| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | fms-related tyrosine kinase 3|This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015] (NCBI Entrez Gene Database, 2322) |
| External Link | https://ncbi.nlm.nih.gov/gene/2322 |
| Similar Terms | |
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498 genes differentially expressed following the FLT3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IFI27 | interferon, alpha-inducible protein 27 | 0.019326 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0179415 |
| ANXA1 | annexin A1 | 0.0153821 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0151844 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0151135 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0145275 |
| FCGBP | Fc fragment of IgG binding protein | 0.0139746 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.0138973 |
| ATF3 | activating transcription factor 3 | 0.0133538 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0132771 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.0129765 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0128311 |
| DEFB1 | defensin, beta 1 | 0.0127563 |
| TUBB2A | tubulin, beta 2A class IIa | 0.0124844 |
| PEG3 | paternally expressed 3 | 0.0124828 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0121954 |
| MME | membrane metallo-endopeptidase | 0.012111 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0120832 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0118057 |
| HSPA2 | heat shock 70kDa protein 2 | 0.0118054 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0114233 |
| RGS4 | regulator of G-protein signaling 4 | 0.0113972 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.01133 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.0112029 |
| RGCC | regulator of cell cycle | 0.0110654 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.0109694 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.01095 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.0109452 |
| TOX | thymocyte selection-associated high mobility group box | 0.0109422 |
| OPHN1 | oligophrenin 1 | 0.0108661 |
| CNTN1 | contactin 1 | 0.0105574 |
| EDN3 | endothelin 3 | 0.0105429 |
| MAB21L2 | mab-21-like 2 (C. elegans) | 0.0105421 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.0104913 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0104727 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0103944 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.0103727 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0103524 |
| MYO1C | myosin IC | 0.0103346 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.0102857 |
| CLTB | clathrin, light chain B | 0.0102658 |
| IFI44 | interferon-induced protein 44 | 0.0101157 |
| ADM | adrenomedullin | 0.0101131 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0100066 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.00996103 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00989007 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.00985894 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00977902 |
| MX1 | MX dynamin-like GTPase 1 | 0.00977635 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.0097106 |
| SPRR3 | small proline-rich protein 3 | 0.0097074 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.0096502 |
| RNF167 | ring finger protein 167 | 0.00962113 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00961098 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00960197 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00942913 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.009402 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00939455 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00939026 |
| CFI | complement factor I | 0.00938149 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.00933434 |
| MMP12 | matrix metallopeptidase 12 | 0.00931457 |
| IFI44L | interferon-induced protein 44-like | 0.00928866 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00925603 |
| PRNP | prion protein | 0.00924401 |
| DAXX | death-domain associated protein | 0.00916409 |
| RNASET2 | ribonuclease T2 | 0.00914916 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0091203 |
| KLK10 | kallikrein-related peptidase 10 | 0.00911817 |
| TPBG | trophoblast glycoprotein | 0.0091042 |
| MVP | major vault protein | 0.00907614 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00900742 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00899152 |
| OXTR | oxytocin receptor | 0.00894489 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00890736 |
| TFRC | transferrin receptor | 0.00876239 |
| MMP3 | matrix metallopeptidase 3 | 0.00875397 |
| COG7 | component of oligomeric golgi complex 7 | 0.00875104 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00874898 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0087146 |
| A2M | alpha-2-macroglobulin | 0.00868053 |
| S100A7 | S100 calcium binding protein A7 | 0.00858825 |
| RBM34 | RNA binding motif protein 34 | 0.00858694 |
| CLDN8 | claudin 8 | 0.00858645 |
| MT1X | metallothionein 1X | 0.00850448 |
| MUC16 | mucin 16, cell surface associated | 0.00845709 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00842952 |
| PITX3 | paired-like homeodomain 3 | 0.00836688 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00836507 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00835757 |
| LY96 | lymphocyte antigen 96 | 0.00834962 |
| SLC35G2 | solute carrier family 35, member G2 | 0.00833718 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.00829108 |
| SNCAIP | synuclein, alpha interacting protein | 0.00828296 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00827339 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00826875 |
