| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | FGR proto-oncogene, Src family tyrosine kinase|This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2268) |
| External Link | https://ncbi.nlm.nih.gov/gene/2268 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the FGR gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0137171 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0102335 |
| CCN2 | cellular communication network factor 2 | 0.00994276 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00984712 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00971732 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 0.00899212 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00869748 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00852458 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.00822527 |
| STK10 | serine/threonine kinase 10 | 0.00821933 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.00801619 |
| RPL36 | ribosomal protein L36 | 0.00800445 |
| HOPX | HOP homeobox | 0.00785085 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | 0.00761375 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00744706 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00739015 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.00737801 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00733022 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00724801 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.00713828 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0070939 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00705932 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.00704743 |
| RPL26L1 | ribosomal protein L26-like 1 | 0.00698403 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | 0.00695568 |
| LRRN3 | leucine rich repeat neuronal 3 | 0.00695362 |
| S100B | S100 calcium binding protein B | 0.00692114 |
| MX1 | MX dynamin-like GTPase 1 | 0.00691264 |
| INHBA | inhibin, beta A | 0.00686074 |
| TSPAN13 | tetraspanin 13 | 0.00682455 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | 0.00678502 |
| IFI44L | interferon-induced protein 44-like | 0.00669511 |
| VDAC1 | voltage-dependent anion channel 1 | 0.00657604 |
| ECM1 | extracellular matrix protein 1 | 0.00656807 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00654071 |
| AHCY | adenosylhomocysteinase | 0.00649955 |
| KLF6 | Kruppel-like factor 6 | 0.00643681 |
| IRF7 | interferon regulatory factor 7 | 0.00640124 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.00639824 |
| KIAA0226L | KIAA0226-like | 0.00638616 |
| CDC42 | cell division cycle 42 | 0.00636152 |
| REG1A | regenerating islet-derived 1 alpha | 0.00635704 |
| CD320 | CD320 molecule | 0.00624794 |
| RPL36AL | ribosomal protein L36a-like | 0.00617676 |
| RPL14 | ribosomal protein L14 | 0.00617203 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00611422 |
| NDUFA7 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa | 0.00609622 |
| RAB32 | RAB32, member RAS oncogene family | 0.00608985 |
| ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) | 0.00608883 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00607598 |
| SKAP1 | src kinase associated phosphoprotein 1 | 0.00605786 |
| ATP5PD | ATP synthase peripheral stalk subunit d | 0.00605533 |
| ERGIC3 | ERGIC and golgi 3 | 0.00604155 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.00604133 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00604089 |
| GPX1 | glutathione peroxidase 1 | 0.00599485 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00598242 |
| UFM1 | ubiquitin-fold modifier 1 | 0.00594225 |
| PHYH | phytanoyl-CoA 2-hydroxylase | 0.00591748 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | 0.00591109 |
| RPS5 | ribosomal protein S5 | 0.00590514 |
| REEP5 | receptor accessory protein 5 | 0.0058962 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.0058899 |
| ENOPH1 | enolase-phosphatase 1 | 0.00588425 |
| LYZ | lysozyme | 0.00588373 |
| SORBS3 | sorbin and SH3 domain containing 3 | 0.00588322 |
| RPS14P3 | ribosomal protein S14 pseudogene 3 | 0.00587119 |
| DACH1 | dachshund family transcription factor 1 | 0.00586521 |
| GNAS | GNAS complex locus | 0.00586463 |
| RPL35 | ribosomal protein L35 | 0.00586239 |
| PLK1 | polo-like kinase 1 | 0.00585908 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00582262 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00579718 |
| CSTA | cystatin A (stefin A) | 0.00578193 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.00572497 |
| ACYP2 | acylphosphatase 2, muscle type | 0.00567317 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 0.0056522 |
| MARCKSL1 | MARCKS-like 1 | 0.00565015 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | 0.00564136 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00561308 |
| NDUFB1 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa | 0.0055917 |
| KRT10 | keratin 10, type I | 0.00551305 |
| TMEM230 | transmembrane protein 230 | 0.00551144 |
| SELL | selectin L | 0.00550921 |
| BTG3 | BTG family, member 3 | 0.00550864 |
| EGR1 | early growth response 1 | 0.00549396 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00548167 |
| RAN | RAN, member RAS oncogene family | 0.00544938 |
| PCNA | proliferating cell nuclear antigen | 0.00542819 |
| MRPL23 | mitochondrial ribosomal protein L23 | 0.00542613 |
| C19ORF53 | chromosome 19 open reading frame 53 | 0.00542291 |
| SCAND1 | SCAN domain containing 1 | 0.00542187 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.00541969 |
| MRPS33 | mitochondrial ribosomal protein S33 | 0.00538114 |
| CCNG2 | cyclin G2 | 0.00536746 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.00536664 |
| MRPS16 | mitochondrial ribosomal protein S16 | 0.00536236 |
