase-related protein 1 | 0.00582848 |
| MYBPC2 | myosin binding protein C, fast type | 0.00581963 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00578297 |
| STK10 | serine/threonine kinase 10 | 0.00577519 |
| DPP4 | dipeptidyl-peptidase 4 | 0.00576385 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00573038 |
| RTN4 | reticulon 4 | 0.00571494 |
| GTF2I | general transcription factor IIi | 0.00571314 |
| CALCA | calcitonin-related polypeptide alpha | 0.00568739 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0056843 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0056833 |
| PDLIM5 | PDZ and LIM domain 5 | 0.00568212 |
| BRD4 | bromodomain containing 4 | 0.00568116 |
| SPEN | spen family transcriptional repressor | 0.00567708 |
| SCARB2 | scavenger receptor class B, member 2 | 0.00566369 |
| PLXNA2 | plexin A2 | 0.00565837 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | 0.00565724 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.00559072 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00558228 |
| KIF1A | kinesin family member 1A | 0.00556651 |
| CD163 | CD163 molecule | 0.00553604 |
| COL11A1 | collagen, type XI, alpha 1 | 0.00553592 |
| TCF21 | transcription factor 21 | 0.00551345 |
| FAM110B | family with sequence similarity 110, member B | 0.00551257 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.00549206 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | 0.00549199 |
| SLC7A6 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 | 0.00549105 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | 0.00548963 |
| KIAA0125 | KIAA0125 | 0.00547669 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00547008 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.00546552 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00545965 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.0054419 |
| ACTA1 | actin, alpha 1, skeletal muscle | 0.00543917 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 | 0.00543147 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00542344 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00542092 |
| PMP22 | peripheral myelin protein 22 | 0.00542072 |
| CH25H | cholesterol 25-hydroxylase | 0.00541682 |
| ANK2 | ankyrin 2, neuronal | 0.00541445 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) | 0.00539644 |
| EDNRB | endothelin receptor type B | 0.00539284 |
| CHRNA1 | cholinergic receptor, nicotinic, alpha 1 (muscle) | 0.00538613 |
| FABP1 | fatty acid binding protein 1, liver | 0.00538545 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.00538061 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.00535991 |
| ZNF91 | zinc finger protein 91 | 0.00533183 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00533169 |
| ADCY9 | adenylate cyclase 9 | 0.00533146 |
| CDV3 | CDV3 homolog (mouse) | 0.00531882 |
| SGCE | sarcoglycan, epsilon | 0.00531655 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.00531409 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00531377 |
| ABHD3 | abhydrolase domain containing 3 | 0.00531271 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.00530976 |
| SECISBP2L | SECIS binding protein 2-like | 0.00528687 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00528522 |
| STMN2 | stathmin 2 | 0.00528358 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | 0.00527032 |
| FLNB | filamin B, beta | 0.00526612 |
| RUNX1 | runt-related transcription factor 1 | 0.00526344 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.00524921 |
| MARCH3 | membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase | 0.00523763 |
| PDGFD | platelet derived growth factor D | 0.0052172 |
| UBAP2L | ubiquitin associated protein 2-like | 0.00520968 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.00519975 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.00518972 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | 0.00518886 |
| BCL2L2 | BCL2-like 2 | 0.00518348 |
| ARCN1 | archain 1 | 0.00518191 |
| SH3BP4 | SH3-domain binding protein 4 | 0.00517309 |
| ZNF432 | zinc finger protein 432 | 0.00516685 |
| BAG2 | BCL2-associated athanogene 2 | 0.0051661 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.00516474 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | 0.00516222 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00514648 |
| NOTCH2NL | notch 2 N-terminal like | 0.00513506 |
| HLX | H2.0-like homeobox | 0.00513258 |
| POPDC3 | popeye domain containing 3 | 0.00510995 |
| EREG | epiregulin | 0.00510468 |
| FNBP1 | formin binding protein 1 | 0.00509494 |
| UBE4A | ubiquitination factor E4A | 0.00509148 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00508561 |
| NSG1 | neuron specific gene family member 1 | 0.00506935 |
| MVP | major vault protein | 0.00506356 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.00506277 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.00505496 |
| FOXO1 | forkhead box O1 | 0.00503446 |
| RDX | radixin | 0.00503021 |
| TUBB4B | tubulin, beta 4B class IVb | 0.00502636 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.00502084 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | 0.00500592 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.00500135 |
| CLDN8 | claudin 8 | 0.00499921 |