| TRIM22 | tripartite motif containing 22 | 0.00823269 |
| AOC1 | amine oxidase, copper containing 1 | 0.00810058 |
| BTG3 | BTG family, member 3 | 0.00807944 |
| MT2A | metallothionein 2A | 0.00806435 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.00806403 |
| KRT23 | keratin 23, type I | 0.00801956 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00801601 |
| TMEM140 | transmembrane protein 140 | 0.00801534 |
| IL1B | interleukin 1, beta | 0.00797832 |
| CAST | calpastatin | 0.00795737 |
| BEX4 | brain expressed, X-linked 4 | 0.00795084 |
| XIC | X chromosome inactivation center | 0.00794117 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00793611 |
| NES | nestin | 0.00791283 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00791007 |
| PODXL | podocalyxin-like | 0.0079075 |
| TCTN2 | tectonic family member 2 | 0.0078777 |
| PLAT | plasminogen activator, tissue | 0.00786456 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00785095 |
| CCNG1 | cyclin G1 | 0.00784458 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00783832 |
| GYPC | glycophorin C (Gerbich blood group) | 0.00783155 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00782874 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.00782119 |
| MMP1 | matrix metallopeptidase 1 | 0.00781987 |
| RTP4 | receptor (chemosensory) transporter protein 4 | 0.00780231 |
| LRRN3 | leucine rich repeat neuronal 3 | 0.00780051 |
| GAB2 | GRB2-associated binding protein 2 | 0.0077995 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00779329 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00777959 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.00777823 |
| C3AR1 | complement component 3a receptor 1 | 0.00775855 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.00774383 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00771975 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00767485 |
| TRIM29 | tripartite motif containing 29 | 0.00765227 |
| XAF1 | XIAP associated factor 1 | 0.00762106 |
| RGS5 | regulator of G-protein signaling 5 | 0.00760015 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.00759718 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 0.00757793 |
| ABLIM1 | actin binding LIM protein 1 | 0.00754825 |
| AIM2 | absent in melanoma 2 | 0.00753321 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00752188 |
| RTCA | RNA 3'-terminal phosphate cyclase | 0.00750966 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00750643 |
| TMEM176A | transmembrane protein 176A | 0.00750365 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | 0.0074796 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | 0.00747525 |
| HTRA1 | HtrA serine peptidase 1 | 0.00746302 |
| DOK5 | docking protein 5 | 0.00744189 |
| CD53 | CD53 molecule | 0.00742389 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00741804 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.00740385 |
| MMD | monocyte to macrophage differentiation-associated | 0.00738113 |
| CLCA1 | chloride channel accessory 1 | 0.00737974 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00732585 |
| MMP10 | matrix metallopeptidase 10 | 0.00731929 |
| LEFTY1 | left-right determination factor 1 | 0.00731474 |
| PTPRO | protein tyrosine phosphatase, receptor type, O | 0.0073131 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.00731256 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.00728096 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0072648 |
| CA4 | carbonic anhydrase IV | 0.00723792 |
| LGALS9 | lectin, galactoside-binding, soluble, 9 | 0.00722019 |
| THBS1 | thrombospondin 1 | 0.00721255 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00719266 |
| MICB | MHC class I polypeptide-related sequence B | 0.00718538 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.00718181 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00717955 |
| MT1G | metallothionein 1G | 0.00717529 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00716599 |
| IQCG | IQ motif containing G | 0.00714174 |
| MX2 | MX dynamin-like GTPase 2 | 0.00713091 |
| ASS1 | argininosuccinate synthase 1 | 0.00712028 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00711193 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.00710732 |
| SP110 | SP110 nuclear body protein | 0.00709944 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.00708895 |
| LEPROT | leptin receptor overlapping transcript | 0.00707589 |
| PIGR | polymeric immunoglobulin receptor | 0.00706426 |
| MRPL19 | mitochondrial ribosomal protein L19 | 0.00706177 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | 0.0070443 |
| ACLY | ATP citrate lyase | 0.0069885 |
| FNDC3B | fibronectin type III domain containing 3B | 0.00696182 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00696133 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | 0.00695034 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.00692536 |
| FAM107A | family with sequence similarity 107, member A | 0.00692503 |
| STOM | stomatin | 0.00691253 |
| ZYX | zyxin | 0.00688495 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.00686416 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | 0.00686305 |
| STC1 | stanniocalcin 1 | 0.00686241 |
| FKBP5 | FK506 binding protein 5 | 0.00686066 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.00685645 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00685539 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0068491 |
| KLF6 | Kruppel-like factor 6 | 0.00683835 |
| MT1E | metallothionein 1E | 0.00679495 |
| MEN1 | multiple endocrine neoplasia I | 0.00678412 |