| VIM | vimentin | 0.0053532 |
| SSR4 | signal sequence receptor, delta | 0.00534229 |
| RBBP4 | retinoblastoma binding protein 4 | 0.00532615 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.00530082 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | 0.00528742 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00527692 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 0.00527649 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.00527001 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0052613 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.00526039 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00525535 |
| SLC35F2 | solute carrier family 35, member F2 | 0.0052515 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00523109 |
| EMX2 | empty spiracles homeobox 2 | 0.00523085 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.00521866 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.00521118 |
| MZT2A | mitotic spindle organizing protein 2A | 0.00518865 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 | 0.0051837 |
| MAMLD1 | mastermind-like domain containing 1 | 0.00515868 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00515601 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.00515093 |
| LYRM4 | LYR motif containing 4 | 0.00514624 |
| BARD1 | BRCA1 associated RING domain 1 | 0.00514391 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00513652 |
| PCOLCE | procollagen C-endopeptidase enhancer | 0.00511408 |
| ABHD17A | abhydrolase domain containing 17A | 0.00510828 |
| NEBL | nebulette | 0.00510755 |
| TNC | tenascin C | 0.00510094 |
| CENPE | centromere protein E, 312kDa | 0.00508254 |
| SEC61B | Sec61 beta subunit | 0.00503966 |
| ZNF44 | zinc finger protein 44 | 0.00500504 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | 0.00499597 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00499022 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00498667 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00498406 |
| GPX7 | glutathione peroxidase 7 | 0.0049831 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00497062 |
| MSX1 | msh homeobox 1 | 0.00496989 |
| REG1B | regenerating islet-derived 1 beta | 0.00495998 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | 0.00492974 |
| CCDC85B | coiled-coil domain containing 85B | 0.00492585 |
| KIF3B | kinesin family member 3B | 0.00492238 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00491469 |
| NUTF2 | nuclear transport factor 2 | 0.0049103 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A | 0.004907 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.00489117 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0048887 |
| TKTL1 | transketolase-like 1 | 0.00488382 |
| ZNF91 | zinc finger protein 91 | 0.00487968 |
| AKTIP | AKT interacting protein | 0.00486956 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.00486554 |
| CDCA4 | cell division cycle associated 4 | 0.00485602 |
| PCLAF | PCNA clamp associated factor | 0.00485013 |
| AKIRIN1 | akirin 1 | 0.00482938 |
| HNRNPF | heterogeneous nuclear ribonucleoprotein F | 0.00482886 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) | 0.00481005 |
| RETREG1 | reticulophagy regulator 1 | 0.00480427 |
| ZNF652 | zinc finger protein 652 | 0.00480407 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00480341 |
| AMZ2 | archaelysin family metallopeptidase 2 | 0.00480264 |
| MLF1 | myeloid leukemia factor 1 | 0.00479661 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal | 0.00478943 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | 0.00478183 |
| ADK | adenosine kinase | 0.00477581 |
| CRYL1 | crystallin, lambda 1 | 0.00476095 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00475896 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00475281 |
| TXNL4A | thioredoxin-like 4A | 0.00475018 |
| EPCAM | epithelial cell adhesion molecule | 0.00474539 |
| RNASET2 | ribonuclease T2 | 0.00474223 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00471809 |
| RTRAF | RNA transcription, translation and transport factor | 0.00471511 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | 0.00469115 |
| ZNF430 | zinc finger protein 430 | 0.00468364 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00467181 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | 0.00467102 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.00466566 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00466479 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.004654 |
| H1-10 | H1.10 linker histone | 0.00463338 |
| YIPF5 | Yip1 domain family, member 5 | 0.00461793 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | 0.00461046 |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.0046049 |
| FSTL1 | follistatin-like 1 | 0.00460311 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.00458245 |
| ATP5MG | ATP synthase membrane subunit g | 0.00457927 |
| SRPRB | signal recognition particle receptor, B subunit | 0.00457624 |
| LSM7 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00457156 |
| RSL24D1 | ribosomal L24 domain containing 1 | 0.00457083 |
| OSER1 | oxidative stress responsive serine-rich 1 | 0.00456402 |
| GPR171 | G protein-coupled receptor 171 | 0.00456377 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.00455559 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 | 0.00454486 |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P | 0.00454087 |
| PRKCZ | protein kinase C, zeta | 0.00453999 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00452455 |
| COMMD3 | COMM domain containing 3 | 0.00451195 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00450653 |
| COX5A | cytochrome c oxidase subunit Va | 0.00449458 |
| LYRM2 | LYR motif containing 2 | 0.00449312 |