| IL1R2 | interleukin 1 receptor, type II | 0.00499632 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 | 0.00499241 |
| CD164 | CD164 molecule, sialomucin | 0.00499135 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.00498146 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00498077 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 0.0049779 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.00496994 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.0049688 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) | 0.00495952 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.00495928 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.00495599 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.00495367 |
| NIT1 | nitrilase 1 | 0.00494834 |
| PRRC2C | proline-rich coiled-coil 2C | 0.00493992 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.00493491 |
| ACTB | actin, beta | 0.00493424 |
| GOLGA8A | golgin A8 family, member A | 0.0049315 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00493088 |
| LRRC2 | leucine rich repeat containing 2 | 0.00492612 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00491369 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0049109 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | 0.00490813 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00489543 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CSTA | cystatin A (stefin A) | -0.015251 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.0135904 |
| MMP7 | matrix metallopeptidase 7 | -0.0134905 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | -0.0128969 |
| KRT15 | keratin 15, type I | -0.011984 |
| KIF20A | kinesin family member 20A | -0.0115969 |
| CLU | clusterin | -0.0115754 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.0109717 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0108263 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0107483 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0105612 |
| TESC | tescalcin | -0.0104427 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.0101561 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.00996469 |
| KRT5 | keratin 5, type II | -0.00989745 |
| ADD3 | adducin 3 (gamma) | -0.0098282 |
| NTS | neurotensin | -0.00975565 |
| CETN2 | centrin, EF-hand protein, 2 | -0.00962577 |
| CLEC11A | C-type lectin domain family 11, member A | -0.00960508 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00939357 |
| CP | ceruloplasmin (ferroxidase) | -0.00917064 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | -0.00916435 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00907834 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00906574 |
| KRT19 | keratin 19, type I | -0.00905361 |
| NELL2 | NEL-like 2 (chicken) | -0.00898732 |
| G0S2 | G0/G1 switch 2 | -0.00887501 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00887477 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00887118 |
| KRT17 | keratin 17, type I | -0.00884931 |
| CD200 | CD200 molecule | -0.00878605 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00874289 |
| LY75 | lymphocyte antigen 75 | -0.0085877 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.00857783 |
| MSLN | mesothelin | -0.00848222 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00839465 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.0083543 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.00824712 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.00821416 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00816831 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00816042 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | -0.00814672 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.00814489 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | -0.00805527 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 | -0.00804775 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00800502 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | -0.00789835 |
| CRIP2 | cysteine-rich protein 2 | -0.00788899 |
| MMP1 | matrix metallopeptidase 1 | -0.00786196 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0078199 |
| KYNU | kynureninase | -0.00778144 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.00766935 |
| GNAS | GNAS complex locus | -0.0076301 |
| MAL | mal, T-cell differentiation protein | -0.00762211 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | -0.00759295 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00734041 |
| SRGN | serglycin | -0.00733413 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00721528 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00721441 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00715562 |
| KRT13 | keratin 13, type I | -0.00713409 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.00705218 |
| NELFE | negative elongation factor complex member E | -0.00701638 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.00694242 |
| TGM2 | transglutaminase 2 | -0.00693412 |
| PLTP | phospholipid transfer protein | -0.00692813 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00688356 |
| FABP6 | fatty acid binding protein 6, ileal | -0.00685228 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0068474 |
