FGR Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description FGR proto-oncogene, Src family tyrosine kinase|This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2268)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_FGR
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Genes

32 co-expressed genes for FGR from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AIF1 allograft inflammatory factor 1
AOAH acyloxyacyl hydrolase (neutrophil)
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa
CASP1 caspase 1, apoptosis-related cysteine peptidase
CFP complement factor properdin
CMTM6 CKLF-like MARVEL transmembrane domain containing 6
COTL1 coactosin-like F-actin binding protein 1
CTSS cathepsin S
EFHD2 EF-hand domain family, member D2
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FGL2 fibrinogen-like 2
FGR FGR proto-oncogene, Src family tyrosine kinase
GMIP GEM interacting protein
HCK HCK proto-oncogene, Src family tyrosine kinase
IFI30 interferon, gamma-inducible protein 30
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
PYCARD PYD and CARD domain containing
RGS19 regulator of G-protein signaling 19
RGS2 regulator of G-protein signaling 2
RHOG ras homolog family member G
RIN3 Ras and Rab interactor 3
S100A4 S100 calcium binding protein A4
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
THEMIS2 thymocyte selection associated family member 2
TMEM127 transmembrane protein 127
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TYROBP TYRO protein tyrosine kinase binding protein