FLT1 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description fms-related tyrosine kinase 1|This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009] (NCBI Entrez Gene Database, 2321)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_FLT1
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Genes

125 co-expressed genes for FLT1 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AANAT aralkylamine N-acetyltransferase
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
AQP5 aquaporin 5
AQP7 aquaporin 7
ARL3 ADP-ribosylation factor-like 3
ATP10B ATPase, class V, type 10B
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BCL2 B-cell CLL/lymphoma 2
BMP10 bone morphogenetic protein 10
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BRD1 bromodomain containing 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCKAR cholecystokinin A receptor
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD6 CD6 molecule
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CFH complement factor H
CLOCK clock circadian regulator
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CRHR1 corticotropin releasing hormone receptor 1
CTRL chymotrypsin-like
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DAPK2 death-associated protein kinase 2
DPT dermatopontin
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ESR1 estrogen receptor 1
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAM189A2 family with sequence similarity 189, member A2
FLT1 fms-related tyrosine kinase 1
FNTB farnesyltransferase, CAAX box, beta
FOSL1 FOS-like antigen 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GJB5 gap junction protein, beta 5, 31.1kDa
GLE1 GLE1 RNA export mediator
GPATCH8 G patch domain containing 8
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR19 G protein-coupled receptor 19
GPR3 G protein-coupled receptor 3
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIP2 glutamate receptor interacting protein 2
HAUS5 HAUS augmin-like complex, subunit 5
HCRT hypocretin (orexin) neuropeptide precursor
HOXD4 homeobox D4
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HSPB2 heat shock 27kDa protein 2
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL13 interleukin 13
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KANK3 KN motif and ankyrin repeat domains 3
KLHL18 kelch-like family member 18
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
KRT1 keratin 1, type II
KRT33A keratin 33A, type I
KRT33B keratin 33B, type I
KRT86 keratin 86, type II
LOC166994 integral membrane glycoprotein-like
LRRC48 leucine rich repeat containing 48
LTBP4 latent transforming growth factor beta binding protein 4
LTK leukocyte receptor tyrosine kinase
MAGEA9 melanoma antigen family A9
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MC5R melanocortin 5 receptor
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MON2 MON2 homolog (S. cerevisiae)
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MSX1 msh homeobox 1
MT4 metallothionein 4
MYO9B myosin IXB
MYOZ3 myozenin 3
NCKIPSD NCK interacting protein with SH3 domain
NEURL1 neuralized E3 ubiquitin protein ligase 1
NEUROD2 neuronal differentiation 2
NF1 neurofibromin 1
NOS2 nitric oxide synthase 2, inducible
NXPE3 neurexophilin and PC-esterase domain family, member 3
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
PAX7 paired box 7
PAX8 paired box 8
PAX9 paired box 9
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PIGR polymeric immunoglobulin receptor
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POU6F1 POU class 6 homeobox 1
PRSS16 protease, serine, 16 (thymus)
PSG1 pregnancy specific beta-1-glycoprotein 1
SCAPER S-phase cyclin A-associated protein in the ER
SIX3 SIX homeobox 3
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC22A24 solute carrier family 22, member 24
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SSTR5 somatostatin receptor 5
STK17A serine/threonine kinase 17a
SULT4A1 sulfotransferase family 4A, member 1
SYT5 synaptotagmin V
T T, brachyury homolog (mouse)
TACC2 transforming, acidic coiled-coil containing protein 2
TBC1D22A TBC1 domain family, member 22A
TBX1 T-box 1
TBX19 T-box 19
TBX5 T-box 5
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TGOLN2 trans-golgi network protein 2
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TM4SF5 transmembrane 4 L six family member 5
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
WT1 Wilms tumor 1
ZBTB40 zinc finger and BTB domain containing 40
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF157 zinc finger protein 157
ZNF500 zinc finger protein 500
ZNF592 zinc finger protein 592
ZNF710 zinc finger protein 710