| LTF | lactotransferrin | -0.00684129 |
| NMU | neuromedin U | -0.0068296 |
| MARCKSL1 | MARCKS-like 1 | -0.00681413 |
| FAM171A1 | family with sequence similarity 171, member A1 | -0.00679634 |
| CSAD | cysteine sulfinic acid decarboxylase | -0.00679117 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00677535 |
| CLIC1 | chloride intracellular channel 1 | -0.00676178 |
| IL2RG | interleukin 2 receptor, gamma | -0.0067597 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | -0.0067206 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | -0.00670295 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | -0.00664947 |
| DAXX | death-domain associated protein | -0.0066409 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00657305 |
| ISYNA1 | inositol-3-phosphate synthase 1 | -0.00651742 |
| GPR65 | G protein-coupled receptor 65 | -0.00650906 |
| TXNDC15 | thioredoxin domain containing 15 | -0.00650236 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.00649692 |
| MMD | monocyte to macrophage differentiation-associated | -0.00647654 |
| ARL3 | ADP-ribosylation factor-like 3 | -0.00647535 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00646854 |
| PCNA | proliferating cell nuclear antigen | -0.00645497 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.00642272 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00641398 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.00641291 |
| METTL7A | methyltransferase like 7A | -0.00638975 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00638611 |
| KRT14 | keratin 14, type I | -0.00637592 |
| CD48 | CD48 molecule | -0.00637034 |
| LAMA5 | laminin, alpha 5 | -0.00636809 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | -0.00635568 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00633901 |
| VEGFA | vascular endothelial growth factor A | -0.00632411 |
| CHRDL1 | chordin-like 1 | -0.00629408 |
| CD96 | CD96 molecule | -0.00628675 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00628111 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.00625283 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.00624871 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.00624774 |
| FGB | fibrinogen beta chain | -0.00624497 |
| GTPBP8 | GTP-binding protein 8 (putative) | -0.00622995 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.00622917 |
| PCYOX1L | prenylcysteine oxidase 1 like | -0.00619711 |
| BPGM | 2,3-bisphosphoglycerate mutase | -0.00617557 |
| CD2 | CD2 molecule | -0.00617443 |
| RAB40B | RAB40B, member RAS oncogene family | -0.00615751 |
| CAV2 | caveolin 2 | -0.00615695 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -0.006154 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 | -0.00613612 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | -0.00612541 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00608389 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00608167 |
| IL1RN | interleukin 1 receptor antagonist | -0.00605224 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00605144 |
| SCPEP1 | serine carboxypeptidase 1 | -0.0060487 |
| MMP9 | matrix metallopeptidase 9 | -0.00602948 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.00602046 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00600978 |
| HIST3H2A | histone cluster 3, H2a | -0.00598802 |
| RNF5 | ring finger protein 5, E3 ubiquitin protein ligase | -0.00597313 |
| SSR4 | signal sequence receptor, delta | -0.00597044 |
| PTGES | prostaglandin E synthase | -0.00596329 |
| TOB1 | transducer of ERBB2, 1 | -0.00592686 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00592616 |
| HLA-DOB | major histocompatibility complex, class II, DO beta | -0.00592294 |
| GPX1 | glutathione peroxidase 1 | -0.00591006 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | -0.00590908 |
| CST7 | cystatin F (leukocystatin) | -0.00589473 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00588791 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.00587665 |
| ITM2A | integral membrane protein 2A | -0.005864 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 | -0.00584458 |
| CAMLG | calcium modulating ligand | -0.00583963 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.00583482 |
| MUC1 | mucin 1, cell surface associated | -0.00580625 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | -0.00580161 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00580152 |
| MUC16 | mucin 16, cell surface associated | -0.00579512 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00576264 |
| KRT7 | keratin 7, type II | -0.0057571 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00575226 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00574833 |
| C6ORF48 | chromosome 6 open reading frame 48 | -0.00573303 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.0057108 |
| ZNF467 | zinc finger protein 467 | -0.00571025 |
| GRAMD1C | GRAM domain containing 1C | -0.00570765 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.00569805 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | -0.00569318 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | -0.00567726 |
| SLC16A4 | solute carrier family 16, member 4 | -0.00566838 |