| SELENOT | selenoprotein T | 0.00447843 |
| GPX4 | glutathione peroxidase 4 | 0.00447556 |
| NDUFAB1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | 0.00445839 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain | 0.0044527 |
| PTCH1 | patched 1 | 0.00444828 |
| DEFB1 | defensin, beta 1 | 0.00444503 |
| COMP | cartilage oligomeric matrix protein | 0.00443466 |
| GMFG | glia maturation factor, gamma | 0.00443151 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0044216 |
| GSTA4 | glutathione S-transferase alpha 4 | 0.00441588 |
| MAL | mal, T-cell differentiation protein | 0.00441427 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00441317 |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | 0.00441014 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.00440485 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 0.00440319 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | 0.00440057 |
| CBFB | core-binding factor, beta subunit | 0.00438052 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.00437805 |
| ACAA2 | acetyl-CoA acyltransferase 2 | 0.00437514 |
| PRSS3 | protease, serine, 3 | 0.004365 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00434557 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00434444 |
| ZNF426 | zinc finger protein 426 | 0.004344 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.00433376 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.00433253 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.00432676 |
| RPS27L | ribosomal protein S27-like | 0.00431904 |
| ZNF721 | zinc finger protein 721 | 0.00431275 |
| REG3A | regenerating islet-derived 3 alpha | 0.00431172 |
| IL18 | interleukin 18 | 0.0043037 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.00429967 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.0042948 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00428738 |
| SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide 16kDa | 0.00428691 |
| SAP30BP | SAP30 binding protein | 0.00427688 |
| CTSG | cathepsin G | 0.00427384 |
| STK17A | serine/threonine kinase 17a | 0.00424794 |
| MXRA7 | matrix-remodelling associated 7 | 0.0042479 |
| CFAP20 | cilia and flagella associated protein 20 | 0.00424409 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) | 0.00424237 |
| NUBPL | nucleotide binding protein-like | 0.00424014 |
| IL1A | interleukin 1, alpha | 0.00423916 |
| TPX2 | TPX2, microtubule-associated | 0.00421935 |
| RGS1 | regulator of G-protein signaling 1 | 0.00421207 |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.00421095 |
| CD48 | CD48 molecule | 0.00420913 |
| ZNF277 | zinc finger protein 277 | 0.00419931 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00419882 |
| EFCAB11 | EF-hand calcium binding domain 11 | 0.00419605 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa | 0.00419 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.0041837 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00418087 |
| MRPL17 | mitochondrial ribosomal protein L17 | 0.00417949 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RTN2 | reticulon 2 | -0.0114648 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.0107169 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0106038 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.0105351 |
| MEIS2 | Meis homeobox 2 | -0.0102422 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0100792 |
| KRT23 | keratin 23, type I | -0.00993495 |
| SYNM | synemin, intermediate filament protein | -0.00961909 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.00950172 |
| APOD | apolipoprotein D | -0.00947626 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00939421 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00925768 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | -0.00903801 |
| KRT19 | keratin 19, type I | -0.00898049 |
| CD9 | CD9 molecule | -0.00895856 |
| FKBP4 | FK506 binding protein 4, 59kDa | -0.00886693 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00866841 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00854749 |
| XIC | X chromosome inactivation center | -0.00844615 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -0.00843927 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00836564 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | -0.00829362 |
| DCLK1 | doublecortin-like kinase 1 | -0.00820433 |
| NOTCH2 | notch 2 | -0.0079808 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00790943 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00787486 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00758905 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00750647 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0074822 |
| SOCS1 | suppressor of cytokine signaling 1 | -0.00734075 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00727964 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00727125 |
| CFH | complement factor H | -0.00716447 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00715661 |
| FBLN1 | fibulin 1 | -0.00702664 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | -0.00698797 |
| IGSF3 | immunoglobulin superfamily, member 3 | -0.0069777 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00686291 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | -0.00677792 |
| FGL2 | fibrinogen-like 2 | -0.00675232 |
| TGM2 | transglutaminase 2 | -0.00673175 |
| DES | desmin | -0.00672804 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -0.00671474 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00667959 |
| TNS1 | tensin 1 | -0.00667475 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00660191 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | -0.00652142 |
