| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | four and a half LIM domains 2|This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 2274) |
| External Link | https://ncbi.nlm.nih.gov/gene/2274 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the FHL2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IFI27 | interferon, alpha-inducible protein 27 | 0.0106317 |
| HOPX | HOP homeobox | 0.00927292 |
| IFI44L | interferon-induced protein 44-like | 0.00922653 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00832487 |
| DIPK1A | divergent protein kinase domain 1A | 0.00806579 |
| ATF3 | activating transcription factor 3 | 0.00792419 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.00747671 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00734736 |
| FST | follistatin | 0.00721349 |
| KRT7 | keratin 7, type II | 0.00721272 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00680478 |
| EVI2A | ecotropic viral integration site 2A | 0.00664917 |
| ITM2A | integral membrane protein 2A | 0.00663334 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00662943 |
| TUFT1 | tuftelin 1 | 0.00658473 |
| DUSP5 | dual specificity phosphatase 5 | 0.00648818 |
| AXL | AXL receptor tyrosine kinase | 0.00636944 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.00635995 |
| SDC4 | syndecan 4 | 0.00634521 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.00629168 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | 0.00628327 |
| PLAU | plasminogen activator, urokinase | 0.00626174 |
| CYB561 | cytochrome b561 | 0.00621443 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.00616465 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00613648 |
| TSPAN8 | tetraspanin 8 | 0.00598267 |
| ADM | adrenomedullin | 0.00590619 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00588179 |
| KLF6 | Kruppel-like factor 6 | 0.00584135 |
| IFI44 | interferon-induced protein 44 | 0.00583337 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00581816 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00576871 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00574149 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00569775 |
| IL32 | interleukin 32 | 0.00568109 |
| EGR1 | early growth response 1 | 0.00564219 |
| GATA3 | GATA binding protein 3 | 0.00562788 |
| THBS1 | thrombospondin 1 | 0.00543605 |
| PPA1 | pyrophosphatase (inorganic) 1 | 0.00530653 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.00527187 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 0.00524767 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00522513 |
| POPDC3 | popeye domain containing 3 | 0.00521358 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0052039 |
| CLEC2B | C-type lectin domain family 2, member B | 0.0051746 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00517333 |
| VIM | vimentin | 0.00513943 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00513298 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.00508111 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00506156 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00502899 |
| ADRB2 | adrenoceptor beta 2, surface | 0.00500851 |
| CST6 | cystatin E/M | 0.00499634 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00498719 |
| CTSS | cathepsin S | 0.00497152 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.00496351 |
| EDF1 | endothelial differentiation-related factor 1 | 0.00495315 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.00495301 |
| MIR22HG | MIR22 host gene | 0.00490127 |
| NPR3 | natriuretic peptide receptor 3 | 0.00489928 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00488 |
| C3 | complement component 3 | 0.00486952 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00486474 |
| RAB21 | RAB21, member RAS oncogene family | 0.00486247 |
| EGR3 | early growth response 3 | 0.00485853 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00484989 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00483885 |
| SRGN | serglycin | 0.00482724 |
| OPTN | optineurin | 0.00481831 |
| RHOA | ras homolog family member A | 0.00481414 |
| HLA-B | major histocompatibility complex, class I, B | 0.00477644 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00474234 |
| S100A10 | S100 calcium binding protein A10 | 0.00473668 |
| TYRP1 | tyrosinase-related protein 1 | 0.00472803 |
| UFM1 | ubiquitin-fold modifier 1 | 0.00472097 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | 0.00471048 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00470375 |
| MCL1 | myeloid cell leukemia 1 | 0.00470258 |
| DSG1 | desmoglein 1 | 0.00470229 |