| ERP44 | endoplasmic reticulum protein 44 | 0.00678177 |
| LXN | latexin | 0.00677915 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00674653 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.00673423 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00672381 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | 0.00666592 |
| TSPAN3 | tetraspanin 3 | 0.00666562 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.00665722 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00665195 |
| ZG16 | zymogen granule protein 16 | 0.00664015 |
| BCL2A1 | BCL2-related protein A1 | 0.00663772 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.0066352 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.00662067 |
| GRAMD2B | GRAM domain containing 2B | 0.00660069 |
| AK4 | adenylate kinase 4 | 0.00658226 |
| REEP5 | receptor accessory protein 5 | 0.00658102 |
| C1QBP | complement component 1, q subcomponent binding protein | 0.00657834 |
| ATP10B | ATPase, class V, type 10B | 0.00654932 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00654133 |
| C3 | complement component 3 | 0.00652975 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | 0.00652174 |
| SATB2 | SATB homeobox 2 | 0.00651639 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | 0.006506 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00647963 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.00646904 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 0.00646744 |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.0064562 |
| CTSC | cathepsin C | 0.00644742 |
| ETHE1 | ethylmalonic encephalopathy 1 | 0.00644167 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0064361 |
| EXOC5 | exocyst complex component 5 | 0.00643077 |
| CA2 | carbonic anhydrase II | 0.00642185 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00641733 |
| EMP1 | epithelial membrane protein 1 | 0.00640733 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00640604 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00639149 |
| OPTN | optineurin | 0.00638262 |
| AGPS | alkylglycerone phosphate synthase | 0.00637919 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00637582 |
| MAGEA3 | melanoma antigen family A3 | 0.00635453 |
| MT1H | metallothionein 1H | 0.00634395 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00633539 |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) | 0.00633094 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.00632145 |
| SP100 | SP100 nuclear antigen | 0.00631815 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00627359 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00626265 |
| RCAN1 | regulator of calcineurin 1 | 0.00626065 |
| MYOF | myoferlin | 0.00624542 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00623409 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.00622856 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00622624 |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 | 0.00621828 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | 0.00621456 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | -0.0191081 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.015645 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.014551 |
| TMSB15A | thymosin beta 15a | -0.0140771 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.0128648 |
| DCLK1 | doublecortin-like kinase 1 | -0.0126099 |
| HOPX | HOP homeobox | -0.0123749 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.011979 |
| REEP1 | receptor accessory protein 1 | -0.0114851 |
| MSMB | microseminoprotein, beta- | -0.0112813 |
| GPX3 | glutathione peroxidase 3 | -0.0110114 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.0108844 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.0107565 |
| PCP4 | Purkinje cell protein 4 | -0.0106985 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.0106445 |
| S100P | S100 calcium binding protein P | -0.0104165 |
| APMAP | adipocyte plasma membrane associated protein | -0.0102897 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.01027 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.0102604 |
| LTF | lactotransferrin | -0.0102293 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.0101928 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | -0.0101032 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.010044 |
| RXRA | retinoid X receptor, alpha | -0.0100237 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.010018 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00992472 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00992119 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | -0.00966496 |
| GRB14 | growth factor receptor-bound protein 14 | -0.00966488 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00948965 |
| ANXA10 | annexin A10 | -0.00948799 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | -0.00939025 |
| TSPAN13 | tetraspanin 13 | -0.00937698 |
| BAD | BCL2-associated agonist of cell death | -0.00925093 |
| TPD52L1 | tumor protein D52-like 1 | -0.00924946 |
| RAPSN | receptor-associated protein of the synapse | -0.00921594 |
| PRKCZ | protein kinase C, zeta | -0.00911624 |
| PDLIM5 | PDZ and LIM domain 5 | -0.00907252 |
| NOTCH2NL | notch 2 N-terminal like | -0.00904476 |
| AHR | aryl hydrocarbon receptor | -0.0090082 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00899531 |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) | -0.00896215 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.0089535 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00892882 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00892025 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.00888046 |
