FLI1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description Fli-1 proto-oncogene, ETS transcription factor|This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] (NCBI Entrez Gene Database, 2313)
External Link http://www.ncbi.nlm.nih.gov/gene/2313
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Genes

28 interacting proteins for FLI1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
BRCA1 breast cancer 1, early onset
ELK1 ELK1, member of ETS oncogene family
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV6 ets variant 6
EWSR1 EWS RNA-binding protein 1
FMNL1 formin-like 1
GATA1 GATA binding protein 1 (globin transcription factor 1)
KLF1 Kruppel-like factor 1 (erythroid)
MAPK1 mitogen-activated protein kinase 1
MAPK15 mitogen-activated protein kinase 15
MAPK3 mitogen-activated protein kinase 3
MAPK6 mitogen-activated protein kinase 6
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
PIAS1 protein inhibitor of activated STAT, 1
PIAS2 protein inhibitor of activated STAT, 2
PRKCD protein kinase C, delta
SMAD3 SMAD family member 3
SMAD9 SMAD family member 9
SNRPC small nuclear ribonucleoprotein polypeptide C
SP100 SP100 nuclear antigen
SRF serum response factor (c-fos serum response element-binding transcription factor)
SUMO1 small ubiquitin-like modifier 1
TDP2 tyrosyl-DNA phosphodiesterase 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
UBC ubiquitin C
UBE2I ubiquitin-conjugating enzyme E2I