| TOX3 | TOX high mobility group box family member 3 | 0.00467762 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00466247 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00465981 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00465877 |
| TBC1D15 | TBC1 domain family, member 15 | 0.00463104 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00462766 |
| KDSR | 3-ketodihydrosphingosine reductase | 0.00461844 |
| VNN1 | vanin 1 | 0.00460579 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00459396 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.00457871 |
| FERMT1 | fermitin family member 1 | 0.00456733 |
| KRT8 | keratin 8, type II | 0.0045666 |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | 0.00456444 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.00455309 |
| CLTB | clathrin, light chain B | 0.00454423 |
| PDE4DIP | phosphodiesterase 4D interacting protein | 0.00454404 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | 0.00453095 |
| COMMD3 | COMM domain containing 3 | 0.00451494 |
| MRPS16 | mitochondrial ribosomal protein S16 | 0.00451114 |
| IL18 | interleukin 18 | 0.00450123 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00448758 |
| MAGT1 | magnesium transporter 1 | 0.00444673 |
| PNMA2 | paraneoplastic Ma antigen 2 | 0.00443607 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | 0.00443467 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00443332 |
| RPS14P3 | ribosomal protein S14 pseudogene 3 | 0.00442191 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00440953 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0043873 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00438203 |
| DHDDS | dehydrodolichyl diphosphate synthase | 0.00437477 |
| CCNA2 | cyclin A2 | 0.00436737 |
| PHF11 | PHD finger protein 11 | 0.0043649 |
| KLK5 | kallikrein-related peptidase 5 | 0.00436125 |
| SERINC3 | serine incorporator 3 | 0.00434834 |
| CD52 | CD52 molecule | 0.0043399 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00432344 |
| MVP | major vault protein | 0.00430235 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | 0.0042931 |
| LIF | leukemia inhibitory factor | 0.00428627 |
| PCNA | proliferating cell nuclear antigen | 0.00428441 |
| CLDND1 | claudin domain containing 1 | 0.00426424 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.00424649 |
| HSPA13 | heat shock protein 70kDa family, member 13 | 0.00423735 |
| KCTD5 | potassium channel tetramerization domain containing 5 | 0.00423394 |
| STOM | stomatin | 0.00423188 |
| LTF | lactotransferrin | 0.00422901 |
| ANXA5 | annexin A5 | 0.00422264 |
| DCTN3 | dynactin 3 (p22) | 0.00419209 |
| NSA2 | NSA2 ribosome biogenesis homolog (S. cerevisiae) | 0.00419032 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | 0.00418648 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 0.00417872 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00417558 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.00416262 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.00416221 |
| EMP1 | epithelial membrane protein 1 | 0.00413588 |
| EGR2 | early growth response 2 | 0.00413303 |
| KRT14 | keratin 14, type I | 0.00412425 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00412163 |
| MICB | MHC class I polypeptide-related sequence B | 0.00411926 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.00411574 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00411308 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 0.00410711 |
| STK17A | serine/threonine kinase 17a | 0.00408279 |
| RIOK3 | RIO kinase 3 | 0.00407963 |
| CDA | cytidine deaminase | 0.0040777 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.00404026 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.00402693 |
| ARG1 | arginase 1 | 0.00402691 |
| CLDN4 | claudin 4 | 0.00402632 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.00401616 |
| FABP7 | fatty acid binding protein 7, brain | 0.00400585 |
| GLTP | glycolipid transfer protein | 0.00400285 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | 0.00398062 |
| ERGIC3 | ERGIC and golgi 3 | 0.00397647 |
| CEP57 | centrosomal protein 57kDa | 0.00397405 |
| REXO2 | RNA exonuclease 2 | 0.00396594 |
| RPL36 | ribosomal protein L36 | 0.00396356 |
| RDX | radixin | 0.00395954 |
| ATG4A | autophagy related 4A, cysteine peptidase | 0.00394118 |
| PLPP2 | phospholipid phosphatase 2 | 0.00393812 |
| ACE2 | angiotensin I converting enzyme 2 | 0.00393348 |
| PTGES | prostaglandin E synthase | 0.00392175 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.00391991 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.00391783 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.00389062 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 | 0.00388754 |