| TDP1 | tyrosyl-DNA phosphodiesterase 1 | -0.00566253 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -0.00565392 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00564676 |
| FGG | fibrinogen gamma chain | -0.00562998 |
| SLC2A4RG | SLC2A4 regulator | -0.00562556 |
| ANXA6 | annexin A6 | -0.00561977 |
| COL4A6 | collagen, type IV, alpha 6 | -0.00557525 |
| TBL1X | transducin (beta)-like 1X-linked | -0.00555345 |
| TPI1 | triosephosphate isomerase 1 | -0.00555116 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.00551098 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00550573 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | -0.00549648 |
| MMP10 | matrix metallopeptidase 10 | -0.00549228 |
| GNLY | granulysin | -0.00548285 |
| SEPHS1 | selenophosphate synthetase 1 | -0.00547758 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.00546974 |
| PRAME | preferentially expressed antigen in melanoma | -0.00546258 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00546102 |
| PTK2 | protein tyrosine kinase 2 | -0.0054606 |
| FJX1 | four jointed box 1 (Drosophila) | -0.00544572 |
| WDR61 | WD repeat domain 61 | -0.0054389 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.00542799 |
| RAB33A | RAB33A, member RAS oncogene family | -0.00542746 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | -0.00542466 |
| LYZ | lysozyme | -0.00540524 |
| TMEM243 | transmembrane protein 243, mitochondrial | -0.00538725 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00538104 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | -0.00537712 |
| SCAND1 | SCAN domain containing 1 | -0.00537319 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | -0.00536455 |
| RRAS | related RAS viral (r-ras) oncogene homolog | -0.00536424 |
| MSMB | microseminoprotein, beta- | -0.00533008 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00532915 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00532177 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.00530726 |
| TRH | thyrotropin-releasing hormone | -0.00530021 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00528969 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.00528859 |
| EFCAB11 | EF-hand calcium binding domain 11 | -0.00528076 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -0.00526238 |
| ANTKMT | adenine nucleotide translocase lysine methyltransferase | -0.00525949 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.0052465 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.00524502 |
| PRDX3 | peroxiredoxin 3 | -0.0052438 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.00522944 |
| PLAUR | plasminogen activator, urokinase receptor | -0.00521822 |
| RAI14 | retinoic acid induced 14 | -0.00521382 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0052101 |
| ZGPAT | zinc finger, CCCH-type with G patch domain | -0.00520187 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00520075 |
| CUEDC2 | CUE domain containing 2 | -0.00519613 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0051736 |
| TSPAN13 | tetraspanin 13 | -0.00515402 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00513146 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00512785 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0051221 |
| NEK2 | NIMA-related kinase 2 | -0.00511081 |
| PF4 | platelet factor 4 | -0.00510504 |
| GUK1 | guanylate kinase 1 | -0.00510413 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -0.00509946 |
| METRN | meteorin, glial cell differentiation regulator | -0.00509298 |
| NBEA | neurobeachin | -0.00507753 |
| NELL1 | NEL-like 1 (chicken) | -0.00506778 |
| CNN1 | calponin 1, basic, smooth muscle | -0.00505924 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -0.0050394 |
| RGS4 | regulator of G-protein signaling 4 | -0.00503681 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.0050301 |
| NLRP2 | NLR family, pyrin domain containing 2 | -0.00501992 |
| PITX1 | paired-like homeodomain 1 | -0.00501685 |
| S100A8 | S100 calcium binding protein A8 | -0.00501106 |
| LCN2 | lipocalin 2 | -0.00500882 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00500098 |
| COX7A2L | cytochrome c oxidase subunit VIIa polypeptide 2 like | -0.00499844 |
| ODC1 | ornithine decarboxylase 1 | -0.00499733 |
| C12ORF29 | chromosome 12 open reading frame 29 | -0.00498119 |
| PRPSAP1 | phosphoribosyl pyrophosphate synthetase-associated protein 1 | -0.00497637 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | -0.00497347 |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | -0.00497179 |
| CHMP6 | charged multivesicular body protein 6 | -0.00496004 |
| PTN | pleiotrophin | -0.00494216 |
| PLSCR3 | phospholipid scramblase 3 | -0.00494078 |
| PLIN1 | perilipin 1 | -0.00493178 |
| MT1F | metallothionein 1F | -0.0049305 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 | -0.00492646 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | -0.00492319 |
| CTSW | cathepsin W | -0.00490618 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0049034 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | -0.00490204 |
| FST | follistatin | -0.00490044 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | -0.00489506 |
| RPL13 | ribosomal protein L13 | -0.00489 |
| NDUFB8 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa | -0.00487306 |
