| Dataset | NURSA Protein-Protein Interactions |
| Category | proteomics |
| Type | interacting protein |
| Description | FGR proto-oncogene, Src family tyrosine kinase|This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2268) |
| External Link | http://www.ncbi.nlm.nih.gov/gene/2268 |
| Similar Terms | |
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4 interacting proteins for FGR from the NURSA Protein-Protein Interactions dataset.