| S100A7 | S100 calcium binding protein A7 | 0.00388752 |
| DSC1 | desmocollin 1 | 0.00387186 |
| ETHE1 | ethylmalonic encephalopathy 1 | 0.00386485 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.0038587 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.00385518 |
| CLU | clusterin | 0.0038422 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 0.00383988 |
| LOR | loricrin | 0.00383386 |
| LYRM4 | LYR motif containing 4 | 0.0038331 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0038288 |
| REEP5 | receptor accessory protein 5 | 0.00382121 |
| RHOC | ras homolog family member C | 0.00380952 |
| CPM | carboxypeptidase M | 0.00380948 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.00380941 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.00380823 |
| TRIB3 | tribbles pseudokinase 3 | 0.00380757 |
| TXNL1 | thioredoxin-like 1 | 0.00380466 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.00379715 |
| KRT17 | keratin 17, type I | 0.00378544 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.00377463 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.00377196 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.00377172 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.00375755 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 | 0.00375729 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0037555 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00375361 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00375229 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00375132 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00374977 |
| EZR | ezrin | 0.00374799 |
| RNF167 | ring finger protein 167 | 0.00374668 |
| AVPI1 | arginine vasopressin-induced 1 | 0.00374242 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 0.00373579 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00373258 |
| ADCY7 | adenylate cyclase 7 | 0.00373091 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.00372464 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00372379 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00372259 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.00372045 |
| CHMP5 | charged multivesicular body protein 5 | 0.00371896 |
| PRSS3 | protease, serine, 3 | 0.00371674 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.00371549 |
| FOSL1 | FOS-like antigen 1 | 0.0037153 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | 0.00370781 |
| ZNF91 | zinc finger protein 91 | 0.00369115 |
| ENO1 | enolase 1, (alpha) | 0.00367906 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | 0.00367506 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.00367283 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 | 0.00366597 |
| OSER1 | oxidative stress responsive serine-rich 1 | 0.00366499 |
| FGL2 | fibrinogen-like 2 | 0.00366434 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00365626 |
| HMOX2 | heme oxygenase 2 | 0.00365575 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00363843 |
| OTULINL | OTU deubiquitinase with linear linkage specificity like | 0.00363688 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | 0.00363197 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.00363077 |
| CST1 | cystatin SN | 0.00362889 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | 0.003616 |
| VAMP4 | vesicle-associated membrane protein 4 | 0.00360706 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00360544 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.00360048 |
| COX15 | cytochrome c oxidase assembly homolog 15 (yeast) | 0.00359935 |
| GPR171 | G protein-coupled receptor 171 | 0.00359443 |
| GLRX | glutaredoxin (thioltransferase) | 0.00359135 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00358836 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.00358445 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like | 0.00357918 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.00356869 |
| FN1 | fibronectin 1 | 0.0035683 |
| MEP1A | meprin A, alpha (PABA peptide hydrolase) | 0.00356244 |
| ZNF410 | zinc finger protein 410 | 0.00355995 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0035487 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00354651 |
| HIST1H2AE | histone cluster 1, H2ae | 0.00353874 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00353803 |
| H1-0 | H1.0 linker histone | 0.00353161 |
| EIF3I | eukaryotic translation initiation factor 3, subunit I | 0.00353023 |
| AGTR1 | angiotensin II receptor, type 1 | 0.00352762 |
| SCEL | sciellin | 0.00352164 |
| MAMLD1 | mastermind-like domain containing 1 | 0.00351145 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 | 0.00350433 |