| SEPTIN10 | septin 10 | -0.00887033 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00886064 |
| TXNIP | thioredoxin interacting protein | -0.00880704 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00878813 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00872982 |
| HAUS3 | HAUS augmin-like complex, subunit 3 | -0.00865944 |
| APOD | apolipoprotein D | -0.00865147 |
| FOXA1 | forkhead box A1 | -0.00856312 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | -0.00854561 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | -0.00852153 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00849901 |
| S100A4 | S100 calcium binding protein A4 | -0.00830906 |
| KAZN | kazrin, periplakin interacting protein | -0.00830596 |
| NOTCH2 | notch 2 | -0.00824891 |
| TSPAN12 | tetraspanin 12 | -0.00824293 |
| AGR2 | anterior gradient 2 | -0.00822725 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | -0.00808714 |
| ELN | elastin | -0.00806616 |
| PROM1 | prominin 1 | -0.0080496 |
| MB | myoglobin | -0.00802735 |
| CKM | creatine kinase, muscle | -0.00801109 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.00800337 |
| GSTA1 | glutathione S-transferase alpha 1 | -0.00797361 |
| SCAF4 | SR-related CTD-associated factor 4 | -0.00791064 |
| DVL1 | dishevelled segment polarity protein 1 | -0.00790037 |
| CCDC92 | coiled-coil domain containing 92 | -0.00788989 |
| MAGEB2 | melanoma antigen family B2 | -0.0078468 |
| LEPR | leptin receptor | -0.00780023 |
| DBF4 | DBF4 zinc finger | -0.00777919 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.00777579 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.00772216 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00771277 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00770762 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00767295 |
| THAP12 | THAP domain containing 12 | -0.00761278 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | -0.00753957 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | -0.00753384 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00753303 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00750866 |
| EXPH5 | exophilin 5 | -0.00749067 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 | -0.00748623 |
| GLB1L2 | galactosidase, beta 1-like 2 | -0.0074849 |
| ENO3 | enolase 3 (beta, muscle) | -0.0074668 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.00744729 |
| NNMT | nicotinamide N-methyltransferase | -0.00743203 |
| TFF1 | trefoil factor 1 | -0.00742192 |
| ZNF468 | zinc finger protein 468 | -0.00740912 |
| MYO5C | myosin VC | -0.00740867 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.00740278 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00737869 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.00736414 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -0.007345 |
| SFN | stratifin | -0.00733882 |
| PRC1 | protein regulator of cytokinesis 1 | -0.00733361 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.00730621 |
| ZNF329 | zinc finger protein 329 | -0.00729891 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | -0.00727441 |
| TRAPPC3 | trafficking protein particle complex 3 | -0.00723551 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 | -0.0072349 |
| NXN | nucleoredoxin | -0.00721338 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00720553 |
| CYB5A | cytochrome b5 type A (microsomal) | -0.00720469 |
| HRASLS | HRAS-like suppressor | -0.00718625 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.00714602 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.00713789 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta | -0.00713574 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | -0.00713327 |
| TOX3 | TOX high mobility group box family member 3 | -0.00711964 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00707488 |
| SC5D | sterol-C5-desaturase | -0.00706628 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00706116 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00705332 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00704416 |
| TDO2 | tryptophan 2,3-dioxygenase | -0.00703185 |
| EML3 | echinoderm microtubule associated protein like 3 | -0.00702645 |
| DPT | dermatopontin | -0.00702255 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00702027 |
| TMEM134 | transmembrane protein 134 | -0.00701519 |
| PERP | PERP, TP53 apoptosis effector | -0.00697647 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -0.00694936 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | -0.00694877 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | -0.00693082 |
| NADK | NAD kinase | -0.00692538 |
| STK26 | serine/threonine protein kinase 26 | -0.00691629 |
| CA3 | carbonic anhydrase III | -0.00690835 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.00689815 |
| COMP | cartilage oligomeric matrix protein | -0.00689652 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.00689537 |
| TTN | titin | -0.00688589 |
| EFNB2 | ephrin-B2 | -0.00688235 |
| PPL | periplakin | -0.00687317 |
| MLPH | melanophilin | -0.00684448 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00683923 |
| CEP76 | centrosomal protein 76kDa | -0.00681477 |
| TRAPPC4 | trafficking protein particle complex 4 | -0.00680413 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | -0.00680332 |
| SLC44A4 | solute carrier family 44, member 4 | -0.0068023 |
| ATMIN | ATM interactor | -0.00679086 |
| FBXO5 | F-box protein 5 | -0.00677142 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.00677013 |
| CRIP2 | cysteine-rich protein 2 | -0.00675882 |
| TM7SF2 | transmembrane 7 superfamily member 2 | -0.00674828 |
| KIAA0895 | KIAA0895 | -0.00674738 |