| MAOB | monoamine oxidase B | -0.00648008 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | -0.00645598 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00642966 |
| NLGN4X | neuroligin 4, X-linked | -0.00639775 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.00638809 |
| ORC1 | origin recognition complex, subunit 1 | -0.00637542 |
| PALLD | palladin, cytoskeletal associated protein | -0.00636526 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00635429 |
| OGN | osteoglycin | -0.00635242 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.00634331 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.00629707 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00624401 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00624365 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00623603 |
| KRT15 | keratin 15, type I | -0.00622014 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00619499 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00619179 |
| GSDME | gasdermin E | -0.00617517 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.00616482 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | -0.00615274 |
| ZBTB16 | zinc finger and BTB domain containing 16 | -0.00609168 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.00609155 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | -0.00606608 |
| CD58 | CD58 molecule | -0.00605905 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00603147 |
| TMEM176B | transmembrane protein 176B | -0.00601186 |
| PLPP3 | phospholipid phosphatase 3 | -0.00599871 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | -0.00595654 |
| RPIA | ribose 5-phosphate isomerase A | -0.00594343 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00593287 |
| MRTFB | myocardin related transcription factor B | -0.0059233 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.00585815 |
| MXI1 | MAX interactor 1, dimerization protein | -0.00581257 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.00581143 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00581113 |
| TFRC | transferrin receptor | -0.00581068 |
| NELL2 | NEL-like 2 (chicken) | -0.00576398 |
| WISP2 | WNT1 inducible signaling pathway protein 2 | -0.00572823 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0056956 |
| RTN1 | reticulon 1 | -0.00569071 |
| MYOF | myoferlin | -0.00568276 |
| HSPB8 | heat shock 22kDa protein 8 | -0.0056479 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00560182 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00559052 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.0055306 |
| NCOA3 | nuclear receptor coactivator 3 | -0.00551136 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00548374 |
| PTDSS1 | phosphatidylserine synthase 1 | -0.00547591 |
| WASF1 | WAS protein family, member 1 | -0.00547361 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00544713 |
| SVIL | supervillin | -0.00543909 |
| MTERF3 | mitochondrial transcription termination factor 3 | -0.00542925 |
| DST | dystonin | -0.00542135 |
| NIT1 | nitrilase 1 | -0.00540241 |
| PMP22 | peripheral myelin protein 22 | -0.00540202 |
| KRT13 | keratin 13, type I | -0.00538997 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | -0.00538872 |
| APOB | apolipoprotein B | -0.00538473 |
| ALB | albumin | -0.00536583 |
| CP | ceruloplasmin (ferroxidase) | -0.00536353 |
| CLIP3 | CAP-GLY domain containing linker protein 3 | -0.00536083 |
| STK3 | serine/threonine kinase 3 | -0.0053246 |
| PUDP | pseudouridine 5'-phosphatase | -0.00530837 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | -0.00530665 |
| SDCBP | syndecan binding protein (syntenin) | -0.00530263 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00530036 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.00529639 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00527659 |
| CLU | clusterin | -0.00525908 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00523124 |
| EPHA4 | EPH receptor A4 | -0.00522878 |
| MMP2 | matrix metallopeptidase 2 | -0.005203 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.00518345 |
| ADCY1 | adenylate cyclase 1 (brain) | -0.00516894 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00516483 |
| MLPH | melanophilin | -0.00516401 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) | -0.00515428 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00515087 |
| HEATR1 | HEAT repeat containing 1 | -0.00514388 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.00514185 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.00513847 |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs | -0.00513361 |
| ANK2 | ankyrin 2, neuronal | -0.00513202 |
| TPBG | trophoblast glycoprotein | -0.00512481 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.0051105 |
| SELENBP1 | selenium binding protein 1 | -0.00509863 |
| SLC43A3 | solute carrier family 43, member 3 | -0.00509485 |
| LY96 | lymphocyte antigen 96 | -0.00509409 |
| MEST | mesoderm specific transcript | -0.00509104 |
| MAOA | monoamine oxidase A | -0.00509059 |
| UBE3B | ubiquitin protein ligase E3B | -0.00507998 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00507545 |
| IL1R1 | interleukin 1 receptor, type I | -0.00507349 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.00504184 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.00502553 |
| RNF115 | ring finger protein 115 | -0.0050238 |
| LRRC17 | leucine rich repeat containing 17 | -0.00502103 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.00501943 |
| MKRN1 | makorin ring finger protein 1 | -0.00501307 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | -0.00501202 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | -0.00499127 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00499076 |