| HMGA1 | high mobility group AT-hook 1 | 0.0034992 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00349461 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.00348697 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0107218 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0097397 |
| MGP | matrix Gla protein | -0.00959788 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00777778 |
| BGN | biglycan | -0.0077304 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.0076719 |
| PROM1 | prominin 1 | -0.00749286 |
| FHL2 | four and a half LIM domains 2 | -0.00718726 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | -0.00717172 |
| A2M | alpha-2-macroglobulin | -0.00715971 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | -0.00695521 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00690161 |
| TSPYL5 | TSPY-like 5 | -0.00686902 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00683317 |
| TGM2 | transglutaminase 2 | -0.00682698 |
| HOXB2 | homeobox B2 | -0.00681492 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00678505 |
| RGS5 | regulator of G-protein signaling 5 | -0.0067201 |
| MMP7 | matrix metallopeptidase 7 | -0.00665376 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.00657971 |
| ISYNA1 | inositol-3-phosphate synthase 1 | -0.00654991 |
| NID1 | nidogen 1 | -0.00653937 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.0064894 |
| SYT1 | synaptotagmin I | -0.0064039 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.00627854 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.00627607 |
| VWF | von Willebrand factor | -0.006272 |
| ANXA4 | annexin A4 | -0.00610501 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00609109 |
| KAZN | kazrin, periplakin interacting protein | -0.00604869 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00604555 |
| KIF20A | kinesin family member 20A | -0.00600508 |
| GNAS | GNAS complex locus | -0.00589499 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00587049 |
| MAGED1 | melanoma antigen family D1 | -0.00586455 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.00585838 |
| GATA2 | GATA binding protein 2 | -0.00575863 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00571216 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.0056772 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00565061 |
| C14ORF132 | chromosome 14 open reading frame 132 | -0.00564336 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00558571 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | -0.00557793 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | -0.00552552 |
| MGLL | monoglyceride lipase | -0.00550316 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.00548084 |
| CENPE | centromere protein E, 312kDa | -0.0054735 |
| SVIL | supervillin | -0.00546509 |
| NTS | neurotensin | -0.0054037 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | -0.00534645 |
| PCP4 | Purkinje cell protein 4 | -0.00527882 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00525631 |
| CBS | cystathionine-beta-synthase | -0.0052445 |
| TNS1 | tensin 1 | -0.00523132 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00521424 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.0052051 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00519058 |
| SPRY2 | sprouty homolog 2 (Drosophila) | -0.00517308 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00517122 |
| TBX2 | T-box 2 | -0.00516888 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.00514797 |
| MMP1 | matrix metallopeptidase 1 | -0.00513886 |
| CD200 | CD200 molecule | -0.00510017 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -0.00506701 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00506304 |
| PLXND1 | plexin D1 | -0.00504273 |
| OBSL1 | obscurin-like 1 | -0.00504207 |
| TMEM131 | transmembrane protein 131 | -0.00503994 |
| BPIFA1 | BPI fold containing family A, member 1 | -0.00501439 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.00501169 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | -0.00499415 |
| LAMB1 | laminin, beta 1 | -0.00499059 |
| TSPO | translocator protein (18kDa) | -0.00497227 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00497115 |
| MAGEF1 | melanoma antigen family F1 | -0.00496079 |
| MARCKSL1 | MARCKS-like 1 | -0.00495986 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.00495005 |
| CD81 | CD81 molecule | -0.00494241 |
| LOC283683 | uncharacterized LOC283683 | -0.00491832 |
| XIC | X chromosome inactivation center | -0.00491025 |
| STK26 | serine/threonine protein kinase 26 | -0.0048985 |
| PEG10 | paternally expressed 10 | -0.00489729 |