| CD1E | CD1e molecule | -0.00673161 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | -0.00672083 |
| RBM47 | RNA binding motif protein 47 | -0.00670847 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00670473 |
| SFTPB | surfactant protein B | -0.0066888 |
| LMNB2 | lamin B2 | -0.00668377 |
| CLGN | calmegin | -0.00667834 |
| NAXD | NAD(P)HX dehydratase | -0.00664552 |
| PDGFC | platelet derived growth factor C | -0.00664328 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.00664046 |
| ESRP2 | epithelial splicing regulatory protein 2 | -0.00663838 |
| TFAM | transcription factor A, mitochondrial | -0.00663774 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.00663202 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00662576 |
| LRP5 | low density lipoprotein receptor-related protein 5 | -0.00662463 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00662223 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0066221 |
| EDRF1 | erythroid differentiation regulatory factor 1 | -0.00661826 |
| TARDBP | TAR DNA binding protein | -0.0066104 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.0065814 |
| POMZP3 | POM121 and ZP3 fusion | -0.00657452 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00656781 |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger | -0.006543 |
| RAB25 | RAB25, member RAS oncogene family | -0.00654177 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.0065278 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00652037 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00651879 |
| CTSK | cathepsin K | -0.00649993 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.00649543 |
| ZNF226 | zinc finger protein 226 | -0.00647538 |
| CYP2C8 | cytochrome P450, family 2, subfamily C, polypeptide 8 | -0.00647201 |
| LSR | lipolysis stimulated lipoprotein receptor | -0.00646139 |
| PLA2G12A | phospholipase A2, group XIIA | -0.00645965 |
| PPIE | peptidylprolyl isomerase E (cyclophilin E) | -0.00645076 |
| HIST1H2BK | histone cluster 1, H2bk | -0.00643645 |
| FASN | fatty acid synthase | -0.00642932 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.00642579 |
| RUFY3 | RUN and FYVE domain containing 3 | -0.00641667 |
| GPSM2 | G-protein signaling modulator 2 | -0.0064115 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | -0.00636644 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00636207 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.00635211 |
| CALML5 | calmodulin-like 5 | -0.00634902 |
| EHBP1L1 | EH domain binding protein 1-like 1 | -0.00633371 |
| RPA1 | replication protein A1, 70kDa | -0.0063321 |
| FBXO3 | F-box protein 3 | -0.00630768 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0063061 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00629438 |
| KLHL41 | kelch-like family member 41 | -0.00628554 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.00627929 |
| E2F8 | E2F transcription factor 8 | -0.00627364 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | -0.00626013 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00625671 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 | -0.00624993 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | -0.00622472 |
| DHCR7 | 7-dehydrocholesterol reductase | -0.0062157 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00619403 |
| MEF2C | myocyte enhancer factor 2C | -0.00618221 |
| RAB40B | RAB40B, member RAS oncogene family | -0.0061797 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.00617193 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | -0.00616534 |
| CLDN4 | claudin 4 | -0.00612986 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | -0.00612767 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00610737 |
| MANSC1 | MANSC domain containing 1 | -0.00610158 |
| FOXM1 | forkhead box M1 | -0.00608152 |
| ANKRD10 | ankyrin repeat domain 10 | -0.00606987 |
| RAD51AP1 | RAD51 associated protein 1 | -0.00604484 |
| HMGN5 | high mobility group nucleosome binding domain 5 | -0.00604287 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00603684 |
| CTBP2 | C-terminal binding protein 2 | -0.00602112 |
| DES | desmin | -0.00602042 |
| COQ8A | coenzyme Q8A | -0.00601655 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00600328 |
| NMU | neuromedin U | -0.00598378 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | -0.00598106 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | -0.00598046 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | -0.00596902 |
| AMD1 | adenosylmethionine decarboxylase 1 | -0.00596402 |
| AMH | anti-Mullerian hormone | -0.00596058 |
| MYOT | myotilin | -0.00595885 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.00594313 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | -0.0059326 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00593174 |
| NELFB | negative elongation factor complex member B | -0.00592773 |
| NAPA | N-ethylmaleimide-sensitive factor attachment protein, alpha | -0.00591837 |
| ELOVL6 | ELOVL fatty acid elongase 6 | -0.00589821 |
| KIF5B | kinesin family member 5B | -0.00589676 |
| HOXC6 | homeobox C6 | -0.00589219 |
| FBXO11 | F-box protein 11 | -0.00589194 |
| DGKZ | diacylglycerol kinase, zeta | -0.00588978 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00588331 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | -0.00588304 |
| SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 | -0.00587519 |
| NOVA1 | neuro-oncological ventral antigen 1 | -0.00585663 |
| KANSL2 | KAT8 regulatory NSL complex subunit 2 | -0.00584925 |
| IL18 | interleukin 18 | -0.00584773 |
| MMP2 | matrix metallopeptidase 2 | -0.00584312 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -0.00583877 |