| RXRA | retinoid X receptor, alpha | -0.00498934 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.00498494 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.00497918 |
| DCX | doublecortin | -0.00497662 |
| SIRPA | signal-regulatory protein alpha | -0.00496278 |
| INTS8 | integrator complex subunit 8 | -0.00495965 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.00495788 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | -0.00495774 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00493031 |
| TGOLN2 | trans-golgi network protein 2 | -0.00491088 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | -0.00488918 |
| IRS1 | insulin receptor substrate 1 | -0.00488488 |
| CD163 | CD163 molecule | -0.00488045 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00486614 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | -0.00486488 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta | -0.00486145 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00484397 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.00483943 |
| MAPK1 | mitogen-activated protein kinase 1 | -0.00483172 |
| MFAP4 | microfibrillar-associated protein 4 | -0.00482987 |
| PRRC2C | proline-rich coiled-coil 2C | -0.00482705 |
| HDGF | hepatoma-derived growth factor | -0.00482223 |
| SGCE | sarcoglycan, epsilon | -0.00482124 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.00481758 |
| SSPN | sarcospan | -0.00480763 |
| TMED5 | transmembrane emp24 protein transport domain containing 5 | -0.00479882 |
| FECH | ferrochelatase | -0.00475149 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00474295 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.00473868 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00473642 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -0.0047338 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.00473208 |
| PEG3 | paternally expressed 3 | -0.00472598 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.00471268 |
| HIPK1 | homeodomain interacting protein kinase 1 | -0.00469518 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00468152 |
| SLAMF8 | SLAM family member 8 | -0.00468098 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.00467506 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00467119 |
| ZNF395 | zinc finger protein 395 | -0.00467119 |
| CLIC2 | chloride intracellular channel 2 | -0.00466594 |
| PLTP | phospholipid transfer protein | -0.00465824 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | -0.00464608 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | -0.00463221 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00462419 |
| FAM120A | family with sequence similarity 120A | -0.00461787 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.00461421 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 | -0.00461187 |
| ACTR1A | ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) | -0.00460227 |
| C1R | complement component 1, r subcomponent | -0.00459456 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.00459338 |
| FHOD3 | formin homology 2 domain containing 3 | -0.00458422 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | -0.0045754 |
| GMPR | guanosine monophosphate reductase | -0.00456261 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.00454287 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | -0.00454189 |
| TOR1A | torsin family 1, member A (torsin A) | -0.00453641 |
| GEM | GTP binding protein overexpressed in skeletal muscle | -0.00453503 |
| TLN1 | talin 1 | -0.0045317 |
| SUSD4 | sushi domain containing 4 | -0.00452575 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.00452211 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00450973 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.00450694 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.00450165 |
| MYBPC2 | myosin binding protein C, fast type | -0.00449969 |
| SOBP | sine oculis binding protein homolog (Drosophila) | -0.00449846 |
| METTL7A | methyltransferase like 7A | -0.00449365 |
| MITF | microphthalmia-associated transcription factor | -0.00449066 |
| NUCB1 | nucleobindin 1 | -0.00448908 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 | -0.00448053 |
| PAEP | progestagen-associated endometrial protein | -0.00446671 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.00446153 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.00446142 |
| NFASC | neurofascin | -0.004461 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00445706 |
| CFD | complement factor D (adipsin) | -0.00443994 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00443964 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | -0.00442962 |
| STC2 | stanniocalcin 2 | -0.0044123 |
| CISD1 | CDGSH iron sulfur domain 1 | -0.00441013 |
| MFAP5 | microfibrillar associated protein 5 | -0.00439637 |
| COLEC12 | collectin sub-family member 12 | -0.00439003 |
| PIP | prolactin-induced protein | -0.00438965 |
| TPD52L1 | tumor protein D52-like 1 | -0.00438758 |
| RTN4 | reticulon 4 | -0.00438486 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.00438461 |
| ADGRL4 | adhesion G protein-coupled receptor L4 | -0.00438254 |
| CD44 | CD44 molecule (Indian blood group) | -0.00437852 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -0.00436793 |
| XPO7 | exportin 7 | -0.00436025 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00435966 |
| TNXB | tenascin XB | -0.00435458 |
| SMC1A | structural maintenance of chromosomes 1A | -0.00435125 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.00435058 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00435052 |
| CD1E | CD1e molecule | -0.00435044 |
| A2M | alpha-2-macroglobulin | -0.0043299 |
| GPC3 | glypican 3 | -0.00432724 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00432411 |
| PDE4A | phosphodiesterase 4A, cAMP-specific | -0.00431683 |