| CAB39 | calcium binding protein 39 | -0.00487849 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | -0.00486897 |
| ADCY1 | adenylate cyclase 1 (brain) | -0.00486813 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00485238 |
| TRIB2 | tribbles pseudokinase 2 | -0.00484343 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00481266 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -0.00481135 |
| MATN2 | matrilin 2 | -0.00480505 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00478784 |
| PRAME | preferentially expressed antigen in melanoma | -0.00477719 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | -0.00477418 |
| NCAM1 | neural cell adhesion molecule 1 | -0.00477389 |
| NREP | neuronal regeneration related protein | -0.00476958 |
| CUX1 | cut-like homeobox 1 | -0.00475394 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | -0.00475007 |
| HMGB3 | high mobility group box 3 | -0.00474393 |
| GLUL | glutamate-ammonia ligase | -0.00472296 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0047159 |
| C7 | complement component 7 | -0.00470077 |
| SDC2 | syndecan 2 | -0.00467762 |
| CD93 | CD93 molecule | -0.0046744 |
| DCHS1 | dachsous cadherin-related 1 | -0.00459919 |
| MEOX2 | mesenchyme homeobox 2 | -0.00459728 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.00459513 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00459402 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | -0.00458761 |
| TRIP13 | thyroid hormone receptor interactor 13 | -0.00457106 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.004564 |
| RNF130 | ring finger protein 130 | -0.00455221 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00455211 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | -0.00454679 |
| FGG | fibrinogen gamma chain | -0.00454413 |
| NINL | ninein-like | -0.00453762 |
| FLOT2 | flotillin 2 | -0.00451228 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | -0.00450271 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.00450142 |
| TBC1D16 | TBC1 domain family, member 16 | -0.00447318 |
| MAGEA3 | melanoma antigen family A3 | -0.00444588 |
| SMC1A | structural maintenance of chromosomes 1A | -0.00444386 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.00442773 |
| WT1 | Wilms tumor 1 | -0.00441651 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0043879 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.00438735 |
| CDC45 | cell division cycle 45 | -0.00438311 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | -0.00436075 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00434994 |
| ELOVL2 | ELOVL fatty acid elongase 2 | -0.00434579 |
| CSRP1 | cysteine and glycine-rich protein 1 | -0.00434206 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00429629 |
| EMILIN1 | elastin microfibril interfacer 1 | -0.00429623 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00428312 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.00426683 |
| KIAA0100 | KIAA0100 | -0.00426272 |
| BCHE | butyrylcholinesterase | -0.00425029 |
| SCARB1 | scavenger receptor class B, member 1 | -0.00424289 |
| WFS1 | Wolfram syndrome 1 (wolframin) | -0.00424193 |
| LRRC17 | leucine rich repeat containing 17 | -0.00424123 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | -0.00423763 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00423435 |
| GUSB | glucuronidase, beta | -0.00422515 |
| HDAC4 | histone deacetylase 4 | -0.0042239 |
| UBE3C | ubiquitin protein ligase E3C | -0.00420193 |
| PRPF4 | pre-mRNA processing factor 4 | -0.00420053 |
| GNMT | glycine N-methyltransferase | -0.00418971 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00418718 |
| FZD6 | frizzled class receptor 6 | -0.00417904 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00415574 |
| COL5A2 | collagen, type V, alpha 2 | -0.00413473 |
| HIRA | histone cell cycle regulator | -0.00411999 |
| VLDLR | very low density lipoprotein receptor | -0.00411726 |
| PTDSS1 | phosphatidylserine synthase 1 | -0.00409612 |
| CD38 | CD38 molecule | -0.00408278 |
| LRP5 | low density lipoprotein receptor-related protein 5 | -0.00407413 |
| DES | desmin | -0.00406766 |
| THSD7A | thrombospondin, type I, domain containing 7A | -0.0040581 |
| MEIS1 | Meis homeobox 1 | -0.00405759 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | -0.00404679 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | -0.00404248 |
| TCF7L1 | transcription factor 7-like 1 (T-cell specific, HMG-box) | -0.00403305 |
| GSTP1 | glutathione S-transferase pi 1 | -0.00399902 |
| RASL11B | RAS-like, family 11, member B | -0.00399448 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.00398967 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.0039886 |
| COL6A1 | collagen, type VI, alpha 1 | -0.00398833 |
| LMNB1 | lamin B1 | -0.00396429 |
| CD320 | CD320 molecule | -0.00396308 |
| SQLE | squalene epoxidase | -0.00396289 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.0039549 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | -0.00395337 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00395187 |
| IRAG2 | inositol 1,4,5-triphosphate receptor associated 2 | -0.00395097 |
| NEFM | neurofilament, medium polypeptide | -0.00394701 |
| EPHA3 | EPH receptor A3 | -0.00394635 |
| SEC24B | SEC24 family member B | -0.00394339 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 | -0.00394327 |
| ISOC1 | isochorismatase domain containing 1 | -0.0039086 |
| MFAP4 | microfibrillar-associated protein 4 | -0.0039045 |
| LBH | limb bud and heart development | -0.00389613 |
| DPY19L4 | dpy-19-like 4 (C. elegans) | -0.00387467 |
| KRT13 | keratin 13, type I | -0.00386162 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.00384682 |
| PLAT | plasminogen activator, tissue | -0.00384139 |
| TPR | translocated promoter region, nuclear basket protein | -0.00383685 |
| ASRGL1 | asparaginase like 1 | -0.00383297 |
| LYZ | lysozyme | -0.00383214 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | -0.00382372 |
| OGN | osteoglycin | -0.00381063 |
| EFNB3 | ephrin-B3 | -0.00380843 |
| BAHCC1 | BAH domain and coiled-coil containing 1 | -0.00379686 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00378679 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00378446 |
| EHD3 | EH-domain containing 3 | -0.00377222 |
| GAMT | guanidinoacetate N-methyltransferase | -0.00376844 |
| FAM168B | family with sequence similarity 168, member B | -0.00376296 |
| SPRR3 | small proline-rich protein 3 | -0.00376228 |
| IRS1 | insulin receptor substrate 1 | -0.00376 |
| MCM6 | minichromosome maintenance complex component 6 | -0.00375464 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.00374631 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | -0.00374621 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00374593 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0037265 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00371711 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00371327 |
| DEFB1 | defensin, beta 1 | -0.0037077 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 | -0.00370737 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.00370451 |
| CFD | complement factor D (adipsin) | -0.00370159 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.00369805 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | -0.00369487 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.00369435 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.00369049 |
| IQSEC1 | IQ motif and Sec7 domain 1 | -0.00368669 |
| MSLN | mesothelin | -0.0036767 |
| MAGEA12 | melanoma antigen family A12 | -0.00366804 |
| APOD | apolipoprotein D | -0.00366423 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | -0.00366341 |
| CCL15 | chemokine (C-C motif) ligand 15 | -0.00364666 |
| MAML1 | mastermind-like 1 (Drosophila) | -0.00364609 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.00362063 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | -0.00361736 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.00361354 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -0.0036125 |
| ELN | elastin | -0.00360739 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.00360585 |
| STARD7 | StAR-related lipid transfer (START) domain containing 7 | -0.00360525 |
| GYS1 | glycogen synthase 1 (muscle) | -0.00359524 |
| RTN2 | reticulon 2 | -0.00359386 |
| TIE1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | -0.00358947 |
| PDGFD | platelet derived growth factor D | -0.00358777 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -0.00358486 |
| SPP1 | secreted phosphoprotein 1 | -0.00357092 |
| DNM1L | dynamin 1-like | -0.0035703 |
| GPC1 | glypican 1 | -0.00356164 |
| RNASET2 | ribonuclease T2 | -0.00355615 |
| PDE10A | phosphodiesterase 10A | -0.00354604 |
| PLTP | phospholipid transfer protein | -0.00354154 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | -0.00353985 |
| CTPS1 | CTP synthase 1 | -0.00353405 |
| PEG3 | paternally expressed 3 | -0.00353265 |
| PCGF2 | polycomb group ring finger 2 | -0.0035318 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00352989 |
| GLB1L2 | galactosidase, beta 1-like 2 | -0.00352876 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.00352408 |
| NBEA | neurobeachin | -0.00352297 |
| PI4KA | phosphatidylinositol 4-kinase, catalytic, alpha | -0.00351747 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.00351651 